{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,4]],"date-time":"2026-07-04T18:19:46Z","timestamp":1783189186906,"version":"3.54.6"},"reference-count":40,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100013254","name":"National College Students Innovation and Entrepreneurship Training Program","doi-asserted-by":"publisher","award":["S202510472036"],"award-info":[{"award-number":["S202510472036"]}],"id":[{"id":"10.13039\/501100013254","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100006407","name":"Henan Province Natural Science Foundation","doi-asserted-by":"publisher","award":["252300423175"],"award-info":[{"award-number":["252300423175"]}],"id":[{"id":"10.13039\/501100006407","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Talanta"],"published-print":{"date-parts":[[2026,9]]},"DOI":"10.1016\/j.talanta.2026.129891","type":"journal-article","created":{"date-parts":[[2026,4,27]],"date-time":"2026-04-27T06:30:46Z","timestamp":1777271446000},"page":"129891","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"special_numbering":"C","title":["A polydopamine nanoparticles-blended carboxymethylcellulose hydrogel for integrated postoperative management of breast cancer: Preventing recurrence\/metastasis and promoting wound healing"],"prefix":"10.1016","volume":"307","author":[{"given":"Yongli","family":"Shi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuxin","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Saifei","family":"Lv","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-4938-019X","authenticated-orcid":false,"given":"Xianting","family":"Zeng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-0529-4755","authenticated-orcid":false,"given":"Mengting","family":"Yan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chenxu","family":"Lv","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lu","family":"Ren","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yingyu","family":"Su","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tong","family":"Ren","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yanan","family":"Lu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xueyan","family":"Hou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.talanta.2026.129891_bib1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.jconrel.2019.12.005","article-title":"Exosome-mediated siRNA delivery to suppress postoperative breast cancer metastasis","volume":"318","author":"Zhao","year":"2020","journal-title":"J. Contr. Release"},{"key":"10.1016\/j.talanta.2026.129891_bib2","doi-asserted-by":"crossref","DOI":"10.1016\/j.phymed.2024.155427","article-title":"Uncovering the effect and mechanism of Jiawei Xiaoyao Wan in treating breast cancer complicated with depression based on network pharmacology and experimental analysis","volume":"128","author":"Bai","year":"2024","journal-title":"Phytomedicine"},{"key":"10.1016\/j.talanta.2026.129891_bib3","doi-asserted-by":"crossref","first-page":"1694","DOI":"10.1016\/j.cell.2022.03.033","article-title":"Quiescent cancer cells resist T cell attack by forming an immunosuppressive niche","volume":"185","author":"Baldominos","year":"2022","journal-title":"Cell"},{"key":"10.1016\/j.talanta.2026.129891_bib4","doi-asserted-by":"crossref","first-page":"1517","DOI":"10.1016\/S1470-2045(22)00613-1","article-title":"Eliminating breast surgery for invasive breast cancer in exceptional responders to neoadjuvant systemic therapy: a multicentre, single-arm, phase 2 trial","volume":"21","author":"Kuerer","year":"2022","journal-title":"Lancet Oncol."},{"key":"10.1016\/j.talanta.2026.129891_bib5","doi-asserted-by":"crossref","first-page":"1341","DOI":"10.1080\/14740338.2022.2151584","article-title":"Chemotherapy in patients with early breast cancer: clinical overview and management of long-term side effects","volume":"21","author":"Di Nardo","year":"2022","journal-title":"Expert Opin. Drug Saf."},{"key":"10.1016\/j.talanta.2026.129891_bib6","doi-asserted-by":"crossref","first-page":"4554","DOI":"10.1111\/jocn.17479","article-title":"Symptom clusters in breast cancer patients receiving adjuvant chemotherapy: a systematic review","volume":"33","author":"Qi","year":"2024","journal-title":"J. Clin. Nurs."