{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T21:29:44Z","timestamp":1791581384716,"version":"4.3.4"},"reference-count":86,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2017,2,1]],"date-time":"2017-02-01T00:00:00Z","timestamp":1485907200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.com","cell.com","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","bmn.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Trends in Endocrinology &amp; Metabolism"],"published-print":{"date-parts":[[2017,2]]},"DOI":"10.1016\/j.tem.2016.11.002","type":"journal-article","created":{"date-parts":[[2016,12,5]],"date-time":"2016-12-05T22:00:23Z","timestamp":1480975223000},"page":"143-152","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":126,"title":["Context-Dependent Role of Oxidized Lipids and Lipoproteins in Inflammation"],"prefix":"10.1016","volume":"28","author":[{"given":"Yury I.","family":"Miller","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John Y.-J.","family":"Shyy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.tem.2016.11.002_bib0435","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1016\/0891-5849(91)90192-6","article-title":"Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde and related aldehydes","volume":"11","author":"Esterbauer","year":"1991","journal-title":"Free Radic. Biol. Med."},{"key":"10.1016\/j.tem.2016.11.002_bib0440","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1007\/978-90-481-8622-8_8","article-title":"Lipoprotein modification and macrophage uptake: role of pathologic cholesterol transport in atherogenesis","volume":"51","author":"Miller","year":"2010","journal-title":"Subcell. Biochem."},{"key":"10.1016\/j.tem.2016.11.002_bib0445","doi-asserted-by":"crossref","first-page":"27","DOI":"10.2174\/138161211795049831","article-title":"Oxidative modification of lipoproteins: mechanisms, role in inflammation and potential clinical applications in cardiovascular disease","volume":"17","author":"Tsimikas","year":"2011","journal-title":"Curr. Pharm. Des."},{"key":"10.1016\/j.tem.2016.11.002_bib0450","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1161\/CIRCRESAHA.110.223875","article-title":"Oxidation-specific epitopes are danger associated molecular patterns recognized by pattern recognition receptors of innate immunity","volume":"108","author":"Miller","year":"2011","journal-title":"Circ. Res."},{"key":"10.1016\/j.tem.2016.11.002_bib0455","doi-asserted-by":"crossref","first-page":"426","DOI":"10.1097\/MOL.0b013e328364e85a","article-title":"Oxidation-specific epitopes as targets for biotheranostic applications in humans: biomarkers, molecular imaging and therapeutics","volume":"24","author":"Miller","year":"2013","journal-title":"Curr. Opin. Lipidol."},{"key":"10.1016\/j.tem.2016.11.002_bib0460","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1007\/s00401-014-1263-5","article-title":"Oxidative tissue injury in multiple sclerosis is only partly reflected in experimental disease models","volume":"128","author":"Schuh","year":"2014","journal-title":"Acta Neuropathol."},{"key":"10.1016\/j.tem.2016.11.002_bib0465","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1016\/j.cell.2008.02.043","article-title":"Identification of oxidative stress and Toll-like receptor 4 signaling as a key pathway of acute lung injury","volume":"133","author":"Imai","year":"2008","journal-title":"Cell"},{"key":"10.1016\/j.tem.2016.11.002_bib0470","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1038\/nri.2016.63","article-title":"Innate sensing of oxidation-specific epitopes in health and disease","volume":"16","author":"Binder","year":"2016","journal-title":"Nat. Rev. Immunol."