{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T14:04:05Z","timestamp":1791295445984,"version":"4.1.0"},"reference-count":62,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2005,5,1]],"date-time":"2005-05-01T00:00:00Z","timestamp":1114905600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Trends in Endocrinology & Metabolism"],"published-print":{"date-parts":[[2005,5]]},"DOI":"10.1016\/j.tem.2005.03.006","type":"journal-article","created":{"date-parts":[[2005,4,7]],"date-time":"2005-04-07T21:50:54Z","timestamp":1112910654000},"page":"167-175","source":"Crossref","is-referenced-by-count":120,"title":["Multiple functions of type 10 17\u03b2-hydroxysteroid dehydrogenase"],"prefix":"10.1016","volume":"16","author":[{"given":"Song-Yu","family":"Yang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xue-Ying","family":"He","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Horst","family":"Schulz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.tem.2005.03.006_bib1","doi-asserted-by":"crossref","first-page":"10741","DOI":"10.1074\/jbc.273.17.10741","article-title":"A human brain L-3-hydroxyacyl-coenzyme A dehydrogenase is identical to an amyloid \u03b2-peptide-binding protein involved in Alzheimer's disease","volume":"273","author":"He","year":"1998","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.tem.2005.03.006_bib2","doi-asserted-by":"crossref","first-page":"15014","DOI":"10.1074\/jbc.274.21.15014","article-title":"Human brain short chain L-3-hydroxyacyl coenzyme A dehydrogenase is a single-domain multifunctional enzyme. Characterization of a novel 17\u03b2-hydroxysteroid dehydrogenase","volume":"274","author":"He","year":"1999","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.tem.2005.03.006_bib3","doi-asserted-by":"crossref","first-page":"214","DOI":"10.1006\/abbi.1995.1388","article-title":"Short-chain 3-hydroxy-2-methylacyl-CoA dehydrogenase from rat liver: purification and characterization of a novel enzyme of isoleucine metabolism","volume":"321","author":"Luo","year":"1995","journal-title":"Arch. Biochem. Biophys."},{"key":"10.1016\/j.tem.2005.03.006_bib4","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1016\/S0303-7207(00)00391-9","article-title":"Molecular cloning, modeling, and localization of rat type 10 17\u03b2-hydroxysteroid dehydrogenase","volume":"171","author":"He","year":"2001","journal-title":"Mol. Cell. Endocrinol."},{"key":"10.1016\/j.tem.2005.03.006_bib5","doi-asserted-by":"crossref","first-page":"1300","DOI":"10.1086\/375116","article-title":"2-Methyl-3-hydroxybutyryl-CoA dehydrogenase deficiency is caused by mutations in the HADH2 gene","volume":"72","author":"Ofman","year":"2003","journal-title":"Am. J. Hum. Genet."},{"key":"10.1016\/j.tem.2005.03.006_bib6","doi-asserted-by":"crossref","first-page":"775","DOI":"10.1093\/oxfordjournals.jbchem.a021307","article-title":"Two mitochondrial 3-hydroxyacyl-CoA dehydrogenases in bovine liver","volume":"119","author":"Kobayashi","year":"1996","journal-title":"J. Biochem. (Tokyo)"},{"key":"10.1016\/j.tem.2005.03.006_bib7","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1016\/S0167-4781(96)00171-6","article-title":"Cloning and expression of cDNA for a newly identified isoenzyme of bovine liver 3-hydroxyacyl-CoA dehydrogenase and its import into mitochondria","volume":"1350","author":"Furuta","year":"1997","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.tem.2005.03.006_bib8","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1046\/j.1432-1327.1998.2580053.x","article-title":"The gene for the Alzheimer-associated \u03b2-amyloid-binding protein (ERAB) is differentially expressed in the testicular Leydig cells of the azoospermic W\/Wv mouse","volume":"258","author":"Hansis","year":"1998","journal-title":"Eur. J. Biochem."