{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,23]],"date-time":"2026-01-23T22:38:55Z","timestamp":1769207935181,"version":"3.49.0"},"reference-count":33,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2016,5,1]],"date-time":"2016-05-01T00:00:00Z","timestamp":1462060800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2016,5,1]],"date-time":"2016-05-01T00:00:00Z","timestamp":1462060800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81202493"],"award-info":[{"award-number":["81202493"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81273481"],"award-info":[{"award-number":["81273481"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81460170"],"award-info":[{"award-number":["81460170"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"name":"National Science and Technology Major Project for Significant New Drugs Development","award":["2013ZX09507005"],"award-info":[{"award-number":["2013ZX09507005"]}]},{"DOI":"10.13039\/100007219","name":"Shanghai Natural Science Foundation","doi-asserted-by":"publisher","award":["15ZR1409400"],"award-info":[{"award-number":["15ZR1409400"]}],"id":[{"id":"10.13039\/100007219","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Talanta"],"published-print":{"date-parts":[[2016,5]]},"DOI":"10.1016\/j.talanta.2016.01.014","type":"journal-article","created":{"date-parts":[[2016,1,11]],"date-time":"2016-01-11T01:31:32Z","timestamp":1452475892000},"page":"172-178","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":14,"special_numbering":"C","title":["Hypercrosslinked strong cation-exchange polymers for selective extraction of serum purine metabolites associated with gout"],"prefix":"10.1016","volume":"151","author":[{"given":"Yating","family":"Xu","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ju","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hongyang","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Min","family":"Jiang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lingling","family":"Cao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Min","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wei","family":"Sun","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shengli","family":"Ruan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ping","family":"Hu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.talanta.2016.01.014_bib1","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1016\/j.trac.2014.03.011","article-title":"Recent advances in solid-phase sorbents for sample preparation prior to chromatographic analysis","volume":"59","author":"Wen","year":"2014","journal-title":"Trac-Trends Anal. Chem."},{"key":"10.1016\/j.talanta.2016.01.014_bib2","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.talanta.2011.12.044","article-title":"Extraction and preconcentration techniques for chromatographic determination of chlorophenols in environmental and food samples","volume":"89","author":"de Morais","year":"2012","journal-title":"Talanta"},{"key":"10.1016\/j.talanta.2016.01.014_bib3","series-title":"Analytical solid-phase extraction","author":"Fritz","year":"1999"},{"key":"10.1016\/j.talanta.2016.01.014_bib4","first-page":"677","article-title":"Solid phase extraction technique-Trends, opportunities and applications","volume":"15","author":"Zwir-Ferenc","year":"2006","journal-title":"Pol. J. Env. Stud."},{"key":"10.1016\/j.talanta.2016.01.014_bib5","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1007\/BF02491931","article-title":"Mechanistic study of the sorption properties of Oasis HLB and its use in solid-phase extraction","volume":"56","author":"Dias","year":"2002","journal-title":"Chromatographia"},{"key":"10.1016\/j.talanta.2016.01.014_bib6","doi-asserted-by":"crossref","first-page":"394","DOI":"10.1016\/j.trac.2005.01.012","article-title":"New hydrophilic materials for solid-phase extraction","volume":"24","author":"Fontanals","year":"2005","journal-title":"Trac-Trends Anal. Chem."},{"key":"10.1016\/j.talanta.2016.01.014_bib7","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1016\/j.chroma.2003.10.076","article-title":"Solid-phase extraction of polar compounds with a hydrophilic copolymeric sorbent","volume":"1030","author":"Fontanals","year":"2004","journal-title":"J. Chromatogr. A"},{"key":"10.1016\/j.talanta.2016.01.014_bib8","doi-asserted-by":"crossref","first-page":"3793","DOI":"10.1016\/j.polymer.2010.05.045","article-title":"Macroporous polymeric sorbents with high selectivity for separation of phenols","volume":"51","author":"Qiu","year":"2010","journal-title":"Polymer"},{"key":"10.1016\/j.talanta.2016.01.014_bib9","doi-asserted-by":"crossref","first-page":"765","DOI":"10.1016\/j.trac.2010.03.015","article-title":"Mixed-mode ion-exchange polymeric sorbents: dual-phase materials that improve selectivity and capacity","volume":"29","author":"Fontanals","year":"2010","journal-title":"Trac-Trends Anal. Chem."