{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T02:42:14Z","timestamp":1788316934998,"version":"build-2803163510"},"reference-count":25,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2021,11,1]],"date-time":"2021-11-01T00:00:00Z","timestamp":1635724800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,11,1]],"date-time":"2021-11-01T00:00:00Z","timestamp":1635724800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,6,24]],"date-time":"2021-06-24T00:00:00Z","timestamp":1624492800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100000780","name":"European Commission","doi-asserted-by":"publisher","award":["PID2019-106201RB-I00"],"award-info":[{"award-number":["PID2019-106201RB-I00"]}],"id":[{"id":"10.13039\/501100000780","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100021713","name":"Universidad de Almer\u00eda","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100021713","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002924","name":"Federaci\u00f3n Espa\u00f1ola de Enfermedades Raras","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002924","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100014853","name":"Cajamar Caja Rural","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100014853","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004837","name":"Ministerio de Ciencia e Innovaci\u00f3n","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004837","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100014440","name":"Spain Ministry of Science Innovation and Universities","doi-asserted-by":"publisher","award":["PID2019-106201RB-I00"],"award-info":[{"award-number":["PID2019-106201RB-I00"]}],"id":[{"id":"10.13039\/100014440","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100014440","name":"Spain Ministry of Science Innovation and Universities","doi-asserted-by":"publisher","award":["FPU19\/04260"],"award-info":[{"award-number":["FPU19\/04260"]}],"id":[{"id":"10.13039\/100014440","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Talanta"],"published-print":{"date-parts":[[2021,11]]},"DOI":"10.1016\/j.talanta.2021.122641","type":"journal-article","created":{"date-parts":[[2021,6,24]],"date-time":"2021-06-24T19:07:10Z","timestamp":1624561630000},"page":"122641","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":20,"special_numbering":"C","title":["Co-formulants in plant protection products: An analytical approach to their determination by gas chromatography\u2013high resolution mass accuracy spectrometry"],"prefix":"10.1016","volume":"234","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8457-6597","authenticated-orcid":false,"given":"Antonio Jes\u00fas","family":"Maldonado-Reina","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0806-9013","authenticated-orcid":false,"given":"Rosal\u00eda","family":"L\u00f3pez-Ruiz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7904-7842","authenticated-orcid":false,"given":"Antonia","family":"Garrido Frenich","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0760-6008","authenticated-orcid":false,"given":"F. Javier","family":"Arrebola","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2505-2056","authenticated-orcid":false,"given":"Roberto","family":"Romero-Gonz\u00e1lez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.talanta.2021.122641_bib1","series-title":"Protection agency (EPA), U.S. Code of federal regulations. Title 40 protection of environment","year":"2008"},{"key":"10.1016\/j.talanta.2021.122641_bib2","first-page":"686","article-title":"Role of pesticide formulations for sustainable crop protection and environment management: a review","volume":"8","author":"Hazra","year":"2019","journal-title":"J. Pharmacogn. Phytochem."},{"key":"10.1016\/j.talanta.2021.122641_bib3","series-title":"Application of Nanoemulsions in Formulation of Pesticides","author":"Feng","year":"2018"},{"key":"10.1016\/j.talanta.2021.122641_bib4","first-page":"232","article-title":"Recent advances in pesticide formulations for eco-friendly and sustainable vegetable pest management: a review","volume":"2","author":"Hazra","year":"2017","journal-title":"Arch. Agric. Environ. Sci."},{"key":"10.1016\/j.talanta.2021.122641_bib5","series-title":"Influence of Adjuvants and Formulations on the Emission of Pesticides to the Atmosphere","author":"De Ruiter","year":"2003"},{"key":"10.1016\/j.talanta.2021.122641_bib6","series-title":"Fundam. Weed Sci.","first-page":"501","article-title":"Herbicide formulation","author":"Zimdahl","year":"2018"},{"key":"10.1016\/j.talanta.2021.122641_bib7","year":"2020"},{"key":"10.1016\/j.talanta.2021.122641_bib8","doi-asserted-by":"crossref","first-page":"1535","DOI":"10.1007\/s00216-009-2633-z","article-title":"Determination of metalaxyl and identification of adjuvants in wettable powder pesticide technical formulas","volume":"394","author":"Pose-Juan","year":"2009","journal-title":"Anal. Bioanal. Chem."},{"key":"10.1016\/j.talanta.2021.122641_bib9","doi-asserted-by":"crossref","first-page":"2404","DOI":"10.1016\/j.atmosenv.2011.02.015","article-title":"Volatile organic compounds in pesticide formulations: methods to estimate ozone formation potential","volume":"45","author":"Zeinali","year":"2011","journal-title":"Atmos. Environ."