{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,4]],"date-time":"2026-11-04T16:44:33Z","timestamp":1793810673654,"version":"4.6.1"},"reference-count":76,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,2,1]],"date-time":"2025-02-01T00:00:00Z","timestamp":1738368000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,2,1]],"date-time":"2025-02-01T00:00:00Z","timestamp":1738368000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,12,10]],"date-time":"2025-12-10T00:00:00Z","timestamp":1765324800000},"content-version":"am","delay-in-days":312,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,2,1]],"date-time":"2025-02-01T00:00:00Z","timestamp":1738368000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2025,2,1]],"date-time":"2025-02-01T00:00:00Z","timestamp":1738368000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,2,1]],"date-time":"2025-02-01T00:00:00Z","timestamp":1738368000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2025,2,1]],"date-time":"2025-02-01T00:00:00Z","timestamp":1738368000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,2,1]],"date-time":"2025-02-01T00:00:00Z","timestamp":1738368000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100020855","name":"University of Massachusetts Lowell","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100020855","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000066","name":"National Institute of Environmental Health Sciences","doi-asserted-by":"publisher","award":["R21 ES032882"],"award-info":[{"award-number":["R21 ES032882"]}],"id":[{"id":"10.13039\/100000066","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Toxicology and Applied Pharmacology"],"published-print":{"date-parts":[[2025,2]]},"DOI":"10.1016\/j.taap.2024.117188","type":"journal-article","created":{"date-parts":[[2024,12,6]],"date-time":"2024-12-06T02:52:55Z","timestamp":1733453575000},"page":"117188","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":10,"special_numbering":"C","title":["An oat fiber intervention for reducing PFAS body burden: A pilot study in male C57Bl\/6\u00a0J mice"],"prefix":"10.1016","volume":"495","author":[{"given":"Jennifer J.","family":"Schlezinger","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kushal","family":"Biswas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Audrey","family":"Garcia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wendy J.","family":"Heiger-Bernays","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dhimiter","family":"Bello","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"6","key":"10.1016\/j.taap.2024.117188_bb0005","doi-asserted-by":"crossref","first-page":"2365","DOI":"10.1007\/s00204-016-1888-3","article-title":"Activation of nuclear receptor CAR by an environmental pollutant perfluorooctanoic acid","volume":"91","author":"Abe","year":"2017","journal-title":"Arch. Toxicol."},{"key":"10.1016\/j.taap.2024.117188_bb0010","doi-asserted-by":"crossref","first-page":"246","DOI":"10.1016\/j.watres.2013.10.067","article-title":"Treatment of poly- and perfluoroalkyl substances in U.S. full-scale water treatment systems","volume":"51","author":"Appleman","year":"2014","journal-title":"Water Res."},{"key":"10.1016\/j.taap.2024.117188_bb0015","author":"ATSDR"},{"key":"10.1016\/j.taap.2024.117188_bb0020","doi-asserted-by":"crossref","DOI":"10.1016\/j.molmet.2022.101602","article-title":"Exposure to low-dose perfluorooctanoic acid promotes hepatic steatosis and disrupts the hepatic transcriptome in mice","volume":"66","author":"Attema","year":"2022","journal-title":"Mol. Metabol."},{"issue":"1","key":"10.1016\/j.taap.2024.117188_bb0025","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1093\/toxsci\/kfr142","article-title":"Perfluoroalkyl sulfonates cause alkyl chain length-dependent hepatic steatosis and hypolipidemia mainly by impairing lipoprotein production in APOE*3-Leiden CETP mice","volume":"123","author":"Bijland","year":"2011","journal-title":"Toxicol. Sci."