{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,23]],"date-time":"2026-08-23T17:57:59Z","timestamp":1787507879835,"version":"build-2736575974"},"reference-count":36,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,5,1]],"date-time":"2024-05-01T00:00:00Z","timestamp":1714521600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,5,1]],"date-time":"2024-05-01T00:00:00Z","timestamp":1714521600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,5,1]],"date-time":"2024-05-01T00:00:00Z","timestamp":1714521600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2024,5,1]],"date-time":"2024-05-01T00:00:00Z","timestamp":1714521600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2024,5,1]],"date-time":"2024-05-01T00:00:00Z","timestamp":1714521600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2024,5,1]],"date-time":"2024-05-01T00:00:00Z","timestamp":1714521600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2024,5,1]],"date-time":"2024-05-01T00:00:00Z","timestamp":1714521600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["21974083"],"award-info":[{"award-number":["21974083"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100017596","name":"Natural Science Basic Research Program of Shaanxi Province","doi-asserted-by":"publisher","award":["2021JZ-23"],"award-info":[{"award-number":["2021JZ-23"]}],"id":[{"id":"10.13039\/501100017596","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Talanta"],"published-print":{"date-parts":[[2024,5]]},"DOI":"10.1016\/j.talanta.2024.125656","type":"journal-article","created":{"date-parts":[[2024,1,11]],"date-time":"2024-01-11T11:28:14Z","timestamp":1704972494000},"page":"125656","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":14,"special_numbering":"C","title":["Entropy-driven catalysis-based lateral flow assay for sensitive detection of Alzheimer 's-associated MicroRNA"],"prefix":"10.1016","volume":"271","author":[{"given":"Jing","family":"Wang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lu","family":"Shi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinyu","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qiaorong","family":"Tang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mengmeng","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Baoxin","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yan","family":"Jin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.talanta.2024.125656_bib1","doi-asserted-by":"crossref","first-page":"484","DOI":"10.1016\/S1474-4422(21)00066-1","article-title":"Clinical diagnosis of Alzheimer's disease: recommendations of the international working group","volume":"20","author":"Dubois","year":"2021","journal-title":"Lancet Neurol."},{"key":"10.1016\/j.talanta.2024.125656_bib2","doi-asserted-by":"crossref","first-page":"313","DOI":"10.14283\/jpad.2021.15","article-title":"The epidemiology of Alzheimer's disease modifiable risk factors and prevention","volume":"8","author":"Zhang","year":"2021","journal-title":"J. Prev. Alzheimer's Dis."},{"key":"10.1016\/j.talanta.2024.125656_bib3","doi-asserted-by":"crossref","first-page":"543","DOI":"10.4103\/1673-5374.320970","article-title":"Pathological mechanisms and therapeutic strategies for Alzheimer's disease","volume":"17","author":"Ju","year":"2022","journal-title":"Neural. Regen. Res."},{"key":"10.1016\/j.talanta.2024.125656_bib4","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1038\/nrneph.2014.202","article-title":"MicroRNAs in kidney physiology and disease","volume":"11","author":"Trionfini","year":"2015","journal-title":"Nat. Rev. Nephrol."},{"key":"10.1016\/j.talanta.2024.125656_bib5","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1002\/jcp.25056","article-title":"MicroRNA as biomarkers and diagnostics","volume":"231","author":"Wang","year":"2016","journal-title":"J. Cell. Physiol."