},{"key":"10.1016\/j.tem.2016.11.002_bib0475","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1172\/JCI4533","article-title":"Monoclonal autoantibodies specific for oxidized phospholipids or oxidized phospholipid-protein adducts inhibit macrophage uptake of oxidized low-density lipoproteins","volume":"103","author":"Horkko","year":"1999","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.tem.2016.11.002_bib0480","doi-asserted-by":"crossref","first-page":"1731","DOI":"10.1172\/JCI8472","article-title":"Natural antibodies with the T15 idiotype may act in atherosclerosis, apoptotic clearance, and protective immunity","volume":"105","author":"Shaw","year":"2000","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.tem.2016.11.002_bib0485","doi-asserted-by":"crossref","first-page":"1474","DOI":"10.1016\/S0022-2275(20)30281-9","article-title":"Scavenger receptor class B type I as a receptor for oxidized low density lipoprotein","volume":"42","author":"Gillotte-Taylor","year":"2001","journal-title":"J. Lipid. Res."},{"key":"10.1016\/j.tem.2016.11.002_bib0490","doi-asserted-by":"crossref","first-page":"969","DOI":"10.1194\/jlr.M400496-JLR200","article-title":"Phosphocholine as a pattern recognition ligand for CD36","volume":"46","author":"Boullier","year":"2005","journal-title":"J. Lipid. Res."},{"key":"10.1016\/j.tem.2016.11.002_bib0495","doi-asserted-by":"crossref","first-page":"736","DOI":"10.1038\/nm876","article-title":"Pneumococcal vaccination decreases atherosclerotic lesion formation: molecular mimicry between Streptococcus pneumoniae and oxidized LDL","volume":"9","author":"Binder","year":"2003","journal-title":"Nat. Med."},{"key":"10.1016\/j.tem.2016.11.002_bib0500","doi-asserted-by":"crossref","first-page":"10241","DOI":"10.1074\/jbc.M709006200","article-title":"Cholesteryl ester hydroperoxides are biologically active components of minimally oxidized LDL","volume":"283","author":"Harkewicz","year":"2008","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.tem.2016.11.002_bib0505","doi-asserted-by":"crossref","first-page":"1355","DOI":"10.1161\/CIRCRESAHA.108.192880","article-title":"Lipoprotein accumulation in macrophages via toll-like receptor-4-dependent fluid phase uptake","volume":"104","author":"Choi","year":"2009","journal-title":"Circ. Res."},{"key":"10.1016\/j.tem.2016.11.002_bib0510","doi-asserted-by":"crossref","first-page":"e83145","DOI":"10.1371\/journal.pone.0083145","article-title":"Polyoxygenated cholesterol ester hydroperoxide activates TLR4 and SYK dependent signaling in macrophages","volume":"8","author":"Choi","year":"2013","journal-title":"PLoS ONE"},{"key":"10.1016\/j.tem.2016.11.002_bib0515","doi-asserted-by":"crossref","first-page":"1961","DOI":"10.1016\/j.jacc.2014.01.055","article-title":"Release and capture of bioactive oxidized phospholipids and oxidized cholesteryl esters during percutaneous coronary and peripheral arterial interventions in humans","volume":"63","author":"Ravandi","year":"2014","journal-title":"J. Am. Coll. Cardiol."},{"key":"10.1016\/j.tem.2016.11.002_bib0520","doi-asserted-by":"crossref","first-page":"1561","DOI":"10.1074\/jbc.M209634200","article-title":"Minimally modified LDL binds to CD14, induces macrophage spreading via TLR4\/MD-2, and inhibits phagocytosis of apoptotic cells","volume":"278","author":"Miller","year":"2003","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.tem.2016.11.002_bib0525","doi-asserted-by":"crossref","first-page":"1191","DOI":"10.1038\/nature07830","article-title":"The structural basis of lipopolysaccharide recognition by the TLR4-MD-2 complex","volume":"458","author":"Park","year":"2009","journal-title":"Nature"},{"key":"10.1016\/j.tem.2016.11.002_bib0530","doi-asserted-by":"crossref","first-page":"877","DOI":"10.1016\/j.bbrc.2016.01.126","article-title":"MD-2 binds cholesterol","volume":"470","author":"Choi","year":"2016","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.tem.2016.11.002_bib0535","doi-asserted-by":"crossref","first-page":"ra60","DOI":"10.1126\/scisignal.2005860","article-title":"Toll-like receptor 4 senses oxidative stress mediated by the oxidation of phospholipids in extracellular vesicles","volume":"8","author":"Mancek-Keber","year":"2015","journal-title":"Sci. Signal."