},{"key":"10.1016\/j.talanta.2026.129891_bib7","doi-asserted-by":"crossref","DOI":"10.1016\/j.carbpol.2024.121931","article-title":"Oxidized cellulose-filled double thermo\/pH-sensitive hydrogel for local chemo-photothermal therapy in breast cancer","volume":"332","author":"Zhang","year":"2024","journal-title":"Carbohydr. Polym."},{"key":"10.1016\/j.talanta.2026.129891_bib8","doi-asserted-by":"crossref","DOI":"10.1016\/j.ijbiomac.2023.126358","article-title":"Photothermal hyaluronic acid composite hydrogel targeting cancer stem cells for inhibiting recurrence and metastasis of breast cancer","volume":"252","author":"Wang","year":"2023","journal-title":"Int. J. Biol. Macromol."},{"key":"10.1016\/j.talanta.2026.129891_bib9","doi-asserted-by":"crossref","DOI":"10.1016\/j.carbpol.2024.122569","article-title":"Self-enhanced PTX@HSA-HA loaded functionalized injectable hydrogel for effective local chemo-photothermal therapy in breast cancer","volume":"345","author":"Gao","year":"2024","journal-title":"Carbohydr. Polym."},{"key":"10.1016\/j.talanta.2026.129891_bib10","article-title":"Copper peroxide\/manganese dioxide nanoparticles crosslinked hyaluronan hydrogel for enhanced chemodynamic\/photodynamic\/photothermal therapy in breast cancer","volume":"703","author":"Wang","year":"2025","journal-title":"J. Colloid Interface Sci."},{"key":"10.1016\/j.talanta.2026.129891_bib11","doi-asserted-by":"crossref","DOI":"10.1016\/j.ijbiomac.2024.138930","article-title":"Chitosan-based thermosensitive injectable hydrogel with hemostatic and antibacterial activity for preventing breast cancer postoperative recurrence and metastasis via chemo-photothermal therapy","volume":"290","author":"Hou","year":"2025","journal-title":"Int. J. Biol. Macromol."},{"key":"10.1016\/j.talanta.2026.129891_bib12","doi-asserted-by":"crossref","DOI":"10.3389\/fphar.2025.1681276","article-title":"A thermo-sensitive peptide hydrogel loaded with paclitaxel and antimony nanosheets for synergistic photothermal-chemotherapeutic treatment of breast cancer","volume":"16","author":"Yan","year":"2025","journal-title":"Front. Pharmacol."},{"key":"10.1016\/j.talanta.2026.129891_bib13","doi-asserted-by":"crossref","first-page":"11291","DOI":"10.1021\/acs.nanolett.5c02344","article-title":"Fe-chelated polydopamine nanoparticles prepared through photo-fenton reaction for combined photothermal\/chemodynamic antibacterial therapy","volume":"25","author":"Gao","year":"2025","journal-title":"Nano Lett."},{"key":"10.1016\/j.talanta.2026.129891_bib14","doi-asserted-by":"crossref","DOI":"10.1016\/j.jcis.2025.137332","article-title":"Calcium peroxide functionalized mesoporous polydopamine nanoparticles triggered calcium overload for synergistic tumor gas\/photothermal therapy","volume":"690","author":"Liu","year":"2025","journal-title":"J. Colloid Interface Sci."},{"key":"10.1016\/j.talanta.2026.129891_bib15","article-title":"A simple nanoplatform of thermo-sensitive liposomes and gold nanorods to treat bone metastasis through improved chemotherapy combined with photothermal therapy","volume":"X 8","author":"Gu","year":"2024","journal-title":"Int. J. Pharm."},{"key":"10.1016\/j.talanta.2026.129891_bib16","doi-asserted-by":"crossref","first-page":"2390","DOI":"10.1021\/acs.molpharmaceut.2c00164","article-title":"Sequential dual delivery system based on siCOX-2-loaded gold nanostar and thermal-sensitive liposomes overcome hypoxia-mediated multidrug resistance in tumors","volume":"19","author":"Huang","year":"2022","journal-title":"Mol. Pharm."},{"key":"10.1016\/j.talanta.2026.129891_bib17","doi-asserted-by":"crossref","first-page":"2232","DOI":"10.1016\/j.xphs.2024.03.007","article-title":"Combined photothermal therapy and cancer immunotherapy by immunogenic hollow mesoporous silicon-shelled gold nanorods","volume":"113","author":"Cao","year":"2024","journal-title":"J. Pharm. Sci."},{"key":"10.1016\/j.talanta.2026.129891_bib18","doi-asserted-by":"crossref","DOI":"10.1002\/advs.202409155","article-title":"Black phosphorus nanosheets-loaded mussel-inspired hydrogel with wet adhesion, photothermal antimicrobial, and in situ remineralization capabilities for caries prevention","volume":"11","author":"Ran","year":"2024","journal-title":"Adv. Sci."