{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,31]],"date-time":"2026-10-31T06:31:11Z","timestamp":1793428271608,"version":"4.5.0"},"reference-count":55,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2027,3,1]],"date-time":"2027-03-01T00:00:00Z","timestamp":1803859200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2027,3,1]],"date-time":"2027-03-01T00:00:00Z","timestamp":1803859200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2027,3,1]],"date-time":"2027-03-01T00:00:00Z","timestamp":1803859200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2027,3,1]],"date-time":"2027-03-01T00:00:00Z","timestamp":1803859200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2027,3,1]],"date-time":"2027-03-01T00:00:00Z","timestamp":1803859200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2027,3,1]],"date-time":"2027-03-01T00:00:00Z","timestamp":1803859200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2027,3,1]],"date-time":"2027-03-01T00:00:00Z","timestamp":1803859200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100002763","name":"Bu Ali Sina University","doi-asserted-by":"publisher","award":["12153"],"award-info":[{"award-number":["12153"]}],"id":[{"id":"10.13039\/501100002763","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100009694","name":"Bu-Ali Sina University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100009694","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012155","name":"National Institute for Medical Research Development","doi-asserted-by":"publisher","award":["4041546"],"award-info":[{"award-number":["4041546"]}],"id":[{"id":"10.13039\/501100012155","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Talanta"],"published-print":{"date-parts":[[2027,3]]},"DOI":"10.1016\/j.talanta.2026.130760","type":"journal-article","created":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T06:38:28Z","timestamp":1791527908000},"page":"130760","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"PA","title":["On-chip liquid phase microextraction integrated with a COF-modified electrochemical sensor for trace determination of morphine in urine"],"prefix":"10.1016","volume":"313","author":[{"given":"Maryam","family":"Mehrban","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6876-7633","authenticated-orcid":false,"given":"Tayyebeh","family":"Madrakian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3559-2080","authenticated-orcid":false,"given":"Abbas","family":"Afkhami","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9467-8522","authenticated-orcid":false,"given":"Amir Mahdi","family":"Tavassoli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hossein","family":"Khalilian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammad Ali","family":"Zolfigol","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"9\u201310","key":"10.1016\/j.talanta.2026.130760_bib1","doi-asserted-by":"crossref","first-page":"1890","DOI":"10.1002\/jssc.202000045","article-title":"High\u2010throughput microscale extraction using ionic liquids and derivatives: a review","volume":"43","author":"Trujillo\u2010Rodr\u00edguez","year":"2020","journal-title":"J. Sep. Sci."},{"issue":"3","key":"10.1016\/j.talanta.2026.130760_bib2","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1007\/s00604-012-0773-x","article-title":"Developments in hollow fiber based liquid-phase microextraction: principles and applications","volume":"177","author":"Ghambarian","year":"2012","journal-title":"Microchim. Acta"},{"key":"10.1016\/j.talanta.2026.130760_bib3","doi-asserted-by":"crossref","DOI":"10.1016\/j.chroma.2023.463825","article-title":"Solid supports and supported liquid membranes for different liquid phase microextraction and electromembrane extraction configurations. A review","volume":"1691","author":"Oca\u00f1a-Gonz\u00e1lez","year":"2023","journal-title":"J. Chromatogr. A"},{"key":"10.1016\/j.talanta.2026.130760_bib4","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/j.chroma.2018.04.051","article-title":"A comprehensive study of a new versatile microchip device based liquid phase microextraction for stopped-flow and double-flow conditions","volume":"1556","author":"Pay\u00e1n","year":"2018","journal-title":"J. Chromatogr. A"},{"key":"10.1016\/j.talanta.2026.130760_bib5","doi-asserted-by":"crossref","DOI":"10.1016\/j.microc.2025.116074","article-title":"Next-generation green preconcentration with gel-based electromembrane extraction","author":"Khan","year":"2025","journal-title":"Microchem. J."