{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T00:54:10Z","timestamp":1790729650775,"version":"4.1.0"},"reference-count":83,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T00:00:00Z","timestamp":1693526400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T00:00:00Z","timestamp":1693526400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T00:00:00Z","timestamp":1693526400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T00:00:00Z","timestamp":1693526400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T00:00:00Z","timestamp":1693526400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T00:00:00Z","timestamp":1693526400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T00:00:00Z","timestamp":1693526400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Topics in Companion Animal Medicine"],"published-print":{"date-parts":[[2023,9]]},"DOI":"10.1016\/j.tcam.2023.100818","type":"journal-article","created":{"date-parts":[[2023,9,9]],"date-time":"2023-09-09T01:29:15Z","timestamp":1694222955000},"page":"100818","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"special_numbering":"C","title":["Clinical Assessment of Primary Hemostasis: A Review"],"prefix":"10.1016","volume":"56-57","author":[{"ORCID":"https:\/\/orcid.org\/0009-0009-7434-9583","authenticated-orcid":false,"given":"Satoshi","family":"Haginoya","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elizabeth J.","family":"Thomovsky","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paula A.","family":"Johnson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aimee C.","family":"Brooks","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.tcam.2023.100818_bib0001","doi-asserted-by":"crossref","first-page":"647","DOI":"10.1136\/vr.164.21.647","article-title":"Retrospective study of 871 dogs with thrombocytopenia","volume":"164","author":"Botsch","year":"2009","journal-title":"Vet Rec"},{"key":"10.1016\/j.tcam.2023.100818_bib0002","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1111\/jsap.12814","article-title":"Prevalence and disease associations in feline thrombocytopenia: a retrospective study of 194 cases","volume":"59","author":"Ellis","year":"2018","journal-title":"J Small Anim Pract"},{"key":"10.1016\/j.tcam.2023.100818_bib0003","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1177\/104063871002200109","article-title":"Prevalence of von Willebrand disease in dogs from Sao Paulo State, Brazil","volume":"22","author":"Mattoso","year":"2010","journal-title":"J Vet Diagn Invest"},{"key":"10.1016\/j.tcam.2023.100818_bib0004","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1084\/jem.11.4.541","article-title":"Blood-platelet AND megalokaryocyte reactions in the rabbit","volume":"11","author":"Bunting","year":"1909","journal-title":"J Exp Med"},{"key":"10.1016\/j.tcam.2023.100818_bib0005","doi-asserted-by":"crossref","first-page":"278","DOI":"10.1084\/jem.18.3.278","article-title":"The histogenesis of blood platelets","volume":"18","author":"Brown","year":"1913","journal-title":"J Exp Med"},{"key":"10.1016\/j.tcam.2023.100818_bib0006","doi-asserted-by":"crossref","first-page":"729","DOI":"10.1111\/j.1365-2141.1993.tb03216.x","article-title":"Biotinylated platelets: a new approach to the measurement of platelet life span","volume":"85","author":"Heilmann","year":"1993","journal-title":"Br J Haematol"},{"key":"10.1016\/j.tcam.2023.100818_bib0007","first-page":"36","article-title":"Kinetics, distribution, and sites of destruction of canine blood platelets with In-111 oxine","volume":"21","author":"L\u00f6tter","year":"1980","journal-title":"J Nucl Med"},{"key":"10.1016\/j.tcam.2023.100818_bib0008","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1002\/cyto.990070109","article-title":"Flow cytometric and radioisotopic determinations of platelet survival time in normal cats and feline leukemia virus-infected