{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T18:21:27Z","timestamp":1793125287640,"version":"4.5.0"},"reference-count":37,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2018,7,1]],"date-time":"2018-07-01T00:00:00Z","timestamp":1530403200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2018,7,1]],"date-time":"2018-07-01T00:00:00Z","timestamp":1530403200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Talanta"],"published-print":{"date-parts":[[2018,7]]},"DOI":"10.1016\/j.talanta.2018.03.001","type":"journal-article","created":{"date-parts":[[2018,3,6]],"date-time":"2018-03-06T03:09:00Z","timestamp":1520305740000},"page":"369-374","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":30,"special_numbering":"C","title":["Evaluation of 11 ionic liquids as potential extraction solvents for benzodiazepines from whole blood using liquid-liquid microextraction combined with LC-MS\/MS"],"prefix":"10.1016","volume":"184","author":[{"given":"Marieke","family":"De Boeck","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giacomo","family":"Damilano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wim","family":"Dehaen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jan","family":"Tytgat","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eva","family":"Cuypers","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.talanta.2018.03.001_bib1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.chroma.2017.04.012","article-title":"Non-conventional solvents in liquid phase microextraction and aqueous biphasic systems","volume":"1500","author":"An","year":"2017","journal-title":"J. Chromatogr. A"},{"key":"10.1016\/j.talanta.2018.03.001_bib2","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1016\/j.talanta.2013.10.050","article-title":"Green aspects, developments and perspectives of liquid phase microextraction techniques","volume":"119","author":"Spietelun","year":"2014","journal-title":"Talanta"},{"key":"10.1016\/j.talanta.2018.03.001_bib3","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.aca.2017.05.012","article-title":"New horizons in the extraction of bioactive compounds using deep eutectic solvents: a review","volume":"979","author":"Zainal-Abidin","year":"2017","journal-title":"Anal. Chim. Acta"},{"key":"10.1016\/j.talanta.2018.03.001_bib4","doi-asserted-by":"crossref","first-page":"1784","DOI":"10.1002\/cssc.201301192","article-title":"Ionic liquids and deep eutectic mixtures: sustainable solvents for extraction processes","volume":"7","author":"Pena-Pereira","year":"2014","journal-title":"ChemSusChem"},{"key":"10.1016\/j.talanta.2018.03.001_bib5","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1002\/jssc.201700848","article-title":"Recent progress of task-specific ionic liquids in chiral resolution and extraction of biological samples and metal ions","volume":"41","author":"Wu","year":"2018","journal-title":"J. Sep. Sci."},{"key":"10.1016\/j.talanta.2018.03.001_bib6","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1016\/j.chemosphere.2016.06.004","article-title":"How the structure of ionic liquid affects its toxicity to Vibrio fischeri?","volume":"159","author":"Grzonkowska","year":"2016","journal-title":"Chemosphere"},{"key":"10.1016\/j.talanta.2018.03.001_bib7","doi-asserted-by":"crossref","first-page":"2321","DOI":"10.1002\/cssc.201700261","article-title":"Environmental impact of ionic liquids: recent advances in (Eco)toxicology and (Bio)degradability","volume":"10","author":"Costa","year":"2017","journal-title":"ChemSusChem"},{"key":"10.1016\/j.talanta.2018.03.001_bib8","doi-asserted-by":"crossref","first-page":"1072","DOI":"10.1246\/cl.2004.1072","article-title":"Task-specific ionic liquids","volume":"33","author":"Davis","year":"2004","journal-title":"Chem. Lett."},{"key":"10.1016\/j.talanta.2018.03.001_bib9","doi-asserted-by":"crossref","first-page":"1196","DOI":"10.1002\/adma.200902184","article-title":"New frontiers in materials science opened by ionic liquids","volume":"22","author":"Torimoto","year":"2010","journal-title":"Adv. Mater."},{"key":"10.1016\/j.talanta.2018.03.001_bib10","doi-asserted-by":"crossref","first-page":"1487","DOI":"10.1007\/s10098-013-0660-0","article-title":"Applications of ionic liquids in organic synthesis and catalysis","volume":"16","author":"Qureshi","year":"2014","journal-title":"Clean Technol. Environ. Policy"},{"key":"10.1016\/j.talanta.2018.03.001_bib11","doi-asserted-by":"crossref","first-page":"7132","DOI":"10.1021\/acs.chemrev.6b00562","article-title":"Biological activity of ionic liquids and their application in pharmaceutics and medicine","volume":"117","author":"Egorova","year":"2017","journal-title":"Chem. Rev."