{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T04:30:32Z","timestamp":1791261032948,"version":"4.1.0"},"reference-count":45,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Trends in Cardiovascular Medicine"],"published-print":{"date-parts":[[2026,8]]},"DOI":"10.1016\/j.tcm.2026.08.011","type":"journal-article","created":{"date-parts":[[2026,8,22]],"date-time":"2026-08-22T22:43:53Z","timestamp":1787438633000},"update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"title":["Immediate versus staged complete revascularization in patients presenting with acute myocardial infarction and multivessel coronary artery disease: A meta-analysis with time-to-event analysis"],"prefix":"10.1016","author":[{"given":"Abdelrahman","family":"Hafez","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahmed","family":"Abdelaziz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Muhammad","family":"Desouky","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahmed","family":"Nazmy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahmed","family":"Sobhy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammed Tarek","family":"Hasan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahmed","family":"Elshahat","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahmed","family":"Mansour","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammed Sabri","family":"Hassanin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahmed Wahdan","family":"Kasem","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohamed Abdelfatah Abdallah","family":"Abdellatif","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hanaa","family":"Elsayed","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karim","family":"Atta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elena Ivanovna","family":"Gorshenina","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vasily Ivanovich","family":"Davydkin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carl J","family":"Lavie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"11","key":"10.1016\/j.tcm.2026.08.011_bib0001","doi-asserted-by":"crossref","first-page":"e1014","DOI":"10.4244\/EIJ-D-19-00034","article-title":"Multivessel percutaneous coronary intervention in patients with acute myocardial infarction and severe renal dysfunction","volume":"15","author":"Song","year":"2019","journal-title":"EuroIntervention"},{"issue":"14","key":"10.1016\/j.tcm.2026.08.011_bib0002","doi-asserted-by":"crossref","first-page":"1709","DOI":"10.1093\/eurheartj\/ehm184","article-title":"Impact of multivessel disease on reperfusion success and clinical outcomes in patients undergoing primary percutaneous coronary intervention for acute myocardial infarction","volume":"28","author":"Sorajja","year":"2007","journal-title":"Eur Heart J"},{"issue":"13","key":"10.1016\/j.tcm.2026.08.011_bib0003","first-page":"e771","article-title":"2025 ACC\/AHA\/ACEP\/NAEMSP\/SCAI guideline for the management of patients with acute coronary syndromes: a report of the american college of cardiology\/american heart association joint committee on clinical practice guidelines","volume":"151","author":"Rao","year":"2025","journal-title":"Circulation"},{"issue":"1","key":"10.1016\/j.tcm.2026.08.011_bib0004","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1093\/eurheartj\/ehi002","article-title":"Mortality rates in patients with ST-elevation vs. non-ST-elevation acute myocardial infarction: observations from an unselected cohort","volume":"26","author":"Terkelsen","year":"2005","journal-title":"Eur Heart J"},{"issue":"38","key":"10.1016\/j.tcm.2026.08.011_bib0005","doi-asserted-by":"crossref","first-page":"3720","DOI":"10.1093\/eurheartj\/ehad191","article-title":"2023 ESC guidelines for the management of acute coronary syndromes","volume":"44","author":"Byrne","year":"2023","journal-title":"Eur Heart J"},{"issue":"37","key":"10.1016\/j.tcm.2026.08.011_bib0006","doi-asserted-by":"crossref","first-page":"3579","DOI":"10.1093\/eurheartj\/ehaa481","article-title":"Management of non-culprit coronary plaques in patients with acute coronary syndrome","volume":"41","author":"Montone","year":"2020","journal-title":"Eur Heart J"},{"issue":"3","key":"10.1016\/j.tcm.2026.08.011_bib0007","doi-asserted-by":"crossref","first-page":"e171","DOI":"10.4244\/EIJ-E-23-00045","article-title":"Complete revascularisation should be immediate in STEMI: pros and cons","volume":"20","author":"Kastrati","year":"2024","journal-title":"EuroIntervention"},{"issue":"5","key":"10.1016\/j.tcm.2026.08.011_bib0008","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0303284","article-title":"In-hospital versus after-discharge