},{"key":"10.1016\/j.tem.2016.11.002_bib0540","doi-asserted-by":"crossref","first-page":"342","DOI":"10.1016\/j.cyto.2008.07.010","article-title":"Signalling adaptors used by Toll-like receptors: an update","volume":"43","author":"Kenny","year":"2008","journal-title":"Cytokine"},{"key":"10.1016\/j.tem.2016.11.002_bib0545","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1161\/CIRCRESAHA.108.181040","article-title":"Macrophages generate reactive oxygen species in response to minimally oxidized low-density lipoprotein: Toll-like receptor 4- and Spleen tyrosine kinase-dependent activation of NADPH oxidase 2","volume":"104","author":"Bae","year":"2009","journal-title":"Circ. Res."},{"key":"10.1016\/j.tem.2016.11.002_bib0550","doi-asserted-by":"crossref","first-page":"e32378","DOI":"10.1371\/journal.pone.0032378","article-title":"Spleen tyrosine kinase regulates AP-1 dependent transcriptional response to minimally oxidized LDL","volume":"7","author":"Choi","year":"2012","journal-title":"PLoS ONE"},{"key":"10.1016\/j.tem.2016.11.002_bib0555","doi-asserted-by":"crossref","first-page":"1991","DOI":"10.1161\/ATVBAHA.111.230847","article-title":"The oral spleen tyrosine kinase inhibitor fostamatinib attenuates inflammation and atherogenesis in low-density lipoprotein receptor-deficient mice","volume":"31","author":"Hilgendorf","year":"2011","journal-title":"Arterioscler Thromb. Vasc. Biol."},{"key":"10.1016\/j.tem.2016.11.002_bib0560","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1007\/s00395-016-0535-8","article-title":"Atheroprotection through SYK inhibition fails in established disease when local macrophage proliferation dominates lesion progression","volume":"111","author":"Lindau","year":"2016","journal-title":"Basic Res. Cardiol."},{"key":"10.1016\/j.tem.2016.11.002_bib0565","first-page":"1921","article-title":"Mice that exclusively express TLR4 on endothelial cells can efficiently clear a lethal systemic Gram-negative bacterial infection","volume":"119","author":"Andonegui","year":"2009","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.tem.2016.11.002_bib0570","doi-asserted-by":"crossref","first-page":"778","DOI":"10.1161\/CIRCRESAHA.111.256859","article-title":"Role of phospholipid oxidation products in atherosclerosis","volume":"111","author":"Lee","year":"2012","journal-title":"Circ. Res."},{"key":"10.1016\/j.tem.2016.11.002_bib0575","doi-asserted-by":"crossref","first-page":"993","DOI":"10.1194\/jlr.R400001-JLR200","article-title":"Thematic review series: the pathogenesis of atherosclerosis. The oxidation hypothesis of atherogenesis: the role of oxidized phospholipids and HDL","volume":"45","author":"Navab","year":"2004","journal-title":"J. Lipid. Res."},{"key":"10.1016\/j.tem.2016.11.002_bib0580","doi-asserted-by":"crossref","first-page":"1286","DOI":"10.1016\/j.jacc.2015.01.050","article-title":"Relationship of oxidized phospholipids on apolipoprotein B-100 to cardiovascular outcomes in patients treated with intensive versus moderate atorvastatin therapy: the TNT trial","volume":"65","author":"Byun","year":"2015","journal-title":"J. Am. Coll. Cardiol."},{"key":"10.1016\/j.tem.2016.11.002_bib0585","doi-asserted-by":"crossref","first-page":"1236","DOI":"10.1016\/j.jacc.2015.07.020","article-title":"Oxidized phospholipids, lipoprotein(a), and progression of calcific aortic valve stenosis","volume":"66","author":"Capoulade","year":"2015","journal-title":"J. Am. Coll. Cardiol."