{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T00:23:44Z","timestamp":1791332624503,"version":"4.3.1"},"reference-count":61,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,1,17]],"date-time":"2026-01-17T00:00:00Z","timestamp":1768608000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100009604","name":"Changchun Science and Technology Bureau","doi-asserted-by":"publisher","award":["2024GZZ14"],"award-info":[{"award-number":["2024GZZ14"]}],"id":[{"id":"10.13039\/501100009604","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["22377122"],"award-info":[{"award-number":["22377122"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["U22A20183"],"award-info":[{"award-number":["U22A20183"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002367","name":"Chinese Academy of Sciences","doi-asserted-by":"publisher","award":["029GJHZ2024038FN"],"award-info":[{"award-number":["029GJHZ2024038FN"]}],"id":[{"id":"10.13039\/501100002367","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100011789","name":"Department of Science and Technology of Jilin Province","doi-asserted-by":"publisher","award":["20250203023SF"],"award-info":[{"award-number":["20250203023SF"]}],"id":[{"id":"10.13039\/501100011789","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Talanta"],"published-print":{"date-parts":[[2026,4]]},"DOI":"10.1016\/j.talanta.2025.129267","type":"journal-article","created":{"date-parts":[[2025,12,16]],"date-time":"2025-12-16T07:41:16Z","timestamp":1765870876000},"page":"129267","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"special_numbering":"C","title":["An electrochemical sensing platform for early prediction of dental caries"],"prefix":"10.1016","volume":"300","author":[{"given":"Ze","family":"Li","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hao","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoyan","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guanghong","family":"Han","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcin","family":"Karbarz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"HongDa","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qiang","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.talanta.2025.129267_bib1","doi-asserted-by":"crossref","first-page":"1909","DOI":"10.1016\/S0140-6736(22)02322-4","article-title":"WHO calls to end the global crisis of oral health","volume":"400","author":"Benzian","year":"2022","journal-title":"Lancet"},{"key":"10.1016\/j.talanta.2025.129267_bib2","doi-asserted-by":"crossref","first-page":"422","DOI":"10.1111\/ipd.12483","article-title":"Dental caries lesions in primary teeth without obvious cavitation: treatment decision-making process","volume":"29","author":"Leal","year":"2019","journal-title":"Int. J. Paediatr. Dent."},{"issue":"Suppl 1","key":"10.1016\/j.talanta.2025.129267_bib3","doi-asserted-by":"crossref","first-page":"S3","DOI":"10.1186\/1472-6831-15-S1-S3","article-title":"Detection and diagnosis of the early caries lesion","volume":"15","author":"Gomez","year":"2015","journal-title":"BMC Oral Health"},{"key":"10.1016\/j.talanta.2025.129267_bib4","doi-asserted-by":"crossref","first-page":"117","DOI":"10.5644\/ama2006-124.80","article-title":"Dental caries: strategies to control this preventable disease","volume":"42","author":"Rugg-Gunn","year":"2013","journal-title":"Acta. Med. Acad."},{"key":"10.1016\/j.talanta.2025.129267_bib5","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1016\/j.cden.2010.03.002","article-title":"Microbiology of dental plaque biofilms and their role in oral health and caries","volume":"54","author":"Marsh","year":"2010","journal-title":"Dent Clin North Am"},{"key":"10.1016\/j.talanta.2025.129267_bib6","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1038\/s41579-023-00963-6","article-title":"The oral microbiome: diversity, biogeography and human health","volume":"22","author":"Baker","year":"2024","journal-title":"Nat. Rev. Microbiol."},{"key":"10.1016\/j.talanta.2025.129267_bib7","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1111\/j.1399-302X.2005.00253.x","article-title":"Effect of mixed mutans streptococci colonization on caries development","volume":"21","author":"Seki","year":"2006","journal-title":"Oral Microbiol. Immunol."},{"key":"10.1016\/j.talanta.2025.129267_bib8","doi-asserted-by":"crossref","first-page":"294","DOI":"10.1177\/0022034510379602","article-title":"The role of bacteria in the caries process: ecological perspectives","volume":"90","author":"Takahashi","year":"2011","journal-title":"J. Dent. Res."