},{"key":"10.1016\/j.talanta.2026.130760_bib6","doi-asserted-by":"crossref","DOI":"10.1016\/j.trac.2022.116749","article-title":"Interfacing liquid-phase microextraction with electrochemical detection: a critical review","volume":"157","author":"Sahragard","year":"2022","journal-title":"TrAC, Trends Anal. Chem."},{"key":"10.1016\/j.talanta.2026.130760_bib7","article-title":"Emerging trends in miniaturized and microfluidic electrochemical sensing platforms","volume":"33","author":"Mohan","year":"2022","journal-title":"Curr. Opin. Electrochem."},{"issue":"10","key":"10.1016\/j.talanta.2026.130760_bib8","doi-asserted-by":"crossref","first-page":"517","DOI":"10.3390\/chemosensors11100517","article-title":"Electrochemical sensors for liquid biopsy and their integration into lab-on-chip platforms: revolutionizing the approach to diseases","volume":"11","author":"Umme","year":"2023","journal-title":"Chemosensors"},{"key":"10.1016\/j.talanta.2026.130760_bib9","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1016\/j.trac.2018.03.013","article-title":"Combined extraction and microextraction techniques: recent trends and future perspectives","volume":"103","author":"Sajid","year":"2018","journal-title":"TrAC, Trends Anal. Chem."},{"issue":"12","key":"10.1016\/j.talanta.2026.130760_bib10","doi-asserted-by":"crossref","first-page":"3920","DOI":"10.1039\/D0CS00049C","article-title":"Two-dimensional covalent organic frameworks with hierarchical porosity","volume":"49","author":"Liang","year":"2020","journal-title":"Chem. Soc. Rev."},{"key":"10.1016\/j.talanta.2026.130760_bib11","doi-asserted-by":"crossref","DOI":"10.1021\/acs.chemrev.4c00950","article-title":"Semiconducting covalent organic frameworks","author":"Jiang","year":"2025","journal-title":"Chem. Rev."},{"issue":"12","key":"10.1016\/j.talanta.2026.130760_bib12","doi-asserted-by":"crossref","first-page":"6871","DOI":"10.1039\/D0CS01569E","article-title":"Covalent organic frameworks (COFs) for electrochemical applications","volume":"50","author":"Zhao","year":"2021","journal-title":"Chem. Soc. Rev."},{"issue":"1","key":"10.1016\/j.talanta.2026.130760_bib13","doi-asserted-by":"crossref","first-page":"33","DOI":"10.17816\/RA624003","article-title":"History and prospects for the use of morphine in clinical practice: literature review","volume":"18","author":"Raspopin","year":"2024","journal-title":"Reg. Anesth. Acute Pain Manag."},{"issue":"1","key":"10.1016\/j.talanta.2026.130760_bib14","doi-asserted-by":"crossref","first-page":"29","DOI":"10.31002\/ijose.v7i1.207","article-title":"Gas chromatography mass spectroscopy (GCMS) qualitative analysis for morphine, heroin and Codeine used in doping","volume":"7","author":"Haerussana","year":"2023","journal-title":"Indones. J. Sci. Educ."},{"issue":"8","key":"10.1016\/j.talanta.2026.130760_bib15","doi-asserted-by":"crossref","first-page":"420","DOI":"10.3390\/toxics10080420","article-title":"Detection of morphine and opioids in fingernails: immunohistochemical analysis and confirmation with ultra-high-performance liquid chromatography coupled with high-resolution mass spectrometry","volume":"10","author":"Scendoni","year":"2022","journal-title":"Toxics"},{"key":"10.1016\/j.talanta.2026.130760_bib16","doi-asserted-by":"crossref","DOI":"10.1016\/j.talo.2021.100041","article-title":"Field amplified sample stacking and in-capillary derivatization for forensic analysis of morphine and morphine-6-glucuronide in human urine by capillary electrophoresis","volume":"3","author":"Zarad","year":"2021","journal-title":"Talanta Open"},{"issue":"23","key":"10.1016\/j.talanta.2026.130760_bib17","doi-asserted-by":"crossref","first-page":"3038","DOI":"10.1039\/D0AY00648C","article-title":"Detection of morphine in urine based on a surface plasmon resonance imaging immunoassay","volume":"12","author":"Ke","year":"2020","journal-title":"Anal. Methods"},{"issue":"3","key":"10.1016\/j.talanta.2026.130760_bib18","doi-asserted-by":"crossref","first-page":"508","DOI":"10.1016\/j.jpba.2008.06.022","article-title":"Chemiluminescence detection of opium poppy (Papaver somniferum) alkaloids","volume":"48","author":"Francis","year":"2008","journal-title":"J. Pharm. Biomed. Anal."