{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,21]],"date-time":"2026-07-21T03:53:11Z","timestamp":1784605991926,"version":"3.55.0"},"reference-count":40,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["22304105"],"award-info":[{"award-number":["22304105"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100014718","name":"Innovative Research Group Project of the National Natural Science Foundation of China","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100014718","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100007129","name":"Shandong Province Natural Science Foundation","doi-asserted-by":"publisher","award":["ZR2021MB048"],"award-info":[{"award-number":["ZR2021MB048"]}],"id":[{"id":"10.13039\/501100007129","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100007129","name":"Shandong Province Natural Science Foundation","doi-asserted-by":"publisher","award":["ZR2022QB151"],"award-info":[{"award-number":["ZR2022QB151"]}],"id":[{"id":"10.13039\/501100007129","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Talanta"],"published-print":{"date-parts":[[2025,1]]},"DOI":"10.1016\/j.talanta.2024.127052","type":"journal-article","created":{"date-parts":[[2024,10,17]],"date-time":"2024-10-17T03:15:01Z","timestamp":1729134901000},"page":"127052","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":9,"special_numbering":"C","title":["Enhanced electrochemiluminescence of CdS QDs encapsulated in IRMOF-3 for sensitive detection of human epithelial protein 4"],"prefix":"10.1016","volume":"282","author":[{"given":"Xinyu","family":"Liu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dongyu","family":"Han","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Feng","family":"Jiang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shanghua","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yueyuan","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhen","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qing","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yueyun","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qin","family":"Wei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"19","key":"10.1016\/j.talanta.2024.127052_bib1","doi-asserted-by":"crossref","first-page":"12234","DOI":"10.1021\/acs.chemrev.6b00290","article-title":"New generation cadmium-free quantum dots for biophotonics and nanomedicine","volume":"116","author":"Xu","year":"2016","journal-title":"Chem. Rev."},{"issue":"16","key":"10.1016\/j.talanta.2024.127052_bib2","doi-asserted-by":"crossref","first-page":"6655","DOI":"10.1021\/acs.analchem.3c00058","article-title":"Controlled growth of MoS2 on dendritic ferric oxide to enhance electrochemiluminescence of nitrogen-doped carbon quantum dots for sensitive immunoassay","volume":"95","author":"Han","year":"2023","journal-title":"Anal. Chem."},{"issue":"3","key":"10.1016\/j.talanta.2024.127052_bib3","doi-asserted-by":"crossref","first-page":"1818","DOI":"10.1021\/acs.analchem.0c04717","article-title":"Hierarchical metal\u2013organic framework-confined CsPbBr3 quantum dots and aminated carbon dots: a new self-sustaining suprastructure for electrochemiluminescence bioanalysis","volume":"93","author":"Cao","year":"2020","journal-title":"Anal. Chem."},{"key":"10.1016\/j.talanta.2024.127052_bib4","article-title":"Metal-Organic framework incorporated luminescent PTCA combined with novel co-reactant accelerator for ultra-sensitive electrochemiluminescence detection of CA19-9","volume":"495","author":"Li","year":"2024","journal-title":"Chem. Eng. J."},{"key":"10.1016\/j.talanta.2024.127052_bib5","doi-asserted-by":"crossref","DOI":"10.1016\/j.electacta.2020.136644","article-title":"A novel electrochemiluminescence aptasensor based CdTe QDs@NH2-MIL-88(Fe) for signal amplification","volume":"354","author":"Chen","year":"2020","journal-title":"Electrochim. Acta"},{"key":"10.1016\/j.talanta.2024.127052_bib6","doi-asserted-by":"crossref","DOI":"10.1016\/j.bios.2019.111970","article-title":"Enhanced electrochemiluminescence of luminol based on Cu2O\u2013Au heterostructure enabled multiple-amplification strategy","volume":"151","author":"Zhu","year":"2020","journal-title":"Biosens. Bioelectron."