cats","volume":"7","author":"Jacobs","year":"1986","journal-title":"Cytometry"},{"key":"10.1016\/j.tcam.2023.100818_bib0009","doi-asserted-by":"crossref","first-page":"446","DOI":"10.1111\/j.1939-1676.2002.tb01263.x","article-title":"Changes in platelet life span in dogs with mitral valve regurgitation","volume":"16","author":"Tanaka","year":"2002","journal-title":"J Vet Intern Med"},{"key":"10.1016\/j.tcam.2023.100818_bib0010","first-page":"518","article-title":"Quantitation of platelet life span in splenectomized dogs","volume":"24","author":"Dale","year":"1996","journal-title":"Exp Hematol"},{"key":"10.1016\/j.tcam.2023.100818_bib0011","first-page":"565","article-title":"Cellular localization of thrombopoietin mRNA in the liver by in situ hybridization","volume":"25","author":"Nomura","year":"1997","journal-title":"Exp Hematol"},{"key":"10.1016\/j.tcam.2023.100818_bib0012","doi-asserted-by":"crossref","first-page":"3339","DOI":"10.1172\/JCI26674","article-title":"The molecular mechanisms that control thrombopoiesis","volume":"115","author":"Kaushansky","year":"2005","journal-title":"J Clin Invest"},{"key":"10.1016\/j.tcam.2023.100818_bib0013","doi-asserted-by":"crossref","first-page":"298","DOI":"10.1016\/j.jcpa.2013.03.005","article-title":"Expression of the thrombopoietin gene in tissues from healthy dogs","volume":"149","author":"Figueiredo","year":"2013","journal-title":"J Comp Pathol"},{"key":"10.1016\/j.tcam.2023.100818_bib0014","first-page":"478","article-title":"The physiological response of thrombopoietin (c-Mpl ligand) to thrombocytopenia in the rat","volume":"105","author":"Yang","year":"1999","journal-title":"Br J Haematol"},{"key":"10.1016\/j.tcam.2023.100818_bib0015","doi-asserted-by":"crossref","first-page":"567","DOI":"10.1182\/blood.V87.2.567.bloodjournal872567","article-title":"Thrombopoietin in thrombocytopenic mice: evidence against regulation at the mRNA level and for a direct regulatory role of platelets","volume":"87","author":"Stoffel","year":"1996","journal-title":"Blood"},{"key":"10.1016\/j.tcam.2023.100818_bib0016","series-title":"Platelets","first-page":"47","article-title":"The structure of resting and activated platelets","author":"Thomas","year":"2019"},{"key":"10.1016\/j.tcam.2023.100818_bib0017","doi-asserted-by":"crossref","first-page":"5087","DOI":"10.1182\/blood-2006-12-027698","article-title":"The growing complexity of platelet aggregation","volume":"109","author":"Jackson","year":"2007","journal-title":"Blood"},{"key":"10.1016\/j.tcam.2023.100818_bib0018","series-title":"Platelets","first-page":"349","article-title":"Platelet Secretion","author":"Flaumenhaft","year":"2019"},{"key":"10.1016\/j.tcam.2023.100818_bib0019","doi-asserted-by":"crossref","first-page":"2096","DOI":"10.1182\/blood-2003-08-2804","article-title":"Characterization of the proteins released from activated platelets leads to localization of novel platelet proteins in human atherosclerotic lesions","volume":"103","author":"Coppinger","year":"2004","journal-title":"Blood"},{"key":"10.1016\/j.tcam.2023.100818_bib0020","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1172\/JCI112542","article-title":"A platelet alpha granule membrane protein that is associated with the plasma membrane after activation. Characterization and subcellular localization of platelet activation-dependent granule-external membrane protein","volume":"78","author":"Berman","year":"1986","journal-title":"J Clin Invest"},{"key":"10.1016\/j.tcam.2023.100818_bib0021","doi-asserted-by":"crossref","first-page":"306","DOI":"10.1111\/j.1939-165X.2009.00141.x","article-title":"Evaluation of platelet function screening tests to detect platelet procoagulant deficiency in dogs with Scott syndrome","volume":"38","author":"Brooks","year":"2009","journal-title":"Vet Clin Pathol"},{"key":"10.1016\/j.tcam.2023.100818_bib0022","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1111\/jvim.12325","article-title":"Platelet activation in cats with hypertrophic