{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T04:38:16Z","timestamp":1780461496420,"version":"3.54.1"},"reference-count":43,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2018,7,1]],"date-time":"2018-07-01T00:00:00Z","timestamp":1530403200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2018,7,1]],"date-time":"2018-07-01T00:00:00Z","timestamp":1530403200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100001824","name":"Grantov\u00c3\u00a1 Agentura \u00c4\u008cesk\u00c3\u00a9 Republiky","doi-asserted-by":"publisher","award":["301\/17-05409S"],"award-info":[{"award-number":["301\/17-05409S"]}],"id":[{"id":"10.13039\/501100001824","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007397","name":"Univerzita Karlova v Praze","doi-asserted-by":"publisher","award":["SVV 260 412"],"award-info":[{"award-number":["SVV 260 412"]}],"id":[{"id":"10.13039\/100007397","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Talanta"],"published-print":{"date-parts":[[2018,7]]},"DOI":"10.1016\/j.talanta.2018.02.101","type":"journal-article","created":{"date-parts":[[2018,3,5]],"date-time":"2018-03-05T20:20:06Z","timestamp":1520281206000},"page":"162-172","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":49,"special_numbering":"C","title":["Direct-immersion single-drop microextraction and in-drop stirring microextraction for the determination of nanomolar concentrations of lead using automated Lab-In-Syringe technique"],"prefix":"10.1016","volume":"184","author":[{"given":"Ivana H.","family":"\u0160r\u00e1mkov\u00e1","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2337-9634","authenticated-orcid":false,"given":"Burkhard","family":"Horstkotte","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kate\u0159ina","family":"Fikarov\u00e1","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hana","family":"Sklen\u00e1\u0159ov\u00e1","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Petr","family":"Solich","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.talanta.2018.02.101_bib1","doi-asserted-by":"crossref","first-page":"2042","DOI":"10.1021\/ac00109a023","article-title":"Liquid droplet. A renewable gas sampling interface","volume":"67","author":"Liu","year":"1995","journal-title":"Anal. Chem."},{"key":"10.1016\/j.talanta.2018.02.101_bib2","doi-asserted-by":"crossref","first-page":"2236","DOI":"10.1021\/ac960042z","article-title":"Solvent microextraction into a single drop","volume":"68","author":"Jeannot","year":"1996","journal-title":"Anal. Chem."},{"key":"10.1016\/j.talanta.2018.02.101_bib3","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.chroma.2006.03.007","article-title":"Determination of organic compounds in water using dispersive liquid\u2013liquid microextraction","volume":"1116","author":"Rezaee","year":"2006","journal-title":"J. Chromatogr. A"},{"key":"10.1016\/j.talanta.2018.02.101_bib4","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1016\/j.trac.2014.12.011","article-title":"The role of green extraction techniques in Green analytical chemistry","volume":"71","author":"Armenta","year":"2015","journal-title":"TrAC Trends Anal. Chem."},{"key":"10.1016\/j.talanta.2018.02.101_bib5","doi-asserted-by":"crossref","first-page":"286","DOI":"10.1016\/j.aca.2006.12.049","article-title":"A new liquid-phase microextraction method based on solidification of floating organic drop","volume":"585","author":"Zanjani","year":"2007","journal-title":"Anal. Chim. Acta"},{"key":"10.1016\/j.talanta.2018.02.101_bib6","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1016\/j.aca.2015.11.038","article-title":"Automation of static and dynamic non-dispersive liquid phase microextraction. Part 1: approaches based on extractant drop-, plug-, film- and microflow-formation","volume":"906","author":"Alexovi\u010d","year":"2016","journal-title":"Anal. Chim. Acta"},{"key":"10.1016\/j.talanta.2018.02.101_bib7","doi-asserted-by":"crossref","first-page":"1674","DOI":"10.1039\/b103493f","article-title":"Headspace extraction of alcohols into a single drop","volume":"126","author":"Tankeviciute","year":"2001","journal-title":"Analyst"},{"key":"10.1016\/j.talanta.2018.02.101_bib8","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1016\/j.talanta.2016.05.027","article-title":"A novel procedure for phase separation in dispersive liquid-liquid microextraction based on solidification of