{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,23]],"date-time":"2025-12-23T18:53:28Z","timestamp":1766516008368,"version":"build-2065373602"},"reference-count":13,"publisher":"Elsevier BV","issue":"12","license":[{"start":{"date-parts":[[2020,12,1]],"date-time":"2020-12-01T00:00:00Z","timestamp":1606780800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,12,1]],"date-time":"2020-12-01T00:00:00Z","timestamp":1606780800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100004972","name":"Arak University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004972","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["bmn.com","cell.com","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Trends in Endocrinology & Metabolism"],"published-print":{"date-parts":[[2020,12]]},"DOI":"10.1016\/j.tem.2020.09.002","type":"journal-article","created":{"date-parts":[[2020,10,12]],"date-time":"2020-10-12T09:33:00Z","timestamp":1602495180000},"page":"890-892","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":22,"title":["Sitagliptin\/Metformin: A New Medical Treatment in Polycystic Ovary Syndrome"],"prefix":"10.1016","volume":"31","author":[{"given":"Delbar","family":"Daneshjou","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Malek","family":"Soleimani Mehranjani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shahrzad","family":"Zadeh Modarres","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohammad Ali","family":"Shariatzadeh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.tem.2020.09.002_bb0005","first-page":"119","article-title":"Co-administration of metformin and N-acetyl cysteine fails to improve clinical manifestations in PCOS individual undergoing ICSI","volume":"8","author":"Cheraghi","year":"2014","journal-title":"Int. J. Fertil. Steril."},{"key":"10.1016\/j.tem.2020.09.002_bb0010","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/j.coemr.2020.02.014","article-title":"Medical treatment and comorbidity in polycystic ovary syndrome \u2013 an updated review","volume":"12","author":"Glintborg","year":"2020","journal-title":"Curr. Opin. Endocrine Metab. Res."},{"key":"10.1016\/j.tem.2020.09.002_bb0015","doi-asserted-by":"crossref","first-page":"1577","DOI":"10.1007\/s00125-017-4342-z","article-title":"The mechanisms of action of metformin","volume":"60","author":"Rena","year":"2017","journal-title":"Diabetologia"},{"key":"10.1016\/j.tem.2020.09.002_bb0020","doi-asserted-by":"crossref","first-page":"605","DOI":"10.1016\/j.fertnstert.2015.01.019","article-title":"Off-label drug use in the treatment of polycystic ovary syndrome","volume":"103","author":"Vitek","year":"2015","journal-title":"Fertil. Steril."},{"key":"10.1016\/j.tem.2020.09.002_bb0025","first-page":"1","article-title":"Women with polycystic ovarian syndrome. A clinical entity with a high risk of developing diabetes mellitus and gestational diabetes: perspectives of an ideal treatment","volume":"2","author":"Paredes Palma","year":"2019","journal-title":"Obes. Bariatric Surg."},{"key":"10.1016\/j.tem.2020.09.002_bb0030","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1530\/EJE-09-0733","article-title":"Metformin: an old medication of new fashion: evolving new molecular mechanisms and clinical implications in polycystic ovary syndrome","volume":"162","author":"Diamanti-Kandarakis","year":"2010","journal-title":"Eur. J. Endocrinol."},{"key":"10.1016\/j.tem.2020.09.002_bb0035","doi-asserted-by":"crossref","first-page":"741","DOI":"10.1111\/cen.13444","article-title":"Dipeptidyl peptidase 4 serum activity and concentration are increased in women with polycystic ovary syndrome","volume":"87","author":"Blauschmidt","year":"2017","journal-title":"Clin. Endocrinol."},{"key":"10.1016\/j.tem.2020.09.002_bb0040","series-title":"Eighth International Congress and Student Festival of Reproductive Medicine","first-page":"85","article-title":"Comparison of sitagliptin and metformin on the anti-mullerian hormone level in infertile women with polycystic ovarian syndrome in IVF cycle","author":"Daneshjou","year":"2019"},{"key":"10.1016\/j.tem.2020.09.002_bb0045","doi-asserted-by":"crossref","first-page":"1878","DOI":"10.3390\/nu11081878","article-title":"Incretin hormones: the link between glycemic index and cardiometabolic diseases","volume":"11","author":"Salvatore","year":"2019","journal-title":"Nutrients"},{"key":"10.1016\/j.tem.2020.09.002_bb0050","doi-asserted-by":"crossref","first-page":"244","DOI":"10.22270\/jddt.v9i4-s.3261","article-title":"Sitagliptin recuperates oxidative stress and inflammatory cytokine expression in ovary of PCOS rats","volume":"9","author":"Carani","year":"2019","journal-title":"J. Drug Deliv. Ther."},{"key":"10.1016\/j.tem.2020.09.002_bb0055","doi-asserted-by":"crossref","first-page":"743","DOI":"10.2147\/VHRM.S3105","article-title":"New combination treatments in the management of diabetes: focus on sitagliptin\u2013metformin","volume":"4","author":"Green","year":"2008","journal-title":"Vasc. Health Risk Manag."},{"key":"10.1016\/j.tem.2020.09.002_bb0060","doi-asserted-by":"crossref","first-page":"2538","DOI":"10.1080\/15384101.2019.1652036","article-title":"Metformin and sitagliptin combination therapy ameliorates polycystic ovary syndrome with insulin resistance through upregulation of lncRNA H19","volume":"18","author":"Wang","year":"2019","journal-title":"Cell Cycle"},{"key":"10.1016\/j.tem.2020.09.002_bb0065","doi-asserted-by":"crossref","first-page":"600","DOI":"10.1111\/jog.13847","article-title":"Effects of dipeptidyl peptidase-4 inhibitors on transforming growth factor-\u03b21 signal transduction pathways in the ovarian fibrosis of polycystic ovary syndrome rats","volume":"45","author":"Wang","year":"2019","journal-title":"J. Obstet. Gynaecol. Res."}],"container-title":["Trends in Endocrinology & Metabolism"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1043276020301752?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1043276020301752?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,19]],"date-time":"2025-10-19T20:40:51Z","timestamp":1760906451000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1043276020301752"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,12]]},"references-count":13,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2020,12]]}},"alternative-id":["S1043276020301752"],"URL":"https:\/\/doi.org\/10.1016\/j.tem.2020.09.002","relation":{},"ISSN":["1043-2760"],"issn-type":[{"type":"print","value":"1043-2760"}],"subject":[],"published":{"date-parts":[[2020,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Sitagliptin\/Metformin: A New Medical Treatment in Polycystic Ovary Syndrome","name":"articletitle","label":"Article Title"},{"value":"Trends in Endocrinology & Metabolism","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.tem.2020.09.002","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}