},{"key":"10.1016\/j.tem.2016.11.002_bib0590","doi-asserted-by":"crossref","first-page":"1585","DOI":"10.1161\/hq1001.097027","article-title":"Increased transcription of IL-8 in endothelial cells is differentially regulated by TNF-alpha and oxidized phospholipids","volume":"21","author":"Yeh","year":"2001","journal-title":"Arterioscler. Thromb. Vasc. Biol"},{"key":"10.1016\/j.tem.2016.11.002_bib0595","doi-asserted-by":"crossref","first-page":"516","DOI":"10.1161\/01.RES.87.6.516","article-title":"Role for peroxisome proliferator-activated receptor alpha in oxidized phospholipid-induced synthesis of monocyte chemotactic protein-1 and interleukin-8 by endothelial cells","volume":"87","author":"Lee","year":"2000","journal-title":"Circ. Res."},{"key":"10.1016\/j.tem.2016.11.002_bib0600","doi-asserted-by":"crossref","first-page":"642","DOI":"10.1161\/01.RES.0000207394.39249.fc","article-title":"Identification of prostaglandin E2 receptor subtype 2 as a receptor activated by OxPAPC","volume":"98","author":"Li","year":"2006","journal-title":"Circ. Res."},{"key":"10.1016\/j.tem.2016.11.002_bib0605","doi-asserted-by":"crossref","first-page":"3215","DOI":"10.4049\/jimmunol.1002710","article-title":"Human TMEM30a promotes uptake of antitumor and bioactive choline phospholipids into mammalian cells","volume":"186","author":"Chen","year":"2011","journal-title":"J. Immunol."},{"key":"10.1016\/j.tem.2016.11.002_bib0610","doi-asserted-by":"crossref","first-page":"1232","DOI":"10.1126\/science.aaf3036","article-title":"An endogenous caspase-11 ligand elicits interleukin-1 release from living dendritic cells","volume":"352","author":"Zanoni","year":"2016","journal-title":"Science"},{"key":"10.1016\/j.tem.2016.11.002_bib0615","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1038\/nature01023","article-title":"Protective role of phospholipid oxidation products in endotoxin-induced tissue damage","volume":"419","author":"Bochkov","year":"2002","journal-title":"Nature"},{"key":"10.1016\/j.tem.2016.11.002_bib0620","doi-asserted-by":"crossref","first-page":"e27","DOI":"10.1161\/CIRCRESAHA.111.241869","article-title":"Network for activation of human endothelial cells by oxidized phospholipids: a critical role of heme oxygenase 1","volume":"109","author":"Romanoski","year":"2011","journal-title":"Circ. Res."},{"key":"10.1016\/j.tem.2016.11.002_bib0625","doi-asserted-by":"crossref","first-page":"2147","DOI":"10.1084\/jem.20150603","article-title":"Endothelial NOTCH1 is suppressed by circulating lipids and antagonizes inflammation during atherosclerosis","volume":"212","author":"Briot","year":"2015","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.tem.2016.11.002_bib0630","doi-asserted-by":"crossref","first-page":"780","DOI":"10.1161\/01.RES.0000146030.53089.18","article-title":"Role for sterol regulatory element-binding protein in activation of endothelial cells by phospholipid oxidation products","volume":"95","author":"Yeh","year":"2004","journal-title":"Circ. Res."},{"key":"10.1016\/j.tem.2016.11.002_bib0635","doi-asserted-by":"crossref","first-page":"707","DOI":"10.1146\/annurev-immunol-031210-101405","article-title":"The inflammasome NLRs in immunity, inflammation, and associated diseases","volume":"29","author":"Davis","year":"2011","journal-title":"Annu. Rev. Immunol."},{"key":"10.1016\/j.tem.2016.11.002_bib0640","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1038\/nri3452","article-title":"Activation and regulation of the inflammasomes","volume":"13","author":"Latz","year":"2013","journal-title":"Nat. Rev. Immunol."