},{"issue":"1","key":"10.1016\/j.taap.2024.117188_bb0030","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1136\/gut.2.1.23","article-title":"Studies on the site of fat absorption: 1. The sites of absorption of increasing doses of I-labelled triolein in the rat","volume":"2","author":"Booth","year":"1961","journal-title":"Gut"},{"issue":"5","key":"10.1016\/j.taap.2024.117188_bb0035","doi-asserted-by":"crossref","first-page":"3214","DOI":"10.1021\/acs.est.1c07176","article-title":"Effect of enterohepatic circulation on the accumulation of per- and Polyfluoroalkyl substances: evidence from experimental and computational studies","volume":"56","author":"Cao","year":"2022","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.taap.2024.117188_bb0040","author":"CDC"},{"issue":"4","key":"10.1016\/j.taap.2024.117188_bb0045","doi-asserted-by":"crossref","first-page":"428","DOI":"10.1016\/j.reprotox.2011.07.002","article-title":"Comparative pharmacokinetics of perfluorooctanesulfonate (PFOS) in rats, mice, and monkeys","volume":"33","author":"Chang","year":"2012","journal-title":"Reprod. Toxicol."},{"issue":"1","key":"10.1016\/j.taap.2024.117188_bb0050","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1093\/toxsci\/kfn147","article-title":"Perfluorocarboxylic acids induce cytochrome P450 enzymes in mouse liver through activation of PPAR-alpha and CAR transcription factors","volume":"106","author":"Cheng","year":"2008","journal-title":"Toxicol. Sci."},{"key":"10.1016\/j.taap.2024.117188_bb0055","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1016\/j.tox.2016.12.007","article-title":"Perfluoroalkyl acids-induced liver steatosis: effects on genes controlling lipid homeostasis","volume":"378","author":"Das","year":"2017","journal-title":"Toxicology"},{"issue":"8","key":"10.1016\/j.taap.2024.117188_bb0060","doi-asserted-by":"crossref","first-page":"695","DOI":"10.1016\/j.jnutbio.2009.04.003","article-title":"Beta-glucan extracts inhibit the in vitro intestinal uptake of long-chain fatty acids and cholesterol and down-regulate genes involved in lipogenesis and lipid transport in rats","volume":"21","author":"Drozdowski","year":"2010","journal-title":"J. Nutr. Biochem."},{"key":"10.1016\/j.taap.2024.117188_bb0065","doi-asserted-by":"crossref","DOI":"10.1016\/j.etap.2021.103650","article-title":"Perfluoroalkyl substance excretion: effects of organic anion-inhibiting and resin-binding drugs in a community setting","volume":"85","author":"Ducatman","year":"2021","journal-title":"Environ. Toxicol. Pharmacol."},{"key":"10.1016\/j.taap.2024.117188_bb0070","doi-asserted-by":"crossref","DOI":"10.1016\/j.envint.2020.106292","article-title":"The concentration of several perfluoroalkyl acids in serum appears to be reduced by dietary fiber","volume":"146","author":"Dzierlenga","year":"2021","journal-title":"Environ. Int."},{"issue":"1\u20133","key":"10.1016\/j.taap.2024.117188_bb0075","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1016\/j.tox.2011.12.015","article-title":"Evaluation of hepatic and thyroid responses in male Sprague Dawley rats for up to eighty-four days following seven days of dietary exposure to potassium perfluorooctanesulfonate","volume":"293","author":"Elcombe","year":"2012","journal-title":"Toxicology"},{"issue":"1","key":"10.1016\/j.taap.2024.117188_bb0080","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1539\/joh.14-0136-OA","article-title":"Toxicokinetics of perfluoroalkyl carboxylic acids with different carbon chain lengths in mice and humans","volume":"57","author":"Fujii","year":"2015","journal-title":"J. Occup. Health"},{"issue":"4","key":"10.1016\/j.taap.2024.117188_bb0085","doi-asserted-by":"crossref","DOI":"10.1001\/jamanetworkopen.2022.6257","article-title":"Effect of plasma and blood donations on levels of Perfluoroalkyl and Polyfluoroalkyl substances in firefighters in Australia: a randomized clinical trial","volume":"5","author":"Gasiorowski","year":"2022","journal-title":"JAMA Netw. Open"},{"issue":"7","key":"10.1016\/j.taap.2024.117188_bb0090","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1016\/j.puhe.2010.03.002","article-title":"Human detoxification of perfluorinated compounds","volume":"124","author":"Genuis","year":"2010","journal-title":"Public Health"},{"key":"10.1016\/j.taap.2024.117188_bb0095","doi-asserted-by":"crossref","DOI":"10.1155\/2013\/657849","article-title":"Gastrointestinal elimination of Perfluorinated compounds using cholestyramine and Chlorella pyrenoidosa","volume":"2013","author":"Genuis","year":"2013","journal-title":"ISRN Toxicol."