{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,18]],"date-time":"2026-10-18T00:52:26Z","timestamp":1792284746692,"version":"4.4.0"},"reference-count":130,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2027,6,1]],"date-time":"2027-06-01T00:00:00Z","timestamp":1811808000000},"content-version":"am","delay-in-days":365,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/100000054","name":"National Institutes of Health National Cancer Institute","doi-asserted-by":"publisher","award":["R01CA303068"],"award-info":[{"award-number":["R01CA303068"]}],"id":[{"id":"10.13039\/100000054","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000054","name":"National Institutes of Health National Cancer Institute","doi-asserted-by":"publisher","award":["R01CA269140"],"award-info":[{"award-number":["R01CA269140"]}],"id":[{"id":"10.13039\/100000054","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000048","name":"American Cancer Society Inc","doi-asserted-by":"publisher","award":["DBG-22-161-01-MM"],"award-info":[{"award-number":["DBG-22-161-01-MM"]}],"id":[{"id":"10.13039\/100000048","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000005","name":"US Department of Defense","doi-asserted-by":"publisher","award":["KC220138"],"award-info":[{"award-number":["KC220138"]}],"id":[{"id":"10.13039\/100000005","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100004917","name":"Cancer Prevention and Research Institute of Texas","doi-asserted-by":"publisher","award":["RP250028"],"award-info":[{"award-number":["RP250028"]}],"id":[{"id":"10.13039\/100004917","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007313","name":"University of Texas MD Anderson Cancer Center","doi-asserted-by":"publisher","award":["AGA2025-21-04"],"award-info":[{"award-number":["AGA2025-21-04"]}],"id":[{"id":"10.13039\/100007313","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000147","name":"Canadian Cancer Society","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000147","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["cell.com","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Trends in Endocrinology &amp; Metabolism"],"published-print":{"date-parts":[[2026,6]]},"DOI":"10.1016\/j.tem.2025.09.008","type":"journal-article","created":{"date-parts":[[2025,10,18]],"date-time":"2025-10-18T15:55:38Z","timestamp":1760802938000},"page":"534-549","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":9,"title":["Systemic and metabolic control of liver regeneration"],"prefix":"10.1016","volume":"37","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3954-3243","authenticated-orcid":false,"given":"Yalan","family":"Deng","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6607-4596","authenticated-orcid":false,"given":"Zilong","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9368-2957","authenticated-orcid":false,"given":"Yutong","family":"Sun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9965-989X","authenticated-orcid":false,"given":"Li","family":"Ma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.tem.2025.09.008_bb0005","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1038\/s41575-020-0342-4","article-title":"Liver regeneration: biological and pathological mechanisms and implications","volume":"18","author":"Michalopoulos","year":"2021","journal-title":"Nat. Rev. Gastroenterol. Hepatol."},{"key":"10.1016\/j.tem.2025.09.008_bb0010","doi-asserted-by":"crossref","first-page":"S45","DOI":"10.1002\/hep.20969","article-title":"Liver regeneration","volume":"43","author":"Fausto","year":"2006","journal-title":"Hepatology"},{"key":"10.1016\/j.tem.2025.09.008_bb0015","doi-asserted-by":"crossref","first-page":"608","DOI":"10.1038\/s41580-021-00373-7","article-title":"Liver regeneration and inflammation: from fundamental science to clinical applications","volume":"22","author":"Campana","year":"2021","journal-title":"Nat. Rev. Mol. Cell Biol."},{"key":"10.1016\/j.tem.2025.09.008_bb0020","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1016\/j.semcdb.2019.12.004","article-title":"Cellular and molecular basis of liver regeneration","volume":"100","author":"Bangru","year":"2020","journal-title":"Semin. Cell Dev. Biol."},{"key":"10.1016\/j.tem.2025.09.008_bb0025","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1002\/9780470942390.mo130087","article-title":"Inducing and characterizing liver regeneration in mice: reliable models, essential \u2018readouts\u2019 and critical perspectives","volume":"3","author":"Mastellos","year":"2013","journal-title":"Curr. Protoc. Mouse Biol."},{"key":"10.1016\/j.tem.2025.09.008_bb0030","doi-asserted-by":"crossref","first-page":"1167","DOI":"10.1038\/nprot.2008.80","article-title":"A reproducible and well-tolerated method for 2\/3 partial hepatectomy in mice","volume":"3","author":"Mitchell","year":"2008","journal-title":"Nat. Protoc."},{"key":"10.1016\/j.tem.2025.09.008_bb0035","doi-asserted-by":"crossref","DOI":"10.3389\/fcell.2022.903740","article-title":"Mouse models of liver parenchyma injuries and regeneration","volume":"10","author":"Du","year":"2022","journal-title":"Front. Cell Dev. Biol."},{"key":"10.1016\/j.tem.2025.09.008_bb0040","doi-asserted-by":"crossref","first-page":"470","DOI":"10.1093\/toxsci\/69.2.470","article-title":"Enhancement of allyl alcohol hepatotoxicity by endotoxin requires extrahepatic factors","volume":"69","author":"Kinser","year":"2002","journal-title":"Toxicol. Sci."