{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,20]],"date-time":"2026-09-20T16:45:16Z","timestamp":1789922716402,"version":"4.0.1"},"reference-count":59,"publisher":"Elsevier BV","issue":"12","license":[{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,12,2]],"date-time":"2025-12-02T00:00:00Z","timestamp":1764633600000},"content-version":"am","delay-in-days":366,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100009633","name":"Eunice Kennedy Shriver National Institute of Child Health and Human Development","doi-asserted-by":"publisher","award":["R01 HD090066"],"award-info":[{"award-number":["R01 HD090066"]}],"id":[{"id":"10.13039\/100009633","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100009633","name":"Eunice Kennedy Shriver National Institute of Child Health and Human Development","doi-asserted-by":"publisher","award":["R21 HD109726"],"award-info":[{"award-number":["R21 HD109726"]}],"id":[{"id":"10.13039\/100009633","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.fr","clinicalkey.jp","clinicalkey.es","clinicalkey.com.au","clinicalkey.com","bmn.com","cell.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Trends in Endocrinology &amp; Metabolism"],"published-print":{"date-parts":[[2024,12]]},"DOI":"10.1016\/j.tem.2024.07.006","type":"journal-article","created":{"date-parts":[[2024,7,29]],"date-time":"2024-07-29T08:17:39Z","timestamp":1722241059000},"page":"1091-1099","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":19,"title":["Maternal\u2013fetal mechanisms underlying adaptation to hypoxia during early pregnancy"],"prefix":"10.1016","volume":"35","author":[{"given":"Indrani C.","family":"Bagchi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Milan K.","family":"Bagchi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.tem.2024.07.006_bb0005","doi-asserted-by":"crossref","first-page":"1508","DOI":"10.1126\/science.7985020","article-title":"Implantation and the placenta: key pieces of the development puzzle","volume":"266","author":"Cross","year":"1994","journal-title":"Science"},{"key":"10.1016\/j.tem.2024.07.006_bb0010","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1006\/dbio.2000.9767","article-title":"Embryo implantation","volume":"223","author":"Carson","year":"2000","journal-title":"Dev. Biol."},{"key":"10.1016\/j.tem.2024.07.006_bb0015","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1055\/s-0029-1242989","article-title":"Endometrial decidualization: of mice and men","volume":"28","author":"Ramathal","year":"2010","journal-title":"Semin. Reprod. Med."},{"key":"10.1016\/j.tem.2024.07.006_bb0020","doi-asserted-by":"crossref","first-page":"1408","DOI":"10.1210\/me.2014-1074","article-title":"Minireview: steroid-regulated paracrine mechanisms controlling implantation","volume":"28","author":"Pawar","year":"2014","journal-title":"Mol. Endocrinol."},{"key":"10.1016\/j.tem.2024.07.006_bb0025","doi-asserted-by":"crossref","first-page":"939","DOI":"10.1016\/j.mam.2012.12.011","article-title":"Physiological and molecular determinants of embryo implantation","volume":"34","author":"Zhang","year":"2013","journal-title":"Mol. Asp. Med."},{"key":"10.1016\/j.tem.2024.07.006_bb0030","doi-asserted-by":"crossref","first-page":"724","DOI":"10.1016\/j.semcdb.2013.08.004","article-title":"Role of nuclear receptors in blastocyst implantation","volume":"24","author":"Vasquez","year":"2013","journal-title":"Semin. Cell Dev. Biol."},{"key":"10.1016\/j.tem.2024.07.006_bb0035","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1055\/s-2007-991042","article-title":"Decidualization of the human endometrium: mechanisms, functions, and clinical perspectives","volume":"25","author":"Gellersen","year":"2007","journal-title":"Semin. Reprod. Med."},{"key":"10.1016\/j.tem.2024.07.006_bb0040","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1016\/S1043-2760(01)00379-4","article-title":"Regulation of angiogenesis in the endometrium","volume":"12","author":"Smith","year":"2001","journal-title":"Trends Endocrinol. Metab."},{"key":"10.1016\/j.tem.2024.07.006_bb0045","doi-asserted-by":"crossref","first-page":"336","DOI":"10.1177\/1933719108317975","article-title":"Review article: steroid hormones and uterine vascular adaptation to pregnancy","volume":"15","author":"Chang","year":"2008","journal-title":"Reprod. Sci."