},{"issue":"12","key":"10.1016\/j.taap.2024.117188_bb0100","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0114295","article-title":"Phlebotomy treatment for elimination of perfluoroalkyl acids in a highly exposed family: a retrospective case-series","volume":"9","author":"Genuis","year":"2014","journal-title":"PloS One"},{"issue":"2","key":"10.1016\/j.taap.2024.117188_bb0105","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1038\/s41575-020-00375-4","article-title":"Dietary fibre in gastrointestinal health and disease","volume":"18","author":"Gill","year":"2021","journal-title":"Nat. Rev. Gastroenterol. Hepatol."},{"key":"10.1016\/j.taap.2024.117188_bb0110","article-title":"Per and polyfluoroalkyl substances (PFAS) blood levels after contamination of a community water supply and comparison with 2013-2014 NHANES","author":"Graber","year":"2018","journal-title":"J. Expo. Sci. Environ. Epidemiol."},{"issue":"4","key":"10.1016\/j.taap.2024.117188_bb0115","doi-asserted-by":"crossref","DOI":"10.1016\/j.isci.2022.104020","article-title":"Implications of PFAS definitions using fluorinated pharmaceuticals","volume":"25","author":"Hammel","year":"2022","journal-title":"IScience"},{"issue":"2","key":"10.1016\/j.taap.2024.117188_bb0120","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1016\/j.etap.2007.04.003","article-title":"Biliary excretion and cerebrospinal fluid partition of perfluorooctanoate and perfluorooctane sulfonate in humans","volume":"24","author":"Harada","year":"2007","journal-title":"Environ. Toxicol. Pharmacol."},{"issue":"7","key":"10.1016\/j.taap.2024.117188_bb0125","doi-asserted-by":"crossref","first-page":"2014","DOI":"10.1016\/j.tjnut.2024.05.003","article-title":"Impact of plant-based dietary fibers on metabolic homeostasis in high-fat diet mice via alterations in the gut microbiota and metabolites","volume":"154","author":"Howard","year":"2024","journal-title":"J. Nutr."},{"key":"10.1016\/j.taap.2024.117188_bb0130","doi-asserted-by":"crossref","first-page":"8818160","DOI":"10.1155\/2020\/8818160","article-title":"Attenuation of Perfluorooctane sulfonate-induced steatohepatitis by grape seed Proanthocyanidin extract in mice","volume":"2020","author":"Huang","year":"2020","journal-title":"Biomed. Res. Int."},{"issue":"2","key":"10.1016\/j.taap.2024.117188_bb0135","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1080\/01480540600561361","article-title":"Absorption, distribution, and excretion of ammonium perfluorooctanoate (APFO) after oral administration to various species","volume":"29","author":"Hundley","year":"2006","journal-title":"Drug Chem. Toxicol."},{"key":"10.1016\/j.taap.2024.117188_bb0140","article-title":"Dietary reference intakes for energy","author":"IOM","year":"2005","journal-title":"Carbohydrate, Fiber, Fat, Fatty Acids, Cholesterol, Protein, and Amino Acids."},{"issue":"2","key":"10.1016\/j.taap.2024.117188_bb0145","first-page":"67","article-title":"Food ingredients that inhibit cholesterol absorption","volume":"22","author":"Jesch","year":"2017","journal-title":"Preventive Nutr. Food Sci."},{"issue":"6","key":"10.1016\/j.taap.2024.117188_bb0150","doi-asserted-by":"crossref","first-page":"972","DOI":"10.1016\/0272-0590(84)90235-5","article-title":"Cholestyramine-enhanced fecal elimination of carbon-14 in rats after administration of ammonium [14C]perfluorooctanoate or potassium [14C]perfluorooctanesulfonate","volume":"4","author":"Johnson","year":"1984","journal-title":"Fundamental Appl. Toxicol."