{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,17]],"date-time":"2026-02-17T02:40:54Z","timestamp":1771296054393,"version":"3.50.1"},"reference-count":48,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82260467"],"award-info":[{"award-number":["82260467"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100020205","name":"Health Commission of Jiangxi Province","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100020205","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004479","name":"Jiangxi Provincial Natural Science Foundation","doi-asserted-by":"publisher","award":["20224BAB206118"],"award-info":[{"award-number":["20224BAB206118"]}],"id":[{"id":"10.13039\/501100004479","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004479","name":"Jiangxi Provincial Natural Science Foundation","doi-asserted-by":"publisher","award":["20224BAB206061"],"award-info":[{"award-number":["20224BAB206061"]}],"id":[{"id":"10.13039\/501100004479","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Toxicology and Applied Pharmacology"],"published-print":{"date-parts":[[2026,2]]},"DOI":"10.1016\/j.taap.2025.117665","type":"journal-article","created":{"date-parts":[[2025,12,4]],"date-time":"2025-12-04T16:28:23Z","timestamp":1764865703000},"page":"117665","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"special_numbering":"C","title":["DEHP induces hepatic fibrosis through STAT3-SLC7A11-ROS axis"],"prefix":"10.1016","volume":"507","author":[{"given":"Siqin","family":"Liang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhiliang","family":"Xu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaoxiang","family":"You","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tinghao","family":"Yuan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jun","family":"He","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lei","family":"Mao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anan","family":"Jin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xinwen","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bo","family":"Yi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ming","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qiang","family":"Tu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bin","family":"Xu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.taap.2025.117665_bb0005","article-title":"Estimated daily intake and cumulative risk assessment of phthalates in the general Taiwanese after the 2011 DEHP food scandal","volume":"7","author":"Chang","year":"2017","journal-title":"Sci. Rep."},{"key":"10.1016\/j.taap.2025.117665_bb0010","doi-asserted-by":"crossref","first-page":"815","DOI":"10.1158\/1078-0432.CCR-22-0997","article-title":"Selectively targeting STAT3 using a small molecule inhibitor is a potential therapeutic strategy for pancreatic Cancer","volume":"29","author":"Chen","year":"2023","journal-title":"Clin. Cancer Res."},{"key":"10.1016\/j.taap.2025.117665_bb0015","doi-asserted-by":"crossref","first-page":"280","DOI":"10.1038\/s41568-021-00435-0","article-title":"The role of ROS in tumour development and progression","volume":"22","author":"Cheung","year":"2022","journal-title":"Nat. Rev. Cancer"},{"key":"10.1016\/j.taap.2025.117665_bb0020","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1016\/j.envres.2019.03.037","article-title":"Di(2-ethylhexyl) phthalate (DEHP) increases proliferation of epithelial breast cancer cells through progesterone receptor dysregulation","volume":"173","author":"Crobeddu","year":"2019","journal-title":"Environ. Res."},{"key":"10.1016\/j.taap.2025.117665_bb0025","doi-asserted-by":"crossref","first-page":"3631","DOI":"10.1038\/s41467-020-17399-8","article-title":"Basement membrane damage by ROS- and JNK-mediated Mmp2 activation drives macrophage recruitment to overgrown tissue","volume":"11","author":"Diwanji","year":"2020","journal-title":"Nat. Commun."