},{"key":"10.1016\/j.talanta.2024.125656_bib6","doi-asserted-by":"crossref","first-page":"784","DOI":"10.1136\/gutjnl-2020-322526","article-title":"MicroRNAs as regulators, biomarkers and therapeutic targets in liver diseases","volume":"70","author":"Wang","year":"2021","journal-title":"GUT"},{"key":"10.1016\/j.talanta.2024.125656_bib7","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1186\/s40035-022-00296-z","article-title":"Advances in the development of new biomarkers for Alzheimer's disease","volume":"11","author":"Klyucherev","year":"2022","journal-title":"Transl. Neurodegener."},{"key":"10.1016\/j.talanta.2024.125656_bib8","doi-asserted-by":"crossref","first-page":"6156","DOI":"10.1007\/s12035-019-1500-y","article-title":"Systematic review of miRNA as biomarkers in Alzheimer's disease","volume":"56","author":"Swarbrick","year":"2019","journal-title":"Mol. Neurobiol."},{"key":"10.1016\/j.talanta.2024.125656_bib9","doi-asserted-by":"crossref","DOI":"10.1016\/j.pneurobio.2019.101732","article-title":"Circulating microRNAs as potential biomarkers for psychiatric and neurodegenerative disorders","volume":"185","author":"van den Berg","year":"2020","journal-title":"Prog. Neurobiol."},{"key":"10.1016\/j.talanta.2024.125656_bib10","doi-asserted-by":"crossref","first-page":"1256","DOI":"10.1038\/s41380-021-01351-3","article-title":"Human microRNA (miR-20b-5p) modulates Alzheimer's disease pathways and neuronal function, and a specific polymorphism close to the MIR20B gene influences Alzheimer's biomarkers","volume":"27","author":"Wang","year":"2022","journal-title":"Mol. Psychiatr."},{"key":"10.1016\/j.talanta.2024.125656_bib11","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0196929","article-title":"Defensive effect of microRNA-200b\/c against amyloid-beta peptide-induced toxicity in Alzheimer's disease models","volume":"13","author":"Higaki","year":"2018","journal-title":"PLoS One"},{"key":"10.1016\/j.talanta.2024.125656_bib12","doi-asserted-by":"crossref","DOI":"10.1016\/j.bios.2022.114279","article-title":"miRNA sensing hydrogels capable of self-signal amplification for early diagnosis of Alzheimer's disease","volume":"209","author":"Lim","year":"2022","journal-title":"Biosens. Bioelectron."},{"key":"10.1016\/j.talanta.2024.125656_bib13","doi-asserted-by":"crossref","first-page":"e1463","DOI":"10.1002\/wrna.1463","article-title":"Noncoding RNAs in Alzheimer's disease","volume":"9","author":"Idda","year":"2018","journal-title":"Wiley Interdiscip Rev. RNA."},{"key":"10.1016\/j.talanta.2024.125656_bib14","doi-asserted-by":"crossref","first-page":"8346","DOI":"10.1021\/acs.analchem.2c00831","article-title":"Dynamic 3D DNA rolling walkers via directional movement on a lipid bilayer supported by Au@Fe3O4 nanoparticles for sensitive detection of miRNA-16","volume":"94","author":"Zhang","year":"2022","journal-title":"Anal. Chem."},{"key":"10.1016\/j.talanta.2024.125656_bib15","doi-asserted-by":"crossref","DOI":"10.1016\/j.snb.2021.130325","article-title":"Gold-platinum nanoflowers as colored and catalytic labels for ultrasensitive lateral flow microRNA-21 assay","volume":"344","author":"Zhang","year":"2021","journal-title":"Sensor. Actuator. B Chem."},{"key":"10.1016\/j.talanta.2024.125656_bib16","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1016\/j.bios.2014.04.049","article-title":"Ultrasensitive detection of mercury with a novel one-step signal amplified lateral flow strip based on gold nanoparticle-labeled ssDNA recognition and enhancement probes","volume":"61","author":"Zhu","year":"2014","journal-title":"Biosens. Bioelectron."