},{"key":"10.1016\/j.taap.2024.117188_bb0155","article-title":"Effects of perfluoroalkyl carboxylic acids on the uptake of sulfobromophthalein via organic anion transporting polypeptides in human intestinal Caco-2 cells","volume":"24","author":"Kimura","year":"2020","journal-title":"Biochem. Biophys. Rep."},{"key":"10.1016\/j.taap.2024.117188_bb0160","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.tox.2019.01.017","article-title":"The effects of perfluorooctanoate on high fat diet induced non-alcoholic fatty liver disease in mice","volume":"416","author":"Li","year":"2019","journal-title":"Toxicology"},{"key":"10.1016\/j.taap.2024.117188_bb0165","article-title":"Dietary characteristics associated with plasma concentrations of per- and polyfluoroalkyl substances among adults with pre-diabetes: cross-sectional results from the diabetes prevention program trial","volume":"137","author":"Lin","year":"2020","journal-title":"Environ. Int."},{"key":"10.1016\/j.taap.2024.117188_bb0170","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1016\/j.chemosphere.2014.07.093","article-title":"The effect of ongoing blood loss on human serum concentrations of perfluorinated acids","volume":"118","author":"Lorber","year":"2015","journal-title":"Chemosphere"},{"issue":"2","key":"10.1016\/j.taap.2024.117188_bb0175","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1093\/toxsci\/kfn234","article-title":"Modeling single and repeated dose pharmacokinetics of PFOA in mice","volume":"107","author":"Lou","year":"2009","journal-title":"Toxicol. Sci."},{"issue":"10","key":"10.1016\/j.taap.2024.117188_bb0180","doi-asserted-by":"crossref","first-page":"1139","DOI":"10.1016\/S0002-8223(97)00275-7","article-title":"Database and quick methods of assessing typical dietary fiber intakes using data for 228 commonly consumed foods","volume":"97","author":"Marlett","year":"1997","journal-title":"J. Am. Dietetic Assoc."},{"issue":"19","key":"10.1016\/j.taap.2024.117188_bb0185","doi-asserted-by":"crossref","first-page":"3838","DOI":"10.1080\/10408398.2021.1994523","article-title":"The effect of cereal \u0392-glucan on body weight and adiposity: a review of efficacy and mechanism of action","volume":"63","author":"Mathews","year":"2023","journal-title":"Crit. Rev. Food Sci. Nutr."},{"key":"10.1016\/j.taap.2024.117188_bb0190","doi-asserted-by":"crossref","DOI":"10.1016\/j.envint.2024.108497","article-title":"Substantial decrease of PFAS with anion exchange resin treatment - a clinical cross-over trial","volume":"185","author":"M\u00f8ller","year":"2024","journal-title":"Environ. Int."},{"key":"10.1016\/j.taap.2024.117188_bb0195","doi-asserted-by":"crossref","DOI":"10.1016\/j.etap.2023.104062","article-title":"Effect of lifestyle-based lipid lowering interventions on the relationship between circulating levels of per-and polyfluoroalkyl substances and serum cholesterol","volume":"98","author":"Morgan","year":"2023","journal-title":"Environ. Toxicol. Pharmacol."},{"issue":"1","key":"10.1016\/j.taap.2024.117188_bb0200","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1007\/s00204-011-0704-3","article-title":"Modulation of ammonium perfluorooctanoate-induced hepatic damage by genetically different PPARalpha in mice","volume":"86","author":"Nakagawa","year":"2012","journal-title":"Arch. Toxicol."},{"issue":"1\u20132","key":"10.1016\/j.taap.2024.117188_bb0205","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/j.tox.2009.09.004","article-title":"Microgram-order ammonium perfluorooctanoate may activate mouse peroxisome proliferator-activated receptor \u03b1, but not human PPAR\u03b1","volume":"265","author":"Nakamura","year":"2009","journal-title":"Toxicology"},{"key":"10.1016\/j.taap.2024.117188_bb0210","author":"NASEM"},{"issue":"7","key":"10.1016\/j.taap.2024.117188_bb0215","doi-asserted-by":"crossref","first-page":"76002","DOI":"10.1289\/EHP11885","article-title":"A state-of-the-science review of interactions of per- and Polyfluoroalkyl substances (PFAS) with renal transporters in health and disease: implications for population variability in PFAS Toxicokinetics","volume":"131","author":"Niu","year":"2023","journal-title":"Environ. Health Perspect."