complete revascularization in patients with ST segment elevation myocardial infarction and multivessel disease. REVIVA-ST trial","volume":"19","author":"Rumiz","year":"2024","journal-title":"PLoS One"},{"key":"10.1016\/j.tcm.2026.08.011_bib0009","doi-asserted-by":"crossref","DOI":"10.3389\/fcvm.2024.1475483","article-title":"Staged versus immediate complete revascularization for non-culprit arteries in acute myocardial infarction: a post-hoc analysis of FRAME-AMI","volume":"11","author":"Lim","year":"2024","journal-title":"Front Cardiovasc Med"},{"issue":"15","key":"10.1016\/j.tcm.2026.08.011_bib0010","doi-asserted-by":"crossref","first-page":"1368","DOI":"10.1056\/NEJMoa2307823","article-title":"Timing of complete revascularization with multivessel PCI for myocardial infarction","volume":"389","author":"St\u00e4hli","year":"2023","journal-title":"New England J Med"},{"issue":"18","key":"10.1016\/j.tcm.2026.08.011_bib0011","doi-asserted-by":"crossref","first-page":"1628","DOI":"10.1001\/jama.2025.16189","article-title":"Fractional flow reserve-guided complete vs culprit-only revascularization in Non-ST-Elevation myocardial infarction and multivessel disease: the SLIM randomized clinical trial","volume":"334","author":"Pustjens","year":"2025","journal-title":"JAMA"},{"key":"10.1016\/j.tcm.2026.08.011_bib0012","article-title":"The PRISMA 2020 statement: an updated guideline for reporting systematic reviews","author":"Page","year":"2021","journal-title":"BMJ"},{"key":"10.1016\/j.tcm.2026.08.011_bib0013","unstructured":"Cochrane Handbook for Systematic Reviews of Interventions | Cochrane [Internet]. [cited 2025 Dec 10]. Available from: https:\/\/www.cochrane.org\/authors\/handbooks-and-manuals\/handbook"},{"issue":"9","key":"10.1016\/j.tcm.2026.08.011_bib0014","first-page":"629","article-title":"MULTi-vessel immediate vs. STAged RevaScularization in acute myocardial infarction: the MULTISTARS AMI trial","volume":"12","author":"Rossello","year":"2023","journal-title":"Eur Heart J Acute Cardiovasc Care"},{"key":"10.1016\/j.tcm.2026.08.011_bib0015","doi-asserted-by":"crossref","DOI":"10.1136\/bmj.l4898","article-title":"RoB 2: a revised tool for assessing risk of bias in randomised trials","author":"Sterne","year":"2019","journal-title":"BMJ"},{"issue":"1","key":"10.1016\/j.tcm.2026.08.011_bib0016","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1186\/s12874-021-01308-8","article-title":"IPDfromKM: reconstruct individual patient data from published Kaplan-Meier survival curves","volume":"21","author":"Liu","year":"2021","journal-title":"BMC Med Res Methodol"},{"issue":"4","key":"10.1016\/j.tcm.2026.08.011_bib0017","doi-asserted-by":"crossref","first-page":"786","DOI":"10.1177\/1536867X1801700402","article-title":"Reconstructing time-to-event data from published Kaplan-Meier curves","volume":"17","author":"Wei","year":"2017","journal-title":"Stata J"},{"issue":"1","key":"10.1016\/j.tcm.2026.08.011_bib0018","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1186\/1471-2288-12-9","article-title":"Enhanced secondary analysis of survival data: reconstructing the data from published Kaplan-Meier survival curves","volume":"12","author":"Guyot","year":"2012","journal-title":"BMC Med Res Methodol"},{"issue":"7109","key":"10.1016\/j.tcm.2026.08.011_bib0019","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1136\/bmj.315.7109.629","article-title":"Bias in meta-analysis detected by a simple, graphical test","volume":"315","author":"Egger","year":"1997","journal-title":"BMJ"},{"issue":"1","key":"10.1016\/j.tcm.2026.08.011_bib0020","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1186\/1472-6963-4-38","article-title":"Systems for grading the quality of evidence and the strength of recommendations I: critical appraisal of existing approaches The GRADE Working Group","volume":"4","author":"Atkins","year":"2004","journal-title":"BMC Health Serv Res"},{"issue":"11","key":"10.1016\/j.tcm.2026.08.011_bib0021","doi-asserted-by":"crossref","first-page":"781","DOI":"10.5152\/AnatolJCardiol.2021.71080","volume":"25","author":"Nichita-Brendea","year":"2021","journal-title":"Anatol J Cardiol"},{"issue":"10383","key":"10.1016\/j.tcm.2026.08.011_bib0022","doi-asserted-by":"crossref","first-page":"1172","DOI":"10.1016\/S0140-6736(23)00351-3","article-title":"Immediate versus staged complete revascularisation in patients presenting with acute coronary syndrome and multivessel coronary disease (BIOVASC): a prospective, open-label, non-inferiority, randomised trial","volume":"401","author":"Diletti","year":"2023","journal-title":"The Lancet"},{"key":"10.1016\/j.tcm.2026.08.011_bib0023","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1016\/j.ahj.2023.01.020","article-title":"Immediate