},{"key":"10.1016\/j.tem.2016.11.002_bib0645","doi-asserted-by":"crossref","first-page":"e11765","DOI":"10.1371\/journal.pone.0011765","article-title":"Cholesterol crystals activate the NLRP3 inflammasome in human macrophages: a novel link between cholesterol metabolism and inflammation","volume":"5","author":"Rajamaki","year":"2010","journal-title":"PLoS ONE"},{"key":"10.1016\/j.tem.2016.11.002_bib0650","doi-asserted-by":"crossref","first-page":"1357","DOI":"10.1038\/nature08938","article-title":"NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals","volume":"464","author":"Duewell","year":"2010","journal-title":"Nature"},{"key":"10.1016\/j.tem.2016.11.002_bib0655","doi-asserted-by":"crossref","first-page":"812","DOI":"10.1038\/ni.2639","article-title":"CD36 coordinates NLRP3 inflammasome activation by facilitating intracellular nucleation of soluble ligands into particulate ligands in sterile inflammation","volume":"14","author":"Sheedy","year":"2013","journal-title":"Nat. Immunol."},{"key":"10.1016\/j.tem.2016.11.002_bib0660","doi-asserted-by":"crossref","first-page":"632","DOI":"10.1161\/CIRCULATIONAHA.113.002714","article-title":"Sterol regulatory element binding protein 2 activation of NLRP3 inflammasome in endothelium mediates hemodynamic-induced atherosclerosis susceptibility","volume":"128","author":"Xiao","year":"2013","journal-title":"Circulation"},{"key":"10.1016\/j.tem.2016.11.002_bib0665","doi-asserted-by":"crossref","first-page":"805","DOI":"10.1161\/CIRCULATIONAHA.114.013675","article-title":"Oxidative stress activates endothelial innate immunity via sterol regulatory element binding protein 2 (SREBP2) transactivation of microRNA-92a","volume":"131","author":"Chen","year":"2015","journal-title":"Circulation"},{"key":"10.1016\/j.tem.2016.11.002_bib0670","doi-asserted-by":"crossref","first-page":"804","DOI":"10.1161\/ATVBAHA.115.305282","article-title":"Early hyperlipidemia promotes endothelial activation via a caspase-1-sirtuin 1 pathway","volume":"35","author":"Yin","year":"2015","journal-title":"Arterioscler Thromb. Vasc. Biol."},{"key":"10.1016\/j.tem.2016.11.002_bib0675","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1016\/S0092-8674(00)80213-5","article-title":"The SREBP pathway: regulation of cholesterol metabolism by proteolysis of a membrane-bound transcription factor","volume":"89","author":"Brown","year":"1997","journal-title":"Cell"},{"key":"10.1016\/j.tem.2016.11.002_bib0680","doi-asserted-by":"crossref","first-page":"e67532","DOI":"10.1371\/journal.pone.0067532","article-title":"Activation of sterol regulatory element binding protein and NLRP3 inflammasome in atherosclerotic lesion development in diabetic pigs","volume":"8","author":"Li","year":"2013","journal-title":"PLoS ONE"},{"key":"10.1016\/j.tem.2016.11.002_bib0685","doi-asserted-by":"crossref","first-page":"1173","DOI":"10.1126\/science.aag0366","article-title":"A lipid arsenal to control inflammation","volume":"352","author":"Napier","year":"2016","journal-title":"Science"},{"key":"10.1016\/j.tem.2016.11.002_bib0690","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1182\/blood.V99.1.199","article-title":"Oxidized phospholipids stimulate tissue factor expression in human endothelial cells via activation of ERK\/EGR-1 and Ca(++)\/NFAT","volume":"99","author":"Bochkov","year":"2002","journal-title":"Blood"},{"key":"10.1016\/j.tem.2016.11.002_bib0695","doi-asserted-by":"crossref","first-page":"896","DOI":"10.1016\/j.cell.2015.12.057","article-title":"NF-kappaB restricts inflammasome activation via elimination of damaged mitochondria","volume":"164","author":"Zhong","year":"2016","journal-title":"Cell"},{"key":"10.1016\/j.tem.2016.11.002_bib0700","doi-asserted-by":"crossref","first-page":"24748","DOI":"10.1074\/jbc.M800352200","article-title":"Oxidized phospholipid inhibition of toll-like receptor (TLR) signaling is restricted to TLR2 and TLR4: roles for CD14, LPS-binding protein, and MD2 as targets for specificity of inhibition","volume":"283","author":"Erridge","year":"2008","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.tem.2016.11.002_bib0705","doi-asserted-by":"crossref","first-page":"7706","DOI":"10.4049\/jimmunol.0903594","article-title":"Oxidized phospholipids are more potent antagonists of lipopolysaccharide than inducers of inflammation","volume":"185","author":"Oskolkova","year":"2010","journal-title":"J. Immunol."