{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,13]],"date-time":"2026-05-13T08:14:38Z","timestamp":1778660078941,"version":"3.51.4"},"reference-count":37,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2022,5,1]],"date-time":"2022-05-01T00:00:00Z","timestamp":1651363200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,5,1]],"date-time":"2022-05-01T00:00:00Z","timestamp":1651363200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,5,1]],"date-time":"2022-05-01T00:00:00Z","timestamp":1651363200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2022,5,1]],"date-time":"2022-05-01T00:00:00Z","timestamp":1651363200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2022,5,1]],"date-time":"2022-05-01T00:00:00Z","timestamp":1651363200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2022,5,1]],"date-time":"2022-05-01T00:00:00Z","timestamp":1651363200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2022,5,1]],"date-time":"2022-05-01T00:00:00Z","timestamp":1651363200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100011645","name":"Kaohsiung Medical University Chung-Ho Memorial Hospital","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100011645","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004663","name":"Ministry of Science and Technology, Taiwan","doi-asserted-by":"publisher","award":["MOST 108-2113-M-037-018-MY2"],"award-info":[{"award-number":["MOST 108-2113-M-037-018-MY2"]}],"id":[{"id":"10.13039\/501100004663","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004663","name":"Ministry of Science and Technology, Taiwan","doi-asserted-by":"publisher","award":["MOST 105-2113-M-037-012-MY3"],"award-info":[{"award-number":["MOST 105-2113-M-037-012-MY3"]}],"id":[{"id":"10.13039\/501100004663","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Talanta"],"published-print":{"date-parts":[[2022,5]]},"DOI":"10.1016\/j.talanta.2021.123199","type":"journal-article","created":{"date-parts":[[2022,1,1]],"date-time":"2022-01-01T10:32:36Z","timestamp":1641033156000},"page":"123199","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":5,"special_numbering":"C","title":["Identifiable universal fluorescent multiplex PCR equipped with capillary electrophoresis for genotyping of exons 1 to 5 in human red and green pigment genes"],"prefix":"10.1016","volume":"241","author":[{"given":"Tzu-Yu","family":"Pan","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hwang-Shang","family":"Kou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shou-Mei","family":"Wu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3546-9576","authenticated-orcid":false,"given":"Chun-Chi","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"5","key":"10.1016\/j.talanta.2021.123199_bib1","doi-asserted-by":"crossref","first-page":"691","DOI":"10.1001\/archopht.118.5.691","article-title":"Molecular genetics of color vision and color vision defects","volume":"118","author":"Neitz","year":"2000","journal-title":"Arch. Ophthalmol."},{"issue":"4","key":"10.1016\/j.talanta.2021.123199_bib2","doi-asserted-by":"crossref","first-page":"1697","DOI":"10.1093\/genetics\/158.4.1697","article-title":"The molecular genetics and evolution of red and green color vision in vertebrates","volume":"158","author":"Yokoyama","year":"2001","journal-title":"Genetics"},{"issue":"3","key":"10.1016\/j.talanta.2021.123199_bib3","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1017\/S0952523804213244","article-title":"Molecular genetics of color-vision deficiencies","volume":"21","author":"Deeb","year":"2004","journal-title":"Vis. Neurosci."},{"issue":"2","key":"10.1016\/j.talanta.2021.123199_bib4","doi-asserted-by":"crossref","first-page":"919","DOI":"10.1093\/genetics\/153.2.919","article-title":"The molecular genetics of red and green color vision in mammals","volume":"153","author":"Yokoyama","year":"1999","journal-title":"Genetics"},{"issue":"3","key":"10.1016\/j.talanta.2021.123199_bib5","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1016\/j.gde.2006.04.002","article-title":"Genetics of variation in human color vision and the retinal cone mosaic","volume":"16","author":"Deeb","year":"2006","journal-title":"Curr. Opin. Genet. Dev."