cardiomyopathy","volume":"28","author":"Tablin","year":"2014","journal-title":"J Vet Intern Med"},{"key":"10.1016\/j.tcam.2023.100818_bib0023","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3389\/fvets.2022.892377","article-title":"Platelet priming and activation in naturally occurring thermal burn injuries and wildfire smoke exposure is associated with intracardiac thrombosis and spontaneous echocardiographic contrast in feline survivors","volume":"9","author":"Tan","year":"2022","journal-title":"Front Vet Science"},{"key":"10.1016\/j.tcam.2023.100818_bib0024","first-page":"608","article-title":"Platelet Aggregation","author":"Hayward","year":"2019","journal-title":"Platelets"},{"key":"10.1016\/j.tcam.2023.100818_bib0025","doi-asserted-by":"crossref","first-page":"1757","DOI":"10.1152\/ajplegacy.1975.228.6.1757","article-title":"Factors responsible for ADP-induced release reaction of human platelets","volume":"228","author":"Mustard","year":"1975","journal-title":"Am J Physiol"},{"issue":"Suppl 1","key":"10.1016\/j.tcam.2023.100818_bib0026","doi-asserted-by":"crossref","first-page":"S306","DOI":"10.1016\/j.jvc.2015.10.004","article-title":"Secondary prevention of cardiogenic arterial thromboembolism in the cat: The double-blind, randomized, positive-controlled feline arterial thromboembolism; clopidogrel vs. aspirin trial (FAT CAT)","volume":"17","author":"Hogan","year":"2015","journal-title":"J Vet Cardiol"},{"key":"10.1016\/j.tcam.2023.100818_bib0027","doi-asserted-by":"crossref","first-page":"1185","DOI":"10.1161\/CIRCRESAHA.114.301597","article-title":"Platelet lipidomics: modern day perspective on lipid discovery and characterization in platelets","volume":"114","author":"O'Donnell","year":"2014","journal-title":"Circ Res"},{"key":"10.1016\/j.tcam.2023.100818_bib0028","doi-asserted-by":"crossref","first-page":"2434","DOI":"10.1182\/blood.V99.7.2434","article-title":"A hereditary bleeding disorder of dogs caused by a lack of platelet procoagulant activity","volume":"99","author":"Brooks","year":"2002","journal-title":"Blood"},{"key":"10.1016\/j.tcam.2023.100818_bib0029","doi-asserted-by":"crossref","first-page":"1402","DOI":"10.1111\/j.1939-1676.2012.01012.x","article-title":"Clinical characterization of canine platelet procoagulant deficiency (Scott syndrome)","volume":"26","author":"Jandrey","year":"2012","journal-title":"J Vet Intern Med"},{"key":"10.1016\/j.tcam.2023.100818_bib0030","doi-asserted-by":"crossref","first-page":"2240","DOI":"10.1111\/jth.13157","article-title":"A TMEM16F point mutation causes an absence of canine platelet TMEM16F and ineffective activation and death-induced phospholipid scrambling","volume":"13","author":"Brooks","year":"2015","journal-title":"J Thromb Haemost"},{"key":"10.1016\/j.tcam.2023.100818_bib0031","series-title":"Platelets","first-page":"193","article-title":"The glycoprotein Ib-IX-V complex","author":"Li","year":"2019"},{"key":"10.1016\/j.tcam.2023.100818_bib0032","doi-asserted-by":"crossref","first-page":"3354","DOI":"10.1182\/blood-2013-12-543074","article-title":"GpIb\u03b1-VWF blockade restores vessel patency by dissolving platelet aggregates formed under very high shear rate in mice","volume":"123","author":"Le Behot","year":"2014","journal-title":"Blood"},{"key":"10.1016\/j.tcam.2023.100818_bib0033","doi-asserted-by":"crossref","first-page":"1330","DOI":"10.1126\/science.1170905","article-title":"Mechanoenzymatic cleavage of the ultralarge vascular protein, von Willebrand Factor","volume":"324","author":"Zhang","year":"2009","journal-title":"Science"},{"key":"10.1016\/j.tcam.2023.100818_bib0034","doi-asserted-by":"crossref","first-page":"3322","DOI":"10.1182\/blood.V96.10.3322","article-title":"Platelets adhere to and translocate on von Willebrand factor presented by endothelium in stimulated veins","volume":"96","author":"Andr\u00e9","year":"2000","journal-title":"Blood"},{"key":"10.1016\/j.tcam.2023.100818_bib0035","series-title":"Platelets","first-page":"371","article-title":"Hemostatic