{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T03:53:46Z","timestamp":1792036426414,"version":"4.4.0"},"reference-count":228,"publisher":"Elsevier BV","issue":"12","license":[{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,4,19]],"date-time":"2024-04-19T00:00:00Z","timestamp":1713484800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100000265","name":"UKRI Medical Research Council","doi-asserted-by":"publisher","award":["MCU_12010\/10"],"award-info":[{"award-number":["MCU_12010\/10"]}],"id":[{"id":"10.13039\/501100000265","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.fr","clinicalkey.jp","clinicalkey.es","clinicalkey.com.au","clinicalkey.com","bmn.com","cell.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Trends in Endocrinology &amp; Metabolism"],"published-print":{"date-parts":[[2024,12]]},"DOI":"10.1016\/j.tem.2024.04.015","type":"journal-article","created":{"date-parts":[[2024,5,17]],"date-time":"2024-05-17T00:05:37Z","timestamp":1715904337000},"page":"1026-1049","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":120,"title":["Why cells need iron: a compendium of iron utilisation"],"prefix":"10.1016","volume":"35","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8095-9961","authenticated-orcid":false,"given":"Megan R.","family":"Teh","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5977-6602","authenticated-orcid":false,"given":"Andrew E.","family":"Armitage","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8503-6103","authenticated-orcid":false,"given":"Hal","family":"Drakesmith","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.tem.2024.04.015_bb0005","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1016\/j.jinorgbio.2019.03.013","article-title":"The essential metals for humans: a brief overview","volume":"195","author":"Zoroddu","year":"2019","journal-title":"J. Inorg. Biochem."},{"key":"10.1016\/j.tem.2024.04.015_bb0010","series-title":"Molecular Biology of the Cell","author":"Alberts","year":"2002"},{"key":"10.1016\/j.tem.2024.04.015_bb0015","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1111\/j.1574-6968.1983.tb00504.x","article-title":"Lactobacillus plantarum, an organism not requiring iron","volume":"19","author":"Archibald","year":"1983","journal-title":"FEMS Microb. Lett."},{"key":"10.1016\/j.tem.2024.04.015_bb0020","doi-asserted-by":"crossref","first-page":"1651","DOI":"10.1126\/science.288.5471.1651","article-title":"Lack of a role for iron in the Lyme disease pathogen","volume":"288","author":"Posey","year":"2000","journal-title":"Science"},{"key":"10.1016\/j.tem.2024.04.015_bb0025","doi-asserted-by":"crossref","first-page":"520","DOI":"10.1038\/214520a0","article-title":"Trace element requirements of Lactobacillus acidophilus","volume":"214","author":"Sabine","year":"1967","journal-title":"Nature"},{"key":"10.1016\/j.tem.2024.04.015_bb0030","doi-asserted-by":"crossref","first-page":"1223","DOI":"10.1039\/c8mt00146d","article-title":"The human iron-proteome","volume":"10","author":"Andreini","year":"2018","journal-title":"Metallomics"},{"key":"10.1016\/j.tem.2024.04.015_bb0035","doi-asserted-by":"crossref","first-page":"1721","DOI":"10.1152\/physrev.00008.2013","article-title":"Systemic iron homeostasis","volume":"93","author":"Ganz","year":"2013","journal-title":"Physiol. Rev."},{"key":"10.1016\/j.tem.2024.04.015_bb0040","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1113\/expphysiol.2007.039735","article-title":"Oxygen-binding haem proteins","volume":"93","author":"Wilson","year":"2008","journal-title":"Exp. Physiol."},{"key":"10.1016\/j.tem.2024.04.015_bb0045","first-page":"e713","article-title":"Anaemia Collaborators (2023) Prevalence, years lived with disability, and trends in anaemia burden by severity and cause, 1990-2021: findings from the Global Burden of Disease Study 2021","volume":"10","author":"GBD","year":"2021","journal-title":"Lancet Haematol."},{"key":"10.1016\/j.tem.2024.04.015_bb0050","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1016\/S0140-6736(20)32594-0","article-title":"Iron deficiency","volume":"397","author":"Pasricha","year":"2021","journal-title":"Lancet"},{"key":"10.1016\/j.tem.2024.04.015_bb0055","doi-asserted-by":"crossref","first-page":"969","DOI":"10.1038\/s42255-021-00406-7","article-title":"Hepcidin sequesters iron to sustain nucleotide metabolism and mitochondrial function in colorectal cancer epithelial cells","volume":"3","author":"Schwartz","year":"2021","journal-title":"Nat. Metab."},{"key":"10.1016\/j.tem.2024.04.015_bb0060","doi-asserted-by":"crossref","first-page":"1313","DOI":"10.3389\/fimmu.2020.01313","article-title":"Iron deficiency anemia at time of vaccination predicts decreased vaccine response and iron supplementation at time of vaccination increases humoral vaccine response: a birth cohort study and a randomized trial follow-up study in Kenyan infants","volume":"11","author":"Stoffel","year":"2020","journal-title":"Front. Immunol."},{"key":"10.1016\/j.tem.2024.04.015_bb0065","doi-asserted-by":"crossref","first-page":"969","DOI":"10.1016\/0378-4274(95)03532-X","article-title":"Toxicity of iron and hydrogen peroxide: the Fenton reaction","volume":"82-83","author":"Winterbourn","year":"1995","journal-title":"Toxicol. Lett."},{"key":"10.1016\/j.tem.2024.04.015_bb0070","doi-asserted-by":"crossref","first-page":"768","DOI":"10.1126\/science.1224577","article-title":"Hepcidin and the iron-infection axis","volume":"338","author":"Drakesmith","year":"2012","journal-title":"Science"},{"key":"10.1016\/j.tem.2024.04.015_bb0075","article-title":"Mechanisms controlling cellular and systemic iron homeostasis","author":"Galy","year":"2023","journal-title":"Nat. Rev. Mol. Cell Biol."},{"key":"10.1016\/j.tem.2024.04.015_bb0080","doi-asserted-by":"crossref","first-page":"344","DOI":"10.1016\/j.cell.2016.12.034","article-title":"A red carpet for iron metabolism","volume":"168","author":"Muckenthaler","year":"2017","journal-title":"Cell"},{"key":"10.1016\/j.tem.2024.04.015_bb0085","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1016\/S0300-9084(86)80004-9","article-title":"Receptor-mediated endocytosis: the intracellular journey of transferrin and its receptor","volume":"68","author":"Dautry-Varsat","year":"1986","journal-title":"Biochimie"},{"key":"10.1016\/j.tem.2024.04.015_bb0090","doi-asserted-by":"crossref","first-page":"1148","DOI":"10.1073\/pnas.95.3.1148","article-title":"Nramp2 is mutated in the anemic Belgrade (b) rat: evidence of a role for Nramp2 in endosomal iron transport","volume":"95","author":"Fleming","year":"1998","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.tem.2024.04.015_bb0095","doi-asserted-by":"crossref","first-page":"4406","DOI":"10.1182\/blood.V93.12.4406","article-title":"Cellular and subcellular localization of the Nramp2 iron transporter in the intestinal brush border and regulation by dietary iron","volume":"93","author":"Canonne-Hergaux","year":"1999","journal-title":"Blood"},{"key":"10.1016\/j.tem.2024.04.015_bb0100","doi-asserted-by":"crossref","first-page":"13612","DOI":"10.1073\/pnas.0606424103","article-title":"Zip14 (Slc39a14) mediates non-transferrin-bound iron uptake into cells","volume":"103","author":"Liuzzi","year":"2006","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.tem.2024.04.015_bb0105","doi-asserted-by":"crossref","first-page":"34032","DOI":"10.1074\/jbc.M112.367284","article-title":"ZIP8 is an iron and zinc transporter whose cell-surface expression is up-regulated by cellular iron loading","volume":"287","author":"Wang","year":"2012","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.tem.2024.04.015_bb0110","doi-asserted-by":"crossref","first-page":"929","DOI":"10.1038\/s41557-020-0513-5","article-title":"CD44 regulates epigenetic plasticity by mediating iron endocytosis","volume":"12","author":"M\u00fcller","year":"2020","journal-title":"Nat. Chem."},{"key":"10.1016\/j.tem.2024.04.015_bb0115","doi-asserted-by":"crossref","first-page":"176","DOI":"10.3389\/fphar.2014.00176","article-title":"The IRP\/IRE system in vivo: insights from mouse models","volume":"5","author":"Wilkinson","year":"2014","journal-title":"Front. Pharmacol."},{"key":"10.1016\/j.tem.2024.04.015_bb0120","doi-asserted-by":"crossref","first-page":"458","DOI":"10.1016\/S0022-2836(65)80196-6","article-title":"An x-ray scattering study of ferritin and apoferritin","volume":"14","author":"Fischbach","year":"1965","journal-title":"J. Mol. Biol."