},{"issue":"8","key":"10.1016\/j.talanta.2021.123199_bib6","doi-asserted-by":"crossref","first-page":"686","DOI":"10.1007\/s10038-006-0008-2","article-title":"Protan color vision deficiency with a unique order of green\u2013red as the first two genes of a visual pigment array","volume":"51","author":"Ueyama","year":"2006","journal-title":"J. Hum. Genet."},{"issue":"3","key":"10.1016\/j.talanta.2021.123199_bib7","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1093\/jb\/mvv034","article-title":"A new subset of deutan colour vision defect associated with an L\/M visual pigment gene array of normal order and\u2212 71C substitution in the Japanese population","volume":"158","author":"Ueyama","year":"2015","journal-title":"J. Biochem."},{"issue":"9","key":"10.1016\/j.talanta.2021.123199_bib8","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1038\/jhg.2009.73","article-title":"Analysis of introns and promoters of L\/M visual pigment genes in relation to deutan color-vision deficiency with an array of normal gene orders","volume":"54","author":"Ueyama","year":"2009","journal-title":"J. Hum. Genet."},{"issue":"8","key":"10.1016\/j.talanta.2021.123199_bib9","doi-asserted-by":"crossref","DOI":"10.1167\/10.8.12","article-title":"The dimensionality of color vision in carriers of anomalous trichromacy","volume":"10","author":"Jordan","year":"2010","journal-title":"J. Vis."},{"key":"10.1016\/j.talanta.2021.123199_bib10","series-title":"Diagnosis of Defective Colour Vision","author":"Birch","year":"2001"},{"issue":"2","key":"10.1016\/j.talanta.2021.123199_bib11","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1111\/j.1444-0938.2006.00015.x","article-title":"The new Richmond HRR pseudoisochromatic test for colour vision is better than the Ishihara test","volume":"89","author":"Cole","year":"2006","journal-title":"Clin. Exp. Optom."},{"issue":"4\u20135","key":"10.1016\/j.talanta.2021.123199_bib12","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1111\/j.1444-0938.2004.tb05057.x","article-title":"Clinical colour vision tests","volume":"87","author":"Dain","year":"2004","journal-title":"Clin. Exp. Optom."},{"issue":"2","key":"10.1016\/j.talanta.2021.123199_bib13","first-page":"7","article-title":"The evolution of colour vision testing","volume":"40","author":"French","year":"2008","journal-title":"Austral. Orthoptic J."},{"issue":"1","key":"10.1016\/j.talanta.2021.123199_bib14","first-page":"25","article-title":"Review of the main colour vision clinical assessment tests","volume":"94","author":"Zarazaga","year":"2019","journal-title":"Arch. Soc. Esp. Oftalmol."},{"issue":"23","key":"10.1016\/j.talanta.2021.123199_bib15","doi-asserted-by":"crossref","first-page":"10053","DOI":"10.1523\/JNEUROSCI.18-23-10053.1998","article-title":"Red, green, and red-green hybrid pigments in the human retina: correlations between deduced protein sequences and psychophysically measured spectral sensitivities","volume":"18","author":"Sharpe","year":"1998","journal-title":"J. Neurosci."},{"issue":"4","key":"10.1016\/j.talanta.2021.123199_bib16","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1007\/s00417-005-0086-4","article-title":"Visual acuity and X-linked color blindness","volume":"244","author":"J\u00e4gle","year":"2006","journal-title":"Graefes Arch. Clin. Exp. Ophthalmol."},{"key":"10.1016\/j.talanta.2021.123199_bib17","series-title":"Molecular Genetics and Evolution of Red-Green Vision in Vertebrates","author":"Radlwimmer","year":"2002"},{"issue":"1","key":"10.1016\/j.talanta.2021.123199_bib18","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1016\/S0021-5155(00)00298-7","article-title":"Number and variations of the red and green visual pigment genes in Japanese men with normal color vision","volume":"45","author":"Hayashi","year":"2001","journal-title":"Jpn. J. Ophthalmol."