},{"key":"10.1016\/j.tem.2025.09.008_bb0045","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1038\/nrgastro.2012.225","article-title":"Ischaemia-reperfusion injury in liver transplantation \u2013 from bench to bedside","volume":"10","author":"Zhai","year":"2013","journal-title":"Nat. Rev. Gastroenterol. Hepatol."},{"key":"10.1016\/j.tem.2025.09.008_bb0050","doi-asserted-by":"crossref","first-page":"9112","DOI":"10.3390\/ijms24119112","article-title":"Effect of hepatic pathology on liver regeneration: the main metabolic mechanisms causing impaired hepatic regeneration","volume":"24","author":"Rodimova","year":"2023","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.tem.2025.09.008_bb0055","doi-asserted-by":"crossref","DOI":"10.1126\/science.adj4301","article-title":"Metabolic inflexibility promotes mitochondrial health during liver regeneration","volume":"384","author":"Wang","year":"2024","journal-title":"Science"},{"key":"10.1016\/j.tem.2025.09.008_bb0060","doi-asserted-by":"crossref","first-page":"1465","DOI":"10.1053\/j.gastro.2017.12.022","article-title":"Hedgehog-YAP signaling pathway regulates glutaminolysis to control activation of hepatic stellate cells","volume":"154","author":"Du","year":"2018","journal-title":"Gastroenterology"},{"key":"10.1016\/j.tem.2025.09.008_bb0065","doi-asserted-by":"crossref","first-page":"953","DOI":"10.1038\/s41588-024-01709-7","article-title":"A spatiotemporal atlas of mouse liver homeostasis and regeneration","volume":"56","author":"Xu","year":"2024","journal-title":"Nat. Genet."},{"key":"10.1016\/j.tem.2025.09.008_bb0070","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1016\/j.stem.2024.01.013","article-title":"Region-specific cellular and molecular basis of liver regeneration after acute pericentral injury","volume":"31","author":"Wang","year":"2024","journal-title":"Cell Stem Cell"},{"key":"10.1016\/j.tem.2025.09.008_bb0075","doi-asserted-by":"crossref","first-page":"466","DOI":"10.1016\/j.jhep.2020.09.003","article-title":"Liver zonation","volume":"74","author":"Manco","year":"2021","journal-title":"J. Hepatol."},{"key":"10.1016\/j.tem.2025.09.008_bb0080","doi-asserted-by":"crossref","first-page":"957","DOI":"10.1002\/hep.23046","article-title":"Adipokines in liver diseases","volume":"50","author":"Marra","year":"2009","journal-title":"Hepatology"},{"key":"10.1016\/j.tem.2025.09.008_bb0085","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2021.775526","article-title":"The gut\u2013liver axis in health and disease: the role of gut microbiota-derived signals in liver injury and regeneration","volume":"12","author":"Zheng","year":"2021","journal-title":"Front. Immunol."},{"key":"10.1016\/j.tem.2025.09.008_bb0090","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1016\/j.jhep.2010.07.012","article-title":"Immediate neuroendocrine signaling after partial hepatectomy through acute portal hyperpressure and cholestasis","volume":"54","author":"Doignon","year":"2011","journal-title":"J. Hepatol."},{"key":"10.1016\/j.tem.2025.09.008_bb0095","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1016\/j.mayocpiqo.2020.02.001","article-title":"Hormonal contribution to liver regeneration","volume":"4","author":"Abu Rmilah","year":"2020","journal-title":"Mayo Clin. Proc. Innov. Qual. Outcomes"},{"key":"10.1016\/j.tem.2025.09.008_bb0100","doi-asserted-by":"crossref","first-page":"1100","DOI":"10.3390\/cells8091100","article-title":"New insights into the liver\u2013visceral adipose axis during hepatic resection and liver transplantation","volume":"8","author":"Cornide-Petronio","year":"2019","journal-title":"Cells"},{"key":"10.1016\/j.tem.2025.09.008_bb0105","doi-asserted-by":"crossref","first-page":"8210","DOI":"10.3390\/ijms22158210","article-title":"New insights in mechanisms and therapeutics for short- and long-term impacts of hepatic ischemia reperfusion injury post liver transplantation","volume":"22","author":"Liu","year":"2021","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.tem.2025.09.008_bb0110","doi-asserted-by":"crossref","first-page":"731","DOI":"10.1016\/j.tem.2021.06.002","article-title":"Metabolic hallmarks of liver regeneration","volume":"32","author":"Solhi","year":"2021","journal-title":"Trends Endocrinol. Metab."},{"key":"10.1016\/j.tem.2025.09.008_bb0115","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1016\/j.devcel.2018.09.020","article-title":"Metabolic remodeling during liver regeneration","volume":"47","author":"Caldez","year":"2018","journal-title":"Dev. Cell"},{"key":"10.1016\/j.tem.2025.09.008_bb0120","doi-asserted-by":"crossref","first-page":"2109","DOI":"10.1002\/hep.23920","article-title":"Liver regeneration is impaired in lipodystrophic fatty liver dystrophy mice","volume":"52","author":"Gazit","year":"2010","journal-title":"Hepatology"},{"key":"10.1016\/j.tem.2025.09.008_bb0125","doi-asserted-by":"crossref","first-page":"1246","DOI":"10.1016\/j.jhep.2013.07.025","article-title":"Delayed liver regeneration after partial hepatectomy in adipose differentiation related protein-null mice","volume":"59","author":"Kohjima","year":"2013","journal-title":"J. Hepatol."},{"key":"10.1016\/j.tem.2025.09.008_bb0130","doi-asserted-by":"crossref","first-page":"544","DOI":"10.1053\/jhep.2002.35276","article-title":"Delayed liver regeneration in peroxisome proliferator-activated receptor-alpha-null mice","volume":"36","author":"Anderson","year":"2002","journal-title":"Hepatology"},{"key":"10.1016\/j.tem.2025.09.008_bb0135","doi-asserted-by":"crossref","first-page":"G302","DOI":"10.1152\/ajpgi.00175.2002","article-title":"Impaired Ras membrane association and activation in PPARalpha knockout mice after partial hepatectomy","volume":"284","author":"Wheeler","year":"2003","journal-title":"Am. J. Physiol. Gastrointest. Liver Physiol."