},{"key":"10.1016\/j.talanta.2016.01.014_bib10","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1016\/j.chroma.2006.11.077","article-title":"New materials in sorptive extraction techniques for polar compounds","volume":"1152","author":"Fontanals","year":"2007","journal-title":"J. Chromatogr. A"},{"key":"10.1016\/j.talanta.2016.01.014_bib11","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1016\/j.chroma.2008.01.076","article-title":"Functionalization of divinylbenzene\/N-vinylpyrrolidone copolymer particles: ion exchangers for solid phase extraction","volume":"1191","author":"Brousmiche","year":"2008","journal-title":"J. Chromatogr. A"},{"key":"10.1016\/j.talanta.2016.01.014_bib12","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1016\/j.chroma.2014.02.087","article-title":"Selective determination of antimycotic drugs in environmental water samples by mixed-mode solid-phase extraction and liquid chromatography quadrupole time-of-flight mass spectrometry","volume":"1339","author":"Casado","year":"2014","journal-title":"J. Chromatogr. A"},{"key":"10.1016\/j.talanta.2016.01.014_bib13","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/j.chroma.2015.10.004","article-title":"Selective determination of COXIBs in environmental water samples by mixed-mode solid phase extraction and liquid chromatography quadrupole time-of-flight mass spectrometry","volume":"1420","author":"Trinanes","year":"2015","journal-title":"J. Chromatogr. A"},{"key":"10.1016\/j.talanta.2016.01.014_bib14","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1016\/j.talanta.2015.02.053","article-title":"A novel mixed-mode solid phase extraction coupled with LC-MS\/MS for the re-evaluation of free 3-nitrotyrosine in human plasma as an oxidative stress biomarker","volume":"140","author":"Li","year":"2015","journal-title":"Talanta"},{"key":"10.1016\/j.talanta.2016.01.014_bib15","doi-asserted-by":"crossref","first-page":"1437","DOI":"10.1002\/jssc.201201069","article-title":"Mixed-mode SPE for a multi-residue analysis of benzodiazepines in whole blood using rapid GC with negative-ion chemical ionization MS","volume":"36","author":"Karlonas","year":"2013","journal-title":"J. Sep. Sci."},{"key":"10.1016\/j.talanta.2016.01.014_bib16","doi-asserted-by":"crossref","first-page":"7914","DOI":"10.1016\/j.chroma.2011.09.005","article-title":"High-purity isolation of anthocyanins mixtures from fruits and vegetables-A novel solid-phase extraction method using mixed mode cation-exchange chromatography","volume":"1218","author":"He","year":"2011","journal-title":"J. Chromatogr. A"},{"key":"10.1016\/j.talanta.2016.01.014_bib17","doi-asserted-by":"crossref","first-page":"2687","DOI":"10.1016\/j.foodchem.2012.07.057","article-title":"Rapid mixed mode solid phase extraction method for the determination of acrylamide in roasted coffee by HPLC-MS\/MS","volume":"135","author":"Bortolomeazzi","year":"2012","journal-title":"Food Chem."},{"key":"10.1016\/j.talanta.2016.01.014_bib18","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/j.talanta.2013.03.068","article-title":"Analysis of gibberellins as free acids by ultra performance liquid chromatography-tandem mass spectrometry","volume":"112","author":"Urbanova","year":"2013","journal-title":"Talanta"},{"key":"10.1016\/j.talanta.2016.01.014_bib19","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/j.chroma.2008.10.124","article-title":"Hypercrosslinked polymer microspheres with weak anion-exchange character: preparation of the microspheres and their applications in pH-tuneable, selective extractions of analytes from complex environmental samples","volume":"1215","author":"Fontanals","year":"2008","journal-title":"J. Chromatogr. A"},{"key":"10.1016\/j.talanta.2016.01.014_bib20","doi-asserted-by":"crossref","first-page":"1575","DOI":"10.1016\/j.chroma.2010.01.037","article-title":"Synthesis and application of hypercrosslinked polymers with weak cation-exchange character for the selective extraction of basic pharmaceuticals from complex environmental water samples","volume":"1217","author":"Bratkowska","year":"2010","journal-title":"J. Chromatogr. A"},{"key":"10.1016\/j.talanta.2016.01.014_bib21","doi-asserted-by":"crossref","first-page":"2621","DOI":"10.1002\/jssc.201200451","article-title":"Hypercrosslinked strong anion-exchange resin for extraction of acidic pharmaceuticals from environmental water","volume":"35","author":"Bratkowska","year":"2012","journal-title":"J. Sep. Sci."