},{"key":"10.1016\/j.tem.2016.11.002_bib0710","doi-asserted-by":"crossref","first-page":"356","DOI":"10.1161\/ATVBAHA.108.173799","article-title":"Multi-hit inhibition of circulating and cell-associated components of the Toll-like receptor 4 pathway by oxidized phospholipids","volume":"29","author":"von Schlieffen","year":"2009","journal-title":"Arterioscler Thromb. Vasc. Biol."},{"key":"10.1016\/j.tem.2016.11.002_bib0715","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1016\/j.redox.2015.07.008","article-title":"Antioxidant responses and cellular adjustments to oxidative stress","volume":"6","author":"Espinosa-Diez","year":"2015","journal-title":"Redox Biol."},{"key":"10.1016\/j.tem.2016.11.002_bib0720","doi-asserted-by":"crossref","first-page":"989","DOI":"10.1042\/CS20150436","article-title":"Nrf2 in health and disease: current and future clinical implications","volume":"129","author":"Al-Sawaf","year":"2015","journal-title":"Clin. Sci. (Lond)."},{"key":"10.1016\/j.tem.2016.11.002_bib0725","doi-asserted-by":"crossref","first-page":"737","DOI":"10.1161\/CIRCRESAHA.109.215715","article-title":"Identification of a novel macrophage phenotype that develops in response to atherogenic phospholipids via Nrf2","volume":"107","author":"Kadl","year":"2010","journal-title":"Circ. Res."},{"key":"10.1016\/j.tem.2016.11.002_bib0730","doi-asserted-by":"crossref","first-page":"e1","DOI":"10.1161\/CIRCRESAHA.108.176883","article-title":"Nrf2 regulates antioxidant gene expression evoked by oxidized phospholipids in endothelial cells and murine arteries in vivo","volume":"103","author":"Jyrkkanen","year":"2008","journal-title":"Circ. Res."},{"key":"10.1016\/j.tem.2016.11.002_bib0735","doi-asserted-by":"crossref","first-page":"633","DOI":"10.1161\/01.ATV.0000153106.03644.a0","article-title":"Oxidized phospholipids trigger atherogenic inflammation in murine arteries","volume":"25","author":"Furnkranz","year":"2005","journal-title":"Arterioscler Thromb. Vasc. Biol."},{"key":"10.1016\/j.tem.2016.11.002_bib0740","doi-asserted-by":"crossref","first-page":"593","DOI":"10.15252\/emmm.201404702","article-title":"Phospholipid oxidation generates potent anti-inflammatory lipid mediators that mimic structurally related pro-resolving eicosanoids by activating Nrf2","volume":"7","author":"Bretscher","year":"2015","journal-title":"EMBO Mol. Med."},{"key":"10.1016\/j.tem.2016.11.002_bib0745","article-title":"Cyclopentenone-containing oxidized phospholipids and their isoprostanes as pro-resolving mediators of inflammation","author":"Friedli","year":"2016","journal-title":"Biochim. Biophys. Acta."},{"key":"10.1016\/j.tem.2016.11.002_bib0750","doi-asserted-by":"crossref","first-page":"L550","DOI":"10.1152\/ajplung.00248.2014","article-title":"Oxidized phospholipids protect against lung injury and endothelial barrier dysfunction caused by heat-inactivated Staphylococcus aureus","volume":"308","author":"Meliton","year":"2015","journal-title":"Am. J. Physiol. Lung Cell Mol. Physiol."},{"key":"10.1016\/j.tem.2016.11.002_bib0755","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1016\/j.cellsig.2016.02.015","article-title":"Dual role of vinculin in barrier-disruptive and barrier-enhancing endothelial cell responses","volume":"28","author":"Birukova","year":"2016","journal-title":"Cell Signal."},{"key":"10.1016\/j.tem.2016.11.002_bib0760","doi-asserted-by":"crossref","first-page":"430","DOI":"10.1016\/j.atherosclerosis.2013.06.005","article-title":"Inhibition of monocyte chemotaxis by VB-201, a small molecule lecinoxoid, hinders atherosclerosis development in ApoE(-)\/(-) mice","volume":"229","author":"Feige","year":"2013","journal-title":"Atherosclerosis"},{"key":"10.1016\/j.tem.2016.11.002_bib0765","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1111\/cei.12212","article-title":"VB-201, an oxidized phospholipid small molecule, inhibits CD14- and Toll-like receptor-2-dependent innate cell activation and constrains atherosclerosis","volume":"175","author":"Mendel","year":"2014","journal-title":"Clin. Exp. Immunol."