},{"key":"10.1016\/j.talanta.2024.127052_bib7","doi-asserted-by":"crossref","DOI":"10.1016\/j.talanta.2024.126375","article-title":"An ultrasensitive solid-state electrochemiluminescence sensor based on Ni-MOF@Ru(bpy)32+ and Au NPs@TiO2 for determination of permethrin","volume":"277","author":"Yang","year":"2024","journal-title":"Talanta"},{"issue":"6","key":"10.1016\/j.talanta.2024.127052_bib8","doi-asserted-by":"crossref","first-page":"3995","DOI":"10.1021\/acs.analchem.7b05137","article-title":"Strong electrochemiluminescence from MOF accelerator enriched quantum dots for enhanced sensing of trace cTnI","volume":"90","author":"Yang","year":"2018","journal-title":"Anal. Chem."},{"issue":"5","key":"10.1016\/j.talanta.2024.127052_bib9","doi-asserted-by":"crossref","first-page":"3681","DOI":"10.1021\/acs.analchem.8b05795","article-title":"Novel Ru(bpy)2(cpaphen)2+\/TPrA\/TiO2 ternary ECL system: an efficient platform for the detection of glutathione with Mn2+ as substitute target","volume":"91","author":"Zhang","year":"2019","journal-title":"Anal. Chem."},{"key":"10.1016\/j.talanta.2024.127052_bib10","doi-asserted-by":"crossref","DOI":"10.1016\/j.talanta.2024.125934","article-title":"The dual ECL signal enhancement strategy of Pd nanoparticles attached covalent organic frameworks and exonuclease cycling reaction for the ultrasensitive detection of progesterone","volume":"274","author":"Pan","year":"2024","journal-title":"Talanta"},{"issue":"75","key":"10.1016\/j.talanta.2024.127052_bib11","doi-asserted-by":"crossref","first-page":"10989","DOI":"10.1039\/D0CC04371K","article-title":"Recent advances in co-reaction accelerators for sensitive electrochemiluminescence analysis","volume":"56","author":"Hu","year":"2020","journal-title":"Chem. Commun."},{"issue":"21","key":"10.1016\/j.talanta.2024.127052_bib12","doi-asserted-by":"crossref","first-page":"4768","DOI":"10.1039\/D2AN01341J","article-title":"Electrochemiluminescence biosensor for cardiac troponin I with signal amplification based on a MoS2@Cu2O\u2013Ag-modified electrode and Ce:ZnO-NGQDs","volume":"147","author":"Wang","year":"2022","journal-title":"Analyst"},{"issue":"25","key":"10.1016\/j.talanta.2024.127052_bib13","doi-asserted-by":"crossref","first-page":"9176","DOI":"10.1021\/acs.analchem.2c01868","article-title":"High-efficiency CdSe quantum dots\/Fe3O4@MoS2\/S2O82\u2013 electrochemiluminescence system based on a microfluidic analysis platform for the sensitive detection of neuron-specific enolase","volume":"94","author":"Feng","year":"2022","journal-title":"Anal. Chem."},{"issue":"12","key":"10.1016\/j.talanta.2024.127052_bib14","doi-asserted-by":"crossref","first-page":"4969","DOI":"10.1021\/acs.analchem.4c00019","article-title":"Ultrasensitive electrochemiluminescence biosensor based on efficient signal amplification of copper nanoclusters induced by CaMnO3 for CD44 trace detection","volume":"96","author":"Qi","year":"2024","journal-title":"Anal. Chem."},{"issue":"6","key":"10.1016\/j.talanta.2024.127052_bib15","doi-asserted-by":"crossref","first-page":"2057","DOI":"10.1039\/D0AN02296A","article-title":"Ultrasensitive detection of cyclin D1 by a self-enhanced ECL immunosensor based on Bi2S3quantum dots","volume":"146","author":"Liu","year":"2021","journal-title":"Analyst"},{"key":"10.1016\/j.talanta.2024.127052_bib16","doi-asserted-by":"crossref","DOI":"10.1016\/j.cej.2023.146958","article-title":"Electrochemiluminescent quantum dots as emerging next generation sensing platforms","volume":"477","author":"Mehta","year":"2023","journal-title":"Chem. Eng. J."},{"key":"10.1016\/j.talanta.2024.127052_bib17","doi-asserted-by":"crossref","DOI":"10.1016\/j.talanta.2023.125393","article-title":"Enhancing electrochemiluminescence by modifying Fe3CuO4 and CdS@ZnS: a novel ECL sensor for highly sensitive detection of permethrin","volume":"268","author":"Wu","year":"2024","journal-title":"Talanta"},{"issue":"7","key":"10.1016\/j.talanta.2024.127052_bib18","doi-asserted-by":"crossref","DOI":"10.3390\/bios13070708","article-title":"Electrochemiluminescence of semiconductor quantum dots and its biosensing applications: a comprehensive review","volume":"13","author":"Sun","year":"2023","journal-title":"Biosensors"},{"issue":"19","key":"10.1016\/j.talanta.2024.127052_bib19","doi-asserted-by":"crossref","first-page":"7516","DOI":"10.1021\/acs.analchem.4c00225","article-title":"Single-atom iron doped carbon dots with highly efficient electrochemiluminescence for ultrasensitive detection of MicroRNAs","volume":"96","author":"Liao","year":"2024","journal-title":"Anal. Chem."