},{"key":"10.1016\/j.tem.2024.04.015_bb0125","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1038\/nature13148","article-title":"Quantitative proteomics identifies NCOA4 as the cargo receptor mediating ferritinophagy","volume":"509","author":"Mancias","year":"2014","journal-title":"Nature"},{"key":"10.1016\/j.tem.2024.04.015_bb0130","doi-asserted-by":"crossref","first-page":"12764","DOI":"10.1074\/jbc.R117.791962","article-title":"Cytosolic iron chaperones: proteins delivering iron cofactors in the cytosol of mammalian cells","volume":"292","author":"Philpott","year":"2017","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.tem.2024.04.015_bb0135","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1038\/s41586-019-1774-2","article-title":"PGRMC2 is an intracellular haem chaperone critical for adipocyte function","volume":"576","author":"Galmozzi","year":"2019","journal-title":"Nature"},{"key":"10.1016\/j.tem.2024.04.015_bb0140","doi-asserted-by":"crossref","first-page":"776","DOI":"10.1038\/35001596","article-title":"Positional cloning of zebrafish ferroportin1 identifies a conserved vertebrate iron exporter","volume":"403","author":"Donovan","year":"2000","journal-title":"Nature"},{"key":"10.1016\/j.tem.2024.04.015_bb0145","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1016\/S1097-2765(00)80425-6","article-title":"A novel duodenal iron-regulated transporter, IREG1, implicated in the basolateral transfer of iron to the circulation","volume":"5","author":"McKie","year":"2000","journal-title":"Mol. Cell"},{"key":"10.1016\/j.tem.2024.04.015_bb0150","doi-asserted-by":"crossref","first-page":"19906","DOI":"10.1074\/jbc.M000713200","article-title":"A novel mammalian iron-regulated protein involved in intracellular iron metabolism","volume":"275","author":"Abboud","year":"2000","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.tem.2024.04.015_bb0155","doi-asserted-by":"crossref","first-page":"1324","DOI":"10.1073\/pnas.0409409102","article-title":"Iron release from macrophages after erythrophagocytosis is up-regulated by ferroportin 1 overexpression and down-regulated by hepcidin","volume":"102","author":"Knutson","year":"2005","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.tem.2024.04.015_bb0160","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1007\/s10534-015-9841-0","article-title":"Lessons from bloodless worms: heme homeostasis in C. elegans","volume":"28","author":"Sinclair","year":"2015","journal-title":"Biometals"},{"key":"10.1016\/j.tem.2024.04.015_bb0165","doi-asserted-by":"crossref","first-page":"1008","DOI":"10.1016\/j.cmet.2014.03.030","article-title":"Control of metazoan heme homeostasis by a conserved multidrug resistance protein","volume":"19","author":"Korolnek","year":"2014","journal-title":"Cell Metab."},{"key":"10.1016\/j.tem.2024.04.015_bb0170","doi-asserted-by":"crossref","first-page":"15649","DOI":"10.1073\/pnas.202607599","article-title":"The breast cancer resistance protein protects against a major chlorophyll-derived dietary phototoxin and protoporphyria","volume":"99","author":"Jonker","year":"2002","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.tem.2024.04.015_bb0175","doi-asserted-by":"crossref","first-page":"722","DOI":"10.1126\/science.1176326","article-title":"An E3 ligase possessing an iron-responsive hemerythrin domain is a regulator of iron homeostasis","volume":"326","author":"Salahudeen","year":"2009","journal-title":"Science"},{"key":"10.1016\/j.tem.2024.04.015_bb0180","doi-asserted-by":"crossref","first-page":"718","DOI":"10.1126\/science.1176333","article-title":"Control of iron homeostasis by an iron-regulated ubiquitin ligase","volume":"326","author":"Vashisht","year":"2009","journal-title":"Science"},{"key":"10.1016\/j.tem.2024.04.015_bb0185","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1042\/BJ20101825","article-title":"Regulation of cellular iron metabolism","volume":"434","author":"Wang","year":"2011","journal-title":"Biochem. J."},{"key":"10.1016\/j.tem.2024.04.015_bb0190","doi-asserted-by":"crossref","first-page":"1903","DOI":"10.1002\/j.1460-2075.1991.tb07716.x","article-title":"Identification of a novel iron-responsive element in murine and human erythroid delta-aminolevulinic acid synthase mRNA","volume":"10","author":"Dandekar","year":"1991","journal-title":"EMBO J."},{"key":"10.1016\/j.tem.2024.04.015_bb0195","doi-asserted-by":"crossref","first-page":"4925","DOI":"10.1073\/pnas.93.10.4925","article-title":"Translational regulation of mammalian and Drosophila citric acid cycle enzymes via iron-responsive elements","volume":"93","author":"Gray","year":"1996","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.tem.2024.04.015_bb0200","doi-asserted-by":"crossref","first-page":"630","DOI":"10.1053\/j.gastro.2013.12.031","article-title":"Hypoxia-inducible factors link iron homeostasis and erythropoiesis","volume":"146","author":"Shah","year":"2014","journal-title":"Gastroenterology"},{"key":"10.1016\/j.tem.2024.04.015_bb0205","doi-asserted-by":"crossref","first-page":"573","DOI":"10.1038\/s41581-022-00587-8","article-title":"The effect of HIF on metabolism and immunity","volume":"18","author":"Taylor","year":"2022","journal-title":"Nat. Rev. Nephrol."},{"key":"10.1016\/j.tem.2024.04.015_bb0210","doi-asserted-by":"crossref","first-page":"864","DOI":"10.1002\/jcb.24423","article-title":"Differential in vitro and cellular effects of iron chelators for hypoxia inducible factor hydroxylases","volume":"114","author":"Cho","year":"2013","journal-title":"J. Cell. Biochem."},{"key":"10.1016\/j.tem.2024.04.015_bb0215","doi-asserted-by":"crossref","first-page":"556","DOI":"10.1002\/jat.3749","article-title":"The use of cobalt chloride as a chemical hypoxia model","volume":"39","author":"Mu\u00f1oz-S\u00e1nchez","year":"2019","journal-title":"J. Appl. Toxicol."},{"key":"10.1016\/j.tem.2024.04.015_bb0220","doi-asserted-by":"crossref","first-page":"2693","DOI":"10.1182\/blood-2006-08-041830","article-title":"Regulation of protein synthesis by the heme-regulated eIF2alpha kinase: relevance to anemias","volume":"109","author":"Chen","year":"2007","journal-title":"Blood"},{"key":"10.1016\/j.tem.2024.04.015_bb0225","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1038\/s41586-020-2076-4","article-title":"A pathway coordinated by DELE1 relays mitochondrial stress to the cytosol","volume":"579","author":"Fessler","year":"2020","journal-title":"Nature"},{"key":"10.1016\/j.tem.2024.04.015_bb0230","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1038\/s41586-020-2078-2","article-title":"Mitochondrial stress is relayed to the cytosol by an OMA1-DELE1-HRI pathway","volume":"579","author":"Guo","year":"2020","journal-title":"Nature"},{"key":"10.1016\/j.tem.2024.04.015_bb0235","doi-asserted-by":"crossref","DOI":"10.1126\/science.aaw4144","article-title":"The heme-regulated inhibitor is a cytosolic sensor of protein misfolding that controls innate immune signaling","volume":"365","author":"Abdel-Nour","year":"2019","journal-title":"Science"},{"key":"10.1016\/j.tem.2024.04.015_bb0240","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1016\/j.cell.2004.11.032","article-title":"Coordinated remodeling of cellular metabolism during iron deficiency through targeted mRNA degradation","volume":"120","author":"Puig","year":"2005","journal-title":"Cell"},{"key":"10.1016\/j.tem.2024.04.015_bb0245","doi-asserted-by":"crossref","first-page":"645","DOI":"10.1016\/j.cmet.2012.10.001","article-title":"mTOR regulates cellular iron homeostasis through tristetraprolin","volume":"16","author":"Bayeva","year":"2012","journal-title":"Cell Metab."},{"key":"10.1016\/j.tem.2024.04.015_bb0250","doi-asserted-by":"crossref","first-page":"E6291","DOI":"10.1073\/pnas.1804701115","article-title":"mRNA-binding protein tristetraprolin is essential for cardiac response to iron deficiency by regulating mitochondrial function","volume":"115","author":"Sato","year":"2018","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.tem.2024.04.015_bb0255","doi-asserted-by":"crossref","first-page":"1478","DOI":"10.1038\/s41556-023-01225-6","article-title":"Iron drives anabolic metabolism through active histone demethylation and mTORC1","volume":"25","author":"Shapiro","year":"2023","journal-title":"Nat. Cell Biol."},{"key":"10.1016\/j.tem.2024.04.015_bb0260","doi-asserted-by":"crossref","first-page":"322","DOI":"10.1038\/s42003-020-1048-4","article-title":"The iron-sulphur cluster in human DNA2 is required for all biochemical activities of DNA2","volume":"3","author":"Mariotti","year":"2020","journal-title":"Commun. Biol."},{"key":"10.1016\/j.tem.2024.04.015_bb0265","doi-asserted-by":"crossref","first-page":"33444","DOI":"10.1074\/jbc.M705826200","article-title":"An iron-sulfur cluster in the C-terminal domain of the p58 subunit of human DNA primase","volume":"282","author":"Weiner","year":"2007","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.tem.2024.04.015_bb0270","doi-asserted-by":"crossref","DOI":"10.3389\/fcell.2021.735678","article-title":"Biogenesis of iron-sulfur clusters and their role in DNA metabolism","volume":"9","author":"Shi","year":"2021","journal-title":"Front. Cell Dev. Biol."