},{"key":"10.1016\/j.tem.2016.11.002_bib0770","doi-asserted-by":"crossref","first-page":"2545","DOI":"10.1007\/s10620-016-4159-5","article-title":"Treatment with oxidized phospholipids directly inhibits nonalcoholic steatohepatitis and liver fibrosis without affecting steatosis","volume":"61","author":"Mendel","year":"2016","journal-title":"Dig. Dis. Sci."},{"key":"10.1016\/j.tem.2016.11.002_bib0345","doi-asserted-by":"crossref","first-page":"834","DOI":"10.1016\/j.immuni.2012.03.010","article-title":"12\/15-Lipoxygenase orchestrates the clearance of apoptotic cells and maintains immunologic tolerance","volume":"36","author":"Uderhardt","year":"2012","journal-title":"Immunity"},{"key":"10.1016\/j.tem.2016.11.002_bib0775","doi-asserted-by":"crossref","first-page":"791","DOI":"10.1194\/jlr.M062539","article-title":"Oxidized LDL signals through Rho-GTPase to induce endothelial cell stiffening and promote capillary formation","volume":"57","author":"Oh","year":"2016","journal-title":"J. Lipid. Res."},{"key":"10.1016\/j.tem.2016.11.002_bib0780","doi-asserted-by":"crossref","first-page":"594","DOI":"10.1016\/j.molmed.2016.05.006","article-title":"Oxysterols in metabolic syndrome: from bystander molecules to bioactive lipids","volume":"22","author":"Guillemot-Legris","year":"2016","journal-title":"Trends Mol. Med."},{"key":"10.1016\/j.tem.2016.11.002_bib0785","article-title":"Biological and pathophysiological roles of end-products of DHA oxidation","author":"Yakubenko","year":"2016","journal-title":"Biochim. Biophys. Acta."},{"key":"10.1016\/j.tem.2016.11.002_bib0790","article-title":"Malondialdehyde epitopes as mediators of sterile inflammation","author":"Busch","year":"2016","journal-title":"Biochim. Biophys. Acta."},{"key":"10.1016\/j.tem.2016.11.002_bib0795","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1038\/nature10449","article-title":"Complement factor H binds malondialdehyde epitopes and protects from oxidative stress","volume":"478","author":"Weismann","year":"2011","journal-title":"Nature"},{"key":"10.1016\/j.tem.2016.11.002_bib0800","doi-asserted-by":"crossref","first-page":"834","DOI":"10.1016\/j.freeradbiomed.2011.05.029","article-title":"Specific recognition of malondialdehyde and malondialdehyde acetaldehyde adducts on oxidized LDL and apoptotic cells by complement anaphylatoxin C3a","volume":"51","author":"Veneskoski","year":"2011","journal-title":"Free Radic. Biol. Med."},{"key":"10.1016\/j.tem.2016.11.002_bib0805","doi-asserted-by":"crossref","first-page":"2483","DOI":"10.4049\/jimmunol.1303075","article-title":"Scavenger receptor function of mouse Fcgamma receptor III contributes to progression of atherosclerosis in apolipoprotein E hyperlipidemic mice","volume":"193","author":"Zhu","year":"2014","journal-title":"J. Immunol."},{"key":"10.1016\/j.tem.2016.11.002_bib0810","doi-asserted-by":"crossref","first-page":"9298","DOI":"10.1073\/pnas.1604780113","article-title":"Stabilin-1 expression defines a subset of macrophages that mediate tissue homeostasis and prevent fibrosis in chronic liver injury","volume":"113","author":"Rantakari","year":"2016","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1016\/j.tem.2016.11.002_bib0815","doi-asserted-by":"crossref","first-page":"2137","DOI":"10.1194\/jlr.M053256","article-title":"Atheroprotective immunization with malondialdehyde-modified LDL is hapten specific and dependent on advanced MDA adducts: implications for development of an atheroprotective vaccine","volume":"55","author":"Gonen","year":"2014","journal-title":"J. Lipid. Res."