{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,6]],"date-time":"2026-11-06T20:22:31Z","timestamp":1793996551583,"version":"4.8.0"},"reference-count":54,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,7,3]],"date-time":"2025-07-03T00:00:00Z","timestamp":1751500800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001698","name":"Kurita Water and Environment Foundation","doi-asserted-by":"publisher","award":["23H035"],"award-info":[{"award-number":["23H035"]}],"id":[{"id":"10.13039\/501100001698","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["JP25K01800"],"award-info":[{"award-number":["JP25K01800"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Talanta"],"published-print":{"date-parts":[[2026,1]]},"DOI":"10.1016\/j.talanta.2025.128540","type":"journal-article","created":{"date-parts":[[2025,7,3]],"date-time":"2025-07-03T10:08:54Z","timestamp":1751537334000},"page":"128540","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":5,"special_numbering":"PA","title":["Microfluidic paper-based analytical devices for antioxidant vitamins C and E in foods"],"prefix":"10.1016","volume":"297","author":[{"given":"Mana","family":"Kawahara","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kaewta","family":"Danchana","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9076-3906","authenticated-orcid":false,"given":"Takashi","family":"Kaneta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.talanta.2025.128540_bib1","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1039\/an9851000201","article-title":"Determination of ascorbic-acid in soft drinks and fruit juices. Part 1. Background correction for direct ultraviolet spectrophotometry","volume":"110","author":"Fung","year":"1985","journal-title":"Analyst"},{"key":"10.1016\/j.talanta.2025.128540_bib2","doi-asserted-by":"crossref","first-page":"889","DOI":"10.2116\/analsci.14.889","article-title":"Photometric methods for the determination of vitamin C","volume":"14","author":"Arya","year":"1998","journal-title":"Anal. Sci."},{"key":"10.1016\/j.talanta.2025.128540_bib3","doi-asserted-by":"crossref","first-page":"356","DOI":"10.1039\/an9598400356","article-title":"The determination of tocopherols in oils, foods and feeding stuffs","volume":"84","year":"1959","journal-title":"Analyst"},{"key":"10.1016\/j.talanta.2025.128540_bib4","doi-asserted-by":"crossref","first-page":"16","DOI":"10.3164\/jcbn.15-105","article-title":"Fluorescence probe for the convenient and sensitive detection of ascorbic acid","volume":"58","author":"Matsuoka","year":"2016","journal-title":"J. Clin. Biochem. Nutr."},{"key":"10.1016\/j.talanta.2025.128540_bib5","doi-asserted-by":"crossref","first-page":"530","DOI":"10.1007\/BF02532898","article-title":"Sensitive fluorometric method for tissue tocopherol analysis","volume":"11","author":"Taylor","year":"1976","journal-title":"Lipids"},{"key":"10.1016\/j.talanta.2025.128540_bib6","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1016\/j.foodchem.2014.11.104","article-title":"Comparison of UPLC and HPLC methods for determination of vitamin C","volume":"175","author":"Klimczak","year":"2015","journal-title":"Food Chem."},{"key":"10.1016\/j.talanta.2025.128540_bib7","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1016\/S0021-9673(01)01101-3","article-title":"Chromatographic analysis of \u03b1-tocopherol and related compounds in various matrices","volume":"935","author":"Ruperez","year":"2001","journal-title":"J. Chromatogr. A"},{"key":"10.1016\/j.talanta.2025.128540_bib8","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1006\/abio.1996.0127","article-title":"Gas chromatography\u2013mass spectrometry analysis of vitamin E and its oxidation products","volume":"236","author":"Liebler","year":"1996","journal-title":"Anal. Biochem."},{"key":"10.1016\/j.talanta.2025.128540_bib9","doi-asserted-by":"crossref","DOI":"10.1016\/j.ab.2025.115855","article-title":"Chitosan-stabilized copper oxide nanoparticles: a novel colorimetric approach for ascorbic acid sensing","volume":"702","author":"Kanwal","year":"2025","journal-title":"Anal. Biochem."