},{"key":"10.1016\/j.talanta.2024.127052_bib20","doi-asserted-by":"crossref","first-page":"7776","DOI":"10.1007\/s12274-024-6707-1","article-title":"Ligand-controlled electrochemiluminescence generation from CdSe\/CdS\/ZnS core\/shell\/shell quantum dots","volume":"17","author":"Sun","year":"2024","journal-title":"Nano Res."},{"issue":"47","key":"10.1016\/j.talanta.2024.127052_bib21","doi-asserted-by":"crossref","first-page":"16510","DOI":"10.1021\/acs.analchem.2c04387","article-title":"Construction of carbon dots with wavelength-tunable electrochemiluminescence and enhanced efficiency","volume":"94","author":"Yang","year":"2022","journal-title":"Anal. Chem."},{"issue":"15","key":"10.1016\/j.talanta.2024.127052_bib22","doi-asserted-by":"crossref","first-page":"2334","DOI":"10.1039\/C7AY00295E","article-title":"A sensitive and selective electrochemiluminescent sensor for dopamine based on the inhibition of dual-stabilizer-capped CdS quantum dot electrochemiluminescence","volume":"9","author":"Yang","year":"2017","journal-title":"Anal. Methods"},{"key":"10.1016\/j.talanta.2024.127052_bib23","doi-asserted-by":"crossref","DOI":"10.1016\/j.talo.2022.100088","article-title":"Recent advances in II-VI quantum dots based-signal strategy of electrochemiluminescence sensor","volume":"5","author":"Wang","year":"2022","journal-title":"Talanta Open"},{"issue":"17","key":"10.1016\/j.talanta.2024.127052_bib24","doi-asserted-by":"crossref","first-page":"7045","DOI":"10.1021\/acs.analchem.3c00729","article-title":"Aggregation-induced electrochemiluminescence based on a zinc-based metal\u2013organic framework and a double quencher Au@UiO-66-NH2 for the sensitive detection of amyloid \u03b2 42 via resonance energy transfer","volume":"95","author":"Yang","year":"2023","journal-title":"Anal. Chem."},{"issue":"4","key":"10.1016\/j.talanta.2024.127052_bib25","doi-asserted-by":"crossref","first-page":"1921","DOI":"10.1021\/acs.chemmater.1c04355","article-title":"Encapsulating CdSe\/CdS QDs in the MOF ZIF-8 enhances their photoluminescence quantum yields in the solid state","volume":"34","author":"Stone","year":"2022","journal-title":"Chem. Mater."},{"key":"10.1016\/j.talanta.2024.127052_bib26","doi-asserted-by":"crossref","DOI":"10.1016\/j.talanta.2019.120376","article-title":"Electrochemiluminescence immunosensor of \u201csignal-off\u201d for \u03b2-amyloid detection based on dual metal-organic frameworks","volume":"208","author":"Dong","year":"2020","journal-title":"Talanta"},{"issue":"23","key":"10.1016\/j.talanta.2024.127052_bib27","doi-asserted-by":"crossref","first-page":"8561","DOI":"10.1039\/D4TC01594K","article-title":"MXene quantum dot functionalized bimetallic MOFs as a label-free aptasensor for highly sensitive detection of exosomes","volume":"12","author":"Su","year":"2024","journal-title":"J. Mater. Chem. C"},{"issue":"27","key":"10.1016\/j.talanta.2024.127052_bib28","doi-asserted-by":"crossref","first-page":"11044","DOI":"10.1021\/acs.analchem.4c01894","article-title":"Highly electroactive Co2+-based metal\u2013organic frameworks as an efficient coreaction accelerator for amplifying near-infrared electrochemiluminescence of gold nanoclusters in biomarkers immunoassay","volume":"96","author":"Jia","year":"2024","journal-title":"Anal. Chem."},{"key":"10.1016\/j.talanta.2024.127052_bib29","doi-asserted-by":"crossref","DOI":"10.1016\/j.bios.2019.111768","article-title":"An ultrasensitive ratiometric electrochemiluminescence immunosensor combining photothermal amplification for ovarian cancer marker detection","volume":"146","author":"Fang","year":"2019","journal-title":"Biosens. Bioelectron."},{"key":"10.1016\/j.talanta.2024.127052_bib30","doi-asserted-by":"crossref","DOI":"10.1016\/j.snb.2021.130495","article-title":"Dual-quenching electrochemiluminescence resonance energy transfer system from IRMOF-3 coreaction accelerator enriched nitrogen-doped GQDs to ZnO@Au for sensitive detection of procalcitonin","volume":"346","author":"Hu","year":"2021","journal-title":"Sensor. Actuator. B Chem."},{"issue":"12","key":"10.1016\/j.talanta.2024.127052_bib31","doi-asserted-by":"crossref","first-page":"5301","DOI":"10.1021\/acs.analchem.1c00446","article-title":"Development of hollow electrochemiluminescent nanocubes combined with a multisite-anchored DNA nanomachine for mycotoxin detection","volume":"93","author":"Zhong","year":"2021","journal-title":"Anal. Chem."