},{"key":"10.1016\/j.talanta.2026.129891_bib19","doi-asserted-by":"crossref","DOI":"10.1016\/j.jcis.2025.138422","article-title":"RC48-targeted two-dimensional black phosphorus nanoplatform for precise photothermal-immunotherapy of HER2-positive breast cancer","volume":"700","author":"Xiao","year":"2025","journal-title":"J. Colloid Interface Sci."},{"key":"10.1016\/j.talanta.2026.129891_bib20","doi-asserted-by":"crossref","first-page":"257","DOI":"10.3390\/pharmaceutics15010257","article-title":"pH-responsive hydrogel as a potential oral delivery system of baicalin for prolonging gastroprotective activity","volume":"15","author":"Xu","year":"2023","journal-title":"Pharmaceutics"},{"key":"10.1016\/j.talanta.2026.129891_bib21","doi-asserted-by":"crossref","first-page":"1131","DOI":"10.2147\/IJN.S400798","article-title":"Sustained-release esketamine based nanoparticle-hydrogel delivery system for neuropathic pain management","volume":"18","author":"Zhang","year":"2023","journal-title":"Int. J. Nanomed."},{"key":"10.1016\/j.talanta.2026.129891_bib22","doi-asserted-by":"crossref","first-page":"747","DOI":"10.1016\/j.jconrel.2024.05.021","article-title":"Microenvironment responsive hydrogel exerting inhibition of cascade immune activation and elimination of synovial fibroblasts for rheumatoid arthritis therapy","volume":"370","author":"Wu","year":"2024","journal-title":"J. Contr. Release"},{"key":"10.1016\/j.talanta.2026.129891_bib23","doi-asserted-by":"crossref","first-page":"770","DOI":"10.1007\/s13346-022-01236-0","article-title":"Pirfenidone-loaded hyaluronic acid methacryloyl hydrogel for preventing epidural adhesions after laminectomy","volume":"13","author":"Ji","year":"2023","journal-title":"Drug Deliv. Transl. Res."},{"key":"10.1016\/j.talanta.2026.129891_bib24","doi-asserted-by":"crossref","first-page":"2356","DOI":"10.1021\/acsabm.4c01846","article-title":"Polyacrylamide-based hydrogel with biocompatibility and tunable stiffness for three-dimensional cell culture","volume":"8","author":"Wang","year":"2025","journal-title":"ACS Appl. Bio Mater."},{"key":"10.1016\/j.talanta.2026.129891_bib25","doi-asserted-by":"crossref","DOI":"10.1002\/bip.70032","article-title":"Green agarose hydrogel implants with high biocompatibility for skin repair and regeneration in photoaged skin","volume":"116","author":"Guo","year":"2025","journal-title":"Biopolymers"},{"key":"10.1016\/j.talanta.2026.129891_bib26","doi-asserted-by":"crossref","first-page":"2105","DOI":"10.1021\/acs.molpharmaceut.2c01062","article-title":"Polyaspartic acid-stabilized CaCO3-containing in situ hydrogel for protection and treatment of gastric ulcer","volume":"20","author":"Xu","year":"2023","journal-title":"Mol. Pharm."},{"key":"10.1016\/j.talanta.2026.129891_bib27","doi-asserted-by":"crossref","first-page":"61679","DOI":"10.1021\/acsami.4c13489","article-title":"Rapid hemostasis tumor in situ hydrogel vaccines for colorectal cancer chemo-immunotherapy","volume":"16","author":"Qiu","year":"2024","journal-title":"ACS Appl. Mater. Interfaces"},{"key":"10.1016\/j.talanta.2026.129891_bib28","article-title":"Photo-crosslinking injectable photothermal antibacterial hydrogel based on quaternary ammonium grafted chitosan and hyaluronic acid for infected wound healing","volume":"29","author":"Ma","year":"2024","journal-title":"Mater. Today Bio"},{"key":"10.1016\/j.talanta.2026.129891_bib29","doi-asserted-by":"crossref","DOI":"10.1016\/j.ijbiomac.2024.137819","article-title":"Microenvironment-responsive Bletilla polysaccharide hydrogel with photothermal antibacterial and macrophage polarization-regulating properties for diabetic wound healing","volume":"283","author":"Hu","year":"2024","journal-title":"Int. J. Biol. Macromol."},{"key":"10.1016\/j.talanta.2026.129891_bib30","doi-asserted-by":"crossref","first-page":"3262","DOI":"10.1021\/acsbiomaterials.5c00597","article-title":"Hydrogel-based strategies for managing rheumatoid arthritis: from sustained drug release to cell-based therapies","volume":"11","author":"Back","year":"2025","journal-title":"ACS Biomater. Sci. Eng."