},{"issue":"4","key":"10.1016\/j.talanta.2021.123199_bib19","doi-asserted-by":"crossref","first-page":"767","DOI":"10.1076\/ceyr.21.4.767.5544","article-title":"Detection of female carriers of congenital color-vision deficiencies by visual pigment gene analysis","volume":"21","author":"Oda","year":"2000","journal-title":"Curr. Eye Res."},{"key":"10.1016\/j.talanta.2021.123199_bib20","doi-asserted-by":"crossref","first-page":"651","DOI":"10.1016\/S0076-6879(00)16755-2","article-title":"[43] Molecular analysis of human red\/green visual pigment gene locus: relationship to color vision","volume":"316","author":"Deeb","year":"2000","journal-title":"Methods Enzymol."},{"issue":"19","key":"10.1016\/j.talanta.2021.123199_bib21","doi-asserted-by":"crossref","first-page":"2241","DOI":"10.1016\/j.visres.2004.04.011","article-title":"Analysis of L-cone\/M-cone visual pigment gene arrays in Japanese males with protan color-vision deficiency","volume":"44","author":"Ueyama","year":"2004","journal-title":"Vis. Res."},{"key":"10.1016\/j.talanta.2021.123199_bib22","article-title":"Long-range polymerase chain reaction analysis for specifying photopigment opsin gene polymorphisms","volume":"9","author":"Wasserman","year":"2009","journal-title":"Tech. Rep. Ser. # MBS"},{"issue":"10","key":"10.1016\/j.talanta.2021.123199_bib23","doi-asserted-by":"crossref","first-page":"3627","DOI":"10.1128\/JCM.00488-11","article-title":"Rapid and accurate identification of human-associated staphylococci by use of multiplex PCR","volume":"49","author":"Hirotaki","year":"2011","journal-title":"J. Clin. Microbiol."},{"issue":"8","key":"10.1016\/j.talanta.2021.123199_bib24","doi-asserted-by":"crossref","first-page":"982","DOI":"10.3390\/foods9080982","article-title":"Species identification of red deer (Cervus elaphus), roe deer (Capreolus capreolus), and water deer (hydropotes inermis) using capillary electrophoresis-based multiplex PCR","volume":"9","author":"Kim","year":"2020","journal-title":"Foods"},{"key":"10.1016\/j.talanta.2021.123199_bib25","doi-asserted-by":"crossref","first-page":"126451","DOI":"10.1016\/j.foodchem.2020.126451","article-title":"A multiplex PCR assay combined with capillary electrophoresis for the simultaneous detection of tropomyosin allergens from oyster, mussel, abalone, and clam mollusk species","volume":"317","author":"Suh","year":"2020","journal-title":"Food Chem."},{"issue":"6071","key":"10.1016\/j.talanta.2021.123199_bib26","doi-asserted-by":"crossref","first-page":"674","DOI":"10.1038\/321674a0","article-title":"Fluorescence detection in automated DNA sequence analysis","volume":"321","author":"Smith","year":"1986","journal-title":"Nature"},{"issue":"2","key":"10.1016\/j.talanta.2021.123199_bib27","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1038\/72708","article-title":"An economic method for the fluorescent labeling of PCR fragments","volume":"18","author":"Schuelke","year":"2000","journal-title":"Nat. Biotechnol."},{"key":"10.1016\/j.talanta.2021.123199_bib28","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1016\/j.aca.2014.05.008","article-title":"Universal fluorescent tri-probe ligation equipped with capillary electrophoresis for targeting SMN1 and SMN2 genes in diagnosis of spinal muscular atrophy","volume":"833","author":"Wang","year":"2014","journal-title":"Anal. Chim. Acta"},{"issue":"11","key":"10.1016\/j.talanta.2021.123199_bib29","doi-asserted-by":"crossref","first-page":"1600","DOI":"10.1002\/elps.201900052","article-title":"A multiplex SNP genotyping by allele\u2010specificspecific PCR based on stem\u2010loop and universal fluorescent primers of Chr1daxin