},{"key":"10.1016\/j.talanta.2018.03.001_bib12","doi-asserted-by":"crossref","first-page":"262","DOI":"10.1021\/ac4035554","article-title":"Ionic liquids in analytical chemistry: fundamentals, advances, and perspectives","volume":"86","author":"Ho","year":"2014","journal-title":"Anal. Chem."},{"key":"10.1016\/j.talanta.2018.03.001_bib13","doi-asserted-by":"crossref","first-page":"7597","DOI":"10.1007\/s00216-013-6950-x","article-title":"Bioanalytical separation and preconcentration using ionic liquids","volume":"405","author":"Escudero","year":"2013","journal-title":"Anal. Bioanal. Chem."},{"key":"10.1016\/j.talanta.2018.03.001_bib14","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1002\/jssc.201700864","article-title":"Ionic liquids: solvents and sorbents in sample preparation","volume":"41","author":"Clark","year":"2018","journal-title":"J. Sep. Sci."},{"key":"10.1016\/j.talanta.2018.03.001_bib15","doi-asserted-by":"crossref","first-page":"2027","DOI":"10.1007\/s00216-013-7467-z","article-title":"Recent developments in dispersive liquid-liquid microextraction","volume":"406","author":"Saraji","year":"2014","journal-title":"Anal. Bioanal. Chem."},{"key":"10.1016\/j.talanta.2018.03.001_bib16","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/j.trac.2013.06.008","article-title":"Ionic liquids in dispersive liquid-liquid microextraction","volume":"51","author":"Trujillo-Rodr\u00edguez","year":"2013","journal-title":"TrAC \u2013 Trends Anal. Chem."},{"key":"10.1016\/j.talanta.2018.03.001_bib17","doi-asserted-by":"crossref","first-page":"2268","DOI":"10.1016\/j.chroma.2009.09.011","article-title":"Extraction of organic compounds with room temperature ionic liquids","volume":"1217","author":"Poole","year":"2010","journal-title":"J. Chromatogr. A"},{"key":"10.1016\/j.talanta.2018.03.001_bib18","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1016\/j.trac.2014.08.018","article-title":"Green sample-preparation methods using room-temperature ionic liquids for the chromatographic analysis of organic compounds","volume":"71","author":"Poole","year":"2015","journal-title":"TrAC \u2013 Trends Anal. Chem."},{"key":"10.1016\/j.talanta.2018.03.001_bib19","doi-asserted-by":"crossref","DOI":"10.1016\/j.chroma.2017.10.019","article-title":"Applications of ionic liquids in biphasic separation: aqueous biphasic systems and liquid-liquid equilibria","author":"Shukla","year":"2018","journal-title":"J. Chromatogr. A"},{"key":"10.1016\/j.talanta.2018.03.001_bib20","doi-asserted-by":"crossref","first-page":"2444","DOI":"10.1002\/jssc.201600170","article-title":"Ionic-liquid-based dispersive liquid\u2013liquid microextraction coupled with high-performance liquid chromatography for the forensic determination of methamphetamine in human urine","volume":"39","author":"Wang","year":"2016","journal-title":"J. Sep. Sci."},{"key":"10.1016\/j.talanta.2018.03.001_bib21","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1007\/s10337-015-2850-x","article-title":"Analysis of methamphetamine in human urine using ionic liquid dispersive liquid-phase microextraction combined with HPLC","volume":"78","author":"Chen","year":"2015","journal-title":"Chromatographia"},{"key":"10.1016\/j.talanta.2018.03.001_bib22","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1016\/j.forsciint.2016.12.026","article-title":"Development and validation of a fast ionic liquid-based dispersive liquid-liquid microextraction procedure combined with LC-MS\/MS analysis for the quantification of benzodiazepines and benzodiazepine-like hypnotics in whole blood","volume":"274","author":"De Boeck","year":"2017","journal-title":"Forensic Sci. Int."},{"key":"10.1016\/j.talanta.2018.03.001_bib23","doi-asserted-by":"crossref","first-page":"292","DOI":"10.1016\/j.talanta.2017.12.044","article-title":"Fast and easy extraction of antidepressants from whole blood using ionic liquids as extraction solvent","volume":"180","author":"De Boeck","year":"2018","journal-title":"Talanta"},{"key":"10.1016\/j.talanta.2018.03.001_bib24","series-title":"Principles of Forensic Toxicology","author":"Levine","year":"2013"},{"key":"10.1016\/j.talanta.2018.03.001_bib25","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1016\/j.chroma.2012.06.023","article-title":"The evaluation of the applicability of a high pH mobile phase in ultrahigh performance liquid chromatography tandem mass spectrometry analysis of benzodiazepines and benzodiazepine-like hypnotics in urine and blood","volume":"1249","author":"Verplaetse","year":"2012","journal-title":"J. Chromatogr. A"},{"key":"10.1016\/j.talanta.2018.03.001_bib26","doi-asserted-by":"crossref","DOI":"10.1016\/j.chroma.2017.09.044","article-title":"Recent advances on ionic liquid uses in separation techniques","author":"Berthod","year":"2018","journal-title":"J. Chromatogr. A"},{"key":"10.1016\/j.talanta.2018.03.001_bib27","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1016\/j.jfluchem.2005.11.007","article-title":"Review of ionic liquids with fluorine-containing anions","volume":"127","author":"Xue","year":"2006","journal-title":"J. Fluor. Chem."