{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,14]],"date-time":"2026-02-14T10:44:06Z","timestamp":1771065846225,"version":"3.50.1"},"reference-count":32,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2020,3,1]],"date-time":"2020-03-01T00:00:00Z","timestamp":1583020800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,3,1]],"date-time":"2020-03-01T00:00:00Z","timestamp":1583020800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Topics in Companion Animal Medicine"],"published-print":{"date-parts":[[2020,3]]},"DOI":"10.1016\/j.tcam.2020.100406","type":"journal-article","created":{"date-parts":[[2020,1,23]],"date-time":"2020-01-23T19:35:44Z","timestamp":1579808144000},"page":"100406","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":5,"special_numbering":"C","title":["Hematological and Hemostatic Alterations Associated With a Single Extracorporeal Renal Replacement Therapy in Dogs With Acute Kidney Injury Associated Leptospirosis: A Pilot Study"],"prefix":"10.1016","volume":"38","author":[{"given":"Anthony","family":"Barth\u00e9lemy","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amandine","family":"Viol\u00e9","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maxime","family":"Cambournac","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Benoit","family":"Rannou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jeanne-Marie","family":"Bonnet-Garin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jean-Yves","family":"Ayoub","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emmanuel","family":"Boselli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C\u00e9line","family":"Pouzot-Nevoret","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Isabelle","family":"Goy-Thollot","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.tcam.2020.100406_bib0001","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1136\/vr.c6234","article-title":"Prognosis of acute kidney injury in dogs using RIFLE (Risk, Injury, Failure, Loss and End-stage renal failure)-like criteria","volume":"168","author":"Lee","year":"2011","journal-title":"Vet Rec"},{"key":"10.1016\/j.tcam.2020.100406_bib0002","series-title":"Fluid therapy in small animal practice","first-page":"528","article-title":"Hemodialysis","author":"Cowgill","year":"2000"},{"key":"10.1016\/j.tcam.2020.100406_bib0003","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1111\/vec.12028","article-title":"Extracorporeal renal replacement therapy and blood purification in critical care","volume":"23","author":"Cowgill","year":"2013","journal-title":"J Vet Emerg Crit Care"},{"key":"10.1016\/j.tcam.2020.100406_bib0004","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1080\/003655100750046440","article-title":"Activation of coagulation during treatment with hemodialysis","volume":"60","author":"Bartels","year":"2000","journal-title":"Scand J Clin Lab Invest"},{"key":"10.1016\/j.tcam.2020.100406_bib0005","doi-asserted-by":"crossref","first-page":"4717","DOI":"10.1016\/S0142-9612(03)00380-6","article-title":"On the influence of flow conditions and wettability on blood material interactions","volume":"24","author":"Spijker","year":"2003","journal-title":"Biomaterials"},{"key":"10.1016\/j.tcam.2020.100406_bib0006","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1111\/j.1542-4758.2007.00166.x","article-title":"Essentials of anticoagulation in hemodialysis","volume":"11","author":"Fischer","year":"2007","journal-title":"Hemodial Int"},{"key":"10.1016\/j.tcam.2020.100406_bib0007","doi-asserted-by":"crossref","first-page":"280","DOI":"10.5301\/IJAO.2011.6469","article-title":"Prothrombotic changes in platelet, endothelial and coagulation function following hemodialysis","volume":"34","author":"Milburn","year":"2011","journal-title":"Int J Artif Organs"},{"key":"10.1016\/j.tcam.2020.100406_bib0008","doi-asserted-by":"crossref","first-page":"428","DOI":"10.1093\/ndt\/6.6.428","article-title":"Comparison of blood biocompatibility during haemodialysis with cuprophane and polyacrylonitrile membranes","volume":"6","author":"Seyfert","year":"1991","journal-title":"Nephrol Dial