{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,14]],"date-time":"2026-07-14T04:37:04Z","timestamp":1784003824271,"version":"3.55.0"},"reference-count":33,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2018,12,1]],"date-time":"2018-12-01T00:00:00Z","timestamp":1543622400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2018,12,1]],"date-time":"2018-12-01T00:00:00Z","timestamp":1543622400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"name":"Ministry of High Education and Scientific Research"},{"name":"NanoFastResponse","award":["PRF2017-D4P1"],"award-info":[{"award-number":["PRF2017-D4P1"]}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Talanta"],"published-print":{"date-parts":[[2018,12]]},"DOI":"10.1016\/j.talanta.2018.07.087","type":"journal-article","created":{"date-parts":[[2018,7,27]],"date-time":"2018-07-27T12:25:32Z","timestamp":1532694332000},"page":"182-187","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":20,"special_numbering":"C","title":["Ultrasensitive sensing of Androctonus australis hector scorpion venom toxins in biological fluids using an electrochemical graphene quantum dots\/nanobody-based platform"],"prefix":"10.1016","volume":"190","author":[{"given":"Abdelmoneim","family":"Mars","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Balkiss","family":"Bouhaouala-Zahar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Noureddine","family":"Raouafi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.talanta.2018.07.087_bib1","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1016\/j.actatropica.2008.05.021","article-title":"Epidemiology of scorpionism: a global appraisal","volume":"107","author":"Chippaux","year":"2008","journal-title":"Acta Trop."},{"key":"10.1016\/j.talanta.2018.07.087_bib2","doi-asserted-by":"crossref","first-page":"1015","DOI":"10.1016\/0041-0101(94)90383-2","article-title":"Scorpionism and serotherapy in Mexico","volume":"32","author":"Dehesa-Davila","year":"1994","journal-title":"Toxicon"},{"key":"10.1016\/j.talanta.2018.07.087_bib3","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1016\/0041-0101(82)90240-9","article-title":"Epidemiological and clinical characteristics of the scorpion envenomation in Tunisia","volume":"20","author":"Goyffon","year":"1982","journal-title":"Toxicon"},{"key":"10.1016\/j.talanta.2018.07.087_bib4","doi-asserted-by":"crossref","first-page":"918","DOI":"10.1016\/j.toxicon.2008.09.004","article-title":"Epidemiological, clinical characteristics and outcome of severe scorpion envenomation in South Tunisia: Multivariate analysis of 951 cases","volume":"52","author":"Bouaziz","year":"2008","journal-title":"Toxicon"},{"key":"10.1016\/j.talanta.2018.07.087_bib5","doi-asserted-by":"crossref","first-page":"721","DOI":"10.1016\/0041-0101(87)90122-X","article-title":"A competitve radioimmunoassay using a monoclonal antibody to detect the factor X activator of Russell's viper venom","volume":"25","author":"Purittayakamee","year":"1987","journal-title":"Toxicon"},{"key":"10.1016\/j.talanta.2018.07.087_bib6","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1006\/biol.1998.0160","article-title":"Effect of some variables on the in vivo determination of scorpion and viper venom toxicities","volume":"26","author":"Krifi","year":"1998","journal-title":"Biologicals"},{"key":"10.1016\/j.talanta.2018.07.087_bib7","first-page":"297","article-title":"Application of ELISA for the quantification of Androctonus austalis hector venom in the envenomed serum of people and rats before and after immunotherapy","volume":"96","author":"Hammoudi-Truki","year":"2003","journal-title":"Bull. Soc. Pathol. Exot."},{"key":"10.1016\/j.talanta.2018.07.087_bib8","unstructured":"J. Echterbille, N. Gilles, R. Araoz, E. De Pauw, L. Quinton, Methodology to fish peptide ligands of nAChRs from Cone snail venoms by MALDI-TOF mass spectrometry, ORBI. (2016)."},{"key":"10.1016\/j.talanta.2018.07.087_bib9","doi-asserted-by":"crossref","first-page":"821","DOI":"10.1016\/S0956-5663(02)00075-1","article-title":"An ISFET-based immunosensor for the detection of \u03b2-Bungarotoxin","volume":"17","author":"Selvanayagam","year":"2002","journal-title":"Biosens. Bioelectron."