{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T04:05:12Z","timestamp":1790827512277,"version":"4.1.0"},"reference-count":41,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100012166","name":"National Key Research and Development Program of China","doi-asserted-by":"publisher","award":["2022YFF1102500"],"award-info":[{"award-number":["2022YFF1102500"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Talanta"],"published-print":{"date-parts":[[2025,12]]},"DOI":"10.1016\/j.talanta.2025.128257","type":"journal-article","created":{"date-parts":[[2025,5,2]],"date-time":"2025-05-02T02:07:12Z","timestamp":1746151632000},"page":"128257","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":13,"special_numbering":"C","title":["A MOF-818-based nanozyme-linked aptasensor for microcystin-LR detection in edible algae powder"],"prefix":"10.1016","volume":"295","author":[{"given":"Junlan","family":"Yu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenjie","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiachen","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guijie","family":"Hao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhe","family":"Feng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9972-7805","authenticated-orcid":false,"given":"Fangkai","family":"Han","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiahua","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaodan","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fuwei","family":"Pi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huang","family":"Dai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xin","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yafang","family":"Shen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"2","key":"10.1016\/j.talanta.2025.128257_bib1","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1039\/D2AN01680J","article-title":"Molecularly imprinted nanoparticle-based assay (MINA) for microcystin-LR detection in water","volume":"148","author":"Garcia","year":"2023","journal-title":"Analyst"},{"key":"10.1016\/j.talanta.2025.128257_bib2","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1016\/j.bios.2016.02.072","article-title":"Fabricating photoelectrochemical aptasensor for selectively monitoring microcystin-LR residues in fish based on visible light-responsive BiOBr nanoflakes\/N-doped graphene photoelectrode","volume":"81","author":"Du","year":"2016","journal-title":"Biosens. Bioelectron."},{"key":"10.1016\/j.talanta.2025.128257_bib3","doi-asserted-by":"crossref","first-page":"474","DOI":"10.1016\/j.jhazmat.2015.11.016","article-title":"A simple highly sensitive and selective aptamer-based colorimetric sensor for environmental toxins microcystin-LR in water samples","volume":"304","author":"Li","year":"2016","journal-title":"J. Hazard. Mater."},{"key":"10.1016\/j.talanta.2025.128257_bib4","doi-asserted-by":"crossref","DOI":"10.1016\/j.watres.2024.122119","article-title":"The biological functions of microcystins","volume":"262","author":"Wei","year":"2024","journal-title":"Water Res."},{"key":"10.1016\/j.talanta.2025.128257_bib5","doi-asserted-by":"crossref","DOI":"10.1016\/j.watres.2023.119807","article-title":"Harmful cyanobacteria-diatom\/dinoflagellate blooms and their cyanotoxins in freshwaters: a nonnegligible chronic health and ecological hazard","volume":"233","author":"Zhang","year":"2023","journal-title":"Water Res."},{"issue":"23","key":"10.1016\/j.talanta.2025.128257_bib6","doi-asserted-by":"crossref","first-page":"15940","DOI":"10.1021\/acs.est.1c05796","article-title":"Potentially poisonous plastic particles: microplastics as a vector for cyanobacterial toxins microcystin-LR and microcystin-LF","volume":"55","author":"Pestana","year":"2021","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.talanta.2025.128257_bib7","article-title":"Fabrication of graphene film composite electrochemical biosensor as a pre-screening algal toxin detection tool in the event of water contamination","volume":"8","author":"Zhang","year":"2018","journal-title":"Sci. Rep."