the aqueous phase","volume":"156","author":"March","year":"2016","journal-title":"Talanta"},{"key":"10.1016\/j.talanta.2018.02.101_bib9","doi-asserted-by":"crossref","first-page":"2326","DOI":"10.1016\/j.chroma.2009.10.089","article-title":"Single drop microextraction-development, applications and future trends","volume":"1217","author":"Jeannot","year":"2010","journal-title":"J. Chromatogr. A"},{"key":"10.1016\/j.talanta.2018.02.101_bib10","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1016\/j.aca.2013.05.049","article-title":"In-syringe-stirring: a novel approach for magnetic stirring-assisted dispersive liquid-liquid microextraction","volume":"788","author":"Horstkotte","year":"2013","journal-title":"Anal. Chim. Acta"},{"key":"10.1016\/j.talanta.2018.02.101_bib11","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/j.aca.2014.04.031","article-title":"Automated in-syringe single-drop head-space micro-extraction applied to the determination of ethanol in wine samples","volume":"828","author":"\u0160r\u00e1mkov\u00e1","year":"2014","journal-title":"Anal. Chim. Acta"},{"key":"10.1016\/j.talanta.2018.02.101_bib12","doi-asserted-by":"crossref","first-page":"694","DOI":"10.1016\/j.talanta.2015.04.076","article-title":"On-line lab-in-syringe cloud point extraction for the spectrophotometric determination of antimony","volume":"148","author":"Frizzarin","year":"2016","journal-title":"Talanta"},{"key":"10.1016\/j.talanta.2018.02.101_bib13","doi-asserted-by":"crossref","first-page":"7545","DOI":"10.1021\/acs.analchem.5b01993","article-title":"Automatic in-syringe dispersive microsolid phase extraction using magnetic metal\u2013organic frameworks","volume":"87","author":"Maya","year":"2015","journal-title":"Anal. Chem."},{"key":"10.1016\/j.talanta.2018.02.101_bib14","doi-asserted-by":"crossref","first-page":"6761","DOI":"10.1007\/s00216-013-7111-y","article-title":"In-syringe magnetic-stirring-assisted liquid-liquid microextraction for the spectrophotometric determination of Cr(VI) in waters","volume":"405","author":"Henr\u00edquez","year":"2013","journal-title":"Anal. Bioanal. Chem."},{"key":"10.1016\/j.talanta.2018.02.101_bib15","doi-asserted-by":"crossref","first-page":"909","DOI":"10.1007\/s00216-012-6159-4","article-title":"Lab in a syringe: fully automated dispersive liquid-liquid microextraction with integrated spectrophotometric detection","volume":"404","author":"Maya","year":"2012","journal-title":"Anal. Bioanal. Chem."},{"key":"10.1016\/j.talanta.2018.02.101_bib16","unstructured":"World Health Organization, Exposure to lead: A major public health concern, in: Preventing disease through healthy environment. World Health Organization, Geneva, 2010."},{"key":"10.1016\/j.talanta.2018.02.101_bib17","unstructured":"United States Environmental Protection Agency, National Primary Drinking Water Regulation, 2009."},{"key":"10.1016\/j.talanta.2018.02.101_bib18","unstructured":"The Council of the European Union, Directive 98\/83\/EC of 3 November 1998 on the quality of water intended for human consumption. OJ C, 1998, pp. 32\u201354."},{"key":"10.1016\/j.talanta.2018.02.101_bib19","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1016\/j.aca.2003.08.030","article-title":"Exploiting sequential injection analysis with bead injection and lab-on-valve for determination of lead using electrothermal atomic absorption spectrometry","volume":"499","author":"Ampan","year":"2003","journal-title":"Anal. Chim. Acta"},{"key":"10.1016\/j.talanta.2018.02.101_bib20","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1016\/j.talanta.2009.03.005","article-title":"On-line sequential injection dispersive liquid-liquid microextraction system for flame atomic absorption spectrometric determination of copper and lead in water samples","volume":"79","author":"Anthemidis","year":"2009","journal-title":"Talanta"},{"key":"10.1016\/j.talanta.2018.02.101_bib21","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1016\/j.jhazmat.2011.01.123","article-title":"Determination of lead in environmental waters with dispersive liquid-liquid microextraction prior to atomic fluorescence spectrometry","volume":"189","author":"Zhou","year":"2011","journal-title":"J. Hazard. Mater."