},{"key":"10.1016\/j.tem.2024.07.006_bb0050","doi-asserted-by":"crossref","first-page":"744","DOI":"10.1172\/JCI200422991","article-title":"Trophoblast differentiation during embryo implantation and formation of the maternal\u2013fetal interface","volume":"114","author":"Red-Horse","year":"2004","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.tem.2024.07.006_bb0055","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1016\/S1521-6934(02)00130-X","article-title":"The endometrium as a cause of implantation failure","volume":"17","author":"Sharkey","year":"2003","journal-title":"Best Pract. Res. Clin. Obstet. Gynaecol."},{"key":"10.1016\/j.tem.2024.07.006_bb0060","doi-asserted-by":"crossref","first-page":"352","DOI":"10.1038\/s41467-017-00308-x","article-title":"Decidualisation and placentation defects are a major cause of age-related reproductive decline","volume":"8","author":"Woods","year":"2017","journal-title":"Nat. Commun."},{"key":"10.1016\/j.tem.2024.07.006_bb0065","doi-asserted-by":"crossref","first-page":"E8468","DOI":"10.1073\/pnas.1706546114","article-title":"Defective decidualization during and after severe preeclampsia reveals a possible maternal contribution to the etiology","volume":"114","author":"Garrido-Gomez","year":"2017","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.tem.2024.07.006_bb0070","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1016\/j.placenta.2017.06.005","article-title":"Emerging role for dysregulated decidualization in the genesis of preeclampsia","volume":"60","author":"Conrad","year":"2017","journal-title":"Placenta"},{"key":"10.1016\/j.tem.2024.07.006_bb0075","doi-asserted-by":"crossref","first-page":"9675","DOI":"10.3390\/ijms22189675","article-title":"The impact of hypoxia in early pregnancy on placental cells","volume":"22","author":"Zhao","year":"2021","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.tem.2024.07.006_bb0080","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/j.semcdb.2022.03.041","article-title":"Glucose and oxygen in the early intrauterine environment and their role in developmental abnormalities","volume":"131","author":"Hufnagel","year":"2022","journal-title":"Semin. Cell Dev. Biol."},{"key":"10.1016\/j.tem.2024.07.006_bb0085","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1093\/humupd\/dmp046","article-title":"Beyond oxygen: complex regulation and activity of hypoxia inducible factors in pregnancy","volume":"16","author":"Pringle","year":"2010","journal-title":"Hum. Reprod. Update"},{"key":"10.1016\/j.tem.2024.07.006_bb0090","doi-asserted-by":"crossref","first-page":"3186","DOI":"10.1172\/JCI98931","article-title":"HIF2alpha in the uterine stroma permits embryo invasion and luminal epithelium detachment","volume":"128","author":"Matsumoto","year":"2018","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.tem.2024.07.006_bb0095","doi-asserted-by":"crossref","first-page":"14532","DOI":"10.1073\/pnas.2000810117","article-title":"A hypoxia-induced Rab pathway regulates embryo implantation by controlled trafficking of secretory granules","volume":"117","author":"Bhurke","year":"2020","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.tem.2024.07.006_bb0100","doi-asserted-by":"crossref","first-page":"4826","DOI":"10.1038\/s41467-023-40424-5","article-title":"Extravillous trophoblast cell lineage development is associated with active remodeling of the chromatin landscape","volume":"14","author":"Varberg","year":"2023","journal-title":"Nat. Commun."},{"key":"10.1016\/j.tem.2024.07.006_bb0105","doi-asserted-by":"crossref","DOI":"10.1073\/pnas.2200252119","article-title":"Extracellular vesicles secreted by human uterine stromal cells regulate decidualization, angiogenesis, and trophoblast differentiation","volume":"119","author":"Ma","year":"2022","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.tem.2024.07.006_bb0110","doi-asserted-by":"crossref","DOI":"10.1210\/endocr\/bqac165","article-title":"Extracellular vesicles secreted by mouse decidual cells carry critical information for the establishment of