},{"key":"10.1016\/j.talanta.2021.122641_bib10","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1016\/j.chroma.2013.10.032","article-title":"Characterization of polyoxyethylene tallow amine surfactants in technical mixtures and glyphosate formulations using ultra-high performance liquid chromatography and triple quadrupole mass spectrometry","volume":"1319","author":"Tush","year":"2013","journal-title":"J. Chromatogr. A"},{"key":"10.1016\/j.talanta.2021.122641_bib11","series-title":"No 547\/2011 of 8 June 2011 Implementing Regulation (EC) No 1107\/2009 of the European Parliament and of the Council as Regards Labelling Requirements for Plant Protection Products","year":"2011"},{"key":"10.1016\/j.talanta.2021.122641_bib12","series-title":"No 540\/2011 of 25 May 2011 Implementing Regulation (EC) No 1107\/2009 of the European Parliament and of the Council as Regards the List of Approved Active Substances","year":"2011"},{"key":"10.1016\/j.talanta.2021.122641_bib13","series-title":"2021\/383 of 3 March 2021 Amending Annex III to Regulation (EC) No 1107\/2009 of the European Parliament and of the Council Listing Co-formulants Which Are Not Accepted for Inclusion in Plant Protection Products","year":"2021"},{"key":"10.1016\/j.talanta.2021.122641_bib14","series-title":"Oil in Water Nanoemulsion Formulations of Botanical Active Substances","author":"Pascual-Villalobos","year":"2019"},{"key":"10.1016\/j.talanta.2021.122641_bib15","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1080\/08958378.2018.1430190","article-title":"Comparative inhalation toxicity of ethyltoluene isomers in rats and mice","volume":"29","author":"Roberts","year":"2017","journal-title":"Inhal. Toxicol."},{"key":"10.1016\/j.talanta.2021.122641_bib16","doi-asserted-by":"crossref","first-page":"736","DOI":"10.1080\/03601234.2016.1198637","article-title":"Simultaneous gas chromatographic determination of chlorpyrifos and its impurity sulfotep in liquid pesticide formulations","volume":"51","author":"P\u0142onka","year":"2016","journal-title":"J. Environ. Sci. Health Part B Pestic. Food Contam. Agric. Wastes"},{"key":"10.1016\/j.talanta.2021.122641_bib17","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1155\/2013\/121783","article-title":"Simultaneous determination of benzene and toluene in pesticide emulsifiable concentrate by headspace GC-MS","volume":"2013","author":"Cao","year":"2013","journal-title":"J. Anal. Methods Chem."},{"key":"10.1016\/j.talanta.2021.122641_bib18","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/j.trac.2016.03.011","article-title":"Chromatographic methods for the determination of active substances and characterization of their impurities in pesticide formulations","volume":"85","author":"P\u0142onka","year":"2016","journal-title":"Trends Anal. Chem."},{"key":"10.1016\/j.talanta.2021.122641_bib19","doi-asserted-by":"crossref","DOI":"10.1007\/s00216-020-02662-0","article-title":"Identification of adjuvants in plant protection products applying a suspect screening workflow based on orthogonal techniques","author":"L\u00f3pez-Ruiz","year":"2020","journal-title":"Anal. Bioanal. Chem."},{"key":"10.1016\/j.talanta.2021.122641_bib20","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1093\/jat\/bkr014","article-title":"Two suicidal fatalities due to the ingestion of chlorfenvinphos formulations: simultaneous determination of the pesticide and the petroleum distillates in tissues by gas chromatography-flame-ionization detection and gas chromatography- mass spectrometry","volume":"36","author":"Mart\u00ednez","year":"2012","journal-title":"J. Anal. Toxicol."},{"key":"10.1016\/j.talanta.2021.122641_bib21","doi-asserted-by":"crossref","first-page":"63","DOI":"10.5271\/sjweh.1502","article-title":"Solvents in pesticides","volume":"19","author":"Petrelli","year":"1993","journal-title":"Scand. J. Work. Environ. Health"},{"key":"10.1016\/j.talanta.2021.122641_bib22","series-title":"Analytical Quality Control and Method Validation for Pesticide Residues Analysis in Food and Feed (SANTE\/12682\/2019), Sante\/12682\/2019","first-page":"1","year":"2019"},{"key":"10.1016\/j.talanta.2021.122641_bib23","series-title":"Reference Dose (RfD): description and use in health risk assessments background document 1A","year":"1993"},{"key":"10.1016\/j.talanta.2021.122641_bib24","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1016\/j.yrtph.2005.05.004","article-title":"The no-observed-adverse-effect-level in drug safety evaluations: use, issues, and definition(s)","volume":"42","author":"Dorato","year":"2005","journal-title":"Regul. Toxicol. Pharmacol."},{"key":"10.1016\/j.talanta.2021.122641_bib25","doi-asserted-by":"crossref","first-page":"108926","DOI":"10.1016\/j.envres.2019.108926","article-title":"Systematic review of comparative studies assessing the toxicity of pesticide active ingredients and their product formulations","volume":"181","author":"Nagy","year":"2020","journal-title":"Environ. Res."}],"container-title":["Talanta"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0039914021005622?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0039914021005622?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T06:48:08Z","timestamp":1777445288000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0039914021005622"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,11]]},"references-count":25,"alternative-id":["S0039914021005622"],"URL":"https:\/\/doi.org\/10.1016\/j.talanta.2021.122641","relation":{},"ISSN":["0039-9140"],"issn-type":[{"value":"0039-9140","type":"print"}],"subject":[],"published":{"date-parts":[[2021,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Co-formulants in plant protection products: An analytical approach to their determination by gas chromatography\u2013high resolution mass accuracy spectrometry","name":"articletitle","label":"Article Title"},{"value":"Talanta","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.talanta.2021.122641","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 The Authors. Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"122641"}}