{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,19]],"date-time":"2026-09-19T14:00:02Z","timestamp":1789826402215,"version":"4.0.1"},"reference-count":25,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2023,6,1]],"date-time":"2023-06-01T00:00:00Z","timestamp":1685577600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,6,1]],"date-time":"2023-06-01T00:00:00Z","timestamp":1685577600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,6,1]],"date-time":"2023-06-01T00:00:00Z","timestamp":1685577600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2023,6,1]],"date-time":"2023-06-01T00:00:00Z","timestamp":1685577600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2023,6,1]],"date-time":"2023-06-01T00:00:00Z","timestamp":1685577600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2023,6,1]],"date-time":"2023-06-01T00:00:00Z","timestamp":1685577600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2023,6,1]],"date-time":"2023-06-01T00:00:00Z","timestamp":1685577600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["21874157"],"award-info":[{"award-number":["21874157"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["21675175"],"award-info":[{"award-number":["21675175"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["22074160"],"award-info":[{"award-number":["22074160"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012476","name":"Fundamental Research Funds for Central Universities of the Central South University","doi-asserted-by":"publisher","award":["CZZ22003"],"award-info":[{"award-number":["CZZ22003"]}],"id":[{"id":"10.13039\/501100012476","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Talanta"],"published-print":{"date-parts":[[2023,6]]},"DOI":"10.1016\/j.talanta.2023.124377","type":"journal-article","created":{"date-parts":[[2023,2,17]],"date-time":"2023-02-17T20:21:25Z","timestamp":1676665285000},"page":"124377","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":41,"special_numbering":"C","title":["A high performance dual-mode biosensor based on Nd-MOF nanosheets functionalized with ionic liquid and gold nanoparticles for sensing of ctDNA"],"prefix":"10.1016","volume":"258","author":[{"given":"Ruyan","family":"Zha","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruoyu","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuange","family":"Zong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhengguo","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tsunghsueh","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yingying","family":"Zhong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haiping","family":"Liang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lifei","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chunya","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yanying","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.talanta.2023.124377_bib1","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-020-71236-y","article-title":"Prognostic and predictive value of circulating tumor DNA during neoadjuvant chemotherapy for triple negative breast cancer","volume":"10","author":"Cavallone","year":"2020","journal-title":"Sci. Rep."},{"key":"10.1016\/j.talanta.2023.124377_bib2","doi-asserted-by":"crossref","DOI":"10.1016\/j.critrevonc.2020.103109","article-title":"ctDNA as a cancer biomarker: a broad overview","volume":"155","author":"Pessoa","year":"2020","journal-title":"Crit. Rev. Oncol. Hematol."},{"key":"10.1016\/j.talanta.2023.124377_bib3","doi-asserted-by":"crossref","first-page":"691","DOI":"10.1373\/clinchem.2016.262337","article-title":"Patient -specific circulating tumor DNA detection during neoadjuvant chemotherapy in triple -negative breast cancer","volume":"63","author":"Riva","year":"2017","journal-title":"Clin. Chem."