},{"issue":"4","key":"10.1016\/j.taap.2024.117188_bb0220","doi-asserted-by":"crossref","first-page":"608","DOI":"10.1172\/JCI17305","article-title":"Muscle-specific PPARgamma-deficient mice develop increased adiposity and insulin resistance but respond to thiazolidinediones","volume":"112","author":"Norris","year":"2003","journal-title":"J. Clin. Invest."},{"issue":"2","key":"10.1016\/j.taap.2024.117188_bb0225","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1093\/toxsci\/kfaa148","article-title":"Perfluorooctanesulfonic acid and Perfluorohexanesulfonic acid Alter the blood Lipidome and the hepatic proteome in a murine model of diet-induced obesity","volume":"178","author":"Pfohl","year":"2020","journal-title":"Toxicol. Sci."},{"key":"10.1016\/j.taap.2024.117188_bb0230","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1016\/j.yrtph.2019.05.008","article-title":"Interspecies differences in perfluoroalkyl substances (PFAS) toxicokinetics and application to health-based criteria","volume":"106","author":"Pizzurro","year":"2019","journal-title":"Regulatory Toxicol. Pharmacol. RTP"},{"issue":"12","key":"10.1016\/j.taap.2024.117188_bb0235","doi-asserted-by":"crossref","DOI":"10.3390\/toxics11120963","article-title":"Hepatic transcriptome comparative in silico analysis reveals similar pathways and targets altered by legacy and alternative per- and Polyfluoroalkyl substances in mice","volume":"11","author":"Robarts","year":"2023","journal-title":"Toxics"},{"key":"10.1016\/j.taap.2024.117188_bb0240","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1016\/j.tox.2017.05.013","article-title":"PPARalpha-independent transcriptional targets of perfluoroalkyl acids revealed by transcript profiling","volume":"387","author":"Rosen","year":"2017","journal-title":"Toxicology"},{"key":"10.1016\/j.taap.2024.117188_bb0245","doi-asserted-by":"crossref","first-page":"328","DOI":"10.1016\/j.chemosphere.2014.07.092","article-title":"Inhalation and oral toxicokinetics of 6:2 FTOH and its metabolites in mammals","volume":"120","author":"Russell","year":"2015","journal-title":"Chemosphere"},{"key":"10.1016\/j.taap.2024.117188_bb0250","doi-asserted-by":"crossref","DOI":"10.1016\/j.chemosphere.2020.128359","article-title":"Isomers of emerging per- and polyfluoroalkyl substances in water and sediment from the cape fear river, North Carolina, USA","volume":"262","author":"Saleeby","year":"2021","journal-title":"Chemosphere"},{"key":"10.1016\/j.taap.2024.117188_bb0255","doi-asserted-by":"crossref","DOI":"10.1016\/j.taap.2020.115204","article-title":"Perfluorooctanoic acid activates multiple nuclear receptor pathways and skews expression of genes regulating cholesterol homeostasis in liver of humanized PPAR\u03b1 mice fed an American diet","volume":"405","author":"Schlezinger","year":"2020","journal-title":"Toxicol. Appl. Pharmacol."},{"key":"10.1016\/j.taap.2024.117188_bb0260","doi-asserted-by":"crossref","DOI":"10.1016\/j.taap.2021.115644","article-title":"Perfluorooctanoic acid induces liver and serum dyslipidemia in humanized PPAR\u03b1 mice fed an American diet","volume":"426","author":"Schlezinger","year":"2021","journal-title":"Toxicol. Appl. Pharmacol."},{"key":"10.1016\/j.taap.2024.117188_bb0265","first-page":"24311171","article-title":"Per- and Poly-fluoroalkyl substances (PFAS) in circulation in a Canadian population: their association with serum liver enzyme biomarkers and piloting a novel method to reduce serum PFAS","author":"Schlezinger","year":"2024","journal-title":"MedRxiv"},{"issue":"1\u20133","key":"10.1016\/j.taap.2024.117188_bb0270","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/S0300-483X(02)00511-5","article-title":"Sub-chronic dietary toxicity of potassium perfluorooctanesulfonate in rats","volume":"183","author":"Seacat","year":"2003","journal-title":"Toxicology"},{"key":"10.1016\/j.taap.2024.117188_bb0275","doi-asserted-by":"crossref","DOI":"10.1016\/j.envint.2021.106415","article-title":"Dietary patterns and PFAS plasma concentrations in childhood: project viva, USA","volume":"151","author":"Seshasayee","year":"2021","journal-title":"Environ. Int."