},{"key":"10.1016\/j.talanta.2026.129891_bib31","doi-asserted-by":"crossref","first-page":"19286","DOI":"10.1021\/acsami.4c20390","article-title":"Facile nanocomposite hydrogel scaffold with sustained drug release and osteo-immunomodulatory effects to enhance bone regeneration","volume":"17","author":"Zhao","year":"2025","journal-title":"ACS Appl. Mater. Interfaces"},{"key":"10.1016\/j.talanta.2026.129891_bib33","article-title":"Enhanced anti-tumor efficacy of berberine-loaded mesoporous polydopamine nanoparticles for synergistic chemotherapy and photothermal therapy","volume":"252","author":"Wang","year":"2023","journal-title":"Int. J. Biol. Macromol."},{"key":"10.1016\/j.talanta.2026.129891_bib34","article-title":"Multifunctional injectable hydrogel incorporated with CuS nanoparticles for concurrent photothermal-chemotherapy, breast cancer recurrence prevention and wound healing","volume":"294","author":"Shi","year":"2025","journal-title":"Int. J. Biol. Macromol."},{"key":"10.1016\/j.talanta.2026.129891_bib35","doi-asserted-by":"crossref","first-page":"42674","DOI":"10.1021\/acsami.5c07288","article-title":"Photothermal hyaluronic acid composite hydrogel targeting cancer stem cells for inhibiting recurrence and metastasis of breast cancer","volume":"17","author":"Hou","year":"2025","journal-title":"ACS Appl. Mater. Interfaces"},{"key":"10.1016\/j.talanta.2026.129891_bib36","article-title":"A sodium alginate-based injectable hydrogel system for locoregional treatment of colorectal cancer by eliciting pyroptosis and apoptosis","volume":"247","author":"Shi","year":"2025","journal-title":"Colloids Surf., B"},{"key":"10.1016\/j.talanta.2026.129891_bib37","doi-asserted-by":"crossref","first-page":"619","DOI":"10.1007\/s00604-025-07481-7","article-title":"Injectable doxorubicin-loaded hyaluronic acid-based hydrogel for locoregional therapy and inhibiting metastasis of breast cancer","volume":"192","author":"Yang","year":"2025","journal-title":"Mikrochim. Acta"},{"key":"10.1016\/j.talanta.2026.129891_bib38","doi-asserted-by":"crossref","first-page":"2940","DOI":"10.1021\/acsami.4c16333","article-title":"Synthesis of near-infrared molybdenum oxide nanoparticle-functionalized metal-organic frameworks and their application in antitumor studies","volume":"17","author":"Zhao","year":"2025","journal-title":"ACS Appl. Mater. Interfaces"},{"key":"10.1016\/j.talanta.2026.129891_bib39","article-title":"Self-healing oxidized dextran\/sodium alginate hydrogel dressing with hemostatic activity speeds up wound healing in burn injuries","volume":"321","author":"Su","year":"2025","journal-title":"Int. J. Biol. Macromol."},{"key":"10.1016\/j.talanta.2026.129891_bib40","doi-asserted-by":"crossref","DOI":"10.1016\/j.ijbiomac.2024.139125","article-title":"Injectable dual-network hyaluronic acid nanocomposite hydrogel for prevention of postoperative breast cancer recurrence and wound healing","volume":"291","author":"Zhang","year":"2025","journal-title":"Int. J. Biol. Macromol."},{"key":"10.1016\/j.talanta.2026.129891_bib41","series-title":"Immunosensors","first-page":"238","author":"Kumar","year":"2019"}],"container-title":["Talanta"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0039914026005473?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0039914026005473?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,7,4]],"date-time":"2026-07-04T17:47:19Z","timestamp":1783187239000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0039914026005473"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9]]},"references-count":40,"alternative-id":["S0039914026005473"],"URL":"https:\/\/doi.org\/10.1016\/j.talanta.2026.129891","relation":{},"ISSN":["0039-9140"],"issn-type":[{"value":"0039-9140","type":"print"}],"subject":[],"published":{"date-parts":[[2026,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"A polydopamine nanoparticles-blended carboxymethylcellulose hydrogel for integrated postoperative management of breast cancer: Preventing recurrence\/metastasis and promoting wound healing","name":"articletitle","label":"Article Title"},{"value":"Talanta","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.talanta.2026.129891","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"129891"}}