pregnancy","volume":"163","author":"Ma","year":"2022","journal-title":"Endocrinology"},{"key":"10.1016\/j.tem.2024.07.006_bb0115","doi-asserted-by":"crossref","first-page":"2584","DOI":"10.3390\/cells12222584","article-title":"Role of endometrial extracellular vesicles in mediating cell-to-cell communication in the uterus: a review","volume":"12","author":"Beal","year":"2023","journal-title":"Cells"},{"key":"10.1016\/j.tem.2024.07.006_bb0120","doi-asserted-by":"crossref","first-page":"380","DOI":"10.1016\/S1472-6483(10)61443-5","article-title":"Observations on intrauterine oxygen tension measured by fibre-optic microsensors","volume":"13","author":"Ottosen","year":"2006","journal-title":"Reprod. Biomed. Online"},{"key":"10.1016\/j.tem.2024.07.006_bb0125","doi-asserted-by":"crossref","first-page":"304","DOI":"10.1016\/S0015-0282(16)41722-X","article-title":"The temperature, pH, and partial pressure of oxygen in the cervix and uterus of women and uterus of rats during the cycle","volume":"27","author":"Yedwab","year":"1976","journal-title":"Fertil. Steril."},{"key":"10.1016\/j.tem.2024.07.006_bb0130","doi-asserted-by":"crossref","first-page":"S63","DOI":"10.1053\/plac.2001.0642","article-title":"Hypoxia: implications for implantation to delivery \u2013 a workshop report","volume":"22","author":"Burton","year":"2001","journal-title":"Placenta"},{"key":"10.1016\/j.tem.2024.07.006_bb0135","first-page":"283","article-title":"Oxygen measurements in endometrial and trophoblastic tissues during early pregnancy","volume":"80","author":"Rodesch","year":"1992","journal-title":"Obstet. Gynecol."},{"key":"10.1016\/j.tem.2024.07.006_bb0140","doi-asserted-by":"crossref","first-page":"691","DOI":"10.1210\/endo-83-4-691","article-title":"Measurement of intrauterine oxygen tension in the rat and its regulation by ovarian steroid hormones","volume":"83","author":"Mitchell","year":"1968","journal-title":"Endocrinology"},{"key":"10.1016\/j.tem.2024.07.006_bb0145","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1038\/nrc3183","article-title":"HIF1alpha and HIF2alpha: sibling rivalry in hypoxic tumour growth and progression","volume":"12","author":"Keith","year":"2012","journal-title":"Nat. Rev. Cancer"},{"key":"10.1016\/j.tem.2024.07.006_bb0150","doi-asserted-by":"crossref","first-page":"10479","DOI":"10.1128\/MCB.25.23.10479-10491.2005","article-title":"Hypoxia-inducible factors 1alpha and 2alpha regulate trophoblast differentiation","volume":"25","author":"Cowden Dahl","year":"2005","journal-title":"Mol. Cell. Biol."},{"key":"10.1016\/j.tem.2024.07.006_bb0155","doi-asserted-by":"crossref","first-page":"7683","DOI":"10.1074\/jbc.M211390200","article-title":"Expression of hypoxia-inducible factors in the peri-implantation mouse uterus is regulated in a cell-specific and ovarian steroid hormone-dependent manner. Evidence for differential function of HIFs during early pregnancy","volume":"278","author":"Daikoku","year":"2003","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.tem.2024.07.006_bb0160","doi-asserted-by":"crossref","first-page":"2363","DOI":"10.1210\/en.2006-1394","article-title":"Estrogen-induced activation of hypoxia-inducible factor-1alpha, vascular endothelial growth factor expression, and edema in the uterus are mediated by the phosphatidylinositol 3-kinase\/Akt pathway","volume":"148","author":"Kazi","year":"2007","journal-title":"Endocrinology"},{"key":"10.1016\/j.tem.2024.07.006_bb0165","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.yexcr.2014.07.027","article-title":"Rab proteins: the key regulators of intracellular vesicle transport","volume":"328","author":"Bhuin","year":"2014","journal-title":"Exp. Cell Res."},{"key":"10.1016\/j.tem.2024.07.006_bb0170","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1083\/jcb.201306010","article-title":"Review series: Rab GTPases and membrane identity: causal or inconsequential?","volume":"202","author":"Barr","year":"2013","journal-title":"J. Cell Biol."