},{"key":"10.1016\/j.tem.2025.09.008_bb0140","doi-asserted-by":"crossref","first-page":"1005","DOI":"10.1038\/s41586-025-08778-6","article-title":"Macrophages harness hepatocyte glutamate to boost liver regeneration","volume":"641","author":"Rigual","year":"2025","journal-title":"Nature"},{"key":"10.1016\/j.tem.2025.09.008_bb0145","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/S0899-9007(98)00133-6","article-title":"Effects of glutamine administration on liver regeneration following hepatectomy","volume":"15","author":"Ito","year":"1999","journal-title":"Nutrition"},{"key":"10.1016\/j.tem.2025.09.008_bb0150","doi-asserted-by":"crossref","first-page":"2928","DOI":"10.1111\/liv.14687","article-title":"Recent advances targeting C-C chemokine receptor type 2 for liver diseases in monocyte\/macrophage","volume":"40","author":"Li","year":"2020","journal-title":"Liver Int."},{"key":"10.1016\/j.tem.2025.09.008_bb0155","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1007\/s00204-024-03886-0","article-title":"Innate immune regulation in inflammation resolution and liver regeneration in drug-induced liver injury","volume":"99","author":"Qian","year":"2025","journal-title":"Arch. Toxicol."},{"key":"10.1016\/j.tem.2025.09.008_bb0160","doi-asserted-by":"crossref","first-page":"1176","DOI":"10.3390\/ijms24021176","article-title":"Liver regeneration and immunity: a tale to tell","volume":"24","author":"Di-Iacovo","year":"2023","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.tem.2025.09.008_bb0165","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1038\/s41423-020-00558-8","article-title":"Hepatic macrophages in liver homeostasis and diseases-diversity, plasticity and therapeutic opportunities","volume":"18","author":"Wen","year":"2021","journal-title":"Cell. Mol. Immunol."},{"key":"10.1016\/j.tem.2025.09.008_bb0170","doi-asserted-by":"crossref","first-page":"971","DOI":"10.1016\/j.jcmgh.2022.05.014","article-title":"Liver regeneration in chronic liver injuries: basic and clinical applications focusing on macrophages and natural killer cells","volume":"14","author":"Qian","year":"2022","journal-title":"Cell Mol. Gastroenterol. Hepatol."},{"key":"10.1016\/j.tem.2025.09.008_bb0175","doi-asserted-by":"crossref","first-page":"316","DOI":"10.1038\/cmi.2015.104","article-title":"Hepatic macrophages in homeostasis and liver diseases: from pathogenesis to novel therapeutic strategies","volume":"13","author":"Ju","year":"2016","journal-title":"Cell. Mol. Immunol."},{"key":"10.1016\/j.tem.2025.09.008_bb0180","doi-asserted-by":"crossref","first-page":"G1310","DOI":"10.1152\/ajpgi.00365.2011","article-title":"Hepatic recruitment of macrophages promotes nonalcoholic steatohepatitis through CCR2","volume":"302","author":"Miura","year":"2012","journal-title":"Am. J. Physiol. Gastrointest. Liver Physiol."},{"key":"10.1016\/j.tem.2025.09.008_bb0185","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1002\/hep.22950","article-title":"Hepatic recruitment of the inflammatory Gr1+ monocyte subset upon liver injury promotes hepatic fibrosis","volume":"50","author":"Karlmark","year":"2009","journal-title":"Hepatology"},{"key":"10.1016\/j.tem.2025.09.008_bb0190","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1016\/j.stem.2023.01.009","article-title":"Kupffer-cell-derived IL-6 is repurposed for hepatocyte dedifferentiation via activating progenitor genes from injury-specific enhancers","volume":"30","author":"Li","year":"2023","journal-title":"Cell Stem Cell"},{"key":"10.1016\/j.tem.2025.09.008_bb0195","doi-asserted-by":"crossref","first-page":"362","DOI":"10.1016\/j.immuni.2025.01.002","article-title":"Spatially restricted and ontogenically distinct hepatic macrophages are required for tissue repair","volume":"58","author":"De Ponti","year":"2025","journal-title":"Immunity"},{"key":"10.1016\/j.tem.2025.09.008_bb0200","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1016\/j.cell.2021.12.018","article-title":"Spatial proteogenomics reveals distinct and evolutionarily conserved hepatic macrophage niches","volume":"185","author":"Guilliams","year":"2022","journal-title":"Cell"},{"key":"10.1016\/j.tem.2025.09.008_bb0205","doi-asserted-by":"crossref","first-page":"540","DOI":"10.1002\/hep4.1478","article-title":"Farnesoid X receptor activation protects liver from ischemia\/reperfusion injury by up-regulating small heterodimer partner in Kupffer cells","volume":"4","author":"Jin","year":"2020","journal-title":"Hepatol. Commun."},{"key":"10.1016\/j.tem.2025.09.008_bb0210","doi-asserted-by":"crossref","first-page":"2629","DOI":"10.1172\/JCI124616","article-title":"More friend than foe: the emerging role of neutrophils in tissue repair","volume":"129","author":"Peiseler","year":"2019","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.tem.2025.09.008_bb0215","doi-asserted-by":"crossref","first-page":"1619","DOI":"10.1016\/j.jhep.2022.07.027","article-title":"Hepatectomy-induced apoptotic extracellular vesicles stimulate neutrophils to secrete regenerative growth factors","volume":"77","author":"Brandel","year":"2022","journal-title":"J. Hepatol."},{"key":"10.1016\/j.tem.2025.09.008_bb0220","doi-asserted-by":"crossref","first-page":"1756","DOI":"10.1038\/s42255-024-01110-y","article-title":"LIFR regulates cholesterol-driven bidirectional hepatocyte-neutrophil cross-talk to promote liver regeneration","volume":"6","author":"Deng","year":"2024","journal-title":"Nat. Metab."