},{"key":"10.1016\/j.talanta.2024.125656_bib17","doi-asserted-by":"crossref","first-page":"2469","DOI":"10.1039\/c2lc40100b","article-title":"Isothermal nucleic acid amplification technologies for point-of-care diagnostics: a critical review","volume":"12","author":"Craw","year":"2012","journal-title":"Lab Chip"},{"key":"10.1016\/j.talanta.2024.125656_bib18","doi-asserted-by":"crossref","DOI":"10.1016\/j.biotechadv.2019.107442","article-title":"Paper-based point-of-care immunoassays: recent advances and emerging trends","volume":"39","author":"Li","year":"2020","journal-title":"Biotechnol. Adv."},{"key":"10.1016\/j.talanta.2024.125656_bib19","doi-asserted-by":"crossref","first-page":"1605","DOI":"10.3390\/foods10071605","article-title":"An enhanced lateral flow assay based on aptamer-magnetic separation and multifold AuNPs for ultrasensitive detection of salmonella typhimurium in milk","volume":"10","author":"Gao","year":"2021","journal-title":"Foods"},{"key":"10.1016\/j.talanta.2024.125656_bib20","doi-asserted-by":"crossref","DOI":"10.1016\/j.ab.2019.113432","article-title":"Visual detection of kanamycin with DNA-functionalized gold nanoparticles probe in aptamer-based strip biosensor","volume":"587","author":"Ou","year":"2019","journal-title":"Anal. Biochem."},{"key":"10.1016\/j.talanta.2024.125656_bib21","doi-asserted-by":"crossref","DOI":"10.1016\/j.bios.2022.114345","article-title":"Recent advances in the rapid detection of microRNA with lateral flow assays","volume":"211","author":"Wang","year":"2022","journal-title":"Biosens. Bioelectron."},{"key":"10.1016\/j.talanta.2024.125656_bib22","doi-asserted-by":"crossref","first-page":"320","DOI":"10.1016\/j.snb.2018.02.159","article-title":"Lateral flow test for visual detection of multiple microRNAs","volume":"264","author":"Zheng","year":"2018","journal-title":"Sensor. Actuator. B Chem."},{"key":"10.1016\/j.talanta.2024.125656_bib23","doi-asserted-by":"crossref","DOI":"10.1016\/j.talanta.2022.123306","article-title":"DNA barcode-based detection of exosomal microRNAs using nucleic acid lateral flow assays for the diagnosis of colorectal cancer","volume":"242","author":"Kim","year":"2022","journal-title":"Talanta"},{"key":"10.1016\/j.talanta.2024.125656_bib24","doi-asserted-by":"crossref","first-page":"558","DOI":"10.1039\/D0AN01673J","article-title":"Duplex-specific nuclease signal amplification-based fluorescent lateral flow assay for the point-of-care detection of microRNAs","volume":"146","author":"Wei","year":"2021","journal-title":"Analyst"},{"key":"10.1016\/j.talanta.2024.125656_bib25","doi-asserted-by":"crossref","DOI":"10.1016\/j.bios.2023.115179","article-title":"An ultra-sensitive one-pot RNA-templated DNA ligation rolling circle amplification-assisted CRISPR\/Cas12a detector assay for rapid detection of SARS-CoV-2","volume":"228","author":"Zhu","year":"2023","journal-title":"Biosens. Bioelectron."},{"key":"10.1016\/j.talanta.2024.125656_bib26","doi-asserted-by":"crossref","first-page":"6781","DOI":"10.1021\/acs.analchem.7b01149","article-title":"Dual recognition element lateral flow assay toward multiplex strain specific influenza virus detection","volume":"89","author":"Le","year":"2017","journal-title":"Anal. Chem."},{"key":"10.1016\/j.talanta.2024.125656_bib27","doi-asserted-by":"crossref","DOI":"10.1016\/j.bios.2021.113015","article-title":"Entropy-driven amplified electrochemiluminescence biosensor for RdRp gene of SARS-CoV-2 detection with self-assembled DNA tetrahedron scaffolds","volume":"178","author":"Fan","year":"2021","journal-title":"Biosens. Bioelectron."