},{"issue":"15","key":"10.1016\/j.taap.2024.117188_bb0280","doi-asserted-by":"crossref","DOI":"10.3390\/molecules26154559","article-title":"Polysaccharide structures and their hypocholesterolemic potential","volume":"26","author":"Silva","year":"2021","journal-title":"Molecules (Basel, Switzerland)"},{"key":"10.1016\/j.taap.2024.117188_bb0285","doi-asserted-by":"crossref","DOI":"10.1016\/j.tox.2021.153056","article-title":"The role of mouse and human peroxisome proliferator-activated receptor-\u03b1 in modulating the hepatic effects of perfluorooctane sulfonate in mice","volume":"465","author":"Su","year":"2022","journal-title":"Toxicology"},{"issue":"Pt 1","key":"10.1016\/j.taap.2024.117188_bb0290","article-title":"Dietary per- and polyfluoroalkyl substance (PFAS) exposure in adolescents: the HOME study","volume":"231","author":"Sultan","year":"2023","journal-title":"Environ. Res."},{"issue":"6","key":"10.1016\/j.taap.2024.117188_bb0295","doi-asserted-by":"crossref","first-page":"879","DOI":"10.1002\/oby.22472","article-title":"Are liquid sugars different from solid sugar in their ability to cause metabolic syndrome?","volume":"27","author":"Sundborn","year":"2019","journal-title":"Obesity (Silver spring Md.)"},{"issue":"4","key":"10.1016\/j.taap.2024.117188_bb0300","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1016\/j.reprotox.2011.07.004","article-title":"Comparative pharmacokinetics of perfluorohexanesulfonate (PFHxS) in rats, mice, and monkeys","volume":"33","author":"Sundstr\u00f6m","year":"2012","journal-title":"Reproduct. Toxicol. (Elmsford, N.Y.)"},{"issue":"4","key":"10.1016\/j.taap.2024.117188_bb0305","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0061409","article-title":"High fat diet feeding exaggerates perfluorooctanoic acid-induced liver injury in mice via modulating multiple metabolic pathways","volume":"8","author":"Tan","year":"2013","journal-title":"PloS One"},{"issue":"1\u20133","key":"10.1016\/j.taap.2024.117188_bb0310","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1016\/j.tox.2011.01.003","article-title":"Comparative pharmacokinetics of perfluorononanoic acid in rat and mouse","volume":"281","author":"Tatum-Gibbs","year":"2011","journal-title":"Toxicology"},{"issue":"2","key":"10.1016\/j.taap.2024.117188_bb0315","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1289\/ehp.1306707","article-title":"Polyfluoroalkyl chemicals and menopause among women 20-65 years of age (NHANES)","volume":"122","author":"Taylor","year":"2014","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.taap.2024.117188_bb0320","author":"USDA"},{"issue":"9","key":"10.1016\/j.taap.2024.117188_bb0325","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1248\/bpb1978.13.581","article-title":"Effects of chronic administration of perfluorooctanoic acid on fatty acid metabolism in rat liver: relationship among stearoyl-coenzyme a desaturase, 1-acylglycerophosphocholine acyltransferase, and acyl composition of microsomal phosphatidylcholine","volume":"13","author":"Uy-Yu","year":"1990","journal-title":"J. Pharmacobiodyn."},{"issue":"41","key":"10.1016\/j.taap.2024.117188_bb0330","doi-asserted-by":"crossref","first-page":"15348","DOI":"10.1021\/acs.est.2c08241","article-title":"Estimation of the half-lives of recently detected per- and Polyfluorinated alkyl ethers in an exposed community","volume":"57","author":"Wallis","year":"2023","journal-title":"Environ. Sci. Technol."},{"issue":"7","key":"10.1016\/j.taap.2024.117188_bb0335","doi-asserted-by":"crossref","first-page":"1092","DOI":"10.1016\/j.bbagen.2012.03.010","article-title":"PFOS-induced hepatic steatosis, the mechanistic actions on \u03b2-oxidation and lipid transport","volume":"1820","author":"Wan","year":"2012","journal-title":"Biochim. Biophys. Acta"},{"issue":"1","key":"10.1016\/j.taap.2024.117188_bb0340","doi-asserted-by":"crossref","first-page":"330","DOI":"10.1021\/pr500641b","article-title":"Integrated proteomic and miRNA transcriptional analysis reveals the hepatotoxicity mechanism of PFNA exposure in mice","volume":"14","author":"Wang","year":"2015","journal-title":"J. Proteome Res."