},{"key":"10.1016\/j.talanta.2025.128257_bib8","doi-asserted-by":"crossref","DOI":"10.1016\/j.cej.2022.137413","article-title":"The removal mechanisms of microcystin-LR through electrolysis biofilters","volume":"447","author":"Ma","year":"2022","journal-title":"Chem. Eng. J."},{"key":"10.1016\/j.talanta.2025.128257_bib9","doi-asserted-by":"crossref","DOI":"10.1016\/j.chroma.2024.465139","article-title":"Self-assembled flower-like carbon nanosheets for magnetic solid-phase extraction of microcystins from aquatic organism","volume":"1730","author":"Xie","year":"2024","journal-title":"J. Chromatogr. A"},{"key":"10.1016\/j.talanta.2025.128257_bib10","doi-asserted-by":"crossref","DOI":"10.1016\/j.chroma.2024.464666","article-title":"Capillary electrophoresis tandem mass spectrometry to determine multiclass cyanotoxins in reservoir water and spinach samples","volume":"1717","author":"Carmona-Molero","year":"2024","journal-title":"J. Chromatogr. A"},{"key":"10.1016\/j.talanta.2025.128257_bib11","doi-asserted-by":"crossref","DOI":"10.1016\/j.talanta.2022.124174","article-title":"Optimization and validation of a protein phosphatase inhibition assay for accessible microcystin detection","volume":"255","author":"Alba Posse","year":"2023","journal-title":"Talanta"},{"key":"10.1016\/j.talanta.2025.128257_bib12","doi-asserted-by":"crossref","DOI":"10.1016\/j.foodchem.2024.139481","article-title":"Quantitative detection of microcystin-LR in Bellamya aeruginosa by thin-layer chromatography coupled with surface-enhanced raman spectroscopy based on in-situ ZIF-67\/Ag NPs\/Au NWs composite substrate","volume":"452","author":"Jiang","year":"2024","journal-title":"Food Chem."},{"issue":"3","key":"10.1016\/j.talanta.2025.128257_bib13","doi-asserted-by":"crossref","first-page":"900","DOI":"10.2166\/wst.2021.640","article-title":"Simplified validation of the ELISA kit determination of microcystins in surface water","volume":"85","author":"Fan","year":"2022","journal-title":"Water Sci. Technol."},{"key":"10.1016\/j.talanta.2025.128257_bib14","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1016\/j.talanta.2019.05.013","article-title":"Enzyme-free fluorescent detection of microcystin-LR using hairpin DNA-templated copper nanoclusters as signal indicator","volume":"202","author":"Zhang","year":"2019","journal-title":"Talanta"},{"key":"10.1016\/j.talanta.2025.128257_bib15","doi-asserted-by":"crossref","DOI":"10.1016\/j.snb.2024.136515","article-title":"Miniaturized photoelectrochemical sensing system for reusable detection of macromolecules and its applications for unattended environmental monitoring","volume":"421","author":"Cao","year":"2024","journal-title":"Sens. Actuators B Chem."},{"key":"10.1016\/j.talanta.2025.128257_bib16","doi-asserted-by":"crossref","DOI":"10.1016\/j.talanta.2024.127401","article-title":"Organic photoelectrochemical transistor based on titanium dioxide nanorods for detection of Microcystin-LR","volume":"285","author":"Chen","year":"2025","journal-title":"Talanta"},{"key":"10.1016\/j.talanta.2025.128257_bib17","doi-asserted-by":"crossref","DOI":"10.1016\/j.snb.2024.136437","article-title":"All in laser-induced graphene to fabricate the electrochemical biosensor for on-site detection of microcystin-LR","volume":"419","author":"Chen","year":"2024","journal-title":"Sens. Actuators B Chem."},{"key":"10.1016\/j.talanta.2025.128257_bib18","doi-asserted-by":"crossref","DOI":"10.1016\/j.talanta.2022.123495","article-title":"Colorimetric ELISA based on urease catalysis curcumin as a ratiometric indicator for the sensitive determination of aflatoxin B1 in grain products","volume":"246","author":"Dai","year":"2022","journal-title":"Talanta"},{"issue":"9","key":"10.1016\/j.talanta.2025.128257_bib19","doi-asserted-by":"crossref","first-page":"847","DOI":"10.3390\/bios13090847","article-title":"Zeolitic imidazolate framework-8 composite-based enzyme-linked aptamer assay for the sensitive detection of deoxynivalenol","volume":"13","author":"Shu","year":"2023","journal-title":"Biosensors (Basel)"},{"issue":"40","key":"10.1016\/j.talanta.2025.128257_bib20","doi-asserted-by":"crossref","first-page":"6771","DOI":"10.1039\/D4AY01184H","article-title":"Current trends in colorimetric biosensors using nanozymes for detecting biotoxins (bacterial food toxins, mycotoxins, and marine toxins)","volume":"16","author":"Feng","year":"2024","journal-title":"Anal. Methods"},{"key":"10.1016\/j.talanta.2025.128257_bib21","doi-asserted-by":"crossref","DOI":"10.1016\/j.cej.2024.150612","article-title":"Research progress of nanozymes in colorimetric biosensing: classification, activity and application","volume":"487","author":"Yang","year":"2024","journal-title":"Chem. Eng. J."