},{"key":"10.1016\/j.talanta.2025.129267_bib9","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1038\/s41368-022-00167-3","article-title":"Expert consensus on dental caries management","volume":"14","author":"Cheng","year":"2022","journal-title":"Int. J. Oral Sci."},{"key":"10.1016\/j.talanta.2025.129267_bib10","article-title":"Association of polymicrobial interactions with dental caries development and prevention","volume":"14","author":"Zhu","year":"2023","journal-title":"Front. Microbiol."},{"key":"10.1016\/j.talanta.2025.129267_bib11","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1016\/S0065-2911(00)42004-7","article-title":"Adaptation of oral streptococci to low pH","volume":"42","author":"Quivey","year":"2000","journal-title":"Adv. Microb. Physiol."},{"key":"10.1016\/j.talanta.2025.129267_bib12","doi-asserted-by":"crossref","first-page":"486","DOI":"10.1159\/000016628","article-title":"Strain-related acid production by oral streptococci","volume":"34","author":"de Soet","year":"2000","journal-title":"Caries Res."},{"key":"10.1016\/j.talanta.2025.129267_bib13","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/nrdp.2017.30","article-title":"Dental caries","volume":"3","author":"Pitts","year":"2017","journal-title":"Nat. Rev. Dis. Primers"},{"key":"10.1016\/j.talanta.2025.129267_bib14","first-page":"67","article-title":"Sequence of ultrastructural changes of enamel crystals and Streptococcus mutans biofilm in early enamel caries in vitro","volume":"49","author":"Hashizume","year":"2002","journal-title":"J. Med. Dent. Sci."},{"key":"10.1016\/j.talanta.2025.129267_bib15","doi-asserted-by":"crossref","first-page":"6969","DOI":"10.7150\/thno.100600","article-title":"Salivary diagnostics: opportunities and challenges","volume":"14","author":"Li","year":"2024","journal-title":"Theranostics"},{"key":"10.1016\/j.talanta.2025.129267_bib16","doi-asserted-by":"crossref","first-page":"e1","DOI":"10.1038\/ijos.2017.35","article-title":"Salivary proteins and microbiota as biomarkers for early childhood caries risk assessment","volume":"9","author":"Hemadi","year":"2017","journal-title":"Int. J. Oral Sci."},{"key":"10.1016\/j.talanta.2025.129267_bib17","first-page":"42","article-title":"Cariogenic oral flora and its relation to dental caries","volume":"67","author":"Llena-Puy","year":"2000","journal-title":"ASDC J Dent Child"},{"key":"10.1016\/j.talanta.2025.129267_bib18","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1177\/00220345241297583","article-title":"The healthy oral microbiome: a changing ecosystem throughout the human lifespan","volume":"104","author":"Corr\u00eaa","year":"2025","journal-title":"J. Dent. Res."},{"key":"10.1016\/j.talanta.2025.129267_bib19","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1177\/0022034511415415","article-title":"Gene regulation in S. mutans: complex control in a complex environment","volume":"91","author":"Smith","year":"2012","journal-title":"J. Dent. Res."},{"key":"10.1016\/j.talanta.2025.129267_bib20","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1111\/prd.12100","article-title":"Salivary biomarkers for dental caries","volume":"70","author":"Gao","year":"2016","journal-title":"Periodontol"},{"key":"10.1016\/j.talanta.2025.129267_bib21","doi-asserted-by":"crossref","DOI":"10.1016\/j.bios.2020.112723","article-title":"Recent advances in graphene-based nanobiosensors for salivary biomarker detection","volume":"171","author":"Goldoni","year":"2021","journal-title":"Biosens. Bioelectron."},{"key":"10.1016\/j.talanta.2025.129267_bib22","first-page":"199","article-title":"Comparison of real-time quantitative PCR with a chairside test for Streptococcus Mutans assessment","volume":"20","author":"Li","year":"2017","journal-title":"Chin. J. Dent. Res."},{"key":"10.1016\/j.talanta.2025.129267_bib23","doi-asserted-by":"crossref","first-page":"1101","DOI":"10.4014\/jmb.2304.04026","article-title":"Rapid detection of Streptococcus mutans using an integrated microfluidic system with loop-mediated isothermal amplification","volume":"33","author":"Wang","year":"2023","journal-title":"J. Microbiol. Biotechnol."},{"key":"10.1016\/j.talanta.2025.129267_bib24","doi-asserted-by":"crossref","first-page":"74","DOI":"10.3390\/dj9070074","article-title":"Autofluorescence detection method for dental plaque bacteria detection and classification: example of Porphyromonas gingivalis, Aggregatibacter actinomycetemcomitans, and Streptococcus mutans","volume":"9","author":"Yan","year":"2021","journal-title":"Dent. J."