},{"key":"10.1016\/j.talanta.2026.130760_bib19","series-title":"Journal of Physics: Conference Series","article-title":"Detection and identification of morphine in blood of male white rats (rattus norvegicus) by ultraviolet-visible spectrophotometry","author":"Alfian","year":"2018"},{"issue":"3","key":"10.1016\/j.talanta.2026.130760_bib20","doi-asserted-by":"crossref","first-page":"1907","DOI":"10.4067\/S0717-97072013000300025","article-title":"Kinetic spectrophotometry method for the determination of morphine, Nalbuphine and Naltrexone drugs in bulk and pharmaceutical formulations","volume":"58","author":"El-Didamony","year":"2013","journal-title":"J. Chil. Chem. Soc."},{"issue":"1","key":"10.1016\/j.talanta.2026.130760_bib21","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-025-97220-y","article-title":"Rank annihilation factor analysis for kinetic spectrophotometric determination of morphine in unknown samples","volume":"15","author":"Bahram","year":"2025","journal-title":"Sci. Rep."},{"issue":"7","key":"10.1016\/j.talanta.2026.130760_bib22","doi-asserted-by":"crossref","first-page":"2299","DOI":"10.1021\/acs.chemmater.7b05121","article-title":"Mechanistic insight into hydrogen-bond-controlled crystallinity and adsorption property of covalent organic frameworks from flexible building blocks","volume":"30","author":"Guo","year":"2018","journal-title":"Chem. Mater."},{"key":"10.1016\/j.talanta.2026.130760_bib23","doi-asserted-by":"crossref","DOI":"10.1016\/j.foodchem.2024.141606","article-title":"Synthesis of a triazine based COF and its application for the establishment of an electrochemical sensor for the simultaneous determination of Cd2+ and Pb2+ in edible specimens using Box-Behnken design","volume":"464","author":"Sarvestani","year":"2025","journal-title":"Food Chem."},{"key":"10.1016\/j.talanta.2026.130760_bib24","doi-asserted-by":"crossref","DOI":"10.1016\/j.microc.2024.110627","article-title":"Synthesis, characterization, and electrochemical application of novel poly (Cu2P4BCl4) based glassy carbon electrodes for determination of sulfamethoxazole in pharmaceutical serum and urine samples and Cow's milk","volume":"201","author":"Metto","year":"2024","journal-title":"Microchem. J."},{"issue":"5751","key":"10.1016\/j.talanta.2026.130760_bib25","doi-asserted-by":"crossref","first-page":"1166","DOI":"10.1126\/science.1120411","article-title":"Porous, crystalline, covalent organic frameworks","volume":"310","author":"C\u00f4t\u00e9","year":"2005","journal-title":"Science"},{"issue":"48","key":"10.1016\/j.talanta.2026.130760_bib26","doi-asserted-by":"crossref","first-page":"19524","DOI":"10.1021\/ja308278w","article-title":"Construction of crystalline 2D covalent organic frameworks with remarkable chemical (acid\/base) stability via a combined reversible and irreversible route","volume":"134","author":"Kandambeth","year":"2012","journal-title":"J. Am. Chem. Soc."},{"issue":"5","key":"10.1016\/j.talanta.2026.130760_bib27","doi-asserted-by":"crossref","first-page":"711","DOI":"10.1351\/pac199163050711","article-title":"Real surface area measurements in electrochemistry","volume":"63","author":"Trasatti","year":"1991","journal-title":"Pure Appl"},{"issue":"37","key":"10.1016\/j.talanta.2026.130760_bib28","doi-asserted-by":"crossref","first-page":"8699","DOI":"10.1021\/acs.jpclett.2c02464","article-title":"Voltammetry of carbon nanotubes and the limitations of particle-modified electrodes: are carbon nanotubes electrocatalytic?","volume":"13","author":"Kaliyaraj Selva Kumar","year":"2022","journal-title":"J. Phys. Chem. Lett."},{"key":"10.1016\/j.talanta.2026.130760_bib29","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1016\/j.carbon.2020.09.003","article-title":"Redox active covalent organic framework-based conductive nanofibers for flexible energy storage device","volume":"171","author":"Kong","year":"2021","journal-title":"Carbon"},{"issue":"1","key":"10.1016\/j.talanta.2026.130760_bib30","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-023-38643-3","article-title":"Fabrication of impedimetric sensor based on metallic nanoparticle for the determination of mesna anticancer drug","volume":"13","author":"Mehrban","year":"2023","journal-title":"Sci. Rep."},{"issue":"20","key":"10.1016\/j.talanta.2026.130760_bib31","doi-asserted-by":"crossref","first-page":"14194","DOI":"10.1039\/D4RA01356E","article-title":"Electrochemical sensing performance of two CuO nanomaterial-modified dual-working electrodes","volume":"14","author":"Chang","year":"2024","journal-title":"RSC Adv."