},{"key":"10.1016\/j.tem.2005.03.006_bib9","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1016\/S0169-328X(02)00102-X","article-title":"Abundant type 10 17\u03b2-hydroxysteroid dehydrogenase in the hippocampus of mouse Alzheimer's disease model","volume":"99","author":"He","year":"2002","journal-title":"Brain Res. Mol. Brain Res."},{"key":"10.1016\/j.tem.2005.03.006_bib10","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1023\/A:1021251202287","article-title":"2-Methyl-3-hydroxybutyryl-CoA dehydrogenase deficiency in a 23 year-old man","volume":"25","author":"Olpin","year":"2002","journal-title":"J. Inherit. Metab. Dis."},{"key":"10.1016\/j.tem.2005.03.006_bib11","doi-asserted-by":"crossref","first-page":"656","DOI":"10.1002\/ana.10169","article-title":"Clinical variability in 3-hydroxy-2-methylbutyryl-CoA dehydrogenase deficiency","volume":"51","author":"Ensenauer","year":"2002","journal-title":"Ann. Neurol."},{"key":"10.1016\/j.tem.2005.03.006_bib12","doi-asserted-by":"crossref","first-page":"1009","DOI":"10.1083\/jcb.141.4.1009","article-title":"scully, an essential gene of Drosophila, is homologous to mammalian mitochondrial type II L-3-hydroxyacyl-CoA dehydrogenase\/amyloid-\u03b2 peptide-binding protein","volume":"141","author":"Torroja","year":"1998","journal-title":"J. Cell Biol."},{"key":"10.1016\/j.tem.2005.03.006_bib13","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1042\/bj20030877","article-title":"Expended substrate screenings of human and Drosophila type 10 17\u03b2-hydroxysteroid dehydrogenase reveal multiple specificities in bile acid and steroid hormone metabolism. Characterization of multifunctional 3\u03b1\/7\u03b1\/7\u03b2\/20\u03b2\/21-hydroxysteroid dehydrogenase","volume":"376","author":"Shafqat","year":"2003","journal-title":"Biochem. J."},{"key":"10.1016\/j.tem.2005.03.006_bib14","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1042\/0264-6021:3450139","article-title":"Intrinsic alcohol dehydrogenase and hydroxysteroid dehydrogenase activities of human mitochondrial short chain L-3-hydroxyacyl-CoA dehydrogenase","volume":"345","author":"He","year":"2000","journal-title":"Biochem. J."},{"key":"10.1016\/j.tem.2005.03.006_bib15","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1016\/S1388-1981(00)00014-7","article-title":"Function of human brain short chain L-3-hydroxyacyl coenzyme A dehydrogenase in androgen metabolism","volume":"1484","author":"He","year":"2000","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.tem.2005.03.006_bib16","doi-asserted-by":"crossref","first-page":"4899","DOI":"10.1046\/j.0014-2956.2001.02421.2421.x","article-title":"Characterization and localization of human type 10 17\u03b2-hydroxysteroid dehydrogenase","volume":"268","author":"He","year":"2001","journal-title":"Eur. J. Biochem."},{"key":"10.1016\/j.tem.2005.03.006_bib17","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1006\/jmbi.2000.4139","article-title":"Recognition of structurally diverse substrates by type II 3-hydroxyacyl-CoA dehydrogenase (HADH II)\/amyloid-\u03b2 binding alcohol dehydrogenase (ABAD)","volume":"303","author":"Powell","year":"2000","journal-title":"J. Mol. Biol."},{"key":"10.1016\/j.tem.2005.03.006_bib18","doi-asserted-by":"crossref","first-page":"514","DOI":"10.1016\/S1093-3263(00)00098-X","article-title":"Human type 10 17\u03b2-hydroxysteroid dehydrogenase: molecular modeling and substrate docking","volume":"19","author":"Nordling","year":"2001","journal-title":"J. Mol. Graph. Model"},{"key":"10.1016\/j.tem.2005.03.006_bib19","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1016\/S0303-7207(00)00425-1","article-title":"Type 5 17\u03b2-hydroxysteroid dehydrogenase: its role in the formation of androgens in women","volume":"171","author":"Luu-The","year":"2001","journal-title":"Mol. Cell. Endocrinol."