},{"key":"10.1016\/j.talanta.2025.129267_bib25","doi-asserted-by":"crossref","first-page":"1339","DOI":"10.1111\/j.1365-2672.2006.02877.x","article-title":"Comparison of culture media and chairside assays for enumerating mutans streptococci","volume":"100","author":"Hildebrandt","year":"2006","journal-title":"J. Appl. Microbiol."},{"key":"10.1016\/j.talanta.2025.129267_bib26","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1016\/S0167-7012(02)00106-9","article-title":"Checkerboard DNA-DNA hybridisation technology focused on the analysis of Gram-positive cariogenic bacteria","volume":"51","author":"Wall-Manning","year":"2002","journal-title":"J. Microbiol. Methods"},{"key":"10.1016\/j.talanta.2025.129267_bib27","first-page":"283","article-title":"Association of salivary Streptococcus mutans levels determined by rapid detection system using monoclonal antibodies with prevalence of root surface caries","volume":"21","author":"Ikebe","year":"2008","journal-title":"Am. J. Dent."},{"key":"10.1016\/j.talanta.2025.129267_bib28","doi-asserted-by":"crossref","first-page":"5719","DOI":"10.1007\/s00784-023-05206-9","article-title":"Sensors for in situ monitoring of oral and dental health parameters in saliva","volume":"27","author":"Timpel","year":"2023","journal-title":"Clin. Oral Invest."},{"key":"10.1016\/j.talanta.2025.129267_bib29","doi-asserted-by":"crossref","DOI":"10.1016\/j.aca.2022.339589","article-title":"Real-time monitoring of the pH microenvironment at the interface of multispecies biofilm and dental composites","volume":"1201","author":"Nguyen","year":"2022","journal-title":"Anal. Chim. Acta"},{"key":"10.1016\/j.talanta.2025.129267_bib30","doi-asserted-by":"crossref","DOI":"10.1016\/j.aca.2024.343042","article-title":"Triple-function carbon-based Ca2+ ion-selective pH ring microelectrode to study real-time bacteria-mediated hydroxyapatite corrosion","volume":"1321","author":"Sheet","year":"2024","journal-title":"Anal. Chim. Acta"},{"key":"10.1016\/j.talanta.2025.129267_bib31","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1159\/000315273","article-title":"The \u201cstrip method\u201d: a simple method for plaque pH assessment","volume":"44","author":"Carl\u00e9n","year":"2010","journal-title":"Caries Res."},{"key":"10.1016\/j.talanta.2025.129267_bib32","first-page":"1","article-title":"Advances in electrochemical biosensors for the detection of common oral diseases","author":"Liu","year":"2024","journal-title":"Crit. Rev. Anal. Chem."},{"key":"10.1016\/j.talanta.2025.129267_bib33","doi-asserted-by":"crossref","first-page":"1246","DOI":"10.1016\/j.ijbiomac.2018.11.277","article-title":"Bioassay of saliva proteins: the best alternative for conventional methods in non-invasive diagnosis of cancer","volume":"124","author":"Eftekhari","year":"2019","journal-title":"Int. J. Biol. Macromol."},{"key":"10.1016\/j.talanta.2025.129267_bib34","first-page":"1","article-title":"Biomolecular sensors for advanced physiological monitoring","author":"Flynn","year":"2023","journal-title":"Nat. Rev. Bioeng."},{"key":"10.1016\/j.talanta.2025.129267_bib35","doi-asserted-by":"crossref","first-page":"346","DOI":"10.1038\/s44222-023-00032-w","article-title":"Device integration of electrochemical biosensors","volume":"1","author":"Wu","year":"2023","journal-title":"Nat. Rev. Bioeng."},{"key":"10.1016\/j.talanta.2025.129267_bib36","doi-asserted-by":"crossref","first-page":"2386","DOI":"10.3390\/microorganisms10122386","article-title":"Exploiting conserved quorum sensing signals in Streptococcus mutans and Streptococcus pneumoniae","volume":"10","author":"Bernab\u00e8","year":"2022","journal-title":"Microorganisms"},{"key":"10.1016\/j.talanta.2025.129267_bib37","doi-asserted-by":"crossref","first-page":"1385","DOI":"10.1021\/acsinfecdis.8b00115","article-title":"Structure-activity relationships of the competence stimulating peptide in Streptococcus mutans reveal motifs critical for membrane protease SepM recognition and ComD receptor activation","volume":"4","author":"Bikash","year":"2018","journal-title":"ACS Infect. Dis."