},{"key":"10.1016\/j.talanta.2018.02.101_bib22","doi-asserted-by":"crossref","first-page":"1638","DOI":"10.1016\/j.talanta.2009.09.059","article-title":"Temperature-controlled ionic liquid-liquid-phase microextraction for the pre-concentration of lead from environmental samples prior to flame atomic absorption spectrometry","volume":"80","author":"Bai","year":"2010","journal-title":"Talanta"},{"key":"10.1016\/j.talanta.2018.02.101_bib23","doi-asserted-by":"crossref","first-page":"825","DOI":"10.4028\/www.scientific.net\/AMR.829.825","article-title":"Preconcentration and determination of lead by solidification of floated organic drop coupled with Nanodrop spectrophotometry","volume":"829","author":"Mazloomifar","year":"2014","journal-title":"Adv. Mater. Res."},{"key":"10.1016\/j.talanta.2018.02.101_bib24","doi-asserted-by":"crossref","first-page":"800","DOI":"10.1016\/j.talanta.2007.07.010","article-title":"Single drop micro-extraction with O,O-diethyl dithiophosphate for the determination of lead by electrothermal atomic absorption spectrometry","volume":"74","author":"Maltez","year":"2008","journal-title":"Talanta"},{"key":"10.1016\/j.talanta.2018.02.101_bib25","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1007\/s00604-007-0785-0","article-title":"Determination of trace Cd and Pb in natural waters by direct single drop microextraction combined with electrothermal atomic absorption spectrometry","volume":"161","author":"Jiang","year":"2007","journal-title":"Microchim. Acta"},{"key":"10.1016\/j.talanta.2018.02.101_bib26","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1016\/j.aca.2008.06.033","article-title":"A novel separation\/preconcentration system based on solidification of floating organic drop microextraction for determination of lead by graphite furnace atomic absorption spectrometry","volume":"623","author":"Dadfarnia","year":"2008","journal-title":"Anal. Chim. Acta"},{"key":"10.1016\/j.talanta.2018.02.101_bib27","doi-asserted-by":"crossref","first-page":"846","DOI":"10.1016\/j.talanta.2004.08.018","article-title":"Automatic flow procedure based on multicommutation exploiting liquid-liquid extraction for spectrophotometric lead determination in plant material","volume":"65","author":"Comitre","year":"2005","journal-title":"Talanta"},{"key":"10.1016\/j.talanta.2018.02.101_bib28","doi-asserted-by":"crossref","first-page":"1203","DOI":"10.1016\/j.talanta.2004.06.020","article-title":"Determination of lead(II), copper(II), zinc(II), cobalt(II), cadmium(II), iron(III), mercury(II) using sequential injection extractions","volume":"64","author":"van Staden","year":"2004","journal-title":"Talanta"},{"key":"10.1016\/j.talanta.2018.02.101_bib29","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1016\/j.aca.2015.08.021","article-title":"Micro solid phase spectrophotometry in a sequential injection lab-on-valve platform for cadmium, zinc, and copper determination in freshwaters","volume":"891","author":"Santos","year":"2015","journal-title":"Anal. Chim. Acta"},{"key":"10.1016\/j.talanta.2018.02.101_bib30","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1016\/j.talanta.2003.11.012","article-title":"A sensitive spectrophotometric method for lead determination by flow injection analysis with on-line preconcentration","volume":"63","author":"Di Nezio","year":"2004","journal-title":"Talanta"},{"key":"10.1016\/j.talanta.2018.02.101_bib31","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1016\/j.talanta.2003.08.009","article-title":"A flow system for the spectrophotometric determination of lead in different types of waters using ion-exchange for pre-concentration and elimination of interferences","volume":"62","author":"Mesquita","year":"2004","journal-title":"Talanta"},{"key":"10.1016\/j.talanta.2018.02.101_bib32","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1155\/2006\/269568","article-title":"A simple spectrophotometric method for the determination of trace level lead in biological samples in the presence of aqueous micellar solutions","volume":"20","author":"Khan","year":"2006","journal-title":"Spectroscopy"},{"key":"10.1016\/j.talanta.2018.02.101_bib33","unstructured":"J. Fries, H. Getrost, Organic Reagents for Trace Analysis, E. Merck, Darmstadt, Germany, 1977."},{"key":"10.1016\/j.talanta.2018.02.101_bib34","doi-asserted-by":"crossref","first-page":"3787","DOI":"10.1021\/acs.analchem.7b00400","article-title":"Fully automatic in-syringe magnetic stirring-assisted dispersive liquid liquid microextraction hyphenated to high-temperature torch integrated sample introduction system-inductively coupled plasma spectrometer with direct injection of the organic phase","volume":"89","author":"S\u00e1nchez","year":"2017","journal-title":"Anal. Chem."