},{"key":"10.1016\/j.talanta.2016.01.014_bib22","doi-asserted-by":"crossref","first-page":"939","DOI":"10.1016\/j.reactfunctpolym.2012.08.003","article-title":"Synthesis and characterization of microporous polymer microspheres with strong cation-exchange character","volume":"72","author":"Cormack","year":"2012","journal-title":"React. Funct. Polym."},{"key":"10.1016\/j.talanta.2016.01.014_bib23","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1016\/j.chroma.2004.02.049","article-title":"New hydrophilic polymeric resin based on 4-vinylpyridine-divinylbenzene for solid-phase extraction of polar compounds from water","volume":"1035","author":"Fontanals","year":"2004","journal-title":"J. Chromatogr. A"},{"key":"10.1016\/j.talanta.2016.01.014_bib24","doi-asserted-by":"crossref","first-page":"3238","DOI":"10.1016\/j.chroma.2009.08.091","article-title":"Hydrophilic hypercrosslinked polymeric sorbents for the solid-phase extraction of polar contaminants from water","volume":"1217","author":"Bratkowska","year":"2010","journal-title":"J. Chromatogr. A"},{"key":"10.1016\/j.talanta.2016.01.014_bib25","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/j.chroma.2014.03.068","article-title":"Evaluation of strong cation-exchange polymers for the determination of drugs by solid-phase extraction-liquid chromatography-tandem mass spectrometry","volume":"1343","author":"Fontanals","year":"2014","journal-title":"J. Chromatogr. A"},{"key":"10.1016\/j.talanta.2016.01.014_bib26","doi-asserted-by":"crossref","first-page":"1298","DOI":"10.1002\/adma.200702237","article-title":"Synthesis of spherical ultra-high-surface-area monodisperse amphipathic polymer sponges in the low-micrometer size range","volume":"20","author":"Fontanals","year":"2008","journal-title":"Adv. Mater."},{"key":"10.1016\/j.talanta.2016.01.014_bib27","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1080\/15421401003720140","article-title":"Chemical recycling of polystyrene. Sulfonation with different sulfonation agents","volume":"523","author":"Sulkowski","year":"2010","journal-title":"Mol. Cryst. Liq. Cryst."},{"key":"10.1016\/j.talanta.2016.01.014_bib28","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1002\/jssc.201300964","volume":"37","author":"Chen","year":"2014","journal-title":"J. Sep. Sci."},{"key":"10.1016\/j.talanta.2016.01.014_bib29","doi-asserted-by":"crossref","first-page":"1742","DOI":"10.1373\/clinchem.2004.040261","article-title":"Purine metabolites in gout and asymptomatic hyperuricemia: analysis by HPLC-electrospray tandem mass spectrometry","volume":"51","author":"Zhao","year":"2005","journal-title":"Clin. Chem."},{"key":"10.1016\/j.talanta.2016.01.014_bib30","doi-asserted-by":"crossref","first-page":"1930","DOI":"10.1016\/j.jchromb.2009.05.047","article-title":"Ultraviolet and tandem mass spectrometry for simultaneous quantification of 21 pivotal metabolites in plasma from patients with diabetic nephropathy","volume":"877","author":"Xia","year":"2009","journal-title":"J. Chromatogr. B"},{"key":"10.1016\/j.talanta.2016.01.014_bib31","doi-asserted-by":"crossref","first-page":"696","DOI":"10.1136\/ard.56.11.696a","article-title":"Serum uric acid in acute gout","volume":"56","author":"Logan","year":"1997","journal-title":"Ann. Rheum. Dis."},{"key":"10.1016\/j.talanta.2016.01.014_bib32","first-page":"1950","article-title":"The inflammatory process in the mechanism of decreased serum uric acid concentrations during acute gouty arthritis","volume":"29","author":"Urano","year":"2002","journal-title":"J. Rheumatol."},{"key":"10.1016\/j.talanta.2016.01.014_bib33","doi-asserted-by":"crossref","first-page":"499","DOI":"10.7326\/0003-4819-143-7-200510040-00009","article-title":"Pathogenesis of gout","volume":"143","author":"Choi","year":"2005","journal-title":"Ann. Intern. Med."}],"container-title":["Talanta"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S003991401630011X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S003991401630011X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,22]],"date-time":"2025-09-22T12:13:55Z","timestamp":1758543235000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S003991401630011X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,5]]},"references-count":33,"alternative-id":["S003991401630011X"],"URL":"https:\/\/doi.org\/10.1016\/j.talanta.2016.01.014","relation":{},"ISSN":["0039-9140"],"issn-type":[{"value":"0039-9140","type":"print"}],"subject":[],"published":{"date-parts":[[2016,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Hypercrosslinked strong cation-exchange polymers for selective extraction of serum purine metabolites associated with gout","name":"articletitle","label":"Article Title"},{"value":"Talanta","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.talanta.2016.01.014","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2016 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}