},{"key":"10.1016\/j.talanta.2025.128540_bib10","doi-asserted-by":"crossref","first-page":"8054","DOI":"10.1021\/acsanm.5c00399","article-title":"Multiplex detection of Cd2+, Hg2+, glutathione, and ascorbic acid using NaYF4:Yb,Er@NaYF4 core\u2013shell upconversion nanoparticles and trithiocyanuric acid-modified gold nanoparticles","volume":"8","author":"Liu","year":"2025","journal-title":"ACS Appl. Nano Mater."},{"key":"10.1016\/j.talanta.2025.128540_bib11","doi-asserted-by":"crossref","DOI":"10.1016\/j.snb.2025.137399","article-title":"Dissolved oxygen-induced highly efficient chemiluminescence of acridinium sulfonamide-functionalized MnFe2O4 nanoparticles for sensitive detection of ascorbic acid","volume":"431","author":"Hu","year":"2025","journal-title":"Sensor. Actuator. B Chem."},{"key":"10.1016\/j.talanta.2025.128540_bib12","doi-asserted-by":"crossref","first-page":"766","DOI":"10.1007\/s00604-024-06852-w","article-title":"Integrated tetrahydroxyphthalocyanine-coated graphene decorated with ionic liquid-functionalized gold nanoparticles for highly sensitive and selective electrochemical determination of ascorbic acid in fruit juices","volume":"191","author":"Mei","year":"2024","journal-title":"Mikrochim. Acta"},{"key":"10.1016\/j.talanta.2025.128540_bib13","doi-asserted-by":"crossref","DOI":"10.1016\/j.ab.2019.113415","article-title":"Review on nanomaterials-enabled electrochemical sensors for ascorbic acid detection","volume":"586","author":"Dhara","year":"2019","journal-title":"Anal. Biochem."},{"key":"10.1016\/j.talanta.2025.128540_bib14","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1016\/S0021-9673(00)00314-9","article-title":"Automated analysis of vitamin E isomers in vegetable oils by continuous membrane extraction and liquid chromatography-electrochemical detection","volume":"881","author":"S\u00e1nchez-P\u00e9rez","year":"2000","journal-title":"J. Chromatogr. A"},{"key":"10.1016\/j.talanta.2025.128540_bib15","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1016\/S0021-9673(01)00991-8","article-title":"Analysis of vitamin E isomers in seeds and nuts with and without coupled hydrolysis by liquid chromatography and coulometric detection","volume":"935","author":"Delgado-Zamarre\u00f1o","year":"2001","journal-title":"J. Chromatogr. A"},{"key":"10.1016\/j.talanta.2025.128540_bib16","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1016\/S0039-9140(96)02041-3","article-title":"Determination of vitamin E (alpha-tocopherol) using copper(II)-neocuproine reagent","volume":"44","author":"Tutem","year":"1997","journal-title":"Talanta"},{"key":"10.1016\/j.talanta.2025.128540_bib17","doi-asserted-by":"crossref","first-page":"1318","DOI":"10.1002\/anie.200603817","article-title":"Patterned paper as a platform for inexpensive, low-volume, portable bioassays","volume":"46","author":"Martinez","year":"2007","journal-title":"Angew. Chem., Int. Ed."},{"key":"10.1016\/j.talanta.2025.128540_bib18","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1016\/j.microc.2018.06.005","article-title":"Paper based analytical device modified with nanoporous material for the fluorescent sensing of gliadin content in different food samples","volume":"142","author":"Mar\u00edn-Barroso","year":"2018","journal-title":"Microchem. J."},{"key":"10.1016\/j.talanta.2025.128540_bib19","doi-asserted-by":"crossref","first-page":"44","DOI":"10.3390\/chemosensors7030044","article-title":"One-step polylactic acid screen-printing microfluidic paper-based analytical device: application for simultaneous detection of nitrite and nitrate in food samples","volume":"7","author":"Teepoo","year":"2019","journal-title":"Chemosensors"},{"key":"10.1016\/j.talanta.2025.128540_bib20","doi-asserted-by":"crossref","DOI":"10.1016\/j.microc.2020.105412","article-title":"An environmentally friendly microfluidic paper-based analytical device for simultaneous colorimetric detection of nitrite and nitrate in food products","volume":"159","author":"Thongkam","year":"2020","journal-title":"Microchem. J."