},{"key":"10.1016\/j.tem.2005.03.006_bib20","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1016\/S0303-7207(00)00415-9","article-title":"Evolution of 17\u03b2-HSD type 4, a multifunctional protein of \u03b2-oxidation","volume":"171","author":"Britling","year":"2001","journal-title":"Mol. Cell. Endocrinol."},{"key":"10.1016\/j.tem.2005.03.006_bib21","doi-asserted-by":"crossref","first-page":"22664","DOI":"10.1074\/jbc.273.35.22664","article-title":"Characterization of Ke 6, a new 17\u03b2-hydroxysteroid dehydrogenase, and its expression in gonadal tissues","volume":"273","author":"Formitcheva","year":"1998","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.tem.2005.03.006_bib22","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1016\/S0303-7207(00)00414-7","article-title":"Evolution of 17\u03b2-hydroxysteroid dehydrogenases and their role in androgen, estrogen and retinoid action","volume":"171","author":"Baker","year":"2001","journal-title":"Mol. Cell. Endocrinol."},{"key":"10.1016\/j.tem.2005.03.006_bib23","doi-asserted-by":"crossref","first-page":"2154","DOI":"10.1093\/oxfordjournals.molbev.a003761","article-title":"Structure-based phylogenetic analysis of short-chain alcohol dehydrogenases and reclassification of the 17\u03b2-hydroxysteroid dehydrogenase family","volume":"18","author":"Breitling","year":"2001","journal-title":"Mol. Biol. Evol."},{"key":"10.1016\/j.tem.2005.03.006_bib24","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1016\/S0303-7207(00)00389-0","article-title":"Structure and function of 17\u03b2-hydroxysteroid dehydrogenase type 1 and type 2","volume":"171","author":"Vihko","year":"2001","journal-title":"Mol. Cell. Endocrinol."},{"key":"10.1016\/j.tem.2005.03.006_bib25","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0303-7207(00)00383-X","article-title":"A guide to 17\u03b2-hydroxysteroid dehydrogenases","volume":"171","author":"Adamski","year":"2001","journal-title":"Mol. Cell. Endocrinol."},{"key":"10.1016\/j.tem.2005.03.006_bib26","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1016\/j.jsbmb.2003.07.007","article-title":"Oxidative 3\u03b1-hydroxysteroid dehydrogenase activity of human type 10 17\u03b2-hydroxysteroid dehydrogenase","volume":"87","author":"He","year":"2003","journal-title":"J. Steroid Biochem. Mol. Biol."},{"key":"10.1016\/j.tem.2005.03.006_bib27","doi-asserted-by":"crossref","first-page":"30888","DOI":"10.1074\/jbc.273.47.30888","article-title":"Molecular cloning, overexpression, and characterization of steroid-inducible 3\u03b1-hydroxysteroid dehydrogenase\/carbonyl reductase from Comamonas testosteroni. A novel member of the short-chain dehydrogenase\/reductase family","volume":"273","author":"Mobus","year":"1998","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.tem.2005.03.006_bib28","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1007\/978-1-4615-1249-3_8","article-title":"Role of type 10 17\u03b2-hydroxysteroid dehydrogenase in the pathogenesis of Alzheimer's disease","volume":"487","author":"Yang","year":"2001","journal-title":"Adv. Exp. Med. Biol."},{"key":"10.1016\/j.tem.2005.03.006_bib29","doi-asserted-by":"crossref","first-page":"8709","DOI":"10.1073\/pnas.95.15.8709","article-title":"Chromosomal basis of X chromosome inactivation: identification of a multigene domain in Xp11.21\u2013p11.22 that escapes X inactivation","volume":"95","author":"Miller","year":"1998","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.tem.2005.03.006_bib30","doi-asserted-by":"crossref","first-page":"852","DOI":"10.1203\/00006450-200012000-00025","article-title":"Progressive infantile neurodegeneration caused by 2-methyl-3-hydroxybutyryl-CoA dehydrogenase deficiency: a novel inborn error of branched-chain fatty acid and isoleucine metabolism","volume":"48","author":"Zschocke","year":"2000","journal-title":"Pediatr. Res."