},{"key":"10.1016\/j.talanta.2018.02.101_bib35","doi-asserted-by":"crossref","first-page":"684","DOI":"10.1021\/ac60009a022","article-title":"Improved dithizone method for determination of lead","volume":"19","author":"Snyder","year":"1947","journal-title":"Anal. Chem."},{"key":"10.1016\/j.talanta.2018.02.101_bib36","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1016\/j.talanta.2014.04.091","article-title":"An automatic countercurrent liquid-liquid micro-extraction system coupled with atomic absorption spectrometry for metal determination","volume":"133","author":"Mitani","year":"2015","journal-title":"Talanta"},{"key":"10.1016\/j.talanta.2018.02.101_bib37","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1016\/S0039-9140(00)00624-X","article-title":"Flow injection spectrophotometric analysis of lead in human saliva for monitoring environmental pollution","volume":"54","author":"Luconi","year":"2001","journal-title":"Talanta"},{"key":"10.1016\/j.talanta.2018.02.101_bib38","doi-asserted-by":"crossref","first-page":"330","DOI":"10.1016\/j.saa.2009.10.035","article-title":"The determination of trace lead in drinking water by flow injection spectrophotometry","volume":"75","author":"Dai","year":"2010","journal-title":"Spectrochim. Acta Part A Mol. Biomol. Spectrosc."},{"key":"10.1016\/j.talanta.2018.02.101_bib39","doi-asserted-by":"crossref","first-page":"709","DOI":"10.1016\/j.talanta.2010.01.001","article-title":"Flow injection spectrophotometric determination of lead using 1,5-diphenylthiocarbazone in aqueous micellar","volume":"81","author":"Ruengsitagoon","year":"2010","journal-title":"Talanta"},{"key":"10.1016\/j.talanta.2018.02.101_bib40","first-page":"211","article-title":"Flow injection on-line separation and spectrophotometric determination of traces of lead in environmental samples","volume":"22","author":"Tomioka","year":"2003","journal-title":"Environ. Chem."},{"key":"10.1016\/j.talanta.2018.02.101_bib41","doi-asserted-by":"crossref","first-page":"679","DOI":"10.2116\/analsci.20.679","article-title":"Sequential injection analysis of lead using time-based colorimetric detection and preconcentration on an anionic-exchange resin","volume":"20","author":"Nestor Z\u00e1rate Aracama","year":"2004","journal-title":"Anal. Sci."},{"key":"10.1016\/j.talanta.2018.02.101_bib42","doi-asserted-by":"crossref","first-page":"998","DOI":"10.1007\/s11426-011-4262-6","article-title":"On-line solid-phase extraction using alizarin violet functionalized silica gel for determination of trace lead in environmental samples and wastewater by sequential injection spectrophotometry","volume":"54","author":"Fan","year":"2011","journal-title":"Sci. China Chem."},{"key":"10.1016\/j.talanta.2018.02.101_bib43","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1016\/j.talanta.2015.05.005","article-title":"Screening of cadmium and lead in potentially contaminated waters using a spectrophotometric sequential injection lab-on-valve methodology","volume":"143","author":"Santos","year":"2015","journal-title":"Talanta"}],"container-title":["Talanta"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0039914018302108?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0039914018302108?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,22]],"date-time":"2025-09-22T12:17:36Z","timestamp":1758543456000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0039914018302108"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,7]]},"references-count":43,"alternative-id":["S0039914018302108"],"URL":"https:\/\/doi.org\/10.1016\/j.talanta.2018.02.101","relation":{},"ISSN":["0039-9140"],"issn-type":[{"value":"0039-9140","type":"print"}],"subject":[],"published":{"date-parts":[[2018,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Direct-immersion single-drop microextraction and in-drop stirring microextraction for the determination of nanomolar concentrations of lead using automated Lab-In-Syringe technique","name":"articletitle","label":"Article Title"},{"value":"Talanta","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.talanta.2018.02.101","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}