},{"key":"10.1016\/j.talanta.2025.128540_bib21","doi-asserted-by":"crossref","DOI":"10.1016\/j.aca.2024.342417","article-title":"A novel premixing strategy for highly sensitive detection of nitrite on paper-based analytical devices","volume":"1299","author":"Xu","year":"2024","journal-title":"Anal. Chim. Acta"},{"key":"10.1016\/j.talanta.2025.128540_bib22","article-title":"A colorimetric microfluidic paper-based analytical device for sulfonamides in cow milk using enzymatic inhibition","volume":"356","author":"Sousa","year":"2021","journal-title":"Food Chem."},{"key":"10.1016\/j.talanta.2025.128540_bib23","doi-asserted-by":"crossref","DOI":"10.1016\/j.foodchem.2021.129548","article-title":"Paper-based analytical device for high-throughput monitoring tetracycline residue in milk","volume":"354","author":"Lu","year":"2021","journal-title":"Food Chem."},{"key":"10.1016\/j.talanta.2025.128540_bib24","doi-asserted-by":"crossref","first-page":"689","DOI":"10.1039\/D1AY02065J","article-title":"An origami paper-based analytical device for rapid detection of testosterone in healthcare food","volume":"14","author":"Li","year":"2022","journal-title":"Anal. Methods"},{"key":"10.1016\/j.talanta.2025.128540_bib25","doi-asserted-by":"crossref","first-page":"13","DOI":"10.3390\/mi13010013","article-title":"An origami paper-based analytical device for rapid and sensitive analysis of acrylamide in foods","volume":"13","author":"Yan","year":"2022","journal-title":"Micromachines"},{"key":"10.1016\/j.talanta.2025.128540_bib26","article-title":"Digital colorimetric sensor for assessment of iodate in food-grade salt based on paper-based analytical device","volume":"414","year":"2023","journal-title":"Food Chem."},{"key":"10.1016\/j.talanta.2025.128540_bib27","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1007\/s42452-024-06000-2","article-title":"Hybrid photo paper-based microfluidic device for colorimetric detection of iodine in salt","volume":"6","author":"Chong","year":"2024","journal-title":"Discov. Appl. Sci."},{"key":"10.1016\/j.talanta.2025.128540_bib28","doi-asserted-by":"crossref","DOI":"10.1016\/j.talanta.2022.123242","article-title":"Detection and discrimination of antibiotics in food samples using a microfluidic paper-based optical tongue","volume":"241","author":"Taghizadeh-Behbahani","year":"2022","journal-title":"Talanta"},{"key":"10.1016\/j.talanta.2025.128540_bib29","doi-asserted-by":"crossref","first-page":"1194","DOI":"10.1021\/acssensors.2c00300","article-title":"Dip-and-read, organic-solvent-compatible, paper-based analytical devices equipped with chromatographic separation for indole analysis in shrimp","volume":"7","author":"Seetasang","year":"2022","journal-title":"ACS Sens."},{"key":"10.1016\/j.talanta.2025.128540_bib30","doi-asserted-by":"crossref","DOI":"10.1016\/j.microc.2022.107513","article-title":"Determination of glutamate using paper-based microfluidic devices with colorimetric detection for food samples","volume":"179","author":"Danchana","year":"2022","journal-title":"Microchem. J."},{"key":"10.1016\/j.talanta.2025.128540_bib31","doi-asserted-by":"crossref","first-page":"86","DOI":"10.3390\/mi7050086","article-title":"Advances in microfluidic paper-based analytical devices for food and water analysis","volume":"7","author":"Busa","year":"2016","journal-title":"Micromachines"},{"key":"10.1016\/j.talanta.2025.128540_bib32","doi-asserted-by":"crossref","first-page":"32","DOI":"10.3390\/mi9010032","article-title":"Detecting chemical hazards in foods using microfluidic paper-based analytical devices (\u03bcPADs): the real-world application","volume":"9","author":"Hua","year":"2018","journal-title":"Micromachines"},{"key":"10.1016\/j.talanta.2025.128540_bib33","doi-asserted-by":"crossref","first-page":"8188","DOI":"10.1021\/acs.jafc.2c02366","article-title":"Microfluidic paper-based analytical devices for the determination of food contaminants: developments and applications","volume":"70","author":"Wang","year":"2022","journal-title":"J. Agric. Food Chem."