},{"key":"10.1016\/j.talanta.2025.129267_bib38","doi-asserted-by":"crossref","first-page":"730","DOI":"10.1186\/s12903-024-04436-x","article-title":"SepM mutation in Streptococcus mutans clinical isolates and related function analysis","volume":"24","author":"Liu","year":"2024","journal-title":"BMC Oral Health"},{"key":"10.1016\/j.talanta.2025.129267_bib39","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1016\/j.bioelechem.2019.04.014","article-title":"A novel molecularly imprinted electrochemical sensor based on double sensitization by MOF\/CNTs and Prussian blue for detection of 17\u03b2-estradiol","volume":"129","author":"Duan","year":"2019","journal-title":"Bioelectrochemistry"},{"key":"10.1016\/j.talanta.2025.129267_bib40","doi-asserted-by":"crossref","DOI":"10.1016\/j.talanta.2023.125394","article-title":"Disease diagnosis and application analysis of molecularly imprinted polymers (MIPs) in saliva detection","volume":"269","author":"Li","year":"2024","journal-title":"Talanta"},{"key":"10.1016\/j.talanta.2025.129267_bib41","doi-asserted-by":"crossref","first-page":"996","DOI":"10.3390\/s20040996","article-title":"Molecularly imprinted polymers and surface imprinted polymers based electrochemical biosensor for infectious diseases","volume":"20","author":"Cui","year":"2020","journal-title":"Sensors (Basel)"},{"key":"10.1016\/j.talanta.2025.129267_bib42","doi-asserted-by":"crossref","first-page":"3446","DOI":"10.1128\/AAC.00342-11","article-title":"Selective membrane disruption: mode of action of C16G2, a specifically targeted antimicrobial peptide","volume":"55","author":"Kaplan","year":"2011","journal-title":"Antimicrob. Agents Chemother."},{"key":"10.1016\/j.talanta.2025.129267_bib43","doi-asserted-by":"crossref","first-page":"1282","DOI":"10.3390\/s22031282","article-title":"Electrochemically deposited molecularly imprinted polymer-based sensors","volume":"22","author":"Ramanavi\u010dius","year":"2022","journal-title":"Sensors (Basel)"},{"key":"10.1016\/j.talanta.2025.129267_bib44","doi-asserted-by":"crossref","first-page":"3275","DOI":"10.1016\/S0006-3495(01)75961-9","article-title":"Transport properties of the calcium ionophore ETH-129","volume":"81","author":"Wang","year":"2001","journal-title":"Biophys. J."},{"key":"10.1016\/j.talanta.2025.129267_bib45","doi-asserted-by":"crossref","first-page":"35078","DOI":"10.1039\/D3RA07212F","article-title":"Metal-organic framework (UiO-66 and UiO-66-NH2)-based adsorbents for bilirubin removal used in hemoperfusion","volume":"13","author":"Liu","year":"2023","journal-title":"RSC Adv."},{"key":"10.1016\/j.talanta.2025.129267_bib46","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1007\/s00604-020-04673-1","article-title":"Electrochemical sensor based on Prussian blue\/multi-walled carbon nanotubes functionalized polypyrrole nanowire arrays for hydrogen peroxide and microRNA detection","volume":"188","author":"Yang","year":"2021","journal-title":"Mikrochim. Acta"},{"key":"10.1016\/j.talanta.2025.129267_bib47","doi-asserted-by":"crossref","DOI":"10.3389\/fcimb.2023.1116021","article-title":"The effect of argon cold atmospheric plasma on the metabolism and demineralization of oral plaque biofilms","volume":"13","author":"Zhao","year":"2023","journal-title":"Front. Cell. Infect. Microbiol."},{"key":"10.1016\/j.talanta.2025.129267_bib48","doi-asserted-by":"crossref","first-page":"9061","DOI":"10.1039\/C9CP00548J","article-title":"Theory of cyclic voltammetry in random arrays of cylindrical microelectrodes applied to carbon felt electrodes for vanadium redox flow batteries","volume":"21","author":"Tichter","year":"2019","journal-title":"Phys. Chem. Chem. Phys."},{"key":"10.1016\/j.talanta.2025.129267_bib49","doi-asserted-by":"crossref","first-page":"2573","DOI":"10.1021\/cr030727g","article-title":"Homogeneous versus heterogeneous self-exchange electron transfer reactions of metal complexes: insights from pressure effects","volume":"105","author":"Swaddle","year":"2005","journal-title":"Chem. Rev."},{"key":"10.1016\/j.talanta.2025.129267_bib50","doi-asserted-by":"crossref","first-page":"811","DOI":"10.1016\/j.bmcl.2019.01.029","article-title":"Identification of highly potent competence stimulating peptide-based quorum sensing activators in Streptococcus mutans through the utilization of N-methyl and reverse alanine scanning","volume":"29","author":"Bikash","year":"2019","journal-title":"Bioorg. Med. Chem. Lett"},{"key":"10.1016\/j.talanta.2025.129267_bib51","doi-asserted-by":"crossref","first-page":"1597","DOI":"10.3390\/polym15071597","article-title":"Towards electrochemical sensor based on molecularly imprinted polypyrrole for the detection of bacteria-listeria monocytogenes","volume":"15","author":"Liustrovaite","year":"2023","journal-title":"Polymers (Basel)"},{"key":"10.1016\/j.talanta.2025.129267_bib52","doi-asserted-by":"crossref","first-page":"9780","DOI":"10.1021\/acs.analchem.3c05112","article-title":"Portable saliva sensor based on dual recognition elements for detection of caries pathogenic bacteria","volume":"96","author":"Li","year":"2024","journal-title":"Anal. Chem."