},{"key":"10.1016\/j.tem.2025.09.008_bb0225","doi-asserted-by":"crossref","first-page":"1076","DOI":"10.1038\/s41467-019-09046-8","article-title":"Neutrophils promote the development of reparative macrophages mediated by ROS to orchestrate liver repair","volume":"10","author":"Yang","year":"2019","journal-title":"Nat. Commun."},{"key":"10.1016\/j.tem.2025.09.008_bb0230","doi-asserted-by":"crossref","first-page":"1525","DOI":"10.1053\/j.gastro.2004.08.055","article-title":"Negative regulation of liver regeneration by innate immunity (natural killer cells\/interferon-gamma)","volume":"127","author":"Sun","year":"2004","journal-title":"Gastroenterology"},{"key":"10.1016\/j.tem.2025.09.008_bb0235","doi-asserted-by":"crossref","first-page":"G275","DOI":"10.1152\/ajpgi.00026.2010","article-title":"Activation of natural killer cells inhibits liver regeneration in toxin-induced liver injury model in mice via a tumor necrosis factor-alpha-dependent mechanism","volume":"299","author":"Wei","year":"2010","journal-title":"Am. J. Physiol. Gastrointest. Liver Physiol."},{"key":"10.1016\/j.tem.2025.09.008_bb0240","doi-asserted-by":"crossref","first-page":"1192","DOI":"10.1016\/0016-5085(95)90219-8","article-title":"Effect of cholestasis and bile acids on interferon-induced 2\u2032,5\u2032-adenylate synthetase and NK cell activities","volume":"108","author":"Podevin","year":"1995","journal-title":"Gastroenterology"},{"key":"10.1016\/j.tem.2025.09.008_bb0245","doi-asserted-by":"crossref","first-page":"9914","DOI":"10.1073\/pnas.1304046110","article-title":"Eosinophils secrete IL-4 to facilitate liver regeneration","volume":"110","author":"Goh","year":"2013","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.tem.2025.09.008_bb0250","doi-asserted-by":"crossref","first-page":"344","DOI":"10.1016\/j.jhep.2022.02.024","article-title":"Hepatic recruitment of eosinophils and their protective function during acute liver injury","volume":"77","author":"Xu","year":"2022","journal-title":"J. Hepatol."},{"key":"10.1016\/j.tem.2025.09.008_bb0255","doi-asserted-by":"crossref","first-page":"27","DOI":"10.3389\/fphar.2013.00027","article-title":"Eosinophil recruitment and activation: the role of lipid mediators","volume":"4","author":"Luna-Gomes","year":"2013","journal-title":"Front. Pharmacol."},{"key":"10.1016\/j.tem.2025.09.008_bb0260","doi-asserted-by":"crossref","first-page":"1543","DOI":"10.1136\/gutjnl-2024-332033","article-title":"Novel IL-4\/HB-EGF-dependent crosstalk between eosinophils and macrophages controls liver regeneration after ischaemia and reperfusion injury","volume":"73","author":"Yang","year":"2024","journal-title":"Gut"},{"key":"10.1016\/j.tem.2025.09.008_bb0265","doi-asserted-by":"crossref","first-page":"1409","DOI":"10.1136\/gutjnl-2024-332692","article-title":"Eosinophils: a novel therapeutic target to promote liver regeneration in acute liver injury?","volume":"73","author":"Ni","year":"2024","journal-title":"Gut"},{"key":"10.1016\/j.tem.2025.09.008_bb0270","doi-asserted-by":"crossref","DOI":"10.1126\/scitranslmed.abb6576","article-title":"Eosinophils attenuate hepatic ischemia-reperfusion injury in mice through ST2-dependent IL-13 production","volume":"13","author":"Wang","year":"2021","journal-title":"Sci. Transl. Med."},{"key":"10.1016\/j.tem.2025.09.008_bb0275","doi-asserted-by":"crossref","first-page":"456","DOI":"10.1002\/hep.32609","article-title":"Eosinophils protect against acetaminophen-induced liver injury through cyclooxygenase-mediated IL-4\/IL-13 production","volume":"77","author":"Xu","year":"2023","journal-title":"Hepatology"},{"key":"10.1016\/j.tem.2025.09.008_bb0280","doi-asserted-by":"crossref","first-page":"1902","DOI":"10.1172\/JCI66369","article-title":"Hepatic stellate cells in liver development, regeneration, and cancer","volume":"123","author":"Yin","year":"2013","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.tem.2025.09.008_bb0285","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1111\/hepr.12872","article-title":"Mechanism of impairment on liver regeneration in elderly patients: role of hepatic stellate cell function","volume":"47","author":"Saito","year":"2017","journal-title":"Hepatol. Res."},{"key":"10.1016\/j.tem.2025.09.008_bb0290","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1002\/hep4.1628","article-title":"Hepatic stellate cell regulation of liver regeneration and repair","volume":"5","author":"Kitto","year":"2021","journal-title":"Hepatol. Commun."},{"key":"10.1016\/j.tem.2025.09.008_bb0295","doi-asserted-by":"crossref","first-page":"1853","DOI":"10.1126\/science.1137603","article-title":"Regulation of hepatic stellate cell differentiation by the neurotrophin receptor p75NTR","volume":"315","author":"Passino","year":"2007","journal-title":"Science"},{"key":"10.1016\/j.tem.2025.09.008_bb0300","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1038\/nrgastro.2017.38","article-title":"Mechanisms of hepatic stellate cell activation","volume":"14","author":"Tsuchida","year":"2017","journal-title":"Nat. Rev. Gastroenterol. Hepatol."},{"key":"10.1016\/j.tem.2025.09.008_bb0305","doi-asserted-by":"crossref","first-page":"752","DOI":"10.1038\/s41586-025-08677-w","article-title":"Hepatic stellate cells control liver zonation, size and functions via R-spondin 3","volume":"640","author":"Sugimoto","year":"2025","journal-title":"Nature"},{"key":"10.1016\/j.tem.2025.09.008_bb0310","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1038\/s41575-020-00411-3","article-title":"Role of liver sinusoidal endothelial cells in liver diseases","volume":"18","author":"Gracia-Sancho","year":"2021","journal-title":"Nat. Rev. Gastroenterol. Hepatol."