},{"key":"10.1016\/j.talanta.2025.128540_bib34","doi-asserted-by":"crossref","DOI":"10.1016\/j.foodcont.2022.108885","article-title":"Advances in microfluidic analysis of residual antibiotics in food","volume":"136","author":"Jin","year":"2022","journal-title":"Food Control"},{"key":"10.1016\/j.talanta.2025.128540_bib35","doi-asserted-by":"crossref","DOI":"10.1016\/j.trac.2024.118012","article-title":"Innovative and cutting-edge approaches in microfluidic paper-based analytical devices for detection of food adulteration","volume":"181","author":"Alahmad","year":"2024","journal-title":"Trends Anal. Chem."},{"key":"10.1016\/j.talanta.2025.128540_bib36","doi-asserted-by":"crossref","first-page":"1094","DOI":"10.1021\/acssensors.0c02367","article-title":"Dip-type paper-based analytical device for straightforward quantitative detection without precise sample introduction","volume":"6","author":"Komatsu","year":"2021","journal-title":"ACS Sens."},{"key":"10.1016\/j.talanta.2025.128540_bib37","doi-asserted-by":"crossref","first-page":"11213","DOI":"10.1021\/acsomega.2c08138","article-title":"Development of pipetteless paper-based analytical devices with a volume gauge","volume":"8","author":"Danchana","year":"2023","journal-title":"ACS Omega"},{"key":"10.1016\/j.talanta.2025.128540_bib38","doi-asserted-by":"crossref","first-page":"1162","DOI":"10.1021\/ac902647r","article-title":"Electrochemical detection in a paper-based separation device","volume":"82","author":"Carvalhal","year":"2010","journal-title":"Anal. Chem."},{"key":"10.1016\/j.talanta.2025.128540_bib39","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.aca.2012.07.003","article-title":"Sodium dodecyl sulfate-modified electrochemical paper-based analytical device for determination of dopamine levels in biological samples","volume":"744","author":"Rattanarata","year":"2012","journal-title":"Anal. Chim. Acta"},{"key":"10.1016\/j.talanta.2025.128540_bib40","doi-asserted-by":"crossref","first-page":"91","DOI":"10.2116\/analsci.34.91","article-title":"Determination of ascorbic acid in commercial tablets using pencil drawn electrochemical paper-based analytical devices","volume":"34","author":"Oliveira","year":"2018","journal-title":"Anal. Sci."},{"key":"10.1016\/j.talanta.2025.128540_bib41","doi-asserted-by":"crossref","DOI":"10.1016\/j.talanta.2022.123812","article-title":"Silicone glue-based graphite ink incorporated on paper platform as an affordable approach to construct stable electrochemical sensors","volume":"251","author":"Castro","year":"2023","journal-title":"Talanta"},{"key":"10.1016\/j.talanta.2025.128540_bib42","doi-asserted-by":"crossref","first-page":"3050","DOI":"10.1021\/acs.jchemed.1c00100","article-title":"Using a paper-based analytical device designed for remote learning environments to achieve simple quantitative colorimetry without micropipettes","volume":"98","author":"Komatsu","year":"2021","journal-title":"J. Chem. Educ."},{"key":"10.1016\/j.talanta.2025.128540_bib43","doi-asserted-by":"crossref","first-page":"57084","DOI":"10.1021\/acsami.1c14435","article-title":"Fully inkjet printing preparation of a carbon dots multichannel microfluidic paper-based sensor and its application in food additive detection","volume":"13","author":"Deng","year":"2021","journal-title":"ACS Appl. Mater. Interfaces"},{"key":"10.1016\/j.talanta.2025.128540_bib44","doi-asserted-by":"crossref","DOI":"10.1016\/j.microc.2021.106054","article-title":"On-site microfluidic paper- based titration device for rapid semi-quantitative vitamin C content in beverages","volume":"164","author":"Kaewchuay","year":"2021","journal-title":"Microchem. J."