{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,30]],"date-time":"2025-10-30T18:47:48Z","timestamp":1761850068115,"version":"build-2065373602"},"reference-count":21,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2021,3,1]],"date-time":"2021-03-01T00:00:00Z","timestamp":1614556800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,3,1]],"date-time":"2021-03-01T00:00:00Z","timestamp":1614556800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Topics in Companion Animal Medicine"],"published-print":{"date-parts":[[2021,3]]},"DOI":"10.1016\/j.tcam.2020.100502","type":"journal-article","created":{"date-parts":[[2020,11,26]],"date-time":"2020-11-26T12:51:33Z","timestamp":1606395093000},"page":"100502","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Presumptive Lornoxicam Intoxication in Four Dogs"],"prefix":"10.1016","volume":"42","author":[{"given":"Vicky","family":"Karakitsou","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katerina","family":"Adamama-Moraitou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lysimachos G.","family":"Papazoglou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"George","family":"Kazakos","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dimitrios","family":"Timiou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas","family":"Polydoros","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anatoli","family":"Tahmazidou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mathios E.","family":"Mylonakis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.tcam.2020.100502_bib0001","doi-asserted-by":"crossref","first-page":"969","DOI":"10.1016\/j.cvsm.2018.06.003","article-title":"Toxicology of frequently encountered nonsteroidal anti-inflammatory drugs in dogs and cats: An Update","volume":"48","author":"McLean","year":"2018","journal-title":"Vet Clin North Am Small Anim Pract"},{"key":"10.1016\/j.tcam.2020.100502_bib0002","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1111\/j.1939-1676.1989.tb00863.x","article-title":"Gastroduodenal ulceration in dogs. Retrospective study of 43 cases and literature review","volume":"3","author":"Stanton","year":"1989","journal-title":"J Vet Intern Med"},{"key":"10.1016\/j.tcam.2020.100502_bib0003","doi-asserted-by":"crossref","first-page":"1112","DOI":"10.2460\/javma.2005.227.1112","article-title":"Gastrointestinal tract perforation in dogs treated with a selective cyclooxygenase-2 inhibitor: 29 cases (2002-2003)","volume":"227","author":"Lascelles","year":"2005","journal-title":"J Am Vet Med Assoc"},{"key":"10.1016\/j.tcam.2020.100502_bib0004","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1111\/j.1476-4431.2005.00157.x","article-title":"Gastrointestinal perforation in five dogs associated with the administration of meloxicam","volume":"16","author":"Enberg","year":"2006","journal-title":"J Vet Emerg Crit Care"},{"key":"10.1016\/j.tcam.2020.100502_bib0005","doi-asserted-by":"crossref","first-page":"436","DOI":"10.1136\/vr.165.15.436","article-title":"Spontaneous gastroduodenal perforations in dogs \u2013 a retrospective study of 15 cases","volume":"165","author":"Cariou","year":"2009","journal-title":"Vet Rec"},{"key":"10.1016\/j.tcam.2020.100502_bib0006","doi-asserted-by":"crossref","first-page":"625","DOI":"10.1111\/jsap.12151","article-title":"Septic peritonitis from pyloric and non-pyloric gastrointestinal perforation: prognostic factors in 44 dogs and 11 cats","volume":"54","author":"Dayer","year":"2013","journal-title":"J Small Anim Pract"},{"key":"10.1016\/j.tcam.2020.100502_bib0007","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1111\/jsap.12631","article-title":"Clinical findings and results of diagnostic imaging in 82 dogs with gastrointestinal ulceration","volume":"58","author":"Fitzgerald","year":"2017","journal-title":"J Small Anim Pract"},{"key":"10.1016\/j.tcam.2020.100502_bib0008","doi-asserted-by":"crossref","first-page":"639","DOI":"10.2165\/00003495-199651040-00008","article-title":"Lornoxicam. A review of its pharmacology and therapeutic potential in the management of painful and inflammatory conditions","volume":"51","author":"Balfour","year":"1996","journal-title":"Drugs"},{"key":"10.1016\/j.tcam.2020.100502_bib0009","doi-asserted-by":"crossref","first-page":"445","DOI":"10.2217\/pmt.16.7","article-title":"Tolerability of the COX-1\/COX-2 inhibitor lornoxicam in the treatment of acute and reumatoid pain","volume":"6","author":"Parada","year":"2016","journal-title":"Pain