},{"key":"10.1016\/j.tem.2024.04.015_bb0275","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1016\/S0021-9258(17)37922-X","article-title":"Human amidophosphoribosyltransferase. An oxygen-sensitive iron-sulfur protein","volume":"254","author":"Itakura","year":"1979","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.tem.2024.04.015_bb0280","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1016\/S1367-5931(03)00025-5","article-title":"Di-iron-tyrosyl radical ribonucleotide reductases","volume":"7","author":"Stubbe","year":"2003","journal-title":"Curr. Opin. Chem. Biol."},{"key":"10.1016\/j.tem.2024.04.015_bb0285","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S1570-9639(04)00054-8","article-title":"Structure, function, and mechanism of ribonucleotide reductases","volume":"1699","author":"Kolberg","year":"2004","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.tem.2024.04.015_bb0290","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1007\/s10534-020-00243-3","article-title":"Iron chelators in cancer therapy","volume":"33","author":"Ibrahim","year":"2020","journal-title":"Biometals"},{"key":"10.1016\/j.tem.2024.04.015_bb0295","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1016\/j.medj.2020.10.004","article-title":"Hepcidin-mediated hypoferremia disrupts immune responses to vaccination and infection","volume":"2","author":"Frost","year":"2021","journal-title":"Med"},{"key":"10.1016\/j.tem.2024.04.015_bb0300","doi-asserted-by":"crossref","first-page":"695","DOI":"10.1038\/372695a0","article-title":"A potent peptidomimetic inhibitor of HSV ribonucleotide reductase with antiviral activity in vivo","volume":"372","author":"Liuzzi","year":"1994","journal-title":"Nature"},{"key":"10.1016\/j.tem.2024.04.015_bb0305","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1126\/science.abi5224","article-title":"Fe-S cofactors in the SARS-CoV-2 RNA-dependent RNA polymerase are potential antiviral targets","volume":"373","author":"Maio","year":"2021","journal-title":"Science"},{"key":"10.1016\/j.tem.2024.04.015_bb0310","doi-asserted-by":"crossref","DOI":"10.1073\/pnas.2303860120","article-title":"An iron-sulfur cluster in the zinc-binding domain of the SARS-CoV-2 helicase modulates its RNA-binding and -unwinding activities","volume":"120","author":"Maio","year":"2023","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.tem.2024.04.015_bb0315","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1038\/nrmicro1930","article-title":"Viral infection and iron metabolism","volume":"6","author":"Drakesmith","year":"2008","journal-title":"Nat. Rev. Microbiol."},{"key":"10.1016\/j.tem.2024.04.015_bb0320","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pgen.1008740","article-title":"Cancer-associated mutations in the iron-sulfur domain of FANCJ affect G-quadruplex metabolism","volume":"16","author":"Odermatt","year":"2020","journal-title":"PLoS Genet."},{"key":"10.1016\/j.tem.2024.04.015_bb0325","doi-asserted-by":"crossref","DOI":"10.26508\/lsa.201900547","article-title":"The iron-sulfur helicase DDX11 promotes the generation of single-stranded DNA for CHK1 activation","volume":"3","author":"Simon","year":"2020","journal-title":"Life Sci. Alliance"},{"key":"10.1016\/j.tem.2024.04.015_bb0330","doi-asserted-by":"crossref","first-page":"801","DOI":"10.1016\/j.molcel.2006.07.019","article-title":"The DNA repair helicases XPD and FancJ have essential iron-sulfur domains","volume":"23","author":"Rudolf","year":"2006","journal-title":"Mol. Cell"},{"key":"10.1016\/j.tem.2024.04.015_bb0335","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1016\/j.tcb.2023.07.002","article-title":"The many faces of the helicase RTEL1 at telomeres and beyond","volume":"34","author":"Hourvitz","year":"2023","journal-title":"Trends Cell Biol."},{"key":"10.1016\/j.tem.2024.04.015_bb0340","doi-asserted-by":"crossref","first-page":"989","DOI":"10.1128\/MCB.15.2.989","article-title":"Characterization of a mammalian homolog of the Escherichia coli MutY mismatch repair protein","volume":"15","author":"McGoldrick","year":"1995","journal-title":"Mol. Cell. Biol."},{"key":"10.1016\/j.tem.2024.04.015_bb0345","doi-asserted-by":"crossref","first-page":"8348","DOI":"10.1093\/nar\/gkz705","article-title":"DNA polymerase \u03b6 in DNA replication and repair","volume":"47","author":"Martin","year":"2019","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.tem.2024.04.015_bb0350","doi-asserted-by":"crossref","first-page":"20734","DOI":"10.1074\/jbc.R115.656462","article-title":"The AlkB family of Fe(II)\/\u03b1-ketoglutarate-dependent dioxygenases: repairing nucleic acid alkylation damage and beyond","volume":"290","author":"Fedeles","year":"2015","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.tem.2024.04.015_bb0355","doi-asserted-by":"crossref","first-page":"94","DOI":"10.3390\/ph11040094","article-title":"Anemia and iron deficiency in cancer patients: role of iron replacement therapy","volume":"11","author":"Busti","year":"2018","journal-title":"Pharmaceuticals (Basel)"},{"key":"10.1016\/j.tem.2024.04.015_bb0360","doi-asserted-by":"crossref","DOI":"10.1038\/emm.2017.11","article-title":"Writing, erasing and reading histone lysine methylations","volume":"49","author":"Hyun","year":"2017","journal-title":"Exp. Mol. Med."},{"key":"10.1016\/j.tem.2024.04.015_bb0365","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1146\/annurev-biochem-061516-044724","article-title":"2-Oxoglutarate-dependent oxygenases","volume":"87","author":"Islam","year":"2018","journal-title":"Annu. Rev. Biochem."},{"key":"10.1016\/j.tem.2024.04.015_bb0370","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1038\/npp.2012.112","article-title":"DNA methylation and its basic function","volume":"38","author":"Moore","year":"2013","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.tem.2024.04.015_bb0375","doi-asserted-by":"crossref","first-page":"6120","DOI":"10.1093\/nar\/gkad342","article-title":"Crucial role of iron in epigenetic rewriting during adipocyte differentiation mediated by JMJD1A and TET2 activity","volume":"51","author":"Suzuki","year":"2023","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.tem.2024.04.015_bb0380","doi-asserted-by":"crossref","first-page":"1737","DOI":"10.1021\/acschembio.9b00289","article-title":"The clinically used iron chelator deferasirox is an inhibitor of epigenetic JumonjiC domain-containing histone demethylases","volume":"14","author":"Roatsch","year":"2019","journal-title":"ACS Chem. Biol."},{"key":"10.1016\/j.tem.2024.04.015_bb0385","doi-asserted-by":"crossref","first-page":"2935","DOI":"10.1038\/s41467-019-11002-5","article-title":"Iron-dependent histone 3 lysine 9 demethylation controls B cell proliferation and humoral immune responses","volume":"10","author":"Jiang","year":"2019","journal-title":"Nat. Commun."},{"key":"10.1016\/j.tem.2024.04.015_bb0390","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2021.714613","article-title":"Analysis of iron and iron-interacting protein dynamics during T-cell activation","volume":"12","author":"Teh","year":"2021","journal-title":"Front. Immunol."},{"key":"10.1016\/j.tem.2024.04.015_bb0395","doi-asserted-by":"crossref","first-page":"2835","DOI":"10.1093\/emboj\/20.11.2835","article-title":"Heme mediates derepression of Maf recognition element through direct binding to transcription repressor Bach1","volume":"20","author":"Ogawa","year":"2001","journal-title":"EMBO J."},{"key":"10.1016\/j.tem.2024.04.015_bb0400","doi-asserted-by":"crossref","first-page":"19911","DOI":"10.1073\/pnas.1905216116","article-title":"Heme binding to human CLOCK affects interactions with the E-box","volume":"116","author":"Freeman","year":"2019","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.tem.2024.04.015_bb0405","doi-asserted-by":"crossref","first-page":"20054","DOI":"10.1074\/jbc.M113.545111","article-title":"Structure of REV-ERB\u03b2 ligand-binding domain bound to a porphyrin antagonist","volume":"289","author":"Matta-Camacho","year":"2014","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.tem.2024.04.015_bb0410","doi-asserted-by":"crossref","first-page":"2385","DOI":"10.1126\/science.1078456","article-title":"NPAS2: a gas-responsive transcription factor","volume":"298","author":"Dioum","year":"2002","journal-title":"Science"},{"key":"10.1016\/j.tem.2024.04.015_bb0415","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1007\/BF02334070","article-title":"Changes in the circadian rhythm of serum iron induced by a 5-day sleep deprivation","volume":"49","author":"Kuhn","year":"1982","journal-title":"Eur. J. Appl. Physiol. Occup. Physiol."},{"key":"10.1016\/j.tem.2024.04.015_bb0420","doi-asserted-by":"crossref","DOI":"10.1111\/cns.14592","article-title":"Cellular iron depletion enhances behavioral rhythm by limiting brain Per1 expression in mice","volume":"30","author":"Wu","year":"2024","journal-title":"CNS Neurosci. Ther."},{"key":"10.1016\/j.tem.2024.04.015_bb0425","doi-asserted-by":"crossref","DOI":"10.1016\/j.expneurol.2022.114158","article-title":"Brain-iron deficiency models of restless legs syndrome","volume":"356","author":"Earley","year":"2022","journal-title":"Exp. Neurol."