},{"key":"10.1016\/j.talanta.2024.125656_bib28","doi-asserted-by":"crossref","first-page":"830","DOI":"10.1126\/science.abe1292","article-title":"High-entropy-stabilized chalcogenides with high thermoelectric performance","volume":"371","author":"Jiang","year":"2021","journal-title":"Science"},{"key":"10.1016\/j.talanta.2024.125656_bib29","doi-asserted-by":"crossref","first-page":"9077","DOI":"10.1002\/anie.201704147","article-title":"Rational engineering of a dynamic, entropy-driven DNA nanomachine for intracellular microRNA imaging","volume":"56","author":"Liang","year":"2017","journal-title":"Angew. Chem., Int. Ed. Engl."},{"key":"10.1016\/j.talanta.2024.125656_bib30","doi-asserted-by":"crossref","DOI":"10.1016\/j.bios.2020.112942","article-title":"Entropy-driven electrochemiluminescence ultra-sensitive detection strategy of NF-kappa B p50 as the regulator of cytokine storm","volume":"176","author":"Zhang","year":"2021","journal-title":"Biosens. Bioelectron."},{"key":"10.1016\/j.talanta.2024.125656_bib31","doi-asserted-by":"crossref","first-page":"4281","DOI":"10.1039\/C7CS00055C","article-title":"Hybridization chain reaction: a versatile molecular tool for biosensing, bioimaging, and biomedicine","volume":"46","author":"Bi","year":"2017","journal-title":"Chem. Soc. Rev."},{"key":"10.1016\/j.talanta.2024.125656_bib32","doi-asserted-by":"crossref","first-page":"1985","DOI":"10.1039\/C9SC04916A","article-title":"An intramolecular catalytic hairpin assembly on a DNA tetrahedron for mRNA imaging in living cells: improving reaction kinetics and signal stability","volume":"11","author":"Qing","year":"2020","journal-title":"Chem. Sci."},{"issue":"16","key":"10.1016\/j.talanta.2024.125656_bib33","doi-asserted-by":"crossref","first-page":"7506","DOI":"10.1021\/jacs.0c00217","article-title":"Single-step, salt-aging-free, and thiol-free freezing construction of AuNP-based bioprobes for advancing CRISPR-based diagnostics","volume":"142","author":"Hu","year":"2020","journal-title":"J. Am. Chem. Soc."},{"issue":"28","key":"10.1016\/j.talanta.2024.125656_bib34","doi-asserted-by":"crossref","first-page":"9471","DOI":"10.1021\/jacs.7b04885","article-title":"Freezing directed construction of bio\/nano interfaces: reagentless conjugation, denser spherical nucleic acids, and better nanoflares","volume":"139","author":"Liu","year":"2017","journal-title":"J. Am. Chem. Soc."},{"key":"10.1016\/j.talanta.2024.125656_bib35","doi-asserted-by":"crossref","first-page":"9077","DOI":"10.1002\/anie.201704147","article-title":"Rational engineering of a dynamic, entropy-driven dna nanomachine for intracellular microRNA imaging","volume":"56","author":"Liang","year":"2017","journal-title":"Angew. Chem. Int. Ed."},{"key":"10.1016\/j.talanta.2024.125656_bib36","doi-asserted-by":"crossref","first-page":"11714","DOI":"10.1021\/acs.analchem.5b02654","article-title":"Entropy beacon: a hairpin-free dna amplification strategy forefficient detection of nucleic acids","volume":"87","author":"Lv","year":"2015","journal-title":"Anal. Chem."}],"container-title":["Talanta"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0039914024000353?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0039914024000353?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,22]],"date-time":"2025-09-22T13:12:55Z","timestamp":1758546775000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0039914024000353"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,5]]},"references-count":36,"alternative-id":["S0039914024000353"],"URL":"https:\/\/doi.org\/10.1016\/j.talanta.2024.125656","relation":{},"ISSN":["0039-9140"],"issn-type":[{"value":"0039-9140","type":"print"}],"subject":[],"published":{"date-parts":[[2024,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Entropy-driven catalysis-based lateral flow assay for sensitive detection of Alzheimer 's-associated MicroRNA","name":"articletitle","label":"Article Title"},{"value":"Talanta","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.talanta.2024.125656","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"125656"}}