},{"key":"10.1016\/j.tem.2025.09.008_bb0315","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1007\/s10456-025-09969-5","article-title":"The role of liver sinusoidal endothelial cells in metabolic dysfunction-associated steatotic liver diseases and liver cancer: mechanisms and potential therapies","volume":"28","author":"Mo","year":"2025","journal-title":"Angiogenesis"},{"key":"10.1016\/j.tem.2025.09.008_bb0320","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1038\/s42003-021-01936-2","article-title":"Mechanical homeostasis of liver sinusoid is involved in the initiation and termination of liver regeneration","volume":"4","author":"Ishikawa","year":"2021","journal-title":"Commun. Biol."},{"key":"10.1016\/j.tem.2025.09.008_bb0325","doi-asserted-by":"crossref","first-page":"622","DOI":"10.1016\/j.redox.2017.01.012","article-title":"Metabolic zonation of the liver: the oxygen gradient revisited","volume":"11","author":"Kietzmann","year":"2017","journal-title":"Redox Biol."},{"key":"10.1016\/j.tem.2025.09.008_bb0330","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/j.cbi.2019.03.010","article-title":"KLF2 regulates eNOS uncoupling via Nrf2\/HO-1 in endothelial cells under hypoxia and reoxygenation","volume":"305","author":"Wu","year":"2019","journal-title":"Chem. Biol. Interact."},{"key":"10.1016\/j.tem.2025.09.008_bb0335","doi-asserted-by":"crossref","first-page":"920","DOI":"10.1002\/hep.22351","article-title":"Sinusoidal endothelial cells prevent rat stellate cell activation and promote reversion to quiescence","volume":"48","author":"Deleve","year":"2008","journal-title":"Hepatology"},{"key":"10.1016\/j.tem.2025.09.008_bb0340","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1016\/j.hbpd.2022.09.007","article-title":"The role of liver sinusoidal endothelial cells in liver remodeling after injury","volume":"22","author":"Li","year":"2023","journal-title":"Hepatobiliary Pancreat. Dis. Int."},{"key":"10.1016\/j.tem.2025.09.008_bb0345","doi-asserted-by":"crossref","first-page":"1567","DOI":"10.1172\/JCI58789","article-title":"Liver sinusoidal endothelial cell progenitor cells promote liver regeneration in rats","volume":"122","author":"Wang","year":"2012","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.tem.2025.09.008_bb0350","doi-asserted-by":"crossref","first-page":"416","DOI":"10.1126\/science.1244880","article-title":"Endothelial cell-derived angiopoietin-2 controls liver regeneration as a spatiotemporal rheostat","volume":"343","author":"Hu","year":"2014","journal-title":"Science"},{"key":"10.1016\/j.tem.2025.09.008_bb0355","doi-asserted-by":"crossref","first-page":"1539","DOI":"10.1073\/pnas.85.5.1539","article-title":"Transforming growth factor beta mRNA increases during liver regeneration: a possible paracrine mechanism of growth regulation","volume":"85","author":"Braun","year":"1988","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.tem.2025.09.008_bb0360","doi-asserted-by":"crossref","first-page":"8053","DOI":"10.3390\/ijms22158053","article-title":"Critical role of LSEC in post-hepatectomy liver regeneration and failure","volume":"22","author":"De Rudder","year":"2021","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.tem.2025.09.008_bb0365","doi-asserted-by":"crossref","first-page":"1226","DOI":"10.1097\/LVT.0000000000000252","article-title":"Liver ischemia-reperfusion injury: from trigger loading to shot firing","volume":"29","author":"Felli","year":"2023","journal-title":"Liver Transpl."},{"key":"10.1016\/j.tem.2025.09.008_bb0370","first-page":"1","article-title":"The role of liver zonation in physiology, regeneration, and disease","volume":"42","author":"Panday","year":"2022","journal-title":"Semin. Liver Dis."},{"key":"10.1016\/j.tem.2025.09.008_bb0375","doi-asserted-by":"crossref","DOI":"10.1126\/science.abc4346","article-title":"Proliferation tracing reveals regional hepatocyte generation in liver homeostasis and repair","volume":"371","author":"He","year":"2021","journal-title":"Science"},{"key":"10.1016\/j.tem.2025.09.008_bb0380","doi-asserted-by":"crossref","first-page":"1158","DOI":"10.1097\/HEP.0000000000000341","article-title":"Spatial metabolomics and its application in the liver","volume":"79","author":"Santos","year":"2024","journal-title":"Hepatology"},{"key":"10.1016\/j.tem.2025.09.008_bb0385","doi-asserted-by":"crossref","DOI":"10.1126\/science.abb1625","article-title":"Liver homeostasis is maintained by midlobular zone 2 hepatocytes","volume":"371","author":"Wei","year":"2021","journal-title":"Science"},{"key":"10.1016\/j.tem.2025.09.008_bb0390","doi-asserted-by":"crossref","first-page":"1832","DOI":"10.1016\/j.celrep.2019.10.024","article-title":"Single-cell transcriptomics uncovers zonation of function in the mesenchyme during liver fibrosis","volume":"29","author":"Dobie","year":"2019","journal-title":"Cell Rep."},{"key":"10.1016\/j.tem.2025.09.008_bb0395","doi-asserted-by":"crossref","first-page":"1219","DOI":"10.1002\/hep.32408","article-title":"Liver zonation, revisited","volume":"76","author":"Paris","year":"2022","journal-title":"Hepatology"},{"key":"10.1016\/j.tem.2025.09.008_bb0400","doi-asserted-by":"crossref","DOI":"10.1111\/apha.14239","article-title":"Getting in the zone: metabolite transport across liver zones","volume":"240","author":"van de Graaf","year":"2024","journal-title":"Acta Physiol. (Oxf)"},{"key":"10.1016\/j.tem.2025.09.008_bb0405","article-title":"Aging disrupts hepatocyte zonation homeostasis in mice and humans","author":"Sinha","year":"2025","journal-title":"Hepatology"},{"key":"10.1016\/j.tem.2025.09.008_bb0410","article-title":"Single-cell spatial transcriptomics reveals a dynamic control of metabolic zonation and liver regeneration by endothelial cell Wnt2 and Wnt9b","volume":"3","author":"Hu","year":"2022","journal-title":"Cell Rep. Med."