},{"key":"10.1016\/j.talanta.2023.124377_bib4","doi-asserted-by":"crossref","DOI":"10.1016\/j.snb.2022.131807","article-title":"Electrochemical detection of ctDNA mutation in non-small cell lung cancer based on CRISPR\/Cas12a system","volume":"362","author":"Liu","year":"2022","journal-title":"Sensor. Actuator. B Chem."},{"key":"10.1016\/j.talanta.2023.124377_bib5","doi-asserted-by":"crossref","DOI":"10.1016\/j.bios.2022.114508","article-title":"An ultrasensitive dual-signal aptasensor based on functionalized Sb@ZIF-67 nanocomposites for simultaneously detect multiple biomarkers","volume":"214","author":"Zhang","year":"2022","journal-title":"Biosens. Bioelectron."},{"key":"10.1016\/j.talanta.2023.124377_bib6","doi-asserted-by":"crossref","DOI":"10.1016\/j.trac.2019.115795","article-title":"Design strategies of AuNPs-based nucleic acid colorimetric biosensors","volume":"124","author":"Yang","year":"2020","journal-title":"Trends Anal. Chem."},{"key":"10.1016\/j.talanta.2023.124377_bib7","doi-asserted-by":"crossref","DOI":"10.1016\/j.snb.2020.128764","article-title":"A label-free DNA-based fluorescent sensor for cisplatin detection","volume":"326","author":"Jantarat","year":"2021","journal-title":"Sensor. Actuator. B Chem."},{"key":"10.1016\/j.talanta.2023.124377_bib8","doi-asserted-by":"crossref","first-page":"14178","DOI":"10.1021\/acs.analchem.1c02881","article-title":"Zinc\u2013metal organic frameworks: a coreactant-free electrochemiluminescence luminophore for ratiometric detection of miRNA-133a","volume":"93","author":"Wang","year":"2021","journal-title":"Anal. Chem."},{"key":"10.1016\/j.talanta.2023.124377_bib9","doi-asserted-by":"crossref","DOI":"10.1016\/j.bios.2019.111826","article-title":"Target-driven rolling walker based electrochemical biosensor for ultrasensitive detection of circulating tumor DNA using doxorubicin@tetrahedron-Au tags","volume":"148","author":"Li","year":"2020","journal-title":"Biosens. Bioelectron."},{"key":"10.1016\/j.talanta.2023.124377_bib10","doi-asserted-by":"crossref","first-page":"31178","DOI":"10.1021\/acsami.8b12286","article-title":"Enhancing the photoelectrochemical response of DNA biosensors using wrinkled interfaces","volume":"10","author":"Saha","year":"2018","journal-title":"ACS Appl. Mater. Interfaces"},{"key":"10.1016\/j.talanta.2023.124377_bib11","doi-asserted-by":"crossref","first-page":"8364","DOI":"10.1021\/acs.analchem.0c00918","article-title":"In situ formation of multifunctional DNA nanospheres for a sensitive and accurate dual-mode biosensor for photoelectrochemical and electrochemical assay","volume":"92","author":"Deng","year":"2020","journal-title":"Anal. Chem."},{"key":"10.1016\/j.talanta.2023.124377_bib12","doi-asserted-by":"crossref","first-page":"14272","DOI":"10.1021\/acs.analchem.1c03354","article-title":"Highly selective and sensitive microRNA-210 assay based on dual-signaling electrochemical and photocurrent-polarity-switching strategies","volume":"93","author":"Zhang","year":"2021","journal-title":"Anal. Chem."},{"key":"10.1016\/j.talanta.2023.124377_bib13","first-page":"1280","article-title":"Preparation and application of ultra-thin two dimensional MOF nanomaterials","volume":"33","author":"Chen","year":"2021","journal-title":"Prog. Chem."},{"key":"10.1016\/j.talanta.2023.124377_bib14","doi-asserted-by":"crossref","first-page":"17257","DOI":"10.1021\/acsami.8b04600","article-title":"Database for CO2 separation performances of MOFs based on computational materials screening","volume":"10","author":"Altintas","year":"2018","journal-title":"ACS Appl. Mater. Interfaces"},{"key":"10.1016\/j.talanta.2023.124377_bib15","article-title":"CeO2 modified Ni-MOF as an efficient catalyst for electrocatalytic urea oxidation","volume":"1","author":"Wu","year":"2022","journal-title":"Mater. Lab."},{"key":"10.1016\/j.talanta.2023.124377_bib16","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1016\/j.ccr.2018.09.009","article-title":"Application of zirconium MOFs in drug delivery and biomedicine","volume":"380","author":"Ab\u00e1nades L\u00e1zaro","year":"2019","journal-title":"Coord. Chem. Rev."