},{"key":"10.1016\/j.tem.2005.03.006_bib31","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1016\/S0387-7604(03)00071-8","article-title":"2-Methyl-3-hydroxybutyryl-CoA dehydrogenase deficiency: impaired catabolism of isoleucine presenting as neurodegenerative disease","volume":"26","author":"Sass","year":"2004","journal-title":"Brain Dev."},{"key":"10.1016\/j.tem.2005.03.006_bib32","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1023\/A:1024083715568","article-title":"3-Hydroxy-2-methylbutyryl-CoA dehydrogenase deficiency","volume":"26","author":"Sutton","year":"2003","journal-title":"J. Inherit. Metab. Dis."},{"key":"10.1016\/j.tem.2005.03.006_bib33","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1016\/S0009-2797(02)00164-3","article-title":"Short-chain dehydrogenases\/reductases (SDR): the 2002 update","volume":"143-144","author":"Oppermann","year":"2003","journal-title":"Chem. Biol. Interact."},{"key":"10.1016\/j.tem.2005.03.006_bib34","doi-asserted-by":"crossref","first-page":"3130","DOI":"10.1210\/en.2002-0082","article-title":"Differentiation-dependent expression of 17\u03b2-hydroxysteroid dehydrogenase, type 10, in the rodent testis: effect of aging in Leydig cells","volume":"144","author":"Ivell","year":"2003","journal-title":"Endocrinology"},{"key":"10.1016\/j.tem.2005.03.006_bib35","doi-asserted-by":"crossref","first-page":"15959","DOI":"10.1074\/jbc.272.25.15959","article-title":"Expression, cloning and characterization of oxidative17\u03b2- and 3\u03b1-hydroxysteroid dehydrogenases from rat and human prostate","volume":"272","author":"Biswas","year":"1997","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.tem.2005.03.006_bib36","doi-asserted-by":"crossref","first-page":"19778","DOI":"10.1074\/jbc.273.31.19778","article-title":"cDNA cloning and characterization of a new microsomal NAD+-dependent dehydrogenase that oxidizes all-trans-retinol and 3 \u03b1-hydroxysteroids","volume":"273","author":"Gough","year":"1998","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.tem.2005.03.006_bib37","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1016\/S0167-4838(01)00200-X","article-title":"Characterization of the oxidative 3\u03b1-hydroxysteroid dehydrogenase activity of human recombinant 11-cis-retinol dehydrogenase","volume":"1547","author":"Huang","year":"2001","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.tem.2005.03.006_bib38","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1042\/0264-6021:3510067","article-title":"Human 3\u03b1-hydroxysteroid dehydrogenase isoforms (AKR1C1\u2013AKR1C4) of the aldo-keto reductase superfamily: functional plasticity and tissue distribution reveals roles in the inactivation and formation of male and female sex hormones","volume":"361","author":"Penning","year":"2000","journal-title":"Biochem. J."},{"key":"10.1016\/j.tem.2005.03.006_bib39","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1016\/S0960-0760(03)00236-X","article-title":"Structure\u2013function relationships in 3\u03b1-hydroxysteroid dehydrogenases: a comparison of the rat and human isoforms","volume":"85","author":"Penning","year":"2003","journal-title":"J. Steroid Biochem. Mol. Biol."},{"key":"10.1016\/j.tem.2005.03.006_bib40","doi-asserted-by":"crossref","first-page":"841","DOI":"10.1210\/jc.86.2.841","article-title":"Human type 1 and 3 3\u03b1-hydroxysteroid dehydrogenases: different lability and tissue distribution","volume":"86","author":"Dufort","year":"2001","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"10.1016\/j.tem.2005.03.006_bib41","doi-asserted-by":"crossref","first-page":"2922","DOI":"10.1210\/en.2002-0032","article-title":"Human type 3 3\u03b1-hydroxysteroid dehydrogenase (aldo-keto reductase 1C2) and androgen metabolism in prostate