},{"key":"10.1016\/j.tem.2025.09.008_bb0415","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1146\/annurev-pathmechdis-031521-024831","article-title":"Spatiotemporal metabolic liver zonation and consequences on pathophysiology","volume":"18","author":"Martini","year":"2023","journal-title":"Annu. Rev. Pathol."},{"key":"10.1016\/j.tem.2025.09.008_bb0420","doi-asserted-by":"crossref","first-page":"352","DOI":"10.1038\/nature21065","article-title":"Single-cell spatial reconstruction reveals global division of labour in the mammalian liver","volume":"542","author":"Halpern","year":"2017","journal-title":"Nature"},{"key":"10.1016\/j.tem.2025.09.008_bb0425","doi-asserted-by":"crossref","DOI":"10.1002\/ctm2.70238","article-title":"Adipose tissue deficiency impairs transient lipid accumulation and delays liver regeneration following partial hepatectomy in male Seipin knockout mice","volume":"15","author":"Dong","year":"2025","journal-title":"Clin. Transl. Med."},{"key":"10.1016\/j.tem.2025.09.008_bb0430","doi-asserted-by":"crossref","first-page":"341","DOI":"10.21037\/hbsn-22-442","article-title":"Adipose tissue induces a better liver regeneration after living liver donation in normal weight donors","volume":"12","author":"Deeb","year":"2023","journal-title":"Hepatobiliary Surg. Nutr."},{"key":"10.1016\/j.tem.2025.09.008_bb0435","doi-asserted-by":"crossref","first-page":"338","DOI":"10.1016\/0022-4804(85)90112-X","article-title":"Hepatic fat accumulation during liver regeneration","volume":"39","author":"Stein","year":"1985","journal-title":"J. Surg. Res."},{"key":"10.1016\/j.tem.2025.09.008_bb0440","doi-asserted-by":"crossref","first-page":"1043","DOI":"10.1038\/labinvest.2009.63","article-title":"Adiponectin deficiency impairs liver regeneration through attenuating STAT3 phosphorylation in mice","volume":"89","author":"Shu","year":"2009","journal-title":"Lab. Investig."},{"key":"10.1016\/j.tem.2025.09.008_bb0445","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1016\/j.bbrc.2008.10.176","article-title":"Delayed liver regeneration after partial hepatectomy in adiponectin knockout mice","volume":"378","author":"Ezaki","year":"2009","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.tem.2025.09.008_bb0450","doi-asserted-by":"crossref","first-page":"2639","DOI":"10.3390\/ijms22052639","article-title":"Adipokines, myokines, and hepatokines: crosstalk and metabolic repercussions","volume":"22","author":"de Oliveira Dos Santos","year":"2021","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.tem.2025.09.008_bb0455","doi-asserted-by":"crossref","first-page":"1451","DOI":"10.1016\/S0016-5085(03)00270-1","article-title":"Leptin-specific mechanisms for impaired liver regeneration in ob\/ob mice after toxic injury","volume":"124","author":"Leclercq","year":"2003","journal-title":"Gastroenterology"},{"key":"10.1016\/j.tem.2025.09.008_bb0460","doi-asserted-by":"crossref","first-page":"1161","DOI":"10.1038\/labinvest.3700474","article-title":"Defective hepatic regeneration after partial hepatectomy in leptin-deficient mice is not rescued by exogenous leptin","volume":"86","author":"Leclercq","year":"2006","journal-title":"Lab. Investig."},{"key":"10.1016\/j.tem.2025.09.008_bb0465","doi-asserted-by":"crossref","first-page":"3395","DOI":"10.3390\/ijms19113395","article-title":"The role of adipokines in surgical procedures requiring both liver regeneration and vascular occlusion","volume":"19","author":"Alvarez-Mercado","year":"2018","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.tem.2025.09.008_bb0470","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/j.jhep.2013.07.041","article-title":"Resistin and visfatin in steatotic and non-steatotic livers in the setting of partial hepatectomy under ischemia-reperfusion","volume":"60","author":"Elias-Miro","year":"2014","journal-title":"J. Hepatol."},{"key":"10.1016\/j.tem.2025.09.008_bb0475","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1016\/j.jss.2009.06.043","article-title":"Significance of insulin signaling in liver regeneration triggered by portal vein ligation","volume":"166","author":"Tseng","year":"2011","journal-title":"J. Surg. Res."},{"key":"10.1016\/j.tem.2025.09.008_bb0480","doi-asserted-by":"crossref","first-page":"1241","DOI":"10.1016\/S0140-6736(75)92076-0","article-title":"Intraportal insulin protects from the liver injury of portacaval shunt in dogs","volume":"2","author":"Starzl","year":"1975","journal-title":"Lancet"},{"key":"10.1016\/j.tem.2025.09.008_bb0485","doi-asserted-by":"crossref","first-page":"773","DOI":"10.1096\/fj.05-4704fje","article-title":"Hepatocyte proliferation during liver regeneration is impaired in mice with liver-specific IGF-1R knockout","volume":"20","author":"Desbois-Mouthon","year":"2006","journal-title":"FASEB J."},{"key":"10.1016\/j.tem.2025.09.008_bb0490","doi-asserted-by":"crossref","first-page":"376","DOI":"10.1111\/j.1365-2362.1986.tb01012.x","article-title":"Hepatic regeneration and metabolism after partial hepatectomy in normal rats: effects of insulin therapy","volume":"16","author":"Johnston","year":"1986","journal-title":"Eur. J. Clin. Investig."