thrombus formation in flowing blood","author":"Brass","year":"2019"},{"key":"10.1016\/j.tcam.2023.100818_bib0036","series-title":"Textbook of veterinary internal medicine","first-page":"2120","article-title":"Immune-Mediated Thrombocytopenia, von Willebrand Disease, and Other Platelet Disorders","author":"Callan","year":"2016"},{"key":"10.1016\/j.tcam.2023.100818_bib0037","doi-asserted-by":"crossref","first-page":"607","DOI":"10.1046\/j.1365-2516.2002.00672.x","article-title":"Italian Association of Hemophilia Centers (AICE), Guidelines for the diagnosis and management of von Willebrand disease in Italy","volume":"8","author":"Federici","year":"2002","journal-title":"Haemophilia"},{"key":"10.1016\/j.tcam.2023.100818_bib0038","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1093\/jhered\/90.1.112","article-title":"A review of canine inherited bleeding disorders: biochemical and molecular strategies for disease characterization and carrier detection","volume":"90","author":"Brooks","year":"1999","journal-title":"J Hered"},{"key":"10.1016\/j.tcam.2023.100818_bib0039","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1016\/S0195-5616(88)50017-7","article-title":"Canine von Willebrand's disease. A heterogeneous group of bleeding disorders","volume":"18","author":"Johnson","year":"1988","journal-title":"Vet Clin North Am Small Anim Pract"},{"key":"10.1016\/j.tcam.2023.100818_bib0040","doi-asserted-by":"crossref","first-page":"926","DOI":"10.2460\/javma.1996.209.05.926","article-title":"Severe, recessive von Willebrand's disease in German Wirehaired Pointers","volume":"209","author":"Brooks","year":"1996","journal-title":"J Am Vet Med Assoc"},{"key":"10.1016\/j.tcam.2023.100818_bib0041","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1354\/vp.41-3-221","article-title":"A von Willebrand's factor genomic nucleotide variant and polymerase chain reaction diagnostic test associated with inheritable type-2 von Willebrand's disease in a line of German shorthaired pointer dogs","volume":"41","author":"Kramer","year":"2004","journal-title":"Vet Pathol"},{"key":"10.1016\/j.tcam.2023.100818_bib0042","doi-asserted-by":"crossref","first-page":"1123","DOI":"10.2460\/javma.1992.200.08.1123","article-title":"Epidemiologic features of von Willebrand's disease in Doberman pinschers, Scottish terriers, and Shetland sheepdogs: 260 cases (1984-1988)","volume":"200","author":"Brooks","year":"1992","journal-title":"J Am Vet Med Assoc"},{"key":"10.1016\/j.tcam.2023.100818_bib0043","doi-asserted-by":"crossref","first-page":"1342","DOI":"10.2460\/javma.1990.197.10.1342","article-title":"Clinical and laboratory features of a severe form of von Willebrand disease in Shetland sheepdogs","volume":"197","author":"Raymond","year":"1990","journal-title":"J Am Vet Med Assoc"},{"key":"10.1016\/j.tcam.2023.100818_bib0044","doi-asserted-by":"crossref","first-page":"1261","DOI":"10.2460\/javma.1980.176.11.1261","article-title":"A bleeding disease (von Willebrand's disease) in a Chesapeake Bay Retriever","volume":"176","author":"Johnson","year":"1980","journal-title":"J Am Vet Med Assoc"},{"key":"10.1016\/j.tcam.2023.100818_bib0045","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1080\/01652176.1998.9694847","article-title":"Type III von Willebrand's disease in Dutch kooiker dogs","volume":"20","author":"Slappendel","year":"1998","journal-title":"Vet Q"},{"key":"10.1016\/j.tcam.2023.100818_bib0046","unstructured":"eClinpath, Platelet number, https:\/\/eclinpath.com\/hemostasis\/disorders\/platelet-numbers\/, 2022 (Accessed September 13, 2022)."