},{"key":"10.1016\/j.taap.2024.117188_bb0345","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2024.173157","article-title":"Association of diet with per- and polyfluoroalkyl substances in plasma and human milk in the New Hampshire birth cohort study","volume":"933","author":"Wang","year":"2024","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.taap.2024.117188_bb0350","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/j.tox.2019.01.014","article-title":"Hepatic carboxylesterases are differentially regulated in PPARalpha-null mice treated with perfluorooctanoic acid","volume":"416","author":"Wen","year":"2019","journal-title":"Toxicology"},{"issue":"4","key":"10.1016\/j.taap.2024.117188_bb0355","doi-asserted-by":"crossref","first-page":"632","DOI":"10.1177\/0192623308318216","article-title":"Comparative hepatic effects of perfluorooctanoic acid and WY 14,643 in PPAR-alpha knockout and wild-type mice","volume":"36","author":"Wolf","year":"2008","journal-title":"Toxicol. Pathol."},{"issue":"15","key":"10.1016\/j.taap.2024.117188_bb0360","doi-asserted-by":"crossref","first-page":"8807","DOI":"10.1021\/es500796y","article-title":"Enhanced elimination of Perfluorooctane sulfonic acid by menstruating women: evidence from population-based pharmacokinetic modeling","volume":"48","author":"Wong","year":"2014","journal-title":"Environ. Sci. Technol."},{"issue":"10","key":"10.1016\/j.taap.2024.117188_bb0365","doi-asserted-by":"crossref","DOI":"10.3390\/nu14102043","article-title":"Effects of oat Beta-glucan intake on lipid profiles in Hypercholesterolemic adults: a systematic review and Meta-analysis of randomized controlled trials","volume":"14","author":"Yu","year":"2022","journal-title":"Nutrients"},{"key":"10.1016\/j.taap.2024.117188_bb0370","doi-asserted-by":"crossref","DOI":"10.1016\/j.envres.2022.115188","article-title":"A systematic evidence map of chronic inflammation and immunosuppression related to per- and polyfluoroalkyl substance (PFAS) exposure","volume":"220","author":"Zhang","year":"2023","journal-title":"Environ. Res."},{"issue":"1","key":"10.1016\/j.taap.2024.117188_bb0375","first-page":"84","article-title":"Organic anion transporting polypeptides contribute to the disposition of Perfluoroalkyl acids in humans and rats","volume":"156","author":"Zhao","year":"2017","journal-title":"Toxicol. Sci."},{"issue":"42","key":"10.1016\/j.taap.2024.117188_bb0380","doi-asserted-by":"crossref","first-page":"15782","DOI":"10.1021\/acs.est.2c06715","article-title":"Elevated levels of ultrashort- and short-chain Perfluoroalkyl acids in US homes and people","volume":"57","author":"Zheng","year":"2023","journal-title":"Environ. Sci. Technol."}],"container-title":["Toxicology and Applied Pharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0041008X24003879?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0041008X24003879?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,2,3]],"date-time":"2025-02-03T15:45:33Z","timestamp":1738597533000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0041008X24003879"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,2]]},"references-count":76,"alternative-id":["S0041008X24003879"],"URL":"https:\/\/doi.org\/10.1016\/j.taap.2024.117188","relation":{},"ISSN":["0041-008X"],"issn-type":[{"value":"0041-008X","type":"print"}],"subject":[],"published":{"date-parts":[[2025,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"An oat fiber intervention for reducing PFAS body burden: A pilot study in male C57Bl\/6\u00a0J mice","name":"articletitle","label":"Article Title"},{"value":"Toxicology and Applied Pharmacology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.taap.2024.117188","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"117188"}}