},{"key":"10.1016\/j.talanta.2025.129267_bib53","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1038\/ijos.2016.38","article-title":"Saliva in the diagnosis of diseases","volume":"8","author":"Zhang","year":"2016","journal-title":"Int. J. Oral Sci."},{"key":"10.1016\/j.talanta.2025.129267_bib54","doi-asserted-by":"crossref","first-page":"350","DOI":"10.1016\/j.talanta.2017.11.004","article-title":"Specific chemiluminescent protocol for dual-site recognition of Streptococcus mutans utilizing strong affinity between teicoplanin and Gram-positive bacteria","volume":"179","author":"Su","year":"2018","journal-title":"Talanta"},{"key":"10.1016\/j.talanta.2025.129267_bib55","doi-asserted-by":"crossref","first-page":"30640","DOI":"10.1021\/acsami.9b10718","article-title":"Engineering DNA-nanozyme interfaces for rapid detection of dental bacteria","volume":"11","author":"Zhang","year":"2019","journal-title":"ACS Appl. Mater. Interfaces"},{"key":"10.1016\/j.talanta.2025.129267_bib56","doi-asserted-by":"crossref","first-page":"4493","DOI":"10.3390\/s18124493","article-title":"Versatile Protein-A coated photoelectric immunosensors with a purple-membrane monolayer transducer fabricated by affinity-immobilization on a graphene-oxide complexed linker and by shear flow","volume":"18","author":"Wu","year":"2018","journal-title":"Sensors (Basel)"},{"key":"10.1016\/j.talanta.2025.129267_bib57","doi-asserted-by":"crossref","first-page":"63","DOI":"10.3390\/bios8030063","article-title":"Lectin- and saccharide-functionalized nano-chemiresistor arrays for detection and identification of pathogenic bacteria infection","volume":"8","author":"Saucedo","year":"2018","journal-title":"Biosensors (Basel)"},{"key":"10.1016\/j.talanta.2025.129267_bib58","doi-asserted-by":"crossref","first-page":"575","DOI":"10.3390\/mi10090575","article-title":"Label-free electrochemical detection of S. mutans exploiting commercially fabricated printed circuit board sensing electrodes","volume":"10","author":"Dutta","year":"2019","journal-title":"Micromachines (Basel)"},{"key":"10.1016\/j.talanta.2025.129267_bib59","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1177\/2211068213495207","article-title":"Rapid, electrical impedance detection of bacterial pathogens using immobilized antimicrobial peptides","volume":"19","author":"Lillehoj","year":"2014","journal-title":"J. Lab. Autom."},{"key":"10.1016\/j.talanta.2025.129267_bib60","article-title":"The oral microbiota: community composition, influencing factors, pathogenesis, and interventions","volume":"13","author":"Li","year":"2022","journal-title":"Front. Microbiol."},{"key":"10.1016\/j.talanta.2025.129267_bib61","doi-asserted-by":"crossref","first-page":"745","DOI":"10.1038\/s41579-018-0089-x","article-title":"The oral microbiota: dynamic communities and host interactions","volume":"16","author":"Lamont","year":"2018","journal-title":"Nat. Rev. Microbiol."}],"container-title":["Talanta"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0039914025017588?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0039914025017588?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,6,12]],"date-time":"2026-06-12T08:48:49Z","timestamp":1781254129000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0039914025017588"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,4]]},"references-count":61,"alternative-id":["S0039914025017588"],"URL":"https:\/\/doi.org\/10.1016\/j.talanta.2025.129267","relation":{},"ISSN":["0039-9140"],"issn-type":[{"value":"0039-9140","type":"print"}],"subject":[],"published":{"date-parts":[[2026,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"An electrochemical sensing platform for early prediction of dental caries","name":"articletitle","label":"Article Title"},{"value":"Talanta","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.talanta.2025.129267","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Authors. Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"129267"}}