},{"key":"10.1016\/j.talanta.2023.124377_bib17","doi-asserted-by":"crossref","DOI":"10.1016\/j.bios.2020.112947","article-title":"Aptamer-functionalized metal-organic frameworks (MOFs) for biosensing","volume":"176","author":"Lv","year":"2021","journal-title":"Biosens. Bioelectron."},{"issue":"4","key":"10.1016\/j.talanta.2023.124377_bib18","doi-asserted-by":"crossref","first-page":"572","DOI":"10.3390\/ma11040572","article-title":"Luminescent lanthanide MOFs: a unique platform for chemical sensing","volume":"11","author":"Zhao","year":"2018","journal-title":"Materials"},{"key":"10.1016\/j.talanta.2023.124377_bib19","doi-asserted-by":"crossref","first-page":"10745","DOI":"10.1039\/D0DT01648A","article-title":"The first ternary Nd-MOF\/GO\/Fe3O4 nanocomposite exhibiting an excellent photocatalytic performance for dye degradation","volume":"49","author":"Bai","year":"2020","journal-title":"Dalton Trans."},{"key":"10.1016\/j.talanta.2023.124377_bib20","doi-asserted-by":"crossref","DOI":"10.1016\/j.jssc.2021.122508","article-title":"A nanoscale Nd-based metal-organic framework electrochemical sensor for rapid detection of Rhodamine B","volume":"303","author":"Feng","year":"2021","journal-title":"J. Solid State Chem."},{"key":"10.1016\/j.talanta.2023.124377_bib21","doi-asserted-by":"crossref","first-page":"59164","DOI":"10.1021\/acsami.1c20817","article-title":"Near-infrared emissive lanthanide metal\u2013organic frameworks for targeted biological imaging and pH-controlled chemotherapy","volume":"13","author":"Cui","year":"2021","journal-title":"ACS Appl. Mater. Interfaces"},{"key":"10.1016\/j.talanta.2023.124377_bib22","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1126\/science.1246738","article-title":"Tunable electrical conductivity in metal-organic framework thin-film devices","volume":"343","author":"Talin","year":"2014","journal-title":"Science"},{"key":"10.1016\/j.talanta.2023.124377_bib23","doi-asserted-by":"crossref","DOI":"10.1002\/adfm.202005522","article-title":"Ionic liquid-based stimuli-responsive functional materials","volume":"30","author":"Cui","year":"2020","journal-title":"Adv. Funct. Mater."},{"key":"10.1016\/j.talanta.2023.124377_bib24","doi-asserted-by":"crossref","first-page":"1290","DOI":"10.1002\/anie.202010783","article-title":"MOF-directed synthesis of crystalline ionic liquids with enhanced proton conduction","volume":"60","author":"Xue","year":"2021","journal-title":"Angew. Chem. Int. Ed."},{"key":"10.1016\/j.talanta.2023.124377_bib25","doi-asserted-by":"crossref","first-page":"19066","DOI":"10.1039\/D1NR05782K","article-title":"Dual-wavelength responsive photoelectrochemical aptasensor based on ionic liquid functionalized Zn-MOFs and noble metal nanoparticles for the simultaneous detection of multiple tumor markers","volume":"13","author":"Zhong","year":"2021","journal-title":"Nanoscale"}],"container-title":["Talanta"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0039914023001285?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0039914023001285?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T06:54:37Z","timestamp":1777445677000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0039914023001285"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,6]]},"references-count":25,"alternative-id":["S0039914023001285"],"URL":"https:\/\/doi.org\/10.1016\/j.talanta.2023.124377","relation":{},"ISSN":["0039-9140"],"issn-type":[{"value":"0039-9140","type":"print"}],"subject":[],"published":{"date-parts":[[2023,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"A high performance dual-mode biosensor based on Nd-MOF nanosheets functionalized with ionic liquid and gold nanoparticles for sensing of ctDNA","name":"articletitle","label":"Article Title"},{"value":"Talanta","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.talanta.2023.124377","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"124377"}}