},{"issue":"2","key":"10.1016\/j.talanta.2025.128257_bib22","doi-asserted-by":"crossref","first-page":"400","DOI":"10.1039\/D4QI02555E","article-title":"MOF nanozymes: active sites and sensing applications","volume":"12","author":"Zhang","year":"2024","journal-title":"Inorg. Chem. Front."},{"issue":"3","key":"10.1016\/j.talanta.2025.128257_bib23","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1039\/D2AN01850K","article-title":"Recent advances in colorimetric sensors based on nanozymes with peroxidase-like activity","volume":"148","author":"Chi","year":"2023","journal-title":"Analyst"},{"issue":"5","key":"10.1016\/j.talanta.2025.128257_bib24","doi-asserted-by":"crossref","first-page":"1416","DOI":"10.1039\/D3AN01995K","article-title":"Recent progress of metal-organic framework-based nanozymes with oxidoreductase-like activity","volume":"149","author":"Chi","year":"2024","journal-title":"Analyst"},{"key":"10.1016\/j.talanta.2025.128257_bib25","doi-asserted-by":"crossref","DOI":"10.1016\/j.microc.2024.112363","article-title":"Nanozyme based on bimetallic metal-organic frameworks and their applications: a review","volume":"208","author":"Kayani","year":"2025","journal-title":"Microchem. J."},{"issue":"51","key":"10.1016\/j.talanta.2025.128257_bib26","doi-asserted-by":"crossref","first-page":"23438","DOI":"10.1021\/jacs.2c09663","article-title":"Specific nanodrug for diabetic chronic wounds based on antioxidase-mimicking MOF-818 nanozymes","volume":"144","author":"Chao","year":"2022","journal-title":"J. Am. Chem. Soc."},{"issue":"36","key":"10.1016\/j.talanta.2025.128257_bib27","doi-asserted-by":"crossref","first-page":"15569","DOI":"10.1021\/jacs.0c07273","article-title":"Oxidase-like MOF-818 nanozyme with high specificity for catalysis of catechol oxidation","volume":"142","author":"Li","year":"2020","journal-title":"J. Am. Chem. Soc."},{"key":"10.1016\/j.talanta.2025.128257_bib28","doi-asserted-by":"crossref","DOI":"10.1016\/j.cej.2022.138321","article-title":"MOF-818 nanozyme-based colorimetric and electrochemical dual-mode smartphone sensing platform for in situ detection of H2O2 and H2S released from living cells","volume":"451","author":"Yu","year":"2023","journal-title":"Chem. Eng. J."},{"key":"10.1016\/j.talanta.2025.128257_bib29","doi-asserted-by":"crossref","DOI":"10.1016\/j.talanta.2020.121123","article-title":"MOF-818 metal-organic framework-reduced graphene oxide\/multiwalled carbon nanotubes composite for electrochemical sensitive detection of phenolic acids","volume":"218","author":"Yan","year":"2020","journal-title":"Talanta"},{"issue":"47","key":"10.1016\/j.talanta.2025.128257_bib30","doi-asserted-by":"crossref","first-page":"10303","DOI":"10.1021\/acs.jafc.5b04292","article-title":"Development and validation of a liquid chromatography-tandem mass spectrometry method for the quantitation of microcystins in blue-green algal dietary supplements","volume":"63","author":"Parker","year":"2015","journal-title":"J. Agric. Food Chem."},{"key":"10.1016\/j.talanta.2025.128257_bib31","doi-asserted-by":"crossref","DOI":"10.1016\/j.microc.2024.110559","article-title":"MOF-818(Cu)-derived bi-nanozymes of laccase and catecholase mimics and colorimetric sensing to epinephrine","volume":"201","author":"Liu","year":"2024","journal-title":"Microchem. J."},{"key":"10.1016\/j.talanta.2025.128257_bib32","doi-asserted-by":"crossref","DOI":"10.1016\/j.microc.2021.106965","article-title":"A facile nanozyme based catalytic platform for the selective and sensitive detection of thrombin","volume":"172","author":"Jiang","year":"2022","journal-title":"Microchem. J."