},{"key":"10.1016\/j.taap.2025.117665_bb0030","doi-asserted-by":"crossref","DOI":"10.1016\/j.redox.2023.102887","article-title":"CypD induced ROS output promotes intracranial aneurysm formation and rupture by 8-OHdG\/NLRP3\/MMP9 pathway","volume":"67","author":"Fan","year":"2023","journal-title":"Redox Biol."},{"key":"10.1016\/j.taap.2025.117665_bb0035","doi-asserted-by":"crossref","first-page":"e28","DOI":"10.1097\/MPG.0000000000001813","article-title":"Di (2-Ethylhexyl) phthalate and its role in developing cholestasis: an in vitro study on different liver cell types","volume":"66","author":"Gaitantzi","year":"2018","journal-title":"J. Pediatr. Gastroenterol. Nutr."},{"key":"10.1016\/j.taap.2025.117665_bb0040","doi-asserted-by":"crossref","first-page":"452","DOI":"10.1186\/s12951-023-02110-y","article-title":"Pericyte-derived exosomal miR-210 improves mitochondrial function and inhibits lipid peroxidation in vascular endothelial cells after traumatic spinal cord injury by activating JAK1\/STAT3 signaling pathway","volume":"21","author":"Gao","year":"2023","journal-title":"J. Nanobiotechnol."},{"key":"10.1016\/j.taap.2025.117665_bb0045","doi-asserted-by":"crossref","first-page":"416","DOI":"10.1016\/j.envpol.2015.10.009","article-title":"p53-dependent apoptosis contributes to di-(2-ethylhexyl) phthalate-induced hepatotoxicity","volume":"208","author":"Ha","year":"2016","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.taap.2025.117665_bb0050","doi-asserted-by":"crossref","first-page":"1651","DOI":"10.1007\/s00204-015-1619-1","article-title":"Hepatic and intestinal glucuronidation of mono(2-ethylhexyl) phthalate, an active metabolite of di(2-ethylhexyl) phthalate, in humans, dogs, rats, and mice: an in vitro analysis using microsomal fractions","volume":"90","author":"Hanioka","year":"2016","journal-title":"Arch. Toxicol."},{"key":"10.1016\/j.taap.2025.117665_bb0055","doi-asserted-by":"crossref","first-page":"2422","DOI":"10.7150\/ijbs.92749","article-title":"Oxidative stress promotes liver fibrosis by modulating the microRNA-144 and SIN3A-p38 pathways in hepatic stellate cells","volume":"20","author":"Hao","year":"2024","journal-title":"Int. J. Biol. Sci."},{"key":"10.1016\/j.taap.2025.117665_bb0060","doi-asserted-by":"crossref","first-page":"15487","DOI":"10.1021\/acs.jmedchem.2c01554","article-title":"Discovery of a highly potent and orally bioavailable STAT3 dual phosphorylation inhibitor for pancreatic cancer treatment","volume":"65","author":"He","year":"2022","journal-title":"J. Med. Chem."},{"key":"10.1016\/j.taap.2025.117665_bb0065","doi-asserted-by":"crossref","DOI":"10.1016\/j.ecoenv.2024.116866","article-title":"Elucidating the mechanism of plasticizers inducing breast cancer through network toxicology and molecular docking analysis","volume":"284","author":"He","year":"2024","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"10.1016\/j.taap.2025.117665_bb0070","doi-asserted-by":"crossref","DOI":"10.1016\/j.chemosphere.2024.142711","article-title":"Network toxicological and molecular docking to investigate the mechanisms of toxicity of agricultural chemical Thiabendazole","volume":"363","author":"He","year":"2024","journal-title":"Chemosphere"},{"key":"10.1016\/j.taap.2025.117665_bb0075","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1146\/annurev-pathol-011110-130246","article-title":"Pathogenesis of liver fibrosis","volume":"6","author":"Hernandez-Gea","year":"2011","journal-title":"Annu. Rev. Pathol."},{"key":"10.1016\/j.taap.2025.117665_bb0080","doi-asserted-by":"crossref","DOI":"10.1016\/j.ecoenv.2021.112889","article-title":"Exposure to DEHP induces testis toxicity and injury through the ROS\/mTOR\/NLRP3 signaling pathway in immature rats","volume":"227","author":"Hong","year":"2021","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"10.1016\/j.taap.2025.117665_bb0085","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1016\/j.cbi.2018.07.008","article-title":"New insights into TGF-beta\/Smad signaling in tissue fibrosis","volume":"292","author":"Hu","year":"2018","journal-title":"Chem. Biol. Interact."