},{"key":"10.1016\/j.tem.2024.07.006_bb0175","doi-asserted-by":"crossref","first-page":"4377","DOI":"10.1091\/mbc.e07-05-0409","article-title":"Rab27b is expressed in a wide range of exocytic cells and involved in the delivery of secretory granules near the plasma membrane","volume":"18","author":"Gomi","year":"2007","journal-title":"Mol. Biol. Cell"},{"key":"10.1016\/j.tem.2024.07.006_bb0180","doi-asserted-by":"crossref","first-page":"5872","DOI":"10.1073\/pnas.0609879104","article-title":"Rab27b regulates number and secretion of platelet dense granules","volume":"104","author":"Tolmachova","year":"2007","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.tem.2024.07.006_bb0185","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1152\/physrev.00031.2002","article-title":"Secretory granule exocytosis","volume":"83","author":"Burgoyne","year":"2003","journal-title":"Physiol. Rev."},{"key":"10.1016\/j.tem.2024.07.006_bb0190","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1083\/jcb.201211138","article-title":"Extracellular vesicles: exosomes, microvesicles, and friends","volume":"200","author":"Raposo","year":"2013","journal-title":"J. Cell Biol."},{"key":"10.1016\/j.tem.2024.07.006_bb0195","doi-asserted-by":"crossref","DOI":"10.1210\/endocr\/bqab133","article-title":"Extracellular vesicles \u2013 the next frontier in endocrinology","volume":"162","author":"Das Gupta","year":"2021","journal-title":"Endocrinology"},{"key":"10.1016\/j.tem.2024.07.006_bb0200","doi-asserted-by":"crossref","first-page":"292","DOI":"10.1210\/er.2017-00229","article-title":"Extracellular vesicles in human reproduction in health and disease","volume":"39","author":"Simon","year":"2018","journal-title":"Endocr. Rev."},{"key":"10.1016\/j.tem.2024.07.006_bb0205","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1038\/ncb2000","article-title":"Rab27a and Rab27b control different steps of the exosome secretion pathway","volume":"12","author":"Ostrowski","year":"2010","journal-title":"Nat. Cell Biol."},{"key":"10.1016\/j.tem.2024.07.006_bb0210","doi-asserted-by":"crossref","first-page":"949","DOI":"10.1111\/tra.12083","article-title":"Rab27 effectors, pleiotropic regulators in secretory pathways","volume":"14","author":"Fukuda","year":"2013","journal-title":"Traffic"},{"key":"10.1016\/j.tem.2024.07.006_bb0215","doi-asserted-by":"crossref","first-page":"925","DOI":"10.1038\/cr.2014.82","article-title":"Uterine Rbpj is required for embryonic-uterine orientation and decidual remodeling via Notch pathway-independent and -dependent mechanisms","volume":"24","author":"Zhang","year":"2014","journal-title":"Cell Res."},{"key":"10.1016\/j.tem.2024.07.006_bb0220","doi-asserted-by":"crossref","first-page":"1024","DOI":"10.1016\/j.mam.2012.07.017","article-title":"Navigating the site for embryo implantation: biomechanical and molecular regulation of intrauterine embryo distribution","volume":"34","author":"Chen","year":"2013","journal-title":"Mol. Asp. Med."},{"key":"10.1016\/j.tem.2024.07.006_bb0225","doi-asserted-by":"crossref","first-page":"2699","DOI":"10.1093\/humrep\/del212","article-title":"The effects of oxygen concentration and gestational age on extravillous trophoblast outgrowth in a human first trimester villous explant model","volume":"21","author":"James","year":"2006","journal-title":"Hum. Reprod."},{"key":"10.1016\/j.tem.2024.07.006_bb0230","doi-asserted-by":"crossref","first-page":"495","DOI":"10.4161\/cc.5.5.2497","article-title":"Hypoxia, HIF and the placenta","volume":"5","author":"Fryer","year":"2006","journal-title":"Cell Cycle"},{"key":"10.1016\/j.tem.2024.07.006_bb0235","doi-asserted-by":"crossref","first-page":"3650","DOI":"10.1242\/dev.133462","article-title":"From the stem of the placental tree: trophoblast stem cells and their progeny","volume":"143","author":"Latos","year":"2016","journal-title":"Development"},{"key":"10.1016\/j.tem.2024.07.006_bb0240","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1007\/s00018-022-04363-6","article-title":"Transcription factor networks in trophoblast development","volume":"79","author":"Papuchova","year":"2022","journal-title":"Cell. Mol. Life Sci."},{"key":"10.1016\/j.tem.2024.07.006_bb0245","doi-asserted-by":"crossref","first-page":"3191","DOI":"10.1101\/gad.853700a","article-title":"Placental cell fates are regulated in vivo by HIF-mediated hypoxia responses","volume":"14","author":"Adelman","year":"2000","journal-title":"Genes Dev."