},{"key":"10.1016\/j.tem.2024.04.015_bb0430","doi-asserted-by":"crossref","DOI":"10.1016\/j.celrep.2020.107895","article-title":"Ribosome recycling by ABCE1 links lysosomal function and iron homeostasis to 3' UTR-directed regulation and nonsense-mediated decay","volume":"32","author":"Zhu","year":"2020","journal-title":"Cell Rep."},{"key":"10.1016\/j.tem.2024.04.015_bb0435","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1038\/nrm.2016.132","article-title":"Post-transcriptional gene regulation by mRNA modifications","volume":"18","author":"Zhao","year":"2017","journal-title":"Nat. Rev. Mol. Cell Biol."},{"key":"10.1016\/j.tem.2024.04.015_bb0440","doi-asserted-by":"crossref","first-page":"684","DOI":"10.1038\/s41556-021-00709-7","article-title":"ALKBH7-mediated demethylation regulates mitochondrial polycistronic RNA processing","volume":"23","author":"Zhang","year":"2021","journal-title":"Nat. Cell Biol."},{"key":"10.1016\/j.tem.2024.04.015_bb0445","doi-asserted-by":"crossref","first-page":"4031","DOI":"10.1073\/pnas.1314482111","article-title":"OGFOD1 catalyzes prolyl hydroxylation of RPS23 and is involved in translation control and stress granule formation","volume":"111","author":"Singleton","year":"2014","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.tem.2024.04.015_bb0450","doi-asserted-by":"crossref","first-page":"1698","DOI":"10.1038\/s41467-023-37305-2","article-title":"Cryo-EM structure of human eIF5A-DHS complex reveals the molecular basis of hypusination-associated neurodegenerative disorders","volume":"14","author":"W\u0105tor","year":"2023","journal-title":"Nat. Commun."},{"key":"10.1016\/j.tem.2024.04.015_bb0455","doi-asserted-by":"crossref","first-page":"8031","DOI":"10.1073\/pnas.1402732111","article-title":"Iron chaperones PCBP1 and PCBP2 mediate the metallation of the dinuclear iron enzyme deoxyhypusine hydroxylase","volume":"111","author":"Frey","year":"2014","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.tem.2024.04.015_bb0460","doi-asserted-by":"crossref","first-page":"1130","DOI":"10.1016\/j.bbamcr.2015.01.021","article-title":"Cellular iron uptake, trafficking and metabolism: key molecules and mechanisms and their roles in disease","volume":"1853","author":"Lane","year":"2015","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.tem.2024.04.015_bb0465","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1182\/blood-2007-01-068148","article-title":"Direct interorganellar transfer of iron from endosome to mitochondrion","volume":"110","author":"Sheftel","year":"2007","journal-title":"Blood"},{"key":"10.1016\/j.tem.2024.04.015_bb0470","doi-asserted-by":"crossref","first-page":"458","DOI":"10.4161\/19336950.2014.956564","article-title":"Mitochondria represent another locale for the divalent metal transporter 1 (DMT1)","volume":"8","author":"Wolff","year":"2014","journal-title":"Channels (Austin)"},{"key":"10.1016\/j.tem.2024.04.015_bb0475","doi-asserted-by":"crossref","first-page":"2134","DOI":"10.1096\/fj.13-240564","article-title":"Evidence for mitochondrial localization of divalent metal transporter 1 (DMT1)","volume":"28","author":"Wolff","year":"2014","journal-title":"FASEB J."},{"key":"10.1016\/j.tem.2024.04.015_bb0480","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1038\/nature04512","article-title":"Mitoferrin is essential for erythroid iron assimilation","volume":"440","author":"Shaw","year":"2006","journal-title":"Nature"},{"key":"10.1016\/j.tem.2024.04.015_bb0485","doi-asserted-by":"crossref","first-page":"1007","DOI":"10.1128\/MCB.01685-08","article-title":"Regulation of mitochondrial iron import through differential turnover of mitoferrin 1 and mitoferrin 2","volume":"29","author":"Paradkar","year":"2009","journal-title":"Mol. Cell. Biol."},{"key":"10.1016\/j.tem.2024.04.015_bb0490","doi-asserted-by":"crossref","first-page":"24437","DOI":"10.1074\/jbc.C100141200","article-title":"A human mitochondrial ferritin encoded by an intronless gene","volume":"276","author":"Levi","year":"2001","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.tem.2024.04.015_bb0495","doi-asserted-by":"crossref","first-page":"783","DOI":"10.1016\/j.bbagen.2010.02.005","article-title":"Cytosolic and mitochondrial ferritins in the regulation of cellular iron homeostasis and oxidative damage","volume":"1800","author":"Arosio","year":"2010","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.tem.2024.04.015_bb0500","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1080\/17474086.2016.1268047","article-title":"Mitochondria and Iron: current questions","volume":"10","author":"Paul","year":"2017","journal-title":"Expert Rev. Hematol."},{"key":"10.1016\/j.tem.2024.04.015_bb0505","doi-asserted-by":"crossref","first-page":"1994","DOI":"10.1182\/blood.2021010835","article-title":"Iron, FRDA, and intermediary metabolism","volume":"137","author":"Pantopoulos","year":"2021","journal-title":"Blood"},{"key":"10.1016\/j.tem.2024.04.015_bb0510","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1146\/annurev-cancerbio-030518-055844","article-title":"The hallmarks of ferroptosis","volume":"3","author":"Dixon","year":"2019","journal-title":"Annu. Rev. Cancer Biol."},{"key":"10.1016\/j.tem.2024.04.015_bb0515","doi-asserted-by":"crossref","first-page":"802","DOI":"10.1016\/j.molcel.2023.12.008","article-title":"Dual regulation of SLC25A39 by AFG3L2 and iron controls mitochondrial glutathione homeostasis","volume":"84","author":"Shi","year":"2023","journal-title":"Mol. Cell"},{"key":"10.1016\/j.tem.2024.04.015_bb0520","doi-asserted-by":"crossref","first-page":"820","DOI":"10.1126\/science.adf4154","article-title":"Autoregulatory control of mitochondrial glutathione homeostasis","volume":"382","author":"Liu","year":"2023","journal-title":"Science"},{"key":"10.1016\/j.tem.2024.04.015_bb0525","doi-asserted-by":"crossref","first-page":"792","DOI":"10.1073\/pnas.86.3.792","article-title":"Expression of delta-aminolevulinate synthase in avian cells: separate genes encode erythroid-specific and nonspecific isozymes","volume":"86","author":"Riddle","year":"1989","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.tem.2024.04.015_bb0530","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1038\/84152","article-title":"The 2.0 A structure of human ferrochelatase, the terminal enzyme of heme biosynthesis","volume":"8","author":"Wu","year":"2001","journal-title":"Nat. Struct. Biol."},{"key":"10.1016\/j.tem.2024.04.015_bb0535","doi-asserted-by":"crossref","first-page":"4569","DOI":"10.1172\/JCI62422","article-title":"The mitochondrial heme exporter FLVCR1b mediates erythroid differentiation","volume":"122","author":"Chiabrando","year":"2012","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.tem.2024.04.015_bb0540","doi-asserted-by":"crossref","first-page":"855","DOI":"10.1515\/hsz-2020-0117","article-title":"From the discovery to molecular understanding of cellular iron-sulfur protein biogenesis","volume":"401","author":"Lill","year":"2020","journal-title":"Biol. Chem."},{"key":"10.1016\/j.tem.2024.04.015_bb0545","doi-asserted-by":"crossref","first-page":"398","DOI":"10.1016\/j.tig.2008.05.008","article-title":"Iron-sulfur cluster biogenesis and human disease","volume":"24","author":"Rouault","year":"2008","journal-title":"Trends Genet."},{"key":"10.1016\/j.tem.2024.04.015_bb0550","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1016\/j.molcel.2023.12.016","article-title":"METTL17 is an Fe-S cluster checkpoint for mitochondrial translation","volume":"84","author":"Ast","year":"2024","journal-title":"Mol. Cell"},{"key":"10.1016\/j.tem.2024.04.015_bb0555","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1083\/jcb.48.1.79","article-title":"The effects of iron deficiency on the hepatocyte: a biochemical and ultrastructural study","volume":"48","author":"Dallman","year":"1971","journal-title":"J. Cell Biol."},{"key":"10.1016\/j.tem.2024.04.015_bb0560","doi-asserted-by":"crossref","first-page":"973","DOI":"10.1136\/jcp.27.12.973","article-title":"Morphological abnormalities in lymphocyte mitochondria associated with iron-deficiency anaemia","volume":"27","author":"Jarvis","year":"1974","journal-title":"J. Clin. Pathol."},{"key":"10.1016\/j.tem.2024.04.015_bb0565","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1016\/0005-2728(94)90020-5","article-title":"Dietary iron deficiency in the rat. I. Abnormalities in energy metabolism of the hepatic tissue","volume":"1188","author":"Masini","year":"1994","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.tem.2024.04.015_bb0570","doi-asserted-by":"crossref","first-page":"2264","DOI":"10.1073\/pnas.261708798","article-title":"Iron deficiency and iron excess damage mitochondria and mitochondrial DNA in rats","volume":"99","author":"Walter","year":"2002","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.tem.2024.04.015_bb0575","doi-asserted-by":"crossref","first-page":"1868","DOI":"10.1152\/jappl.1989.67.5.1868","article-title":"(1989) Iron deficiency decreases gluconeogenesis in isolated rat hepatocytes","volume":"67","author":"Klempa","year":"1985","journal-title":"J. Appl. Physiol."