},{"key":"10.1016\/j.talanta.2026.130760_bib32","doi-asserted-by":"crossref","DOI":"10.3389\/fchem.2020.601044","article-title":"Electrochemical sensors based on covalent organic frameworks: a critical review","volume":"8","author":"Chen","year":"2020","journal-title":"Front. Chem."},{"issue":"6","key":"10.1016\/j.talanta.2026.130760_bib33","doi-asserted-by":"crossref","first-page":"1408","DOI":"10.1016\/j.bios.2009.10.037","article-title":"Electrochemical determination of morphine at ordered mesoporous carbon modified glassy carbon electrode","volume":"25","author":"Li","year":"2010","journal-title":"Biosens. Bioelectron."},{"issue":"17","key":"10.1016\/j.talanta.2026.130760_bib34","doi-asserted-by":"crossref","first-page":"1419","DOI":"10.1002\/elan.200302966","article-title":"Voltammetric oxidation of drugs of abuse I. Morphine and metabolites","volume":"16","author":"Garrido","year":"2004","journal-title":"Electroanalysis: An International Journal Devoted to Fundamental and Practical Aspects of Electroanalysis"},{"key":"10.1016\/j.talanta.2026.130760_bib35","doi-asserted-by":"crossref","DOI":"10.1016\/j.envint.2023.107928","article-title":"Covalent organic frameworks (COFs) and metal\u2013organic frameworks (MOFs) as electrochemical sensors for the efficient detection of pharmaceutical residues","volume":"175","author":"Mohan","year":"2023","journal-title":"Environ. Int."},{"issue":"3","key":"10.1016\/j.talanta.2026.130760_bib36","doi-asserted-by":"crossref","first-page":"378","DOI":"10.1093\/chromsci\/bmw188","article-title":"Efficiency of hollow fiber liquid-phase microextraction chromatography methods in the separation of organic compounds: a review","volume":"55","author":"Alsharif","year":"2017","journal-title":"J. Chromatogr. Sci."},{"key":"10.1016\/j.talanta.2026.130760_bib37","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1016\/j.aca.2015.09.052","article-title":"A new effective on chip electromembrane extraction coupled with high performance liquid chromatography for enhancement of extraction efficiency","volume":"898","author":"Asl","year":"2015","journal-title":"Anal. Chim. Acta"},{"issue":"8","key":"10.1016\/j.talanta.2026.130760_bib38","doi-asserted-by":"crossref","first-page":"7102","DOI":"10.1039\/C6NJ00505E","article-title":"Sensitive and simple simultaneous determination of morphine and codeine using a Zn 2 SnO 4 nanoparticle\/graphene composite modified electrochemical sensor","volume":"40","author":"Bagheri","year":"2016","journal-title":"New J. Chem."},{"issue":"1\u20132","key":"10.1016\/j.talanta.2026.130760_bib39","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1016\/j.ejps.2011.11.007","article-title":"Lipophilicity of morphine microspecies and their contribution to the lipophilicity profile","volume":"45","author":"Maz\u00e1k","year":"2012","journal-title":"Eur. J. Pharmaceut. Sci."},{"issue":"7","key":"10.1016\/j.talanta.2026.130760_bib40","doi-asserted-by":"crossref","first-page":"647","DOI":"10.1021\/jm00241a001","article-title":"Microelectrometric titration measurement of the pka's and partition and drug distribution coefficients of narcotics and narcotic antagonists and their pH and temperature dependence","volume":"18","author":"Kaufman","year":"1975","journal-title":"J. Med. Chem."},{"issue":"1\u20132","key":"10.1016\/j.talanta.2026.130760_bib41","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.chroma.2005.07.110","article-title":"Surfactant enhanced liquid-phase microextraction of basic drugs of abuse in hair combined with high performance liquid chromatography","volume":"1094","author":"Yazdi","year":"2005","journal-title":"J. Chromatogr. A"},{"issue":"9","key":"10.1016\/j.talanta.2026.130760_bib42","doi-asserted-by":"crossref","first-page":"4581","DOI":"10.3168\/jds.2009-2267","article-title":"Designing and analyzing quantitative factorial experiments","volume":"92","author":"St-Pierre","year":"2009","journal-title":"J. Dairy Sci."},{"key":"10.1016\/j.talanta.2026.130760_bib43","series-title":"Experimental Design and Analysis","author":"Seltman","year":"2012"},{"key":"10.1016\/j.talanta.2026.130760_bib44","series-title":"Design and Analysis of Experiments","author":"Montgomery","year":"2017"},{"issue":"460","key":"10.1016\/j.talanta.2026.130760_bib45","first-page":"1216","article-title":"Response surface methodology: process and product optimization using designed experiments","volume":"97","author":"Anderson-Cook","year":"2002","journal-title":"J. Am. Stat. Assoc."