},{"key":"10.1016\/j.talanta.2018.07.087_bib10","doi-asserted-by":"crossref","first-page":"6312","DOI":"10.1021\/nn501796r","article-title":"Deep Ultraviolet to near-infrared emission and photoresponse in layered N-doped graphene quantum dots","volume":"8","author":"Tang","year":"2014","journal-title":"ACS Nano."},{"key":"10.1016\/j.talanta.2018.07.087_bib11","doi-asserted-by":"crossref","first-page":"1561","DOI":"10.1021\/acsnano.5b00437","article-title":"Solution-processed graphene quantum dot deep-UV photodetectors","volume":"9","author":"Zhang","year":"2015","journal-title":"ACS Nano."},{"key":"10.1016\/j.talanta.2018.07.087_bib12","doi-asserted-by":"crossref","first-page":"776","DOI":"10.1002\/adma.201003819","article-title":"An electrochemical avenue to green-luminescent graphene quantum dots as potential electron-acceptors for photovoltaics","volume":"23","author":"Li","year":"2011","journal-title":"Adv Mater."},{"key":"10.1016\/j.talanta.2018.07.087_bib13","doi-asserted-by":"crossref","first-page":"4929","DOI":"10.1002\/adfm.201501250","article-title":"Carbon and graphene quantum dots for optoelectronic and energy devices: A review","volume":"25","author":"Li","year":"2015","journal-title":"Adv. Funct. Mater."},{"key":"10.1016\/j.talanta.2018.07.087_bib14","doi-asserted-by":"crossref","first-page":"9960","DOI":"10.1021\/ja2036749","article-title":"Luminescent graphene quantum dots for organic photovoltaic devices","volume":"133","author":"Gupta","year":"2011","journal-title":"J. Am. Chem. Soc."},{"key":"10.1016\/j.talanta.2018.07.087_bib15","doi-asserted-by":"crossref","first-page":"22378","DOI":"10.1039\/c2jm35305a","article-title":"An efficient and stable fluorescent graphene quantum dot-agar composite as a converting material in white light emitting diodes","volume":"22","author":"Luk","year":"2012","journal-title":"J. Mater. Chem."},{"key":"10.1016\/j.talanta.2018.07.087_bib16","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1038\/nature11253","article-title":"Gate-tuning of graphene plasmons revealed by infrared nano-imaging","volume":"487","author":"Fei","year":"2012","journal-title":"Nature"},{"key":"10.1016\/j.talanta.2018.07.087_bib17","doi-asserted-by":"crossref","first-page":"7806","DOI":"10.1021\/nn301888e","article-title":"Excitation of plasmonics waves in graphene by guided-mode resonances","volume":"6","author":"Gao","year":"2012","journal-title":"ACS. Nano."},{"key":"10.1016\/j.talanta.2018.07.087_bib18","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1016\/j.bios.2017.04.050","article-title":"A novel ECL biosensor for the detection of concanavalin A based on glucose functionalized NiCo2S4 nanoparticles-grown on carboxylic graphene as quenching probe","volume":"96","author":"Li","year":"2017","journal-title":"Biosens. Bioelectron."},{"key":"10.1016\/j.talanta.2018.07.087_bib19","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1016\/j.bios.2017.04.052","article-title":"Using reduced graphene oxide-Ca:CdSe nanocomposite to enhance photoelectrochemical activity of gold nanoparticles functionalized tungsten oxide for highly sensitive prostate specific antigen detection","volume":"96","author":"Wang","year":"2017","journal-title":"Biosens. Bioelectron."},{"key":"10.1016\/j.talanta.2018.07.087_bib20","doi-asserted-by":"crossref","first-page":"1020","DOI":"10.1016\/j.bios.2016.10.032","article-title":"A sensitive electrochemiluminescence immunosensor based on Ru(bpy)32+ in 3D CuNi oxalate as luminophores and graphene oxide\u2013polyethylenimine as released Ru(bpy)32+ initiator","volume":"89","author":"Li","year":"2017","journal-title":"Biosens. Bioelectron."},{"key":"10.1016\/j.talanta.2018.07.087_bib21","first-page":"1","article-title":"Effect of Electron Interaction on Statistics of Conductance Oscillations in Open Quantum Dots: Does the Dephasing Time Saturate?","volume":"99","author":"Sols","year":"2007","journal-title":"Phys. Rev. Lett."},{"key":"10.1016\/j.talanta.2018.07.087_bib22","first-page":"1","article-title":"Graphene surface plasmons at the near-infrared optical regime","volume":"4","author":"Zhang","year":"2014","journal-title":"Sci. Rep."},{"key":"10.1016\/j.talanta.2018.07.087_bib23","first-page":"914","article-title":"Experimental therapy of African trypanosomiasis with a nanobodyconjugated human trypanolytic factor","volume":"22","author":"Baral","year":"2006","journal-title":"Med. Sci."