Transplant"},{"key":"10.1016\/j.tcam.2020.100406_bib0009","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1177\/039139889201500503","article-title":"Hemostatic disturbances induced by two hollow-fiber hemodialysis membranes","volume":"15","author":"Reber","year":"1992","journal-title":"Int J Artif Organs"},{"key":"10.1016\/j.tcam.2020.100406_bib0010","doi-asserted-by":"crossref","first-page":"871","DOI":"10.1681\/ASN.V76871","article-title":"A comparison of three brands of polysulfone membranes","volume":"7","author":"Hoenich","year":"1996","journal-title":"J Am Soc Nephrol"},{"key":"10.1016\/j.tcam.2020.100406_bib0011","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1046\/j.1525-1594.1999.06289.x","article-title":"Platelet-leukocyte aggregates during hemodialysis: effect of membrane type","volume":"23","author":"Gawaz","year":"1999","journal-title":"Artif Organs"},{"key":"10.1016\/j.tcam.2020.100406_bib0012","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1111\/j.1939-1676.1993.tb01011.x","article-title":"Hemolytic uremic syndrome in dogs","volume":"7","author":"Holloway","year":"1993","journal-title":"J Vet Intern Med"},{"key":"10.1016\/j.tcam.2020.100406_bib0013","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1111\/jvim.14626","article-title":"Hemorrhagic, hemostatic, and thromboelastometric disorders in 35 dogs with a clinical diagnosis of leptospirosis: a prospective study","volume":"31","author":"Barth\u00e9lemy","year":"2017","journal-title":"J Vet Intern Med"},{"key":"10.1016\/j.tcam.2020.100406_bib0014","series-title":"AMC dialysis handbook","first-page":"3","author":"Langston","year":"2010"},{"key":"10.1016\/j.tcam.2020.100406_bib0015","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1016\/j.cvsm.2010.09.001","article-title":"Continuous renal replacement therapy in dogs and cats","volume":"41","author":"Acierno","year":"2011","journal-title":"Vet Clin North Am Small Anim Pract"},{"key":"10.1016\/j.tcam.2020.100406_bib0016","series-title":"Small animal critical care medicine","first-page":"1058","article-title":"Renal replacement therapies","author":"Palm","year":"2015"},{"key":"10.1016\/j.tcam.2020.100406_bib0017","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1111\/jvim.14867","article-title":"Regional citrate anticoagulation for intermittent hemodialysis in dogs","volume":"32","author":"Francey","year":"2018","journal-title":"J Vet Intern Med"},{"key":"10.1016\/j.tcam.2020.100406_bib0018","doi-asserted-by":"crossref","first-page":"379","DOI":"10.7754\/Clin.Lab.2014.140931","article-title":"Assessment of hemostatic changes after initiation of continuous venovenous hemodialysis","volume":"61","author":"Wand","year":"2015","journal-title":"Clin Lab"},{"key":"10.1016\/j.tcam.2020.100406_bib0019","first-page":"1","article-title":"Changes in fibrinolytic activity during the course of a single hemodialysis session","volume":"24","author":"Kurz","year":"1985","journal-title":"Clin Nephrol"},{"key":"10.1016\/j.tcam.2020.100406_bib0020","series-title":"Small animal clinical diagnosis by laboratory methods","first-page":"14","article-title":"The complete blood count and bone marrow examination: general comments and selected techniques","author":"Weiss","year":"2004"},{"key":"10.1016\/j.tcam.2020.100406_bib0021","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/vec.12144","article-title":"Partnership on Rotational ViscoElastic Test Standardization (PROVETS): evidence-based guidelines on rotational viscoelastic assays in veterinary medicine","volume":"24","author":"Goggs","year":"2014","journal-title":"J Vet Emerg Crit Care"},{"key":"10.1016\/j.tcam.2020.100406_bib0022","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1111\/vec.12145","article-title":"Systematic evaluation of evidence on veterinary viscoelastic testing part 4: definitions and data reporting","volume":"24","author":"Hanel","year":"2014","journal-title":"J Vet Emerg Crit Care"},{"key":"10.1016\/j.tcam.2020.100406_bib0023","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1038\/ki.2012.130","article-title":"Hemodialysis effect on platelet count and function and hemodialysis-associated