},{"key":"10.1016\/j.tcam.2023.100818_bib0047","series-title":"Small Animal Critical Care Medicine","first-page":"554","article-title":"Bleeding disorders","author":"Hackner","year":"2015"},{"key":"10.1016\/j.tcam.2023.100818_bib0048","first-page":"696","article-title":"Studies of platelet-bound and serum platelet-bindable immunoglobulins in dogs with idiopathic thrombocytopenic purpura","volume":"24","author":"Lewis","year":"1996","journal-title":"Exp Hematol"},{"issue":"Suppl 1","key":"10.1016\/j.tcam.2023.100818_bib0049","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1111\/vcp.12774","article-title":"Immune thrombocytopenia (ITP): pathophysiology update and diagnostic dilemmas","volume":"48","author":"LeVine","year":"2019","journal-title":"Vet Clin Pathol"},{"key":"10.1016\/j.tcam.2023.100818_bib0050","doi-asserted-by":"crossref","first-page":"1691","DOI":"10.1111\/jvim.14831","article-title":"Thrombocytosis in 715 Dogs (2011-2015)","volume":"31","author":"Woolcock","year":"2017","journal-title":"J Vet Intern Med"},{"key":"10.1016\/j.tcam.2023.100818_bib0051","doi-asserted-by":"crossref","first-page":"587","DOI":"10.2460\/javma.1979.175.06.587","article-title":"Ocular manifestations of the Ch\u00e9diak-Higashi syndrome in four species of animals","volume":"175","author":"Collier","year":"1979","journal-title":"J Am Vet Med Assoc"},{"key":"10.1016\/j.tcam.2023.100818_bib0052","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1186\/s12881-019-0922-8","article-title":"Identification of a compound heterozygote in LYST gene: a case report on Chediak-Higashi syndrome","volume":"21","author":"Song","year":"2020","journal-title":"BMC Med Genet"},{"key":"10.1016\/j.tcam.2023.100818_bib0053","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1038\/s41598-019-56896-9","article-title":"Assisted reproduction mediated resurrection of a feline model for Chediak-Higashi syndrome caused by a large duplication in LYST","volume":"10","author":"Buckley","year":"2020","journal-title":"Sci Rep"},{"key":"10.1016\/j.tcam.2023.100818_bib0054","series-title":"Platelets","first-page":"877","article-title":"Inherited disorders of platelet function","author":"Cattaneo","year":"2019"},{"key":"10.1016\/j.tcam.2023.100818_bib0055","series-title":"Textbook of Veterinary Internal Medicine","first-page":"2137","article-title":"Immune-mediated and other nonneoplastic white blood cell disorders","author":"Johns","year":"2016"},{"key":"10.1016\/j.tcam.2023.100818_bib0056","first-page":"107","article-title":"Hemostasis","author":"Boudreaux","year":"2011","journal-title":"Duncan & Prasse's Veterinary Laboratory Medicine Clinical Pathology"},{"key":"10.1016\/j.tcam.2023.100818_bib0057","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1111\/j.1939-165X.1988.tb00477.x","article-title":"Estimating platelets and leukocytes on canine blood smears","volume":"17","author":"Tvedten","year":"1988","journal-title":"Vet Clin Pathol"},{"key":"10.1016\/j.tcam.2023.100818_bib0058","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1111\/j.1939-165X.1999.tb01041.x","article-title":"Estimation of platelet counts on feline blood smears","volume":"28","author":"S\u00e9verine","year":"1999","journal-title":"Vet Clin Pathol"},{"key":"10.1016\/j.tcam.2023.100818_bib0059","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1111\/j.1939-165X.1988.tb00479.x","article-title":"Oral mucosa bleeding times of normal cats and cats with Chediak-Higashi syndrome or Hageman Trait (Factor XII Deficiency)","volume":"17","author":"Parker","year":"1988","journal-title":"Vet Clin Pathol"},{"key":"10.1016\/j.tcam.2023.100818_bib0060","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1177\/1098612X13502973","article-title":"Reference values and repeatability of buccal mucosal bleeding time in healthy sedated cats","volume":"16","author":"Alatzas","year":"2014","journal-title":"J Feline Med Surg"},{"key":"10.1016\/j.tcam.2023.100818_bib0061","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1111\/vcp.12087","article-title":"Comparison of the buccal mucosal bleeding time in dogs using 3 different-sized lancet devices","volume":"42","author":"Aumann","year":"2013","journal-title":"Vet Clin