},{"key":"10.1016\/j.taap.2025.117665_bb0090","doi-asserted-by":"crossref","DOI":"10.1016\/j.redox.2021.102051","article-title":"Nox2 impairs VEGF-A-induced angiogenesis in placenta via mitochondrial ROS-STAT3 pathway","volume":"45","author":"Hu","year":"2021","journal-title":"Redox Biol."},{"key":"10.1016\/j.taap.2025.117665_bb0095","doi-asserted-by":"crossref","DOI":"10.1016\/j.ecoenv.2020.111872","article-title":"SO(2) derivatives induce dysfunction in human trophoblasts via inhibiting ROS\/IL-6\/STAT3 pathway","volume":"210","author":"Hu","year":"2021","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"10.1016\/j.taap.2025.117665_bb0100","doi-asserted-by":"crossref","DOI":"10.1016\/j.tox.2024.153847","article-title":"Analysis of environmental pollutant bisphenol F elicited prostate injury targets and underlying mechanisms through network toxicology, molecular docking, and multi-level bioinformatics data integration","volume":"506","author":"Huang","year":"2024","journal-title":"Toxicology"},{"key":"10.1016\/j.taap.2025.117665_bb0105","doi-asserted-by":"crossref","first-page":"9337","DOI":"10.1021\/acs.jafc.5c00224","article-title":"Quercetin alleviates Pyroptosis and necroptosis triggered on by DEHP exposure in Bursa of Fabricius in chicken by the ROS\/MAPK\/NF-kappaB pathway","volume":"73","author":"Huang","year":"2025","journal-title":"J. Agric. Food Chem."},{"key":"10.1016\/j.taap.2025.117665_bb0110","doi-asserted-by":"crossref","first-page":"539","DOI":"10.1172\/JCI30542","article-title":"Models of liver fibrosis: exploring the dynamic nature of inflammation and repair in a solid organ","volume":"117","author":"Iredale","year":"2007","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.taap.2025.117665_bb0115","doi-asserted-by":"crossref","DOI":"10.1016\/j.redox.2020.101600","article-title":"Curcumin blunts epithelial-mesenchymal transition of hepatocytes to alleviate hepatic fibrosis through regulating oxidative stress and autophagy","volume":"36","author":"Kong","year":"2020","journal-title":"Redox Biol."},{"key":"10.1016\/j.taap.2025.117665_bb0120","doi-asserted-by":"crossref","DOI":"10.1016\/j.envpol.2021.116933","article-title":"Multiple bioanalytical methods reveal a thyroid-disrupting mechanism related to the membrane receptor integrin alpha(v)beta(3)","volume":"279","author":"Kong","year":"2021","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.taap.2025.117665_bb0125","doi-asserted-by":"crossref","first-page":"308","DOI":"10.1007\/s11033-025-10423-4","article-title":"Morin hydrate treatment minimizes Di(2-ethylhexyl) phthalate-induced uterine fibrosis, oxidative stress, and apoptosis in mice","volume":"52","author":"Kumar","year":"2025","journal-title":"Mol. Biol. Rep."},{"key":"10.1016\/j.taap.2025.117665_bb0130","doi-asserted-by":"crossref","first-page":"1056","DOI":"10.7150\/ijbs.7.1056","article-title":"Diverse roles of TGF-beta\/Smads in renal fibrosis and inflammation","volume":"7","author":"Lan","year":"2011","journal-title":"Int. J. Biol. Sci."},{"key":"10.1016\/j.taap.2025.117665_bb0135","doi-asserted-by":"crossref","first-page":"2979","DOI":"10.2174\/092986710792064992","article-title":"Materials degradation in PVC medical devices, DEHP leaching and neonatal outcomes","volume":"17","author":"Latini","year":"2010","journal-title":"Curr. Med. Chem."},{"key":"10.1016\/j.taap.2025.117665_bb0140","doi-asserted-by":"crossref","first-page":"1211","DOI":"10.1007\/s00204-015-1539-0","article-title":"Maternal exposure to di-(2-ethylhexyl) phthalate exposure deregulates blood pressure, adiposity, cholesterol metabolism and social interaction in mouse offspring","volume":"90","author":"Lee","year":"2016","journal-title":"Arch. Toxicol."