},{"key":"10.1016\/j.talanta.2018.03.001_bib28","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1016\/j.jhazmat.2014.10.049","article-title":"Toxicity assessment of ionic liquids with Vibrio fischeri: an alternative fully automated methodology","volume":"284","author":"Costa","year":"2015","journal-title":"J. Hazard. Mater."},{"key":"10.1016\/j.talanta.2018.03.001_bib29","doi-asserted-by":"crossref","first-page":"12611","DOI":"10.1021\/acs.est.5b03123","article-title":"Environmental application, fate, effects, and concerns of ionic liquids: a review","volume":"49","author":"Amde","year":"2015","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.talanta.2018.03.001_bib30","doi-asserted-by":"crossref","unstructured":"M. Koel, C. Schr\u00f6der, General review of ionic liquids and their properties, in: Anal. Appl. Ion. Liq., World Scientific Publishing Europe Ltd., London, 2016.","DOI":"10.1142\/9781786340726_0001"},{"key":"10.1016\/j.talanta.2018.03.001_bib31","doi-asserted-by":"crossref","first-page":"e52323","DOI":"10.1371\/journal.pone.0052323","article-title":"A unified model of the GABAA receptor comprising agonist and benzodiazepine binding sites","volume":"8","author":"Bergmann","year":"2013","journal-title":"PLoS One"},{"key":"10.1016\/j.talanta.2018.03.001_bib32","doi-asserted-by":"crossref","first-page":"1685","DOI":"10.1021\/acs.jced.6b00077","article-title":"Comparison of ionic liquids to conventional organic solvents for extraction of aromatics from aliphatics","volume":"61","author":"Canales","year":"2016","journal-title":"J. Chem. Eng. Data."},{"key":"10.1016\/j.talanta.2018.03.001_bib33","doi-asserted-by":"crossref","first-page":"336","DOI":"10.1002\/cssc.201300459","article-title":"Toxicity of ionic liquids: Eco(cyto)activity as complicated, but unavoidable parameter for task-specific optimization","volume":"7","author":"Egorova","year":"2014","journal-title":"ChemSusChem"},{"key":"10.1016\/j.talanta.2018.03.001_bib34","doi-asserted-by":"crossref","first-page":"1474","DOI":"10.1021\/ac202661j","article-title":"Reduction of matrix effects in liquid chromatography-electrospray ionization-mass spectrometry by dilution of the sample extracts: How much dilution is needed?","volume":"84","author":"Stahnke","year":"2012","journal-title":"Anal. Chem."},{"key":"10.1016\/j.talanta.2018.03.001_bib35","first-page":"8","article-title":"Liquid chromatography tandem mass spectrometry in forensic toxicology: what about matrix effects?","volume":"41","author":"Verplaetse","year":"2011","journal-title":"TIAFT Bull."},{"key":"10.1016\/j.talanta.2018.03.001_bib36","doi-asserted-by":"crossref","first-page":"2155","DOI":"10.1007\/s00216-012-6035-2","article-title":"Aspects of matrix effects in applications of liquid chromatography-mass spectrometry to forensic and clinical toxicology-a review","volume":"403","author":"Peters","year":"2012","journal-title":"Anal. Bioanal. Chem."},{"key":"10.1016\/j.talanta.2018.03.001_bib37","doi-asserted-by":"crossref","first-page":"1122","DOI":"10.1021\/ar700053z","article-title":"Amino acid ionic liquids","volume":"40","author":"Ohno","year":"2007","journal-title":"Acc. Chem. Res."}],"container-title":["Talanta"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0039914018302339?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0039914018302339?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,22]],"date-time":"2025-09-22T12:18:43Z","timestamp":1758543523000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0039914018302339"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,7]]},"references-count":37,"alternative-id":["S0039914018302339"],"URL":"https:\/\/doi.org\/10.1016\/j.talanta.2018.03.001","relation":{},"ISSN":["0039-9140"],"issn-type":[{"value":"0039-9140","type":"print"}],"subject":[],"published":{"date-parts":[[2018,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Evaluation of 11 ionic liquids as potential extraction solvents for benzodiazepines from whole blood using liquid-liquid microextraction combined with LC-MS\/MS","name":"articletitle","label":"Article Title"},{"value":"Talanta","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.talanta.2018.03.001","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}