Pathol"},{"key":"10.1016\/j.tcam.2023.100818_bib0062","doi-asserted-by":"crossref","first-page":"777","DOI":"10.1055\/s-0038-1649669","article-title":"Buccal mucosa bleeding time is prolonged in canine models of primary hemostatic disorders","volume":"70","author":"Brooks","year":"1993","journal-title":"Thromb Haemost"},{"key":"10.1016\/j.tcam.2023.100818_bib0063","doi-asserted-by":"crossref","first-page":"1337","DOI":"10.2460\/ajvr.1987.48.09.1337","article-title":"Buccal mucosa bleeding times of healthy dogs and of dogs in various pathologic states, including thrombocytopenia, uremia, and von Willebrand's disease","volume":"48","author":"Jergens","year":"1987","journal-title":"Am J Vet Res"},{"key":"10.1016\/j.tcam.2023.100818_bib0064","first-page":"344","article-title":"Evaluating oral mucosa bleeding times in healthy dogs using a spring-loaded device","volume":"30","author":"Forsythe","year":"1989","journal-title":"Can Vet J"},{"key":"10.1016\/j.tcam.2023.100818_bib0065","first-page":"48","article-title":"Experimentally induced renal failure in the dog as an animal model of uremic bleeding","volume":"124","author":"Brassard","year":"1994","journal-title":"J Lab Clin Med"},{"key":"10.1016\/j.tcam.2023.100818_bib0066","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1053\/rvsc.1999.0334","article-title":"An interobserver and intraobserver study of buccal mucosal bleeding time in Greyhounds","volume":"68","author":"Sato","year":"2000","journal-title":"Res Vet Sci"},{"key":"10.1016\/j.tcam.2023.100818_bib0067","doi-asserted-by":"crossref","first-page":"652","DOI":"10.2460\/ajvr.2001.62.652","article-title":"Assessment of a point-of-care instrument for identification of primary hemostatic disorders in dogs","volume":"62","author":"Callan","year":"2001","journal-title":"Am J Vet Res"},{"key":"10.1016\/j.tcam.2023.100818_bib0068","first-page":"252","article-title":"Evaluation of laboratory methods to improve characterization of dogs with von Willebrand disease","volume":"73","author":"Burgess","year":"2009","journal-title":"Can J Vet Res"},{"key":"10.1016\/j.tcam.2023.100818_bib0069","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1111\/j.1939-165X.2008.00062.x","article-title":"Platelet function in clinically healthy cats and cats with hypertrophic cardiomyopathy: analysis using the Platelet Function Analyzer-100","volume":"37","author":"Jandrey","year":"2008","journal-title":"Vet Clin Pathol"},{"key":"10.1016\/j.tcam.2023.100818_bib0070","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1016\/j.rvsc.2016.09.011","article-title":"Influence of a low dosage of clopidogrel on platelet function in cats as measured by the platelet function analyser PFA-100 and the multiplate analyser","volume":"109","author":"Teuber","year":"2016","journal-title":"Res Vet Sci"},{"key":"10.1016\/j.tcam.2023.100818_bib0071","doi-asserted-by":"crossref","first-page":"961","DOI":"10.1046\/j.1365-2141.2002.03511.x","article-title":"Assessment of thrombocytopenic disorders using the Platelet Function Analyzer (PFA-100\u00ae)*","volume":"117","author":"Carcao","year":"2002","journal-title":"Br J Haematol"},{"key":"10.1016\/j.tcam.2023.100818_bib0072","doi-asserted-by":"crossref","first-page":"20","DOI":"10.3109\/09537104.2010.514967","article-title":"The new INNOVANCE\u00ae PFA P2Y cartridge is sensitive to the detection of the P2Y\u2081\u2082 receptor inhibition","volume":"22","author":"Koessler","year":"2011","journal-title":"Platelets"},{"key":"10.1016\/j.tcam.2023.100818_bib0073","doi-asserted-by":"crossref","first-page":"491","DOI":"10.1080\/09537100701280654","article-title":"Clopidogrel anti-platelet effect: an evaluation by optical aggregometry, impedance aggregometry, and the platelet function analyzer (PFA-100)","volume":"18","author":"Dyszkiewicz-Korpanty","year":"2007","journal-title":"Platelets"},{"key":"10.1016\/j.tcam.2023.100818_bib0074","doi-asserted-by":"crossref","first-page":"638","DOI":"10.1177\/1098612X16648182","article-title":"Assessment