},{"key":"10.1016\/j.tem.2024.04.015_bb0580","doi-asserted-by":"crossref","first-page":"1708","DOI":"10.4049\/jimmunol.1901399","article-title":"Cutting edge: activation-induced iron flux controls CD4 T cell proliferation by promoting proper IL-2R signaling and mitochondrial function","volume":"204","author":"Yarosz","year":"2020","journal-title":"J. Immunol."},{"key":"10.1016\/j.tem.2024.04.015_bb0585","doi-asserted-by":"crossref","DOI":"10.1126\/sciimmunol.abq0178","article-title":"Elevated transferrin receptor impairs T cell metabolism and function in systemic lupus erythematosus","volume":"8","author":"Voss","year":"2023","journal-title":"Sci. Immunol."},{"key":"10.1016\/j.tem.2024.04.015_bb0590","doi-asserted-by":"crossref","first-page":"8297","DOI":"10.1074\/jbc.RA118.001885","article-title":"Acute loss of iron-sulfur clusters results in metabolic reprogramming and generation of lipid droplets in mammalian cells","volume":"293","author":"Crooks","year":"2018","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.tem.2024.04.015_bb0595","doi-asserted-by":"crossref","first-page":"1036","DOI":"10.1002\/iub.2671","article-title":"Desaturases: structural and mechanistic insights into the biosynthesis of unsaturated fatty acids","volume":"74","author":"Cerone","year":"2022","journal-title":"IUBMB Life"},{"key":"10.1016\/j.tem.2024.04.015_bb0600","doi-asserted-by":"crossref","DOI":"10.1016\/j.bbcan.2020.188394","article-title":"Cholesterol metabolism: new functions and therapeutic approaches in cancer","volume":"1874","author":"Xu","year":"2020","journal-title":"Biochim. Biophys. Acta Rev. Cancer"},{"key":"10.1016\/j.tem.2024.04.015_bb0605","first-page":"2368","article-title":"Iron deficiency and supplementation in heart failure","volume":"8","author":"Lakhal-Littleton","year":"2024","journal-title":"Nat. Rev. Cardiol."},{"key":"10.1016\/j.tem.2024.04.015_bb0610","doi-asserted-by":"crossref","first-page":"2456","DOI":"10.1016\/j.drudis.2021.06.006","article-title":"Structural insights into understudied human cytochrome P450 enzymes","volume":"26","author":"Machalz","year":"2021","journal-title":"Drug Discov. Today"},{"key":"10.1016\/j.tem.2024.04.015_bb0615","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1210\/er.2010-0013","article-title":"The molecular biology, biochemistry, and physiology of human steroidogenesis and its disorders","volume":"32","author":"Miller","year":"2011","journal-title":"Endocr. Rev."},{"key":"10.1016\/j.tem.2024.04.015_bb0620","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1016\/0304-4165(86)90314-4","article-title":"Relationship between anemia and cholesterol metabolism in 'sex-linked anemic' (gene symbol, sla) mouse","volume":"883","author":"Au","year":"1986","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.tem.2024.04.015_bb0625","doi-asserted-by":"crossref","first-page":"2795","DOI":"10.21873\/anticanres.15060","article-title":"Association between iron and cholesterol in neuroblastomas","volume":"41","author":"Lee","year":"2021","journal-title":"Anticancer Res."},{"key":"10.1016\/j.tem.2024.04.015_bb0630","doi-asserted-by":"crossref","DOI":"10.1016\/j.jbc.2021.101156","article-title":"Iron loading induces cholesterol synthesis and sensitizes endothelial cells to TNF\u03b1-mediated apoptosis","volume":"297","author":"Fisher","year":"2021","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.tem.2024.04.015_bb0635","doi-asserted-by":"crossref","first-page":"3949","DOI":"10.1093\/eurheartj\/ehaa140","article-title":"The haemochromatosis gene Hfe and Kupffer cells control LDL cholesterol homeostasis and impact on atherosclerosis development","volume":"41","author":"Demetz","year":"2020","journal-title":"Eur. Heart J."},{"key":"10.1016\/j.tem.2024.04.015_bb0640","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1038\/s41435-021-00139-3","article-title":"Revisiting steroidogenesis and its role in immune regulation with the advanced tools and technologies","volume":"22","author":"Chakraborty","year":"2021","journal-title":"Genes Immun."},{"key":"10.1016\/j.tem.2024.04.015_bb0645","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1159\/000177633","article-title":"Reduced cortisol secretion in patients with iron deficiency","volume":"35","author":"Saad","year":"1991","journal-title":"Ann. Nutr. Metab."},{"key":"10.1016\/j.tem.2024.04.015_bb0650","doi-asserted-by":"crossref","first-page":"2062","DOI":"10.1172\/JCI29449","article-title":"Resurrection of vitamin D deficiency and rickets","volume":"116","author":"Holick","year":"2006","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.tem.2024.04.015_bb0655","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1038\/s41574-019-0312-5","article-title":"New aspects of vitamin D metabolism and action - addressing the skin as source and target","volume":"16","author":"Bikle","year":"2020","journal-title":"Nat. Rev. Endocrinol."},{"key":"10.1016\/j.tem.2024.04.015_bb0660","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1038\/s41581-019-0189-5","article-title":"FGF23 at the crossroads of phosphate, iron economy and erythropoiesis","volume":"16","author":"Edmonston","year":"2020","journal-title":"Nat. Rev. Nephrol."},{"key":"10.1016\/j.tem.2024.04.015_bb0665","doi-asserted-by":"crossref","first-page":"3598","DOI":"10.1093\/jn\/133.11.3598","article-title":"Dietary iron is associated with bone mineral density in healthy postmenopausal women","volume":"133","author":"Harris","year":"2003","journal-title":"J. Nutr."},{"key":"10.1016\/j.tem.2024.04.015_bb0670","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1186\/s12902-023-01389-0","article-title":"Dietary iron intake and its impact on osteopenia\/osteoporosis","volume":"23","author":"Liu","year":"2023","journal-title":"BMC Endocr. Disord."},{"key":"10.1016\/j.tem.2024.04.015_bb0675","doi-asserted-by":"crossref","first-page":"238","DOI":"10.3945\/jn.108.093757","article-title":"Severe iron deficiency decreases both bone formation and bone resorption in rats","volume":"139","author":"Katsumata","year":"2009","journal-title":"J. Nutr."},{"key":"10.1016\/j.tem.2024.04.015_bb0680","doi-asserted-by":"crossref","first-page":"3135","DOI":"10.1093\/jn\/131.10.3135","article-title":"Bone morphology, strength and density are compromised in iron-deficient rats and exacerbated by calcium restriction","volume":"132","author":"Medeiros","year":"2002","journal-title":"J. Nutr."},{"key":"10.1016\/j.tem.2024.04.015_bb0685","doi-asserted-by":"crossref","first-page":"948","DOI":"10.1124\/pr.113.008201","article-title":"Bile acid signaling in metabolic disease and drug therapy","volume":"66","author":"Li","year":"2014","journal-title":"Pharmacol. Rev."},{"key":"10.1016\/j.tem.2024.04.015_bb0690","doi-asserted-by":"crossref","first-page":"9780","DOI":"10.1038\/s41598-019-46150-7","article-title":"Iron overload reduces synthesis and elimination of bile acids in rat liver","volume":"9","author":"Prasnicka","year":"2019","journal-title":"Sci. Rep."},{"key":"10.1016\/j.tem.2024.04.015_bb0695","doi-asserted-by":"crossref","first-page":"354","DOI":"10.1016\/S0039-6060(97)90027-1","article-title":"Iron deficiency enhances cholesterol gallstone formation","volume":"122","author":"Johnston","year":"1997","journal-title":"Surgery"},{"key":"10.1016\/j.tem.2024.04.015_bb0700","doi-asserted-by":"crossref","first-page":"82","DOI":"10.3748\/wjg.v4.i1.82","article-title":"Bile acids in serum and bile of patients with cholesterol gallstone","volume":"4","author":"Han","year":"1998","journal-title":"World J. Gastroenterol."},{"key":"10.1016\/j.tem.2024.04.015_bb0705","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1007\/s00277-008-0557-x","article-title":"Patients with iron deficiency anemia have an increased prevalence of gallstones","volume":"88","author":"Pamuk","year":"2009","journal-title":"Ann. Hematol."},{"key":"10.1016\/j.tem.2024.04.015_bb0710","doi-asserted-by":"crossref","first-page":"771","DOI":"10.1038\/nrn3820","article-title":"Polyunsaturated fatty acids and their metabolites in brain function and disease","volume":"15","author":"Bazinet","year":"2014","journal-title":"Nat. Rev. Neurosci."},{"key":"10.1016\/j.tem.2024.04.015_bb0715","doi-asserted-by":"crossref","first-page":"1514","DOI":"10.1093\/jn\/117.9.1514","article-title":"Iron intake influences essential fatty acid and lipid composition of rat plasma and erythrocytes","volume":"117","author":"Cunnane","year":"1987","journal-title":"J. Nutr."