cells","volume":"144","author":"Rizner","year":"2003","journal-title":"Endocrinology"},{"key":"10.1016\/j.tem.2005.03.006_bib42","doi-asserted-by":"crossref","first-page":"1608","DOI":"10.1210\/en.141.5.1608","article-title":"Identification of the oxidative 3\u03b1-hydroxysteroid dehydrogenase activity of rat Leydig cells as type II retinal dehydrogenase","volume":"141","author":"Hardy","year":"2000","journal-title":"Endocrinology"},{"key":"10.1016\/j.tem.2005.03.006_bib43","doi-asserted-by":"crossref","first-page":"5275","DOI":"10.1210\/en.140.11.5275","article-title":"Complementary deoxyribonucleic acid cloning and enzymatic characterization of a novel 17\u03b2\/3\u03b1-hydroxysteroid\/retinoid short chain dehydrogenase\/reductase","volume":"140","author":"Su","year":"1999","journal-title":"Endocrinology"},{"key":"10.1016\/j.tem.2005.03.006_bib44","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1016\/j.mce.2004.08.011","article-title":"Type 10 17\u03b2-hydroxysteroid dehydrogenase catalyzing the oxidation of steroid modulators of \u03b3-aminobutyric acid type A receptors","volume":"229","author":"He","year":"2005","journal-title":"Mol. Cell. Endocrinol."},{"key":"10.1016\/j.tem.2005.03.006_bib45","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1016\/S0165-6147(00)89058-6","article-title":"Neurosteroids and GABAA receptor function","volume":"16","author":"Lambert","year":"1995","journal-title":"Trends Pharmacol. Sci."},{"key":"10.1016\/j.tem.2005.03.006_bib46","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/S1043-2760(01)00503-3","article-title":"Neurosteroids: biochemistry and clinical significance","volume":"13","author":"Mellon","year":"2002","journal-title":"Trends Endocrinol. Metab."},{"key":"10.1016\/j.tem.2005.03.006_bib47","doi-asserted-by":"crossref","first-page":"13512","DOI":"10.1073\/pnas.96.23.13512","article-title":"Selective serotonin reuptake inhibitors directly alter activity of neurosteroidogenic enzymes","volume":"96","author":"Griffin","year":"1999","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.tem.2005.03.006_bib48","doi-asserted-by":"crossref","first-page":"13451","DOI":"10.1021\/bi026109w","article-title":"Kinetics of allopregnanolone formation catalyzed by human 3\u03b1-hydroxysteroid dehydrogenase type III (AKR1C2)","volume":"41","author":"Trauger","year":"2002","journal-title":"Biochemistry"},{"key":"10.1016\/j.tem.2005.03.006_bib49","doi-asserted-by":"crossref","first-page":"2849","DOI":"10.1073\/pnas.051628598","article-title":"Brain 5\u03b1-dihydroprogesterone and allopregnanolone synthesis in a mouse model of protracted social isolation","volume":"98","author":"Dong","year":"2001","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.tem.2005.03.006_bib50","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1016\/S0165-0173(01)00123-0","article-title":"Neuroactive steroids: molecular mechanisms of action and implications for neuropsychopharmacology","volume":"37","author":"Rupprecht","year":"2001","journal-title":"Brain Res. Brain Res. Rev."},{"key":"10.1016\/j.tem.2005.03.006_bib51","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/j.brainres.2005.01.022","article-title":"Intracellular oxidation of allopregnanolone by human brain type 10 17\u03b2-hydroxysteroid dehydrogenase","volume":"1040","author":"He","year":"2005","journal-title":"Brain Res."},{"key":"10.1016\/j.tem.2005.03.006_bib52","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/S0165-0173(01)00109-6","article-title":"Biosynthesis and action of neurosteroids","volume":"37","author":"Mellon","year":"2001","journal-title":"Brain Res. Brain Res. Rev."