of platelet function in healthy cats in response to commonly prescribed antiplatelet drugs using three point-of-care platelet function tests","volume":"19","author":"Ho","year":"2017","journal-title":"J Feline Med Surg"},{"key":"10.1016\/j.tcam.2023.100818_bib0075","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1111\/jvim.14886","article-title":"Comparison of multiplate, platelet function analyzer-200, and plateletworks in healthy dogs treated with aspirin and clopidogrel","volume":"32","author":"Saati","year":"2018","journal-title":"J Vet Intern Med"},{"key":"10.1016\/j.tcam.2023.100818_bib0076","series-title":"Platelets","first-page":"593","article-title":"Clinical Tests of Platelet Function","author":"Lordkipanidze","year":"2019"},{"key":"10.1016\/j.tcam.2023.100818_bib0077","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1055\/s-0029-1220325","article-title":"Whole blood platelet aggregometry and platelet function testing","volume":"35","author":"McGlasson","year":"2009","journal-title":"Semin Thromb Hemost"},{"key":"10.1016\/j.tcam.2023.100818_bib0078","doi-asserted-by":"crossref","first-page":"871","DOI":"10.1016\/0049-3848(87)90098-3","article-title":"Epinephrine does not induce platelet aggregation in citrated whole blood","volume":"45","author":"Joseph","year":"1987","journal-title":"Thrombosis Res"},{"key":"10.1016\/j.tcam.2023.100818_bib0079","doi-asserted-by":"crossref","first-page":"509","DOI":"10.3389\/fped.2019.00509","article-title":"TEG platelet mapping and impedance aggregometry to predict platelet transfusion during cardiopulmonary bypass in pediatric patients","volume":"7","author":"Barker","year":"2019","journal-title":"Front Pediatr"},{"key":"10.1016\/j.tcam.2023.100818_bib0080","doi-asserted-by":"crossref","first-page":"189","DOI":"10.3390\/jcm9010189","article-title":"Sensitivity of viscoelastic tests to platelet function","volume":"9","author":"Ranucci","year":"2020","journal-title":"J Clin Med"},{"key":"10.1016\/j.tcam.2023.100818_bib0081","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1111\/j.1939-165X.2012.00419.x","article-title":"Evaluation of thrombelastographic platelet-mapping in healthy cats","volume":"41","author":"Blois","year":"2012","journal-title":"Vet Clin Pathol"},{"key":"10.1016\/j.tcam.2023.100818_bib0082","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1186\/1477-9560-5-3","article-title":"Evaluation of the TEG platelet mapping assay in blood donors","volume":"5","author":"Bochsen","year":"2007","journal-title":"Thromb J"},{"key":"10.1016\/j.tcam.2023.100818_bib0083","doi-asserted-by":"crossref","DOI":"10.1016\/j.tvjl.2022.105882","article-title":"Effectiveness of aspirin vs. clopidogrel in dogs with immune mediated haemolytic anaemia evaluated by serial thromboelastography and platelet mapping","volume":"287","author":"Griebsch","year":"2022","journal-title":"Vet J"}],"container-title":["Topics in Companion Animal Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1938973623000582?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1938973623000582?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,30]],"date-time":"2025-10-30T18:39:45Z","timestamp":1761849585000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1938973623000582"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,9]]},"references-count":83,"alternative-id":["S1938973623000582"],"URL":"https:\/\/doi.org\/10.1016\/j.tcam.2023.100818","relation":{},"ISSN":["1938-9736"],"issn-type":[{"value":"1938-9736","type":"print"}],"subject":[],"published":{"date-parts":[[2023,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Clinical Assessment of Primary Hemostasis: A Review","name":"articletitle","label":"Article Title"},{"value":"Topics in Companion Animal Medicine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.tcam.2023.100818","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"100818"}}