},{"key":"10.1016\/j.talanta.2025.128540_bib45","doi-asserted-by":"crossref","first-page":"15704","DOI":"10.1039\/D3RA01601C","article-title":"Accuracy improvement via novel ratiometry design in distance-based microfluidic paper based analytical device: instrument-free point of care testing","volume":"13","author":"Al-Jaf","year":"2023","journal-title":"RSC Adv."},{"key":"10.1016\/j.talanta.2025.128540_bib46","doi-asserted-by":"crossref","first-page":"10454","DOI":"10.1021\/acs.analchem.7b02521","article-title":"Digitally controlled procedure for assembling fully drawn paper-based electroanalytical platforms","volume":"89","author":"Dossi","year":"2017","journal-title":"Anal. Chem."},{"key":"10.1016\/j.talanta.2025.128540_bib47","doi-asserted-by":"crossref","DOI":"10.1016\/j.microc.2022.107588","article-title":"Electrochemical paper-based analytical devices containing magnetite nanoparticles for the determination of vitamins B2 and B6","volume":"179","author":"Pereira","year":"2022","journal-title":"Microchem. J."},{"key":"10.1016\/j.talanta.2025.128540_bib48","doi-asserted-by":"crossref","first-page":"1639","DOI":"10.4155\/bio-2018-0136","article-title":"Paper-based microfluidic device for diagnosis of osteoporosis markers","volume":"10","author":"Yerrapragada","year":"2018","journal-title":"Bioanalysis"},{"key":"10.1016\/j.talanta.2025.128540_bib49","first-page":"518","article-title":"Spectrophotometric determination of ascorbic acid in canned fruit juices, cordials, and soft drinks with iron(III) and 1,10-phenanthroline as reagents","volume":"70","author":"Lau","year":"1987","journal-title":"J. Assoc. Off. Anal. Chem."},{"key":"10.1016\/j.talanta.2025.128540_bib50","first-page":"1289","article-title":"A rapid and sensitive method for the determination of ascorbic acid using 4,7-diphenyl-l,10-phenanthroline","volume":"45","author":"Arakawa","year":"1981","journal-title":"Agric. Biol. Chem."},{"key":"10.1016\/j.talanta.2025.128540_bib51","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1016\/0006-3002(59)90522-0","article-title":"Proteolytic enzyme of actinidia chinensis","volume":"33","author":"Arcus","year":"1959","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.talanta.2025.128540_bib52","doi-asserted-by":"crossref","first-page":"581","DOI":"10.3177\/jnsv.43.581","article-title":"Enzymatic properties, substrate specificities and pH-activity profiles of two kiwifruit proteases","volume":"43","author":"Sugiyama","year":"1997","journal-title":"J. Nutr. Sci. Vitaminol."},{"key":"10.1016\/j.talanta.2025.128540_bib53","doi-asserted-by":"crossref","first-page":"1199","DOI":"10.1080\/1071576021000016463","article-title":"Interactions of flavonoids with iron and copper ions: a mechanism for their antioxidant activity","volume":"36","author":"Mira","year":"2002","journal-title":"Free Radic. Res."},{"key":"10.1016\/j.talanta.2025.128540_bib54","first-page":"1215","article-title":"Determination of tocopherols (vitamin E) by reduction of cupric ion","volume":"65","author":"Contreras-Guzm\u00e1n","year":"1982","journal-title":"Assoc. Off. Anal. Chem."}],"container-title":["Talanta"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0039914025010306?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0039914025010306?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T04:47:55Z","timestamp":1762490875000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0039914025010306"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1]]},"references-count":54,"alternative-id":["S0039914025010306"],"URL":"https:\/\/doi.org\/10.1016\/j.talanta.2025.128540","relation":{},"ISSN":["0039-9140"],"issn-type":[{"value":"0039-9140","type":"print"}],"subject":[],"published":{"date-parts":[[2026,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Microfluidic paper-based analytical devices for antioxidant vitamins C and E in foods","name":"articletitle","label":"Article Title"},{"value":"Talanta","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.talanta.2025.128540","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Authors. Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"128540"}}