Manag"},{"key":"10.1016\/j.tcam.2020.100502_bib0010","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1024\/0036-7281\/a000186","article-title":"Severe gastrointestinal bleeding secondary to lornoxicam in the dog","volume":"153","author":"Kook","year":"2011","journal-title":"Schweiz Arch Tierheilkd"},{"key":"10.1016\/j.tcam.2020.100502_bib0011","first-page":"123","article-title":"Intoxication by lornoxicam in two dogs","volume":"44","author":"Albuquerque","year":"2016","journal-title":"Acta Sci Vet"},{"key":"10.1016\/j.tcam.2020.100502_bib0012","doi-asserted-by":"crossref","first-page":"1366","DOI":"10.1023\/A:1005560104847","article-title":"Interaction between NSAIDs and steroid in rat stomach: safety of nimesulide as a preferential COX-2 inhibitor in the stomach","volume":"45","author":"Kataoka","year":"2000","journal-title":"Dig Dis Sci"},{"key":"10.1016\/j.tcam.2020.100502_bib0013","first-page":"971","article-title":"Nonsteroidal anti-inflammatory drug-induced duodenal ulceration and perforation in a mature rottweiler","volume":"43","author":"Reed","year":"2002","journal-title":"Can Vet J"},{"key":"10.1016\/j.tcam.2020.100502_bib0014","doi-asserted-by":"crossref","first-page":"176","DOI":"10.5326\/0380176","article-title":"Spontaneous gastroduodenal perforation in 16 dogs and seven cats (1982-1999)","volume":"38","author":"Hinton","year":"2002","journal-title":"J Am Anim Hosp Assoc"},{"key":"10.1016\/j.tcam.2020.100502_bib0015","first-page":"507","article-title":"Challenging diagnosis-Icterus associated with a single perforating duodenal ulcer after long-term nonsteroidal antiinflammatory drug administration in a dog","volume":"45","author":"Duerr","year":"2004","journal-title":"Can Vet J"},{"key":"10.1016\/j.tcam.2020.100502_bib0016","doi-asserted-by":"crossref","first-page":"255","DOI":"10.5326\/0460255","article-title":"Proximal duodenal perforation in three dogs following deracoxib administration","volume":"46","author":"Case","year":"2010","journal-title":"J Am Anim Hosp Assoc"},{"key":"10.1016\/j.tcam.2020.100502_bib0017","doi-asserted-by":"crossref","first-page":"1082","DOI":"10.1213\/01.ANE.0000105866.99259.94","article-title":"Acetylsalicylic acid, diclofenac, and lornoxicam, but not rofecoxib, affect platelet CD 62 expression","volume":"98","author":"Blaicher","year":"2004","journal-title":"Anesth Analg"},{"key":"10.1016\/j.tcam.2020.100502_bib0018","doi-asserted-by":"crossref","first-page":"726","DOI":"10.1017\/S0265021508004274","article-title":"Preemptive analgesia by lornoxicam -an NSAID- significantly inhibits perioperative platelet aggregation","volume":"25","author":"Felfernig","year":"2008","journal-title":"Eur J Anaesthesiol"},{"key":"10.1016\/j.tcam.2020.100502_bib0019","doi-asserted-by":"crossref","first-page":"1823","DOI":"10.1111\/jvim.15337","article-title":"ACVIM consensus statement: Support for rational administration of gastrointestinal protectants to dogs and cats","volume":"32","author":"Marks","year":"2018","journal-title":"J Vet Intern Med"},{"key":"10.1016\/j.tcam.2020.100502_bib0020","doi-asserted-by":"crossref","first-page":"87","DOI":"10.5326\/15473317-37-1-87","article-title":"Surgical Treatment of septic peritonitis without abdominal drainage in 28 dogs","volume":"37","author":"Lantz","year":"2001","journal-title":"J Am Anim Hosp Assoc"},{"key":"10.1016\/j.tcam.2020.100502_bib0021","doi-asserted-by":"crossref","first-page":"1203","DOI":"10.1016\/j.cvsm.2020.07.001","article-title":"Small Animal Transfusion Medicine","volume":"50","author":"Kuo","year":"2000","journal-title":"Vet Clin Small Anim"}],"container-title":["Topics in Companion Animal Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1938973620301008?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1938973620301008?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,30]],"date-time":"2025-10-30T18:39:16Z","timestamp":1761849556000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1938973620301008"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,3]]},"references-count":21,"alternative-id":["S1938973620301008"],"URL":"https:\/\/doi.org\/10.1016\/j.tcam.2020.100502","relation":{},"ISSN":["1938-9736"],"issn-type":[{"type":"print","value":"1938-9736"}],"subject":[],"published":{"date-parts":[[2021,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Presumptive Lornoxicam Intoxication in Four Dogs","name":"articletitle","label":"Article Title"},{"value":"Topics in Companion Animal Medicine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.tcam.2020.100502","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"100502"}}