versus staged complete revascularization in patients with ST-segment elevation myocardial infarction and multivessel coronary artery disease: results from a prematurely discontinued randomized multicenter trial","volume":"259","author":"Park","year":"2023","journal-title":"Am Heart J"},{"issue":"22","key":"10.1016\/j.tcm.2026.08.011_bib0024","doi-asserted-by":"crossref","first-page":"2713","DOI":"10.1016\/j.jacc.2019.09.051","article-title":"Timing of staged nonculprit artery revascularization in patients With ST-segment elevation myocardial infarction: complete trial","volume":"74","author":"Wood","year":"2019","journal-title":"J Am Coll Cardiol"},{"issue":"10","key":"10.1016\/j.tcm.2026.08.011_bib0025","doi-asserted-by":"crossref","first-page":"496","DOI":"10.1016\/j.acvd.2022.05.011","article-title":"Immediate versus staged complete myocardial revascularization in patients with ST-segment elevation myocardial infarction and multivessel disease: a post hoc analysis of the randomized FLOWER-MI trial","volume":"115","author":"Tea","year":"2022","journal-title":"Arch Cardiovasc Dis"},{"issue":"7","key":"10.1016\/j.tcm.2026.08.011_bib0026","doi-asserted-by":"crossref","first-page":"704","DOI":"10.1016\/j.jacc.2011.02.071","article-title":"Prognostic impact of staged versus \u201cone-time\u201d multivessel percutaneous intervention in acute myocardial infarction: analysis from the HORIZONS-AMI (Harmonizing outcomes with revascularization and stents in acute myocardial infarction) trial","volume":"58","author":"Kornowski","year":"2011","journal-title":"J Am Coll Cardiol"},{"issue":"10507","key":"10.1016\/j.tcm.2026.08.011_bib0027","doi-asserted-by":"crossref","first-page":"1032","DOI":"10.1016\/S0140-6736(25)01529-6","article-title":"Immediate versus staged complete revascularisation during index admission in patients with ST-segment elevation myocardial infarction and multivessel disease (OPTION\u2013STEMI): a multicentre, non-inferiority, open-label, randomised trial","volume":"406","author":"Kim","year":"2025","journal-title":"Lancet"},{"issue":"9","key":"10.1016\/j.tcm.2026.08.011_bib0028","doi-asserted-by":"crossref","first-page":"662","DOI":"10.1136\/hrt.2009.177162","article-title":"A randomised trial of target-vessel versus multi-vessel revascularisation in ST-elevation myocardial infarction: major adverse cardiac events during long-term follow-up","volume":"96","author":"Politi","year":"2010","journal-title":"Heart"},{"issue":"14","key":"10.1016\/j.tcm.2026.08.011_bib0029","doi-asserted-by":"crossref","first-page":"e865","DOI":"10.4244\/EIJ-D-23-00882","article-title":"Immediate versus staged complete revascularisation in patients presenting with STEMI and multivessel disease","volume":"20","author":"Scarparo","year":"2024","journal-title":"EuroIntervention"},{"key":"10.1016\/j.tcm.2026.08.011_bib0030","doi-asserted-by":"crossref","unstructured":"Sardella, G., Lucisano, L., Garbo, R., Pennacchi, M., Cavallo, E., Stio, R.E., et al. Single-staged compared with multi-staged PCI in multivessel NSTEMI patients the smile trial. 2016.","DOI":"10.1016\/j.jacc.2015.10.082"},{"key":"10.1016\/j.tcm.2026.08.011_bib0031","doi-asserted-by":"crossref","DOI":"10.1016\/j.ahj.2025.107284","article-title":"Complete revascularization in patients with acute myocardial infarction and multivessel disease: pooled analysis of Kaplan-Meier-derived individual-patient-data","volume":"292","author":"Abdelaziz","year":"2026","journal-title":"Am Heart J"},{"issue":"9","key":"10.1016\/j.tcm.2026.08.011_bib0032","first-page":"717","article-title":"Revascularization strategies for patients with myocardial infarction and multi-vessel disease: a critical appraisal of the current evidence","volume":"16","author":"Zaman","year":"2019","journal-title":"J Geriatr Cardiol"},{"key":"10.1016\/j.tcm.2026.08.011_bib0033","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1016\/j.xjon.2024.04.009","article-title":"The effect of treatment timing on repeat revascularization in patients with stable ischemic heart disease","volume":"19","author":"Hardiman","year":"2024","journal-title":"JTCVS Open"},{"issue":"19","key":"10.1016\/j.tcm.2026.08.011_bib0034","doi-asserted-by":"crossref","first-page":"1877","DOI":"10.1016\/j.jcin.2019.04.055","article-title":"Procedural strategies to reduce the incidence of contrast-induced acute kidney injury during percutaneous coronary intervention","volume":"12","author":"Almendarez","year":"2019","journal-title":"JACC Cardiovasc Interv"},{"key":"10.1016\/j.tcm.2026.08.011_bib0035","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/j.amjcard.2025.01.029","article-title":"Association