thrombocytopenia","volume":"82","author":"Daugirdas","year":"2012","journal-title":"Kidney Int"},{"key":"10.1016\/j.tcam.2020.100406_bib0024","doi-asserted-by":"crossref","first-page":"2864","DOI":"10.1182\/blood-2016-11-709873","article-title":"Heparin-induced thrombocytopenia","volume":"129","author":"Arepally","year":"2017","journal-title":"Blood"},{"key":"10.1016\/j.tcam.2020.100406_bib0025","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1160\/TH04-12-0825","article-title":"Clinical features of heparin-induced thrombocytopenia including risk factors for thrombosis. A retrospective analysis of 408 patients","volume":"94","author":"Greinacher","year":"2005","journal-title":"Thromb Haemost"},{"key":"10.1016\/j.tcam.2020.100406_bib0026","doi-asserted-by":"crossref","first-page":"897","DOI":"10.1172\/JCI108710","article-title":"Hemodialysis leukopenia; pulmonary vascular leukocytosis resulting from complement activation by dialyzer cellophane membrane","volume":"59","author":"Craddock","year":"1977","journal-title":"J Clin Invest"},{"key":"10.1016\/j.tcam.2020.100406_bib0027","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1046\/j.1526-0968.2002.00453.x","article-title":"Blood purification procedures and their related short and long-term effect on patient","volume":"6","author":"Nos\u00e9","year":"2002","journal-title":"Ther Apher"},{"key":"10.1016\/j.tcam.2020.100406_bib0028","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1111\/jvim.14658","article-title":"Blood Transfusions in Dogs and Cats Receiving Hemodialysis: 230 Cases (June 1997-September 2012)","volume":"31","author":"Langston","year":"2017","journal-title":"J Vet Intern Med"},{"key":"10.1016\/j.tcam.2020.100406_bib0029","doi-asserted-by":"crossref","first-page":"789","DOI":"10.2460\/ajvr.73.6.789","article-title":"Correlation of hematocrit, platelet concentration, and plasma coagulation factors with results of thromboelastometry in canine whole blood samples","volume":"73","author":"Smith","year":"2012","journal-title":"Am J Vet Res"},{"key":"10.1016\/j.tcam.2020.100406_bib0030","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1111\/jcpt.12415","article-title":"Antifactor Xa levels vs. activated partial thromboplastin time for monitoring unfractionated heparin. A pilot study","volume":"41","author":"Samuel","year":"2016","journal-title":"J Clin Pharm Ther"},{"key":"10.1016\/j.tcam.2020.100406_bib0031","doi-asserted-by":"crossref","first-page":"324","DOI":"10.1056\/NEJM197208172870703","article-title":"A prospective study of the value of monitoring heparin treatment with the activated partial thromboplastin time","volume":"7","author":"Basu","year":"1972","journal-title":"N Engl J Med"},{"key":"10.1016\/j.tcam.2020.100406_bib0032","doi-asserted-by":"crossref","first-page":"188S","DOI":"10.1378\/chest.126.3_suppl.188S","article-title":"Heparin and low-molecular-weight heparin: the Seventh ACCP Conference on Antithrombotic and Thrombolytic Therapy","volume":"126","author":"Hirsh","year":"2004","journal-title":"Chest"}],"container-title":["Topics in Companion Animal Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1938973620300040?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1938973620300040?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,30]],"date-time":"2025-10-30T18:38:02Z","timestamp":1761849482000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1938973620300040"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,3]]},"references-count":32,"alternative-id":["S1938973620300040"],"URL":"https:\/\/doi.org\/10.1016\/j.tcam.2020.100406","relation":{},"ISSN":["1938-9736"],"issn-type":[{"value":"1938-9736","type":"print"}],"subject":[],"published":{"date-parts":[[2020,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Hematological and Hemostatic Alterations Associated With a Single Extracorporeal Renal Replacement Therapy in Dogs With Acute Kidney Injury Associated Leptospirosis: A Pilot Study","name":"articletitle","label":"Article Title"},{"value":"Topics in Companion Animal Medicine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.tcam.2020.100406","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"100406"}}