},{"key":"10.1016\/j.tem.2025.09.008_bb0495","doi-asserted-by":"crossref","first-page":"332","DOI":"10.1016\/0168-8278(90)90141-D","article-title":"Failure of insulin and glucagon infusion to stimulate liver regeneration in fulminant hepatic failure","volume":"10","author":"Harrison","year":"1990","journal-title":"J. Hepatol."},{"key":"10.1016\/j.tem.2025.09.008_bb0500","first-page":"685","article-title":"Rat liver regeneration after partial hepatectomy: effects of insulin, glucagon and epidermal growth factor","volume":"91","author":"Lai","year":"1992","journal-title":"J. Formos. Med. Assoc."},{"key":"10.1016\/j.tem.2025.09.008_bb0505","doi-asserted-by":"crossref","first-page":"2512","DOI":"10.3390\/ijms20102512","article-title":"Somatostatin and the \u2018small-for-size\u2019 liver","volume":"20","author":"Hessheimer","year":"2019","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.tem.2025.09.008_bb0510","doi-asserted-by":"crossref","first-page":"679","DOI":"10.1016\/0016-5085(84)90543-2","article-title":"Pancreatic hormone profiles and metabolism posthepatectomy in the dog. Evidence for a hepatotrophic role of insulin, glucagon, and pancreatic polypeptide","volume":"87","author":"Cohen","year":"1984","journal-title":"Gastroenterology"},{"key":"10.1016\/j.tem.2025.09.008_bb0515","doi-asserted-by":"crossref","first-page":"641","DOI":"10.1016\/j.jhep.2015.09.022","article-title":"Functional analysis of the relationship between intestinal microbiota and the expression of hepatic genes and pathways during the course of liver regeneration","volume":"64","author":"Liu","year":"2016","journal-title":"J. Hepatol."},{"key":"10.1016\/j.tem.2025.09.008_bb0520","article-title":"The role of gut microbiota in liver regeneration","volume":"13","author":"Xu","year":"2022","journal-title":"Front. Immunol."},{"key":"10.1016\/j.tem.2025.09.008_bb0525","doi-asserted-by":"crossref","first-page":"820","DOI":"10.1016\/j.jhep.2022.12.028","article-title":"Gut microbiota promote liver regeneration through hepatic membrane phospholipid biosynthesis","volume":"78","author":"Yin","year":"2023","journal-title":"J. Hepatol."},{"key":"10.1016\/j.tem.2025.09.008_bb0530","doi-asserted-by":"crossref","first-page":"694","DOI":"10.1016\/j.jhep.2021.10.015","article-title":"Hallmarks of the human intestinal microbiome on liver maturation and function","volume":"76","author":"Almeida","year":"2022","journal-title":"J. Hepatol."},{"key":"10.1016\/j.tem.2025.09.008_bb0535","doi-asserted-by":"crossref","first-page":"11312","DOI":"10.1074\/jbc.M211609200","article-title":"The orphan G protein-coupled receptors GPR41 and GPR43 are activated by propionate and other short chain carboxylic acids","volume":"278","author":"Brown","year":"2003","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.tem.2025.09.008_bb0540","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1126\/science.1121435","article-title":"Nuclear receptor-dependent bile acid signaling is required for normal liver regeneration","volume":"312","author":"Huang","year":"2006","journal-title":"Science"},{"key":"10.1016\/j.tem.2025.09.008_bb0545","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1016\/j.jhep.2012.08.002","article-title":"Bile acid transporters and regulatory nuclear receptors in the liver and beyond","volume":"58","author":"Halilbasic","year":"2013","journal-title":"J. Hepatol."},{"key":"10.1016\/j.tem.2025.09.008_bb0550","doi-asserted-by":"crossref","first-page":"1451","DOI":"10.1002\/hep.26463","article-title":"The receptor TGR5 protects the liver from bile acid overload during liver regeneration in mice","volume":"58","author":"Pean","year":"2013","journal-title":"Hepatology"},{"key":"10.1016\/j.tem.2025.09.008_bb0555","doi-asserted-by":"crossref","first-page":"949","DOI":"10.1016\/j.jhep.2013.01.003","article-title":"Modulation of the fecal bile acid profile by gut microbiota in cirrhosis","volume":"58","author":"Kakiyama","year":"2013","journal-title":"J. Hepatol."},{"key":"10.1016\/j.tem.2025.09.008_bb0560","first-page":"G439","article-title":"Role of the hepatic branch of the vagus nerve in liver regeneration in rats","volume":"253","author":"Tanaka","year":"1987","journal-title":"Am. J. Phys."},{"key":"10.1016\/j.tem.2025.09.008_bb0565","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1155\/1993\/59691","article-title":"Hepatic branch vagotomy can suppress liver regeneration in partially hepatectomized rats","volume":"6","author":"Ohtake","year":"1993","journal-title":"HPB Surg."},{"key":"10.1016\/j.tem.2025.09.008_bb0570","doi-asserted-by":"crossref","first-page":"2866","DOI":"10.4240\/wjgs.v15.i12.2866","article-title":"Hepatic vagotomy blunts liver regeneration after hepatectomy by downregulating the expression of interleukin-22","volume":"15","author":"Zhou","year":"2023","journal-title":"World J. Gastrointest. Surg."},{"key":"10.1016\/j.tem.2025.09.008_bb0575","doi-asserted-by":"crossref","first-page":"5300","DOI":"10.1038\/s41467-018-07747-0","article-title":"Vagus\u2013macrophage\u2013hepatocyte link promotes post-injury liver regeneration and whole-body survival through hepatic FoxM1 activation","volume":"9","author":"Izumi","year":"2018","journal-title":"Nat. Commun."