mice","volume":"40","author":"Wang","year":"2019","journal-title":"Electrophoresis"},{"key":"10.1016\/j.talanta.2021.123199_bib30","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1016\/j.gene.2017.06.014","article-title":"Rapid prenatal diagnosis of aneuploidy for chromosomes 21, 18, 13, X, and Y using segmental duplication quantitative fluorescent PCR (SD-QF-PCR)","volume":"627","author":"Sun","year":"2017","journal-title":"Gene"},{"issue":"14","key":"10.1016\/j.talanta.2021.123199_bib31","doi-asserted-by":"crossref","first-page":"2396","DOI":"10.1002\/elps.201000124","article-title":"Multi\u2010exon genotyping of SMN gene in spinal muscular atrophy by universal fluorescent PCR and capillary electrophoresis","volume":"31","author":"Wang","year":"2010","journal-title":"Electrophoresis"},{"issue":"4","key":"10.1016\/j.talanta.2021.123199_bib32","doi-asserted-by":"crossref","first-page":"272","DOI":"10.1136\/jmg.37.4.272","article-title":"Universal primer quantitative fluorescent multiplex (UPQFM) PCR: a method to detect major and minor rearrangements of the low density lipoprotein receptor gene","volume":"37","author":"Heath","year":"2000","journal-title":"J. Med. Genet."},{"issue":"2","key":"10.1016\/j.talanta.2021.123199_bib33","first-page":"149","article-title":"Linkage of color blindness to hemophilias A and B","volume":"14","author":"Whittaker","year":"1962","journal-title":"Am. J. Hum. Genet."},{"issue":"1","key":"10.1016\/j.talanta.2021.123199_bib34","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1111\/j.1469-1809.1986.tb01935.x","article-title":"The linkage between the genes for colour-blindness and haemophilia in man. By Julia Bell and JBS Haldane","volume":"50","author":"Bell","year":"1986","journal-title":"1937, Ann. Hum. Genetics"},{"issue":"2","key":"10.1016\/j.talanta.2021.123199_bib35","first-page":"53","article-title":"Evaluation of salt-out method for the isolation of DNA from whole blood: a pathological approach of DNA based diagnosis","volume":"2","author":"Maurya","year":"2013","journal-title":"Int. J. Life Sci. Biotechnol. Pharma Res."},{"issue":"13","key":"10.1016\/j.talanta.2021.123199_bib36","doi-asserted-by":"crossref","first-page":"2904","DOI":"10.1002\/elps.200700799","article-title":"Quantification of SMN1 and SMN2 genes by capillary electrophoresis for diagnosis of spinal muscular atrophy","volume":"29","author":"Wang","year":"2008","journal-title":"Electrophoresis"},{"issue":"23","key":"10.1016\/j.talanta.2021.123199_bib37","doi-asserted-by":"crossref","first-page":"3387","DOI":"10.1002\/elps.201400172","article-title":"Genotyping of exons 1 to 20 in Duchenne muscular dystrophy by universal multiplex PCR and short\u2010end capillary electrophoresis","volume":"35","author":"Syu","year":"2014","journal-title":"Electrophoresis"}],"container-title":["Talanta"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0039914021011218?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0039914021011218?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,5,13]],"date-time":"2026-05-13T07:56:45Z","timestamp":1778659005000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0039914021011218"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,5]]},"references-count":37,"alternative-id":["S0039914021011218"],"URL":"https:\/\/doi.org\/10.1016\/j.talanta.2021.123199","relation":{},"ISSN":["0039-9140"],"issn-type":[{"value":"0039-9140","type":"print"}],"subject":[],"published":{"date-parts":[[2022,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Identifiable universal fluorescent multiplex PCR equipped with capillary electrophoresis for genotyping of exons 1 to 5 in human red and green pigment genes","name":"articletitle","label":"Article Title"},{"value":"Talanta","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.talanta.2021.123199","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"123199"}}