},{"key":"10.1016\/j.talanta.2024.127052_bib32","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1016\/j.elecom.2013.04.029","article-title":"Sensitive and selective electrochemiluminescent detection of nitrite using dual-stabilizer-capped CdTe quantum dots","volume":"34","author":"Yin","year":"2013","journal-title":"Electrochem. Commun."},{"issue":"37","key":"10.1016\/j.talanta.2024.127052_bib33","doi-asserted-by":"crossref","first-page":"12852","DOI":"10.1021\/acs.analchem.2c02852","article-title":"Mixed-ligand-regulated self-enhanced luminous Eu-MOF as an ECL signal probe for an oriented antibody-decorated biosensing platform","volume":"94","author":"Dong","year":"2022","journal-title":"Anal. Chem."},{"issue":"4","key":"10.1016\/j.talanta.2024.127052_bib34","doi-asserted-by":"crossref","first-page":"1295","DOI":"10.1039\/D0AN02158J","article-title":"A novel signal amplified electrochemiluminescence biosensor based on MIL-53(Al)@CdS QDs and SiO2@AuNPs for trichlorfon detection","volume":"146","author":"Feng","year":"2021","journal-title":"Analyst"},{"key":"10.1016\/j.talanta.2024.127052_bib35","doi-asserted-by":"crossref","DOI":"10.1016\/j.snb.2020.128298","article-title":"2D hexagonal SnS2 nanoplates as novel co-reaction accelerator for construction of ultrasensitive g-C3N4-based electrochemiluminescent biosensor","volume":"319","author":"Zhou","year":"2020","journal-title":"Sensor. Actuator. B Chem."},{"issue":"43","key":"10.1016\/j.talanta.2024.127052_bib36","doi-asserted-by":"crossref","first-page":"15155","DOI":"10.1021\/acs.analchem.2c03606","article-title":"Smartphone-based electrochemical immunoassay for point-of-care detection of SARS-CoV-2 nucleocapsid protein","volume":"94","author":"Zeng","year":"2022","journal-title":"Anal. Chem."},{"key":"10.1016\/j.talanta.2024.127052_bib37","doi-asserted-by":"crossref","DOI":"10.1016\/j.aca.2021.339160","article-title":"Fluorescence turn-on immunosensing of HE4 biomarker and ovarian cancer cells based on target-triggered metal-enhanced fluorescence of carbon dots","volume":"1187","author":"Han","year":"2021","journal-title":"Anal. Chim. Acta"},{"key":"10.1016\/j.talanta.2024.127052_bib38","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1016\/j.talanta.2018.01.054","article-title":"Electrochemical quantum dots-based magneto-immunoassay for detection of HE4 protein on metal film-modified screen-printed carbon electrodes","volume":"182","author":"Cadkova","year":"2018","journal-title":"Talanta"},{"issue":"1","key":"10.1016\/j.talanta.2024.127052_bib39","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1016\/j.bios.2012.01.004","article-title":"Ultrasensitive electrochemical immunosensor for HE4 based on rolling circle amplification","volume":"33","author":"Lu","year":"2012","journal-title":"Biosens. Bioelectron."},{"issue":"22","key":"10.1016\/j.talanta.2024.127052_bib40","doi-asserted-by":"crossref","first-page":"12391","DOI":"10.1021\/acs.analchem.7b03486","article-title":"Molecularly imprinted photo-electrochemical sensor for human epididymis protein 4 based on polymerized ionic liquid hydrogel and gold nanoparticle\/ZnCdHgSe quantum dots composite film","volume":"89","author":"Wang","year":"2017","journal-title":"Anal. Chem."}],"container-title":["Talanta"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0039914024014310?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0039914024014310?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,11,17]],"date-time":"2024-11-17T17:34:54Z","timestamp":1731864894000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0039914024014310"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,1]]},"references-count":40,"alternative-id":["S0039914024014310"],"URL":"https:\/\/doi.org\/10.1016\/j.talanta.2024.127052","relation":{},"ISSN":["0039-9140"],"issn-type":[{"value":"0039-9140","type":"print"}],"subject":[],"published":{"date-parts":[[2025,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Enhanced electrochemiluminescence of CdS QDs encapsulated in IRMOF-3 for sensitive detection of human epithelial protein 4","name":"articletitle","label":"Article Title"},{"value":"Talanta","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.talanta.2024.127052","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"127052"}}