},{"key":"10.1016\/j.tem.2025.09.008_bb0580","doi-asserted-by":"crossref","first-page":"16881","DOI":"10.1073\/pnas.252570299","article-title":"The Forkhead Box m1b transcription factor is essential for hepatocyte DNA replication and mitosis during mouse liver regeneration","volume":"99","author":"Wang","year":"2002","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.tem.2025.09.008_bb0585","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1007\/BF00374748","article-title":"Facilitation of liver regeneration after partial hepatectomy by ventromedial hypothalamic lesions in rats","volume":"428","author":"Kiba","year":"1994","journal-title":"Pflugers Arch."},{"key":"10.1016\/j.tem.2025.09.008_bb0590","doi-asserted-by":"crossref","first-page":"666","DOI":"10.1007\/BF00386160","article-title":"Lateral hypothalamic lesions facilitate hepatic regeneration after partial hepatectomy in rats","volume":"430","author":"Kiba","year":"1995","journal-title":"Pflugers Arch."},{"key":"10.1016\/j.tem.2025.09.008_bb0595","doi-asserted-by":"crossref","DOI":"10.1038\/s41467-024-54827-5","article-title":"A brain-to-liver signal mediates the inhibition of liver regeneration under chronic stress in mice","volume":"15","author":"Zhou","year":"2024","journal-title":"Nat. Commun."},{"key":"10.1016\/j.tem.2025.09.008_bb0600","first-page":"G321","article-title":"Vasopressin modulates liver regeneration in the Brattleboro rat","volume":"245","author":"Russell","year":"1983","journal-title":"Am. J. Phys."},{"key":"10.1016\/j.tem.2025.09.008_bb0605","doi-asserted-by":"crossref","first-page":"1901","DOI":"10.1096\/fj.03-0082fje","article-title":"Hypothalamic vasopressin release and hepatocyte Ca2+ signaling during liver regeneration: an interplay stimulating liver growth and bile flow","volume":"17","author":"Nicou","year":"2003","journal-title":"FASEB J."},{"key":"10.1016\/j.tem.2025.09.008_bb0610","doi-asserted-by":"crossref","first-page":"91","DOI":"10.3389\/fphys.2020.00091","article-title":"Exercise-released myokines in the control of energy metabolism","volume":"11","author":"Laurens","year":"2020","journal-title":"Front. Physiol."},{"key":"10.1016\/j.tem.2025.09.008_bb0615","doi-asserted-by":"crossref","first-page":"1363","DOI":"10.3390\/antiox13111363","article-title":"Myokines and their potential protective role against oxidative stress in metabolic dysfunction-associated steatotic liver disease (MASLD)","volume":"13","author":"Bucarey","year":"2024","journal-title":"Antioxidants (Basel)"},{"key":"10.1016\/j.tem.2025.09.008_bb0620","doi-asserted-by":"crossref","DOI":"10.1016\/j.biopha.2024.116452","article-title":"The role of amino acid metabolism in autoimmune hepatitis","volume":"173","author":"Xiang","year":"2024","journal-title":"Biomed. Pharmacother."},{"key":"10.1016\/j.tem.2025.09.008_bb0625","doi-asserted-by":"crossref","first-page":"704","DOI":"10.1053\/j.gastro.2009.05.009","article-title":"Bone marrow progenitor cells repair rat hepatic sinusoidal endothelial cells after liver injury","volume":"137","author":"Harb","year":"2009","journal-title":"Gastroenterology"},{"key":"10.1016\/j.tem.2025.09.008_bb0630","doi-asserted-by":"crossref","first-page":"3587","DOI":"10.1038\/s41598-018-21961-2","article-title":"Pharmacological mobilization of endogenous bone marrow stem cells promotes liver regeneration after extensive liver resection in rats","volume":"8","author":"Zhai","year":"2018","journal-title":"Sci. Rep."},{"key":"10.1016\/j.tem.2025.09.008_bb0635","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1038\/s41575-024-00913-4","article-title":"Cell senescence in liver diseases: pathological mechanism and theranostic opportunity","volume":"21","author":"Sanfeliu-Redondo","year":"2024","journal-title":"Nat. Rev. Gastroenterol. Hepatol."},{"key":"10.1016\/j.tem.2025.09.008_bb0640","doi-asserted-by":"crossref","first-page":"1290","DOI":"10.1038\/s42255-021-00483-8","article-title":"The metabolic roots of senescence: mechanisms and opportunities for intervention","volume":"3","author":"Wiley","year":"2021","journal-title":"Nat. Metab."},{"key":"10.1016\/j.tem.2025.09.008_bb0645","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1101\/gad.332643.119","article-title":"The senotherapeutic drug ABT-737 disrupts aberrant p21 expression to restore liver regeneration in adult mice","volume":"34","author":"Ritschka","year":"2020","journal-title":"Genes Dev."},{"key":"10.1016\/j.tem.2025.09.008_bb0650","doi-asserted-by":"crossref","DOI":"10.1007\/s10787-025-01867-y","article-title":"Immunopharmacology of senescence: targeting the senescence-associated secretory phenotype (SASP)-a mechanism-based review","author":"Sahu","year":"2025","journal-title":"Inflammopharmacology"}],"container-title":["Trends in Endocrinology &amp; Metabolism"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1043276025002000?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1043276025002000?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T15:22:26Z","timestamp":1780327346000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1043276025002000"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,6]]},"references-count":130,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2026,6]]}},"alternative-id":["S1043276025002000"],"URL":"https:\/\/doi.org\/10.1016\/j.tem.2025.09.008","relation":{},"ISSN":["1043-2760"],"issn-type":[{"value":"1043-2760","type":"print"}],"subject":[],"published":{"date-parts":[[2026,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Systemic and metabolic control of liver regeneration","name":"articletitle","label":"Article Title"},{"value":"Trends in Endocrinology & Metabolism","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.tem.2025.09.008","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Elsevier Ltd. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}