},{"key":"10.1016\/j.tem.2016.11.002_bib0820","doi-asserted-by":"crossref","first-page":"42027","DOI":"10.1074\/jbc.M305460200","article-title":"Carboxyethylpyrrole protein adducts and autoantibodies, biomarkers for age-related macular degeneration","volume":"278","author":"Gu","year":"2003","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.tem.2016.11.002_bib0825","doi-asserted-by":"crossref","first-page":"2618","DOI":"10.1182\/blood-2015-08-664300","article-title":"Novel phosphatidylethanolamine derivatives accumulate in circulation in hyperlipidemic ApoE\u2013\/\u2013mice and activate platelets via TLR2","volume":"127","author":"Biswas","year":"2016","journal-title":"Blood"},{"key":"10.1016\/j.tem.2016.11.002_bib0830","doi-asserted-by":"crossref","first-page":"972","DOI":"10.1038\/nature09421","article-title":"Oxidative stress induces angiogenesis by activating TLR2 with novel endogenous ligands","volume":"467","author":"West","year":"2010","journal-title":"Nature"},{"key":"10.1016\/j.tem.2016.11.002_bib0835","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1161\/CIRCRESAHA.117.305925","article-title":"Receptor-mediated mechanism controlling tissue levels of bioactive lipid oxidation products","volume":"117","author":"Kim","year":"2015","journal-title":"Circ. Res."},{"key":"10.1016\/j.tem.2016.11.002_bib0840","doi-asserted-by":"crossref","first-page":"e88201","DOI":"10.1371\/journal.pone.0088201","article-title":"T cells and macrophages responding to oxidative damage cooperate in pathogenesis of a mouse model of age-related macular degeneration","volume":"9","author":"Cruz-Guilloty","year":"2014","journal-title":"PLoS ONE"},{"key":"10.1016\/j.tem.2016.11.002_bib0845","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1161\/CIRCRESAHA.112.274241","article-title":"Engagement of platelet toll-like receptor 9 by novel endogenous ligands promotes platelet hyperreactivity and thrombosis","volume":"112","author":"Panigrahi","year":"2013","journal-title":"Circ. Res."},{"key":"10.1016\/j.tem.2016.11.002_bib0850","doi-asserted-by":"crossref","first-page":"1187","DOI":"10.1021\/acs.chemrestox.6b00152","article-title":"Efficient quantitative analysis of carboxyalkylpyrrole ethanolamine phospholipids: elevated levels in sickle cell disease blood","volume":"29","author":"Guo","year":"2016","journal-title":"Chem. Res. Toxicol."},{"key":"10.1016\/j.tem.2016.11.002_bib0855","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1161\/CIRCULATIONAHA.116.020838","article-title":"Oxidized phospholipids on lipoprotein(a) elicit arterial wall inflammation and an inflammatory monocyte response in humans","volume":"134","author":"van der Valk","year":"2016","journal-title":"Circulation"}],"container-title":["Trends in Endocrinology &amp; Metabolism"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1043276016301485?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1043276016301485?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2022,7,16]],"date-time":"2022-07-16T09:47:21Z","timestamp":1657964841000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1043276016301485"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,2]]},"references-count":86,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2017,2]]}},"alternative-id":["S1043276016301485"],"URL":"https:\/\/doi.org\/10.1016\/j.tem.2016.11.002","relation":{},"ISSN":["1043-2760"],"issn-type":[{"value":"1043-2760","type":"print"}],"subject":[],"published":{"date-parts":[[2017,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Context-Dependent Role of Oxidized Lipids and Lipoproteins in Inflammation","name":"articletitle","label":"Article Title"},{"value":"Trends in Endocrinology & Metabolism","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.tem.2016.11.002","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}