},{"key":"10.1016\/j.tem.2024.04.015_bb0720","doi-asserted-by":"crossref","first-page":"573","DOI":"10.1007\/BF02534575","article-title":"Reduction of hepatic stearoyl-CoA desaturase activity in rats fed iron-deficient diets","volume":"18","author":"Rao","year":"1983","journal-title":"Lipids"},{"key":"10.1016\/j.tem.2024.04.015_bb0725","doi-asserted-by":"crossref","first-page":"889","DOI":"10.1007\/s11745-998-0285-8","article-title":"Different degrees of moderate iron deficiency modulate lipid metabolism of rats","volume":"33","author":"Stangl","year":"1998","journal-title":"Lipids"},{"key":"10.1016\/j.tem.2024.04.015_bb0730","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1038\/s41392-020-00443-w","article-title":"Metabolism pathways of arachidonic acids: mechanisms and potential therapeutic targets","volume":"6","author":"Wang","year":"2021","journal-title":"Signal Transduct. Target. Ther."},{"key":"10.1016\/j.tem.2024.04.015_bb0735","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1186\/gb-2004-5-9-241","article-title":"The cyclooxygenases","volume":"5","author":"Chandrasekharan","year":"2004","journal-title":"Genome Biol."},{"key":"10.1016\/j.tem.2024.04.015_bb0740","doi-asserted-by":"crossref","first-page":"2395","DOI":"10.1161\/01.CIR.103.19.2395","article-title":"Increased release of arachidonic acid and eicosanoids in iron-overloaded cardiomyocytes","volume":"103","author":"Mattera","year":"2001","journal-title":"Circulation"},{"key":"10.1016\/j.tem.2024.04.015_bb0745","doi-asserted-by":"crossref","first-page":"2002","DOI":"10.1002\/2211-5463.12534","article-title":"Human nitrobindin: the first example of an all-\u03b2-barrel ferric heme-protein that catalyzes peroxynitrite detoxification","volume":"8","author":"De Simone","year":"2018","journal-title":"FEBS Open Bio."},{"key":"10.1016\/j.tem.2024.04.015_bb0750","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1006\/jmbi.1999.3458","article-title":"Active and inhibited human catalase structures: ligand and NADPH binding and catalytic mechanism","volume":"296","author":"Putnam","year":"2000","journal-title":"J. Mol. Biol."},{"key":"10.1016\/j.tem.2024.04.015_bb0755","doi-asserted-by":"crossref","first-page":"41101","DOI":"10.1074\/jbc.M507528200","article-title":"Structure of human phytanoyl-CoA 2-hydroxylase identifies molecular mechanisms of Refsum disease","volume":"280","author":"McDonough","year":"2005","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.tem.2024.04.015_bb0760","series-title":"Nutrient Metabolism","first-page":"265","article-title":"Amino acids and nitrogen compounds","author":"Kohlmeier","year":"2015"},{"key":"10.1016\/j.tem.2024.04.015_bb0765","doi-asserted-by":"crossref","first-page":"1371","DOI":"10.1038\/s12276-023-01028-7","article-title":"Immune regulation through tryptophan metabolism","volume":"55","author":"Seo","year":"2023","journal-title":"Exp. Mol. Med."},{"key":"10.1016\/j.tem.2024.04.015_bb0770","doi-asserted-by":"crossref","first-page":"14548","DOI":"10.1038\/s41598-019-51215-8","article-title":"Associations between tryptophan and iron metabolism observed in individuals with and without iron deficiency","volume":"9","author":"Wenninger","year":"2019","journal-title":"Sci. Rep."},{"key":"10.1016\/j.tem.2024.04.015_bb0775","doi-asserted-by":"crossref","first-page":"13165","DOI":"10.1074\/jbc.R113.455311","article-title":"The molybdenum cofactor","volume":"288","author":"Mendel","year":"2013","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.tem.2024.04.015_bb0780","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1016\/j.cbpa.2016.03.016","article-title":"Molybdenum cofactor and human disease","volume":"31","author":"Schwarz","year":"2016","journal-title":"Curr. Opin. Chem. Biol."},{"key":"10.1016\/j.tem.2024.04.015_bb0785","doi-asserted-by":"crossref","first-page":"748","DOI":"10.1002\/jimd.12216","article-title":"Oxygen and nitrite reduction by heme-deficient sulphite oxidase in a patient with mild sulphite oxidase deficiency","volume":"43","author":"Bender","year":"2020","journal-title":"J. Inherit. Metab. Dis."},{"key":"10.1016\/j.tem.2024.04.015_bb0790","doi-asserted-by":"crossref","first-page":"1652","DOI":"10.1093\/jn\/114.9.1652","article-title":"Effect of molybdenum-deficient and low iron diets on xanthine oxidase activity and iron status in rats","volume":"114","author":"Kelley","year":"1984","journal-title":"J. Nutr."},{"key":"10.1016\/j.tem.2024.04.015_bb0795","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1016\/0305-0491(94)00109-8","article-title":"Effect of long term iron deficiency on the activities of hepatic and extra-hepatic drug metabolising enzymes in Fischer rats","volume":"110","author":"Rao","year":"1995","journal-title":"Comp. Biochem. Physiol. B Biochem. Mol. Biol."},{"key":"10.1016\/j.tem.2024.04.015_bb0800","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1038\/ng.3465","article-title":"A missense mutation in TFRC, encoding transferrin receptor 1, causes combined immunodeficiency","volume":"48","author":"Jabara","year":"2016","journal-title":"Nat. Genet."},{"key":"10.1016\/j.tem.2024.04.015_bb0805","doi-asserted-by":"crossref","first-page":"1103","DOI":"10.1007\/s10875-020-00851-1","article-title":"Clinical and immunological characterization of combined immunodeficiency due to TFRC mutation in eight patients","volume":"40","author":"Aljohani","year":"2020","journal-title":"J. Clin. Immunol."},{"key":"10.1016\/j.tem.2024.04.015_bb0810","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1007\/s10875-024-01658-0","article-title":"A novel homozygous germline mutation in transferrin receptor 1 (TfR1) leads to combined immunodeficiency and provides new insights into iron-immunity axis","volume":"44","author":"Aba","year":"2024","journal-title":"J. Clin. Immunol."},{"key":"10.1016\/j.tem.2024.04.015_bb0815","doi-asserted-by":"crossref","first-page":"M59","DOI":"10.1093\/gerona\/54.2.M59","article-title":"Relationship between the response to influenza vaccination and the nutritional status in institutionalized elderly subjects","volume":"54","author":"F\u00fcl\u00f6p","year":"1999","journal-title":"J. Gerontol. A Biol. Sci. Med. Sci."},{"key":"10.1016\/j.tem.2024.04.015_bb0820","doi-asserted-by":"crossref","first-page":"e666","DOI":"10.1016\/S2352-3026(21)00201-5","article-title":"Vaccine efficacy and iron deficiency: an intertwined pair?","volume":"8","author":"Drakesmith","year":"2021","journal-title":"Lancet Haematol."},{"key":"10.1016\/j.tem.2024.04.015_bb0825","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2022.816282","article-title":"Iron metabolism and immune regulation","volume":"13","author":"Ni","year":"2022","journal-title":"Front. Immunol."},{"key":"10.1016\/j.tem.2024.04.015_bb0830","doi-asserted-by":"crossref","first-page":"492","DOI":"10.1016\/j.immuni.2016.02.016","article-title":"Macrophages and iron metabolism","volume":"44","author":"Soares","year":"2016","journal-title":"Immunity"},{"key":"10.1016\/j.tem.2024.04.015_bb0835","doi-asserted-by":"crossref","first-page":"116","DOI":"10.3389\/fmolb.2019.00116","article-title":"The role of iron regulation in immunometabolism and immune-related disease","volume":"6","author":"Cronin","year":"2019","journal-title":"Front. Mol. Biosci."},{"key":"10.1016\/j.tem.2024.04.015_bb0840","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1179\/135100003225002664","article-title":"Redox properties of myeloperoxidase","volume":"8","author":"Arnhold","year":"2003","journal-title":"Redox Rep."},{"key":"10.1016\/j.tem.2024.04.015_bb0845","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1084\/jem.192.2.227","article-title":"Antimicrobial actions of the NADPH phagocyte oxidase and inducible nitric oxide synthase in experimental salmonellosis. I. Effects on microbial killing by activated peritoneal macrophages in vitro","volume":"192","author":"Vazquez-Torres","year":"2000","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.tem.2024.04.015_bb0850","doi-asserted-by":"crossref","DOI":"10.1126\/sciadv.abq5384","article-title":"Plasma iron controls neutrophil production and function","volume":"8","author":"Frost","year":"2022","journal-title":"Sci. Adv."},{"key":"10.1016\/j.tem.2024.04.015_bb0855","doi-asserted-by":"crossref","DOI":"10.1126\/sciadv.abq4469","article-title":"Iron regulatory protein (IRP)-mediated iron homeostasis is critical for neutrophil development and differentiation in the bone marrow","volume":"8","author":"Bonadonna","year":"2022","journal-title":"Sci. Adv."},{"key":"10.1016\/j.tem.2024.04.015_bb0860","doi-asserted-by":"crossref","first-page":"824","DOI":"10.1002\/eji.200939889","article-title":"Differential regulation of iron homeostasis during human macrophage polarized activation","volume":"40","author":"Recalcati","year":"2010","journal-title":"Eur. J. Immunol."