},{"key":"10.1016\/j.taap.2025.117665_bb0145","article-title":"Long-term exposure to low-dose Di-(2-ethylhexyl) phthalate impairs cholesterol metabolism in hepatic stellate cells and exacerbates liver Librosis","volume":"17","author":"Lee","year":"2020","journal-title":"Int. J. Environ. Res. Public Health"},{"key":"10.1016\/j.taap.2025.117665_bb0150","doi-asserted-by":"crossref","DOI":"10.1016\/j.ecoenv.2023.115798","article-title":"Prenatal to peripubertal exposure to Di(2-ethylhexyl) phthalate induced endometrial atrophy and fibrosis in female mice","volume":"269","author":"Lee","year":"2024","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"10.1016\/j.taap.2025.117665_bb0155","doi-asserted-by":"crossref","DOI":"10.1016\/j.redox.2019.101254","article-title":"PINK1-parkin pathway of mitophagy protects against contrast-induced acute kidney injury via decreasing mitochondrial ROS and NLRP3 inflammasome activation","volume":"26","author":"Lin","year":"2019","journal-title":"Redox Biol."},{"key":"10.1016\/j.taap.2025.117665_bb0160","doi-asserted-by":"crossref","first-page":"1923","DOI":"10.1002\/tox.24068","article-title":"Polystyrene microplastics mediate cell cycle arrest, apoptosis, and autophagy in the G2\/M phase through ROS in grass carp kidney cells","volume":"39","author":"Lu","year":"2024","journal-title":"Environ. Toxicol."},{"key":"10.1016\/j.taap.2025.117665_bb0165","doi-asserted-by":"crossref","DOI":"10.1016\/j.pestbp.2024.106153","article-title":"New insights into zinc alleviating renal toxicity of arsenic-exposed carp (Cyprinus carpio) through YAP-TFR\/ROS signaling pathway","volume":"205","author":"Lu","year":"2024","journal-title":"Pestic. Biochem. Physiol."},{"key":"10.1016\/j.taap.2025.117665_bb0170","doi-asserted-by":"crossref","DOI":"10.1016\/j.redox.2024.103159","article-title":"SLC7A11-ROS\/alphaKG-AMPK axis regulates liver inflammation through mitophagy and impairs liver fibrosis and NASH progression","volume":"72","author":"Lv","year":"2024","journal-title":"Redox Biol."},{"key":"10.1016\/j.taap.2025.117665_bb0175","doi-asserted-by":"crossref","DOI":"10.3390\/biom9100528","article-title":"Mesoporous silica nanoparticles trigger liver and kidney injury and fibrosis via altering TLR4\/NF-kappaB, JAK2\/STAT3 and Nrf2\/HO-1 signaling in rats","volume":"9","author":"Mahmoud","year":"2019","journal-title":"Biomolecules"},{"key":"10.1016\/j.taap.2025.117665_bb0180","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1016\/j.ecoenv.2018.08.050","article-title":"PM2.5 induces liver fibrosis via triggering ROS-mediated mitophagy","volume":"167","author":"Qiu","year":"2019","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"10.1016\/j.taap.2025.117665_bb0185","doi-asserted-by":"crossref","first-page":"4932","DOI":"10.1002\/ptr.7959","article-title":"Extracellular matrix turnover: phytochemicals target and modulate the dual role of matrix metalloproteinases (MMPs) in liver fibrosis","volume":"37","author":"Sabir","year":"2023","journal-title":"Phytother. Res."},{"key":"10.1016\/j.taap.2025.117665_bb0190","doi-asserted-by":"crossref","first-page":"18967","DOI":"10.1074\/jbc.M314037200","article-title":"Structural requirements for signal transducer and activator of transcription 3 binding to phosphotyrosine ligands containing the YXXQ motif","volume":"279","author":"Shao","year":"2004","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.taap.2025.117665_bb0195","doi-asserted-by":"crossref","DOI":"10.1016\/j.intimp.2020.106637","article-title":"ROS-dependent inhibition of the PI3K\/Akt\/mTOR signaling is required for Oroxylin a to exert anti-inflammatory activity in liver fibrosis","volume":"85","author":"Shen","year":"2020","journal-title":"Int. Immunopharmacol."