},{"key":"10.1016\/j.talanta.2018.07.087_bib24","doi-asserted-by":"crossref","first-page":"1256","DOI":"10.1074\/jbc.M307341200","article-title":"Efficient targeting of conserved cryptic epitopes of infectious agents by single domain antibodies","volume":"279","author":"Cortez-Retamozo","year":"2004","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.talanta.2018.07.087_bib25","doi-asserted-by":"crossref","first-page":"1267","DOI":"10.1021\/acssensors.7b00495","article-title":"Nanobody-based apolipoprotein E immunosensor for point-of-care testing","volume":"2","author":"Ren","year":"2017","journal-title":"ACS Sens."},{"key":"10.1016\/j.talanta.2018.07.087_bib26","doi-asserted-by":"crossref","first-page":"3479","DOI":"10.1096\/fj.09-148213","article-title":"A bispecific nanobody to provide full protection against lethal scorpion envenoming","volume":"24","author":"Hmila","year":"2010","journal-title":"FASEB J."},{"key":"10.1016\/j.talanta.2018.07.087_bib27","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1016\/j.snb.2014.05.054","article-title":"Novel electrochemical sensor based on graphene quantum dots\/riboflavin nanocomposite for the detection of persulfate","volume":"201","author":"Roushani","year":"2014","journal-title":"Sensor. Actuat. B-Chem."},{"key":"10.1016\/j.talanta.2018.07.087_bib28","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1039\/an9962100345","article-title":"Electrochemical activation of screen-printed carbon strips","volume":"121","author":"Wang","year":"1996","journal-title":"Analyst"},{"key":"10.1016\/j.talanta.2018.07.087_bib29","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1016\/j.bios.2016.12.033","article-title":"Competitive RNA-RNA hybridization-based integrated nanostructured-disposable electrode for highly sensitive determination of miRNAs in cancer cells","volume":"91","author":"Zouari","year":"2017","journal-title":"Biosens. Bioelectron."},{"key":"10.1016\/j.talanta.2018.07.087_bib30","doi-asserted-by":"crossref","first-page":"2712","DOI":"10.1016\/j.bios.2008.12.010","article-title":"Easy modification of glassy carbon electrode for simultaneous determination of ascorbic acid, dopamine and uric acid","volume":"24","author":"Thiagarajan","year":"2009","journal-title":"Biosens. Bioelectron."},{"key":"10.1016\/j.talanta.2018.07.087_bib31","doi-asserted-by":"crossref","first-page":"1649","DOI":"10.1016\/0041-0101(94)90323-9","article-title":"ELISA for the detection of toxic antigens in experimental and clinical envenoming by Tityus serrulatus scorpion venom","volume":"32","author":"Chavez-Olortegui","year":"1994","journal-title":"Toxicon"},{"key":"10.1016\/j.talanta.2018.07.087_bib32","doi-asserted-by":"crossref","first-page":"246","DOI":"10.1006\/abio.2000.4942","article-title":"A fluorimetric method based on changes in membrane potential for screening paralytic shellfish toxins in mussels","volume":"289","author":"Louzao","year":"2001","journal-title":"Anal. Biochem."},{"key":"10.1016\/j.talanta.2018.07.087_bib33","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1016\/j.aca.2006.03.013","article-title":"Analysis of palytoxin-like in ostreopsis cultures by liquid chromatography with precolumn derivatization and fluorescence detection","volume":"566","author":"Riobo","year":"2006","journal-title":"Anal. Chim. Acta."}],"container-title":["Talanta"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0039914018307951?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0039914018307951?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,22]],"date-time":"2025-09-22T12:19:30Z","timestamp":1758543570000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0039914018307951"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,12]]},"references-count":33,"alternative-id":["S0039914018307951"],"URL":"https:\/\/doi.org\/10.1016\/j.talanta.2018.07.087","relation":{},"ISSN":["0039-9140"],"issn-type":[{"value":"0039-9140","type":"print"}],"subject":[],"published":{"date-parts":[[2018,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Ultrasensitive sensing of Androctonus australis hector scorpion venom toxins in biological fluids using an electrochemical graphene quantum dots\/nanobody-based platform","name":"articletitle","label":"Article Title"},{"value":"Talanta","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.talanta.2018.07.087","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}