},{"key":"10.1016\/j.tem.2024.04.015_bb0865","doi-asserted-by":"crossref","first-page":"985","DOI":"10.1172\/JCI44490","article-title":"An unrestrained proinflammatory M1 macrophage population induced by iron impairs wound healing in humans and mice","volume":"121","author":"Sindrilaru","year":"2011","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.tem.2024.04.015_bb0870","doi-asserted-by":"crossref","first-page":"498","DOI":"10.1016\/j.celrep.2019.06.039","article-title":"Acute iron deprivation reprograms human macrophage metabolism and reduces inflammation in vivo","volume":"28","author":"Pereira","year":"2019","journal-title":"Cell Rep."},{"key":"10.1016\/j.tem.2024.04.015_bb0875","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1084\/jem.191.1.129","article-title":"Recruitment and activation of natural killer (NK) cells in vivo determined by the target cell phenotype. An adaptive component of NK cell-mediated responses","volume":"191","author":"Glas","year":"2000","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.tem.2024.04.015_bb0880","doi-asserted-by":"crossref","first-page":"5376","DOI":"10.1038\/s41467-021-25715-z","article-title":"Metabolic requirements of NK cells during the acute response against retroviral infection","volume":"12","author":"Littwitz-Salomon","year":"2021","journal-title":"Nat. Commun."},{"key":"10.1016\/j.tem.2024.04.015_bb0885","doi-asserted-by":"crossref","first-page":"S3","DOI":"10.1016\/j.jaci.2009.12.980","article-title":"Overview of the immune response","volume":"125","author":"Chaplin","year":"2010","journal-title":"J. Allergy Clin. Immunol."},{"key":"10.1016\/j.tem.2024.04.015_bb0890","doi-asserted-by":"crossref","first-page":"195","DOI":"10.3389\/fimmu.2020.00195","article-title":"The role of calcium-calcineurin-NFAT signaling pathway in health and autoimmune diseases","volume":"11","author":"Park","year":"2020","journal-title":"Front. Immunol."},{"key":"10.1016\/j.tem.2024.04.015_bb0895","doi-asserted-by":"crossref","first-page":"21296","DOI":"10.1074\/jbc.272.34.21296","article-title":"Kinetic and spectroscopic analyses of mutants of a conserved histidine in the metallophosphatases calcineurin and lambda protein phosphatase","volume":"272","author":"Mertz","year":"1997","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.tem.2024.04.015_bb0900","doi-asserted-by":"crossref","first-page":"1057","DOI":"10.1002\/JLB.3MA0821-015R","article-title":"Iron deprivation restrains the differentiation and pathogenicity of T helper 17 cell","volume":"110","author":"Li","year":"2021","journal-title":"J. Leukoc. Biol."},{"key":"10.1016\/j.tem.2024.04.015_bb0905","doi-asserted-by":"crossref","DOI":"10.1002\/ctm2.999","article-title":"Iron controls T helper cell pathogenicity by promoting glucose metabolism in autoimmune myopathy","volume":"12","author":"Lai","year":"2022","journal-title":"Clin. Transl. Med."},{"key":"10.1016\/j.tem.2024.04.015_bb0910","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1016\/j.immuni.2018.05.008","article-title":"Iron drives T helper cell pathogenicity by promoting RNA-binding protein PCBP1-mediated proinflammatory cytokine production","volume":"49","author":"Wang","year":"2018","journal-title":"Immunity"},{"key":"10.1016\/j.tem.2024.04.015_bb0915","doi-asserted-by":"crossref","first-page":"1310","DOI":"10.1111\/apa.14287","article-title":"Nutritional influences on brain development","volume":"107","author":"Georgieff","year":"2018","journal-title":"Acta Paediatr."},{"key":"10.1016\/j.tem.2024.04.015_bb0920","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1002\/jha2.321","article-title":"Iron, neuro-bioavailability and depression","volume":"3","author":"Berthou","year":"2022","journal-title":"EJHaem"},{"key":"10.1016\/j.tem.2024.04.015_bb0925","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1038\/s41572-021-00311-z","article-title":"Restless legs syndrome","volume":"7","author":"Manconi","year":"2021","journal-title":"Nat. Rev. Dis. Primers"},{"key":"10.1016\/j.tem.2024.04.015_bb0930","doi-asserted-by":"crossref","first-page":"R276","DOI":"10.1152\/ajpregu.00429.2014","article-title":"Fetal iron deficiency induces chromatin remodeling at the Bdnf locus in adult rat hippocampus","volume":"308","author":"Tran","year":"2015","journal-title":"Am. J. Physiol. Regul. Integr. Comp. Physiol."},{"key":"10.1016\/j.tem.2024.04.015_bb0935","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1002\/(SICI)1098-1136(199606)17:2<83::AID-GLIA1>3.0.CO;2-7","article-title":"Relationship of iron to oligodendrocytes and myelination","volume":"17","author":"Connor","year":"1996","journal-title":"Glia"},{"key":"10.1016\/j.tem.2024.04.015_bb0940","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1002\/ijgo.14951","article-title":"The importance of iron deficiency in pregnancy on fetal, neonatal, and infant neurodevelopmental outcomes","volume":"162","author":"Georgieff","year":"2023","journal-title":"Int. J. Gynaecol. Obstet."},{"key":"10.1016\/j.tem.2024.04.015_bb0945","doi-asserted-by":"crossref","first-page":"597","DOI":"10.1089\/thy.2016.0635","article-title":"Multiple nutritional factors and the risk of Hashimoto's thyroiditis","volume":"27","author":"Hu","year":"2017","journal-title":"Thyroid"},{"key":"10.1016\/j.tem.2024.04.015_bb0950","doi-asserted-by":"crossref","first-page":"418","DOI":"10.1016\/j.molmed.2013.04.004","article-title":"Energy balance regulation by thyroid hormones at central level","volume":"19","author":"L\u00f3pez","year":"2013","journal-title":"Trends Mol. Med."},{"key":"10.1016\/j.tem.2024.04.015_bb0955","doi-asserted-by":"crossref","first-page":"1951","DOI":"10.1093\/jn\/132.7.1951","article-title":"Iron deficiency anemia reduces thyroid peroxidase activity in rats","volume":"132","author":"Hess","year":"2002","journal-title":"J. Nutr."},{"key":"10.1016\/j.tem.2024.04.015_bb0960","doi-asserted-by":"crossref","first-page":"691","DOI":"10.1016\/0024-3205(82)90285-5","article-title":"Interactions of iron deficiency, anemia, and thyroid hormone levels in response of rats to cold exposure","volume":"30","author":"Beard","year":"1982","journal-title":"Life Sci."},{"key":"10.1016\/j.tem.2024.04.015_bb0965","doi-asserted-by":"crossref","first-page":"813","DOI":"10.1093\/ajcn\/52.5.813","article-title":"Impaired thermoregulation and thyroid function in iron-deficiency anemia","volume":"52","author":"Beard","year":"1990","journal-title":"Am. J. Clin. Nutr."},{"key":"10.1016\/j.tem.2024.04.015_bb0970","first-page":"R380","article-title":"Effect of exposure to low temperature on normal and iron-deficient subjects","volume":"246","author":"Martinez-Torres","year":"1984","journal-title":"Am. J. Phys."},{"key":"10.1016\/j.tem.2024.04.015_bb0975","doi-asserted-by":"crossref","DOI":"10.1101\/cshperspect.a004978","article-title":"The collagen family","volume":"3","author":"Ricard-Blum","year":"2011","journal-title":"Cold Spring Harb. Perspect. Biol."},{"key":"10.1016\/j.tem.2024.04.015_bb0980","doi-asserted-by":"crossref","first-page":"6891","DOI":"10.3390\/ijms24086891","article-title":"Iron deficiency and iron deficiency anemia: potential risk factors in bone loss","volume":"24","author":"Yang","year":"2023","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.tem.2024.04.015_bb0985","article-title":"Carotenoid metabolism at the intestinal barrier","volume":"1865","author":"von Lintig","year":"2020","journal-title":"Biochim. Biophys. Acta Mol. Cell Biol. Lipids"},{"key":"10.1016\/j.tem.2024.04.015_bb0990","doi-asserted-by":"crossref","DOI":"10.1016\/j.pharmthera.2019.107400","article-title":"Biochemical and physiological importance of the CYP26 retinoic acid hydroxylases","volume":"204","author":"Isoherranen","year":"2019","journal-title":"Pharmacol. Ther."},{"key":"10.1016\/j.tem.2024.04.015_bb0995","doi-asserted-by":"crossref","first-page":"1291","DOI":"10.1093\/jn\/130.5.1291","article-title":"Kinetic analysis shows that iron deficiency decreases liver vitamin A mobilization in rats","volume":"130","author":"Jang","year":"2000","journal-title":"J. Nutr."},{"key":"10.1016\/j.tem.2024.04.015_bb1000","doi-asserted-by":"crossref","first-page":"1982","DOI":"10.1093\/jn\/nxaa098","article-title":"Dietary iron repletion stimulates hepatic mobilization of vitamin A in previously iron-deficient rats as determined by model-based compartmental analysis","volume":"150","author":"Li","year":"2020","journal-title":"J. Nutr."},{"key":"10.1016\/j.tem.2024.04.015_bb1005","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1016\/j.jcf.2004.04.003","article-title":"Vitamin A levels in patients with CF are influenced by the inflammatory response","volume":"3","author":"Greer","year":"2004","journal-title":"J. Cyst. Fibros."