},{"key":"10.1016\/j.tem.2024.07.006_bb0250","doi-asserted-by":"crossref","first-page":"E7212","DOI":"10.1073\/pnas.1612626113","article-title":"HIF-KDM3A-MMP12 regulatory circuit ensures trophoblast plasticity and placental adaptations to hypoxia","volume":"113","author":"Chakraborty","year":"2016","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.tem.2024.07.006_bb0255","doi-asserted-by":"crossref","first-page":"R43","DOI":"10.1530\/JOE-17-0402","article-title":"Trophoblast lineage specification, differentiation and their regulation by oxygen tension","volume":"236","author":"Chang","year":"2018","journal-title":"J. Endocrinol."},{"key":"10.1016\/j.tem.2024.07.006_bb0260","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1016\/j.ydbio.2016.12.013","article-title":"Inactivation of maternal Hif-1alpha at mid-pregnancy causes placental defects and deficits in oxygen delivery to the fetal organs under hypoxic stress","volume":"422","author":"Kenchegowda","year":"2017","journal-title":"Dev. Biol."},{"key":"10.1016\/j.tem.2024.07.006_bb0265","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1093\/biolreprod\/64.2.499","article-title":"Selective overexpression of the hypoxia-inducible transcription factor, HIF-2alpha, in placentas from women with preeclampsia","volume":"64","author":"Rajakumar","year":"2001","journal-title":"Biol. Reprod."},{"key":"10.1016\/j.tem.2024.07.006_bb0270","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0186149","article-title":"Novel genes and mutations in patients affected by recurrent pregnancy loss","volume":"12","author":"Quintero-Ronderos","year":"2017","journal-title":"PLoS One"},{"key":"10.1016\/j.tem.2024.07.006_bb0275","doi-asserted-by":"crossref","first-page":"2677","DOI":"10.1093\/molbev\/msab064","article-title":"High-altitude adaptation: mechanistic insights from integrated genomics and physiology","volume":"38","author":"Storz","year":"2021","journal-title":"Mol. Biol. Evol."},{"key":"10.1016\/j.tem.2024.07.006_bb0280","doi-asserted-by":"crossref","first-page":"4037","DOI":"10.1016\/j.cub.2023.08.021","article-title":"Polygenic adaptation leads to a higher reproductive fitness of native Tibetans at high altitude","volume":"33","author":"He","year":"2023","journal-title":"Curr. Biol."},{"key":"10.1016\/j.tem.2024.07.006_bb0285","doi-asserted-by":"crossref","first-page":"11459","DOI":"10.1073\/pnas.1002443107","article-title":"Natural selection on EPAS1 (HIF2alpha) associated with low hemoglobin concentration in Tibetan highlanders","volume":"107","author":"Beall","year":"2010","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.tem.2024.07.006_bb0290","doi-asserted-by":"crossref","first-page":"614","DOI":"10.1002\/ajhb.20900","article-title":"Evolutionary adaptation to high altitude: a view from in utero","volume":"21","author":"Julian","year":"2009","journal-title":"Am. J. Hum. Biol."},{"key":"10.1016\/j.tem.2024.07.006_bb0295","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1002\/ajhb.1102","article-title":"Tibetan protection from intrauterine growth restriction (IUGR) and reproductive loss at high altitude","volume":"13","author":"Moore","year":"2001","journal-title":"Am. J. Hum. Biol."}],"container-title":["Trends in Endocrinology &amp; Metabolism"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1043276024001875?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1043276024001875?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,12,2]],"date-time":"2024-12-02T11:13:10Z","timestamp":1733137990000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1043276024001875"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,12]]},"references-count":59,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2024,12]]}},"alternative-id":["S1043276024001875"],"URL":"https:\/\/doi.org\/10.1016\/j.tem.2024.07.006","relation":{},"ISSN":["1043-2760"],"issn-type":[{"value":"1043-2760","type":"print"}],"subject":[],"published":{"date-parts":[[2024,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Maternal\u2013fetal mechanisms underlying adaptation to hypoxia during early pregnancy","name":"articletitle","label":"Article Title"},{"value":"Trends in Endocrinology & Metabolism","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.tem.2024.07.006","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Elsevier Ltd. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}