},{"key":"10.1016\/j.talanta.2026.130760_bib46","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1016\/j.aca.2019.05.075","article-title":"Liquid-Phase microextraction and electromembrane extraction in millifluidic devices: a tutorial","volume":"1080","author":"Ramos-Pay\u00e1n","year":"2019","journal-title":"Anal. Chim. Acta"},{"key":"10.1016\/j.talanta.2026.130760_bib47","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1016\/j.aca.2012.05.023","article-title":"Liquid-phase microextraction in a microfluidic-chip\u2013high enrichment and sample clean-up from small sample volumes based on three-phase extraction","volume":"735","author":"Pay\u00e1n","year":"2012","journal-title":"Anal. Chim. Acta"},{"key":"10.1016\/j.talanta.2026.130760_bib48","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1016\/j.electacta.2013.04.064","article-title":"Gold nanoparticles modified carbon paste electrode as an efficient electrochemical sensor for rapid and sensitive determination of cefixime in urine and pharmaceutical samples","volume":"103","author":"Afkhami","year":"2013","journal-title":"Electrochim. Acta"},{"issue":"3","key":"10.1016\/j.talanta.2026.130760_bib49","doi-asserted-by":"crossref","first-page":"845","DOI":"10.1016\/j.talanta.2009.05.011","article-title":"Simple and rapid voltammetric determination of morphine at electrochemically pretreated glassy carbon electrodes","volume":"79","author":"Li","year":"2009","journal-title":"Talanta"},{"key":"10.1016\/j.talanta.2026.130760_bib50","series-title":"Eurachem Guide: the Fitness for Purpose of Analytical Methods \u2013 a Laboratory Guide to Method Validation and Related Topics","author":"Cantwell","year":"2025"},{"key":"10.1016\/j.talanta.2026.130760_bib51","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1016\/j.bios.2013.10.035","article-title":"A new platform for sensing urinary morphine based on carrier assisted electromembrane extraction followed by adsorptive stripping voltammetric detection on screen-printed electrode","volume":"54","author":"Ahmar","year":"2014","journal-title":"Biosens. Bioelectron."},{"issue":"1","key":"10.1016\/j.talanta.2026.130760_bib52","doi-asserted-by":"crossref","first-page":"8099","DOI":"10.1038\/s41598-024-58843-9","article-title":"Machine learning-enhanced drug testing for simultaneous morphine and methadone detection in urinary biofluids","volume":"14","author":"Habibi","year":"2024","journal-title":"Sci. Rep."},{"issue":"1","key":"10.1016\/j.talanta.2026.130760_bib53","article-title":"Electrochemical measurement of morphine using a sensor fabricated from the CuS\/g-C3N5\/Ag nanocomposite","volume":"14","author":"Teymourinia","year":"2024","journal-title":"Sci. Rep."},{"key":"10.1016\/j.talanta.2026.130760_bib54","doi-asserted-by":"crossref","DOI":"10.1016\/j.chemosphere.2023.138451","article-title":"Optimization and analytical behavior of a morphine electrochemical sensor in environmental and biological samples based on graphite rod electrode using graphene\/Co3O4 nanocomposite","volume":"326","author":"Wang","year":"2023","journal-title":"Chemosphere"},{"key":"10.1016\/j.talanta.2026.130760_bib55","doi-asserted-by":"crossref","DOI":"10.1016\/j.electacta.2021.137803","article-title":"Highly sensitive electrochemical sensor based on Pt nanoparticles\/carbon nanohorns for simultaneous determination of morphine and MDMA in biological samples","volume":"370","author":"Zhang","year":"2021","journal-title":"Electrochim. Acta"}],"container-title":["Talanta"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0039914026014165?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0039914026014165?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,10,31]],"date-time":"2026-10-31T05:38:07Z","timestamp":1793425087000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0039914026014165"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2027,3]]},"references-count":55,"alternative-id":["S0039914026014165"],"URL":"https:\/\/doi.org\/10.1016\/j.talanta.2026.130760","relation":{},"ISSN":["0039-9140"],"issn-type":[{"value":"0039-9140","type":"print"}],"subject":[],"published":{"date-parts":[[2027,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"On-chip liquid phase microextraction integrated with a COF-modified electrochemical sensor for trace determination of morphine in urine","name":"articletitle","label":"Article Title"},{"value":"Talanta","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.talanta.2026.130760","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"130760"}}