},{"key":"10.1016\/j.talanta.2025.128257_bib33","doi-asserted-by":"crossref","DOI":"10.1016\/j.aca.2021.338899","article-title":"Synthesis of low-viscosity hydrophobic magnetic deep eutectic solvent: selective extraction of DNA","volume":"1181","author":"Peng","year":"2021","journal-title":"Anal. Chim. Acta"},{"key":"10.1016\/j.talanta.2025.128257_bib34","doi-asserted-by":"crossref","DOI":"10.1016\/j.foodchem.2023.137173","article-title":"One-pot synthesis of nano Zr-based metal-organic frameworks for fluorescence determination of quercetin and Hg2+","volume":"432","author":"Feng","year":"2024","journal-title":"Food Chem."},{"key":"10.1016\/j.talanta.2025.128257_bib35","doi-asserted-by":"crossref","DOI":"10.1016\/j.microc.2023.108852","article-title":"An electrochemical sensor based on curcumin-encapsulated zeolitic imidazolate framework-8 for the sensitive determination of aflatoxin B1 in grain products","volume":"191","author":"Dai","year":"2023","journal-title":"Microchem. J."},{"key":"10.1016\/j.talanta.2025.128257_bib36","doi-asserted-by":"crossref","DOI":"10.1016\/j.saa.2022.122192","article-title":"Traceability of bilberries (Vaccinium myrtillus L.) of the baltic-nordic region using surface-enhanced Raman spectroscopy (SERS): DFT simulation-based DNA analysis","volume":"288","author":"Vaitiekunaite","year":"2023","journal-title":"Spectroc. Acta Pt. A-Molec. Biomolec. Spectr."},{"key":"10.1016\/j.talanta.2025.128257_bib37","doi-asserted-by":"crossref","DOI":"10.1155\/2016\/8074297","article-title":"Investigation by raman spectroscopy of the decomposition process of HKUST-1 upon exposure to air","volume":"2016","author":"Todaro","year":"2016","journal-title":"J. Spectrosc."},{"key":"10.1016\/j.talanta.2025.128257_bib38","doi-asserted-by":"crossref","DOI":"10.1016\/j.cej.2021.131975","article-title":"Facile construction of a reusable multi-enzyme cascade bioreactor for effective fluorescence discrimination and quantitation of amino acid enantiomers","volume":"428","author":"Liu","year":"2022","journal-title":"Chem. Eng. J."},{"key":"10.1016\/j.talanta.2025.128257_bib39","doi-asserted-by":"crossref","DOI":"10.1016\/j.micromeso.2022.111756","article-title":"Ability evaluation of thiophenic sulfurs capture with a novel (MOF-818)-on-(Cu-BTC) composite in the presence of moisture","volume":"333","author":"Fang","year":"2022","journal-title":"Microporous Mesoporous Mater."},{"issue":"13","key":"10.1016\/j.talanta.2025.128257_bib40","doi-asserted-by":"crossref","DOI":"10.1002\/advs.202307798","article-title":"Using Cu-based metal-organic framework as a comprehensive and powerful antioxidant nanozyme for efficient osteoarthritis treatment","volume":"11","author":"Yu","year":"2024","journal-title":"Adv. Sci."},{"key":"10.1016\/j.talanta.2025.128257_bib41","doi-asserted-by":"crossref","DOI":"10.1016\/j.jhazmat.2024.135292","article-title":"Nucleobase-modulated copper nanomaterials with laccase-like activity for high-performance degradation and detection of phenolic pollutants","volume":"477","author":"Yang","year":"2024","journal-title":"J. Hazard. Mater."}],"container-title":["Talanta"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0039914025007477?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0039914025007477?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,5,11]],"date-time":"2026-05-11T04:35:49Z","timestamp":1778474149000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0039914025007477"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,12]]},"references-count":41,"alternative-id":["S0039914025007477"],"URL":"https:\/\/doi.org\/10.1016\/j.talanta.2025.128257","relation":{},"ISSN":["0039-9140"],"issn-type":[{"value":"0039-9140","type":"print"}],"subject":[],"published":{"date-parts":[[2025,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"A MOF-818-based nanozyme-linked aptasensor for microcystin-LR detection in edible algae powder","name":"articletitle","label":"Article Title"},{"value":"Talanta","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.talanta.2025.128257","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"128257"}}