},{"key":"10.1016\/j.taap.2025.117665_bb0200","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1159\/000534106","article-title":"Green tea polyphenols alleviate kidney injury induced by Di(2-Ethylhexyl) phthalate in mice","volume":"55","author":"Shi","year":"2024","journal-title":"Am. J. Nephrol."},{"key":"10.1016\/j.taap.2025.117665_bb0205","doi-asserted-by":"crossref","DOI":"10.3390\/cimb47070557","article-title":"MMP-9 activation via ROS\/NF-kappaB signaling in colorectal Cancer progression: molecular insights and prognostic-therapeutic perspectives","volume":"47","author":"Veljkovic","year":"2025","journal-title":"Curr. Issues Mol. Biol."},{"key":"10.1016\/j.taap.2025.117665_bb0210","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1093\/toxsci\/kfy094","article-title":"Plasticizer Di-(2-Ethylhexyl)phthalate induces epithelial-to-mesenchymal transition and renal fibrosis in vitro and in vivo","volume":"164","author":"Wu","year":"2018","journal-title":"Toxicol. Sci."},{"key":"10.1016\/j.taap.2025.117665_bb0215","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1038\/s41419-022-04806-9","article-title":"Osteopontin promotes hepatocellular carcinoma progression through inducing JAK2\/STAT3\/NOX1-mediated ROS production","volume":"13","author":"Wu","year":"2022","journal-title":"Cell Death Dis."},{"key":"10.1016\/j.taap.2025.117665_bb0220","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2023.161962","article-title":"Polystyrene-microplastics and DEHP co-exposure induced DNA damage, cell cycle arrest and necroptosis of ovarian granulosa cells in mice by promoting ROS production","volume":"871","author":"Wu","year":"2023","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.taap.2025.117665_bb0225","doi-asserted-by":"crossref","first-page":"1094","DOI":"10.1111\/cns.14085","article-title":"Alpinetin inhibits neuroinflammation and neuronal apoptosis via targeting the JAK2\/STAT3 signaling pathway in spinal cord injury","volume":"29","author":"Xiao","year":"2023","journal-title":"CNS Neurosci. Ther."},{"key":"10.1016\/j.taap.2025.117665_bb0230","doi-asserted-by":"crossref","DOI":"10.1016\/j.chemosphere.2022.133925","article-title":"MEHP promotes liver fibrosis by down-regulating STAT5A in BRL-3A hepatocytes","volume":"295","author":"Zhang","year":"2022","journal-title":"Chemosphere"},{"key":"10.1016\/j.taap.2025.117665_bb0235","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1016\/j.etap.2019.03.008","article-title":"Di(2-ethylhexyl) phthalate promotes hepatic fibrosis by regulation of oxidative stress and inflammation responses in rats","volume":"68","author":"Zhao","year":"2019","journal-title":"Environ. Toxicol. Pharmacol."},{"key":"10.1016\/j.taap.2025.117665_bb0240","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1016\/j.freeradbiomed.2022.09.012","article-title":"Disruption of histamine\/H(1)R-STAT3-SLC7A11 axis exacerbates doxorubicin-induced cardiac ferroptosis","volume":"192","author":"Zhu","year":"2022","journal-title":"Free Radic. Biol. Med."}],"container-title":["Toxicology and Applied Pharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0041008X25004417?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0041008X25004417?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,1,22]],"date-time":"2026-01-22T17:38:07Z","timestamp":1769103487000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0041008X25004417"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,2]]},"references-count":48,"alternative-id":["S0041008X25004417"],"URL":"https:\/\/doi.org\/10.1016\/j.taap.2025.117665","relation":{},"ISSN":["0041-008X"],"issn-type":[{"value":"0041-008X","type":"print"}],"subject":[],"published":{"date-parts":[[2026,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"DEHP induces hepatic fibrosis through STAT3-SLC7A11-ROS axis","name":"articletitle","label":"Article Title"},{"value":"Toxicology and Applied Pharmacology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.taap.2025.117665","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"117665"}}