of coronary revascularization modality and timing with outcomes of acute coronary syndrome in kidney transplant recipients","volume":"242","author":"Kwon","year":"2025","journal-title":"Am J Cardiol"},{"issue":"3","key":"10.1016\/j.tcm.2026.08.011_bib0036","first-page":"e4","article-title":"2021 ACC\/AHA\/SCAI guideline for coronary artery revascularization: executive summary: a report of the american college of cardiology\/american heart association joint committee on clinical practice guidelines","volume":"145","author":"Lawton","year":"2022","journal-title":"Circulation"},{"key":"10.1016\/j.tcm.2026.08.011_bib0037","doi-asserted-by":"crossref","DOI":"10.15420\/icr.2024.39","article-title":"Complete revascularisation following acute MI: a contemporary review","volume":"20","author":"Gonnah","year":"2025","journal-title":"Interv Cardiol"},{"issue":"20","key":"10.1016\/j.tcm.2026.08.011_bib0038","doi-asserted-by":"crossref","first-page":"1661","DOI":"10.1161\/CIRCULATIONAHA.119.040631","article-title":"Assessment and treatment of patients with type 2 myocardial infarction and acute nonischemic myocardial injury","volume":"140","author":"DeFilippis","year":"2019","journal-title":"Circulation"},{"issue":"13","key":"10.1016\/j.tcm.2026.08.011_bib0039","doi-asserted-by":"crossref","DOI":"10.3390\/jcm12134550","article-title":"Moving toward precision medicine in acute coronary syndromes: a multimodal assessment of non-culprit lesions","volume":"12","author":"Bellino","year":"2023","journal-title":"J Clin Med"},{"issue":"3","key":"10.1016\/j.tcm.2026.08.011_bib0040","doi-asserted-by":"crossref","first-page":"193","DOI":"10.4244\/EIJ-D-20-00957","article-title":"Completeness of revascularisation in acute coronary syndrome patients with multivessel disease","volume":"17","author":"Paradies","year":"2021","journal-title":"EuroIntervention"},{"issue":"19","key":"10.1016\/j.tcm.2026.08.011_bib0041","doi-asserted-by":"crossref","first-page":"2347","DOI":"10.1016\/j.jcin.2023.07.043","article-title":"Complete percutaneous coronary revascularization in acute coronary syndromes with multivessel coronary disease: a systematic review","volume":"16","author":"Faro","year":"2023","journal-title":"JACC Cardiovasc Interv"},{"issue":"2","key":"10.1016\/j.tcm.2026.08.011_bib0042","first-page":"174","article-title":"An overview of PCI in the very elderly","volume":"12","author":"Shanmugam","year":"2015","journal-title":"J Geriatr Cardiol"},{"issue":"12","key":"10.1016\/j.tcm.2026.08.011_bib0043","doi-asserted-by":"crossref","DOI":"10.1002\/clc.70224","article-title":"Nuanced considerations in immediate versus staged multivessel pci: implications for clinical practice and guideline development","volume":"48","author":"Muhammad","year":"2025","journal-title":"Clin Cardiol"},{"issue":"9","key":"10.1016\/j.tcm.2026.08.011_bib0044","doi-asserted-by":"crossref","DOI":"10.3390\/jcdd12090344","article-title":"Personalized treatment of patients with coronary artery disease: the value and limitations of predictive models","volume":"12","author":"Greco","year":"2025","journal-title":"J Cardiovasc Dev Dis"},{"key":"10.1016\/j.tcm.2026.08.011_bib0045","doi-asserted-by":"crossref","DOI":"10.1161\/CIRCINTERVENTIONS.126.016601","article-title":"Timing of complete revascularization in patients with STEMI and multivessel disease: an updated meta-analysis of randomized clinical trials","volume":"19","author":"Elbahloul","year":"2026","journal-title":"Circ Cardiovasc Interv"}],"container-title":["Trends in Cardiovascular Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1050173826001106?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1050173826001106?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,9,5]],"date-time":"2026-09-05T03:55:19Z","timestamp":1788580519000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1050173826001106"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8]]},"references-count":45,"alternative-id":["S1050173826001106"],"URL":"https:\/\/doi.org\/10.1016\/j.tcm.2026.08.011","relation":{},"ISSN":["1050-1738"],"issn-type":[{"value":"1050-1738","type":"print"}],"subject":[],"published":{"date-parts":[[2026,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Immediate versus staged complete revascularization in patients presenting with acute myocardial infarction and multivessel coronary artery disease: A meta-analysis with time-to-event analysis","name":"articletitle","label":"Article Title"},{"value":"Trends in Cardiovascular Medicine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.tcm.2026.08.011","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}