},{"key":"10.1016\/j.tem.2024.04.015_bb1010","doi-asserted-by":"crossref","first-page":"2835","DOI":"10.1074\/jbc.M508903200","article-title":"RPE65 is an iron(II)-dependent isomerohydrolase in the retinoid visual cycle","volume":"281","author":"Moiseyev","year":"2006","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.tem.2024.04.015_bb1015","doi-asserted-by":"crossref","first-page":"29217","DOI":"10.1074\/jbc.M500409200","article-title":"Key role of conserved histidines in recombinant mouse beta-carotene 15,15'-monooxygenase-1 activity","volume":"280","author":"Poliakov","year":"2005","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.tem.2024.04.015_bb1020","doi-asserted-by":"crossref","DOI":"10.15252\/emmm.202216525","article-title":"HIF2\u03b1 activation and mitochondrial deficit due to iron chelation cause retinal atrophy","volume":"15","author":"Kong","year":"2023","journal-title":"EMBO Mol. Med."},{"key":"10.1016\/j.tem.2024.04.015_bb1025","doi-asserted-by":"crossref","DOI":"10.7554\/eLife.19804","article-title":"An essential cell-autonomous role for hepcidin in cardiac iron homeostasis","volume":"5","author":"Lakhal-Littleton","year":"2016","journal-title":"Elife"},{"key":"10.1016\/j.tem.2024.04.015_bb1030","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1016\/j.celrep.2015.09.023","article-title":"Lethal cardiomyopathy in mice lacking transferrin receptor in the heart","volume":"13","author":"Xu","year":"2015","journal-title":"Cell Rep."},{"key":"10.1016\/j.tem.2024.04.015_bb1035","doi-asserted-by":"crossref","first-page":"3447","DOI":"10.1038\/s41467-021-23660-5","article-title":"Maternal iron deficiency perturbs embryonic cardiovascular development in mice","volume":"12","author":"Kalisch-Smith","year":"2021","journal-title":"Nat. Commun."},{"key":"10.1016\/j.tem.2024.04.015_bb1040","doi-asserted-by":"crossref","first-page":"2169","DOI":"10.1093\/ajcn\/34.10.2169","article-title":"Influence of dietary iron deficiency on hemoglobin, myoglobin, their respective reductases, and skeletal muscle mitochondrial respiration","volume":"34","author":"Hagler","year":"1981","journal-title":"Am. J. Clin. Nutr."},{"key":"10.1016\/j.tem.2024.04.015_bb1045","doi-asserted-by":"crossref","DOI":"10.1161\/JAHA.121.022853","article-title":"Myocardial iron deficiency and mitochondrial dysfunction in advanced heart failure in humans","volume":"11","author":"Zhang","year":"2022","journal-title":"J. Am. Heart Assoc."},{"key":"10.1016\/j.tem.2024.04.015_bb1050","article-title":"Iron-deficiency anemia results in transcriptional and metabolic remodeling in the heart toward a glycolytic phenotype","volume":"7","author":"Chung","year":"2020","journal-title":"Front. Cardiovasc. Med."},{"key":"10.1016\/j.tem.2024.04.015_bb1055","doi-asserted-by":"crossref","first-page":"13827","DOI":"10.1016\/S0021-9258(18)67094-2","article-title":"Perturbation of mitochondrial composition in muscle by iron deficiency. Implications regarding regulation of mitochondrial assembly","volume":"261","author":"Cartier","year":"1986","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.tem.2024.04.015_bb1060","doi-asserted-by":"crossref","first-page":"1271","DOI":"10.1172\/JCI200420945","article-title":"IL-6 mediates hypoferremia of inflammation by inducing the synthesis of the iron regulatory hormone hepcidin","volume":"113","author":"Nemeth","year":"2004","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.tem.2024.04.015_bb1065","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1007\/s00281-015-0534-0","article-title":"Immunometabolism within the tuberculosis granuloma: amino acids, hypoxia, and cellular respiration","volume":"38","author":"Qualls","year":"2016","journal-title":"Semin. Immunopathol."},{"key":"10.1016\/j.tem.2024.04.015_bb1070","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1182\/blood-2009-10-251496","article-title":"Iron control of erythroid development by a novel aconitase-associated regulatory pathway","volume":"116","author":"Bullock","year":"2010","journal-title":"Blood"},{"key":"10.1016\/j.tem.2024.04.015_bb1075","doi-asserted-by":"crossref","first-page":"320","DOI":"10.1186\/s13054-020-03051-w","article-title":"Systemic hypoferremia and severity of hypoxemic respiratory failure in COVID-19","volume":"24","author":"Shah","year":"2020","journal-title":"Crit. Care"},{"key":"10.1016\/j.tem.2024.04.015_bb1080","doi-asserted-by":"crossref","DOI":"10.1097\/HS9.0000000000000492","article-title":"Hypoferremia is associated with increased hospitalization and oxygen demand in COVID-19 patients","volume":"4","author":"Hippchen","year":"2020","journal-title":"Hemasphere"},{"key":"10.1016\/j.tem.2024.04.015_bb1085","doi-asserted-by":"crossref","first-page":"546","DOI":"10.3390\/metabo12060546","article-title":"The impact of iron dyshomeostasis and anaemia on long-term pulmonary recovery and persisting symptom burden after COVID-19: a prospective observational cohort study","volume":"12","author":"Sonnweber","year":"2022","journal-title":"Metabolites"},{"key":"10.1016\/j.tem.2024.04.015_bb1090","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1038\/s41590-024-01754-8","article-title":"Iron dysregulation and inflammatory stress erythropoiesis associates with long-term outcome of COVID-19","volume":"25","author":"Hanson","year":"2024","journal-title":"Nat. Immunol."},{"key":"10.1016\/j.tem.2024.04.015_bb1095","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1038\/s41590-024-01759-3","article-title":"Alterations of iron homeostasis as a potential druggable driver of long COVID","volume":"25","author":"Marques","year":"2024","journal-title":"Nat. Immunol."},{"key":"10.1016\/j.tem.2024.04.015_bb1100","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1039\/b511249b","article-title":"Hypoxia-inducible factor prolyl hydroxylase 2 has a high affinity for ferrous iron and 2-oxoglutarate","volume":"1","author":"McNeill","year":"2005","journal-title":"Mol. BioSyst."},{"key":"10.1016\/j.tem.2024.04.015_bb1105","doi-asserted-by":"crossref","first-page":"118","DOI":"10.4161\/cib.13844","article-title":"Genome-wide comprehensive analysis of human helicases","volume":"4","author":"Umate","year":"2011","journal-title":"Commun. Integr. Biol."},{"key":"10.1016\/j.tem.2024.04.015_bb1110","doi-asserted-by":"crossref","first-page":"723","DOI":"10.1056\/NEJMoa2308809","article-title":"Rusfertide, a hepcidin mimetic, for control of erythrocytosis in polycythemia vera","volume":"390","author":"Kremyanskaya","year":"2024","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.tem.2024.04.015_bb1115","doi-asserted-by":"crossref","first-page":"1811","DOI":"10.1016\/S0140-6736(23)00287-8","article-title":"Haemochromatosis","volume":"401","author":"Adams","year":"2023","journal-title":"Lancet"},{"key":"10.1016\/j.tem.2024.04.015_bb1120","doi-asserted-by":"crossref","first-page":"1604","DOI":"10.1021\/acschembio.5b00245","article-title":"Human haploid cell genetics reveals roles for lipid metabolism genes in nonapoptotic cell death","volume":"10","author":"Dixon","year":"2015","journal-title":"ACS Chem. Biol."},{"key":"10.1016\/j.tem.2024.04.015_bb1125","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1038\/nchembio.2239","article-title":"ACSL4 dictates ferroptosis sensitivity by shaping cellular lipid composition","volume":"13","author":"Doll","year":"2017","journal-title":"Nat. Chem. Biol."},{"key":"10.1016\/j.tem.2024.04.015_bb1130","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1038\/nchembio.2238","article-title":"Oxidized arachidonic and adrenic PEs navigate cells to ferroptosis","volume":"13","author":"Kagan","year":"2017","journal-title":"Nat. Chem. Biol."},{"key":"10.1016\/j.tem.2024.04.015_bb1135","doi-asserted-by":"crossref","first-page":"1338","DOI":"10.1016\/j.bbrc.2016.08.124","article-title":"Identification of ACSL4 as a biomarker and contributor of ferroptosis","volume":"478","author":"Yuan","year":"2016","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.tem.2024.04.015_bb1140","doi-asserted-by":"crossref","DOI":"10.1038\/s41580-024-00703-5","article-title":"The cell biology of ferroptosis","author":"Dixon","year":"2024","journal-title":"Nat. Rev. Mol. Cell Biol."}],"container-title":["Trends in Endocrinology &amp; Metabolism"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1043276024001097?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1043276024001097?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,12,2]],"date-time":"2024-12-02T11:13:27Z","timestamp":1733138007000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1043276024001097"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,12]]},"references-count":228,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2024,12]]}},"alternative-id":["S1043276024001097"],"URL":"https:\/\/doi.org\/10.1016\/j.tem.2024.04.015","relation":{},"ISSN":["1043-2760"],"issn-type":[{"value":"1043-2760","type":"print"}],"subject":[],"published":{"date-parts":[[2024,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Why cells need iron: a compendium of iron utilisation","name":"articletitle","label":"Article Title"},{"value":"Trends in Endocrinology & Metabolism","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.tem.2024.04.015","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 The Authors. Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}]}}