},{"key":"10.1016\/j.tem.2005.03.006_bib53","doi-asserted-by":"crossref","unstructured":"Chetyrkin, S.V. et al. (2001) Characterization of a novel type of human microsomal 3\u03b1-hydroxysteroid dehydrogenases. Unique tissue distribution and catalytic properties. J. Biol. Chem. 276, 22278\u201322286. Epub 2001, Apr 09","DOI":"10.1074\/jbc.M102076200"},{"key":"10.1016\/j.tem.2005.03.006_bib54","doi-asserted-by":"crossref","first-page":"689","DOI":"10.1038\/39522","article-title":"An intracellular protein that binds amyloid-\u03b2 peptide and mediates neurotoxicity in Alzheimer's disease","volume":"389","author":"Yan","year":"1997","journal-title":"Nature"},{"key":"10.1016\/j.tem.2005.03.006_bib55","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1016\/S0014-5793(99)00586-4","article-title":"Binding of amyloid \u03b2-peptide to mitochondrial hydroxyacyl-CoA dehydrogenase (ERAB): regulation of an SDR enzyme activity with implication for apoptosis in Alzheimer's disease","volume":"451","author":"Oppermann","year":"1999","journal-title":"FEBS Lett."},{"key":"10.1016\/j.tem.2005.03.006_bib56","series-title":"A New Regulatory Function in the Nervous System","first-page":"233","article-title":"Gonadal hormone regulation of synaptic plasticity in the brain. What is the mechanism?","author":"McEwen","year":"1999"},{"key":"10.1016\/j.tem.2005.03.006_bib57","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1038\/nm0498-447","article-title":"Estrogen reduces neuronal generation of Alzheimer \u03b2-amyloid peptides","volume":"4","author":"Xu","year":"1998","journal-title":"Nat. Med."},{"key":"10.1016\/j.tem.2005.03.006_bib58","doi-asserted-by":"crossref","first-page":"2145","DOI":"10.1074\/jbc.274.4.2145","article-title":"Role of ERAB\/L-3-hydroxyacyl-coenzyme A dehydrogenase type II activity in A\u03b2-induced cytotoxicity","volume":"274","author":"Yan","year":"1999","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.tem.2005.03.006_bib59","doi-asserted-by":"crossref","first-page":"448","DOI":"10.1126\/science.1091230","article-title":"ABAD directly links A\u03b2 to mitochondrial toxicity in Alzheimer's disease","volume":"304","author":"Lustbader","year":"2004","journal-title":"Science"},{"key":"10.1016\/j.tem.2005.03.006_bib60","doi-asserted-by":"crossref","first-page":"27100","DOI":"10.1016\/S0021-9258(19)61485-7","article-title":"Amyloid \u03b2-peptide-binding alcohol dehydrogenase is a component of the cellular response to nutritional stress","volume":"275","author":"Yan","year":"2000","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.tem.2005.03.006_bib61","doi-asserted-by":"crossref","first-page":"9687","DOI":"10.1021\/bi000274z","article-title":"Phosphotidylcholine activation of human heart (R)-3-hydroxybutyrate dehydrogenase mutants lacking active center sulfhydryls: site-directed mutagenesis of a new recombinant fusion protein","volume":"39","author":"Chelius","year":"2000","journal-title":"Biochemistry"},{"key":"10.1016\/j.tem.2005.03.006_bib62","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1016\/S0006-8993(01)02497-0","article-title":"Deposition of Alzheimer's vascular amyloid-\u03b2 is associated with decreased expression of brain L-3-hydroxyacyl-coenzyme A dehydrogenase (ERAB)","volume":"907","author":"Frackowiak","year":"2001","journal-title":"Brain Res."}],"container-title":["Trends in Endocrinology & Metabolism"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1043276005000706?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1043276005000706?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2021,7,8]],"date-time":"2021-07-08T03:55:27Z","timestamp":1625716527000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1043276005000706"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,5]]},"references-count":62,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2005,5]]}},"alternative-id":["S1043276005000706"],"URL":"https:\/\/doi.org\/10.1016\/j.tem.2005.03.006","relation":{},"ISSN":["1043-2760"],"issn-type":[{"value":"1043-2760","type":"print"}],"subject":[],"published":{"date-parts":[[2005,5]]}}}