{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T14:54:45Z","timestamp":1792508085327,"version":"4.5.0"},"reference-count":37,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2020,5,1]],"date-time":"2020-05-01T00:00:00Z","timestamp":1588291200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,5,1]],"date-time":"2020-05-01T00:00:00Z","timestamp":1588291200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Therapies"],"published-print":{"date-parts":[[2020,5]]},"DOI":"10.1016\/j.therap.2019.09.001","type":"journal-article","created":{"date-parts":[[2019,9,9]],"date-time":"2019-09-09T11:10:16Z","timestamp":1568027416000},"page":"281-294","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"title":["Thiamine et trouble de l\u2019usage d\u2019alcool\u00a0: une enqu\u00eate de pratique nationale"],"prefix":"10.1016","volume":"75","author":[{"given":"Laura","family":"Collet","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Micha\u00ebl","family":"Bisch","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarah","family":"Viennet","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raymund","family":"Schwan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fran\u00e7ois","family":"Paille","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"17\u201318","key":"10.1016\/j.therap.2019.09.001_bib0190","first-page":"163","article-title":"Mortalit\u00e9 attribuable \u00e0 l\u2019alcool en France en 2009","volume":"16","author":"Gu\u00e9rin","year":"2013","journal-title":"BEH"},{"key":"10.1016\/j.therap.2019.09.001_bib0195","first-page":"5","article-title":"M\u00e9susage de l\u2019alcool d\u00e9pistage, diagnostic et traitement. Recommandation de bonne pratique","volume":"37","author":"Soci\u00e9t\u00e9 fran\u00e7aise d\u2019alcoologie SFA","year":"2015","journal-title":"Alcoologie Addictologie"},{"issue":"5","key":"10.1016\/j.therap.2019.09.001_bib0200","doi-asserted-by":"crossref","first-page":"442","DOI":"10.1016\/S1474-4422(07)70104-7","article-title":"Wernicke's encephalopathy: new clinical settings and recent advances in diagnosis and management","volume":"6","author":"Sechi","year":"2007","journal-title":"Lancet Neurol"},{"issue":"1","key":"10.1016\/j.therap.2019.09.001_bib0205","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1093\/alcalc\/35.Supplement_1.2","article-title":"Mechanisms of vitamin deficiency in chronic alcohol misusers and the development of the Wernicke-Korsakoff syndrome","volume":"35","author":"Thomson","year":"2000","journal-title":"Alcohol Alcohol Oxf Oxfs Suppl"},{"issue":"1","key":"10.1016\/j.therap.2019.09.001_bib0210","first-page":"34","article-title":"Patterns of 35S-thiamine hydrochloride absorption in the malnourished alcoholic patient","volume":"76","author":"Thomson","year":"1970","journal-title":"J Lab Clin Med"},{"issue":"5","key":"10.1016\/j.therap.2019.09.001_bib0215","doi-asserted-by":"crossref","first-page":"1084","DOI":"10.1111\/j.1530-0277.1993.tb05668.x","article-title":"Thiamine-dependent enzyme changes in the brains of alcoholics: relationship to the Wernicke-Korsakoff syndrome","volume":"17","author":"Butterworth","year":"1993","journal-title":"Alcohol Clin Exp Res"},{"issue":"1","key":"10.1016\/j.therap.2019.09.001_bib0220","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1097\/01.ADM.0000435320.72857.c8","article-title":"Prescribing thiamine to inpatients with alcohol use disorders: how well are we doing?","volume":"8","author":"Isenberg-Grzeda","year":"2014","journal-title":"J Addict Med"},{"issue":"9","key":"10.1016\/j.therap.2019.09.001_bib0225","doi-asserted-by":"crossref","first-page":"911","DOI":"10.1111\/imj.12522","article-title":"Thiamine in the treatment of Wernicke encephalopathy in patients with alcohol use disorders","volume":"44","author":"Latt","year":"2014","journal-title":"Intern Med J"},{"issue":"1","key":"10.1016\/j.therap.2019.09.001_bib0230","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1136\/jnnp.62.1.51","article-title":"Operational criteria for the classification of chronic alcoholics: identification of Wernicke's encephalopathy","volume":"62","author":"Caine","year":"1997","journal-title":"J Neurol Neurosurg Psychiatry"},{"issue":"12","key":"10.1016\/j.therap.2019.09.001_bib0235","doi-asserted-by":"crossref","first-page":"1408","DOI":"10.1111\/j.1468-1331.2010.03153.x","article-title":"EFNS guidelines for diagnosis, therapy and prevention of Wernicke encephalopathy","volume":"17","author":"Galvin","year":"2010","journal-title":"Eur J Neurol"},{"issue":"7","key":"10.1016\/j.therap.2019.09.001_bib0240","first-page":"CD004033","article-title":"Thiamine for prevention and treatment of Wernicke-Korsakoff Syndrome in people who abuse alcohol","author":"Day","year":"2013","journal-title":"Cochrane Database Syst Rev"},{"key":"10.1016\/j.therap.2019.09.001_bib0245","series-title":"Guidelines for the treatment of alcohol problems","author":"Haber","year":"2009"},{"issue":"26","key":"10.1016\/j.therap.2019.09.001_bib0250","first-page":"1740","article-title":"Pr\u00e9valence, prophylaxie et traitement de l\u2019enc\u00e9phalopathie de Gayet-Wernicke. Quelle dose et quel mode d\u2019administration de la thiamine\u00a0?","volume":"1","author":"Meier","year":"2005","journal-title":"Rev Med Suisse"},{"key":"10.1016\/j.therap.2019.09.001_bib0255","article-title":"Review of the effectiveness of treatment for alcohol problems","volume":"212","author":"Duncan","year":"2006","journal-title":"Natl Health Serv Natl Treat Agency Subst Misuse"},{"issue":"7","key":"10.1016\/j.therap.2019.09.001_bib0260","doi-asserted-by":"crossref","first-page":"899","DOI":"10.1177\/0269881112444324","article-title":"BAP updated guidelines: evidence-based guidelines for the pharmacological management of substance abuse, harmful use, addiction and comorbidity: recommendations from BAP","volume":"26","author":"Lingford-Hughes","year":"2012","journal-title":"J Psychopharmacol"},{"key":"10.1016\/j.therap.2019.09.001_bib0265","series-title":"Circulaire no\u00a0DHOS\/O2\/2008\/299\u00a0du 26\u00a0septembre 2008\u00a0relative \u00e0 la fili\u00e8re hospitali\u00e8re de soins en addictologie","author":"R\u00e9publique fran\u00e7aise-minist\u00e8re de la Sant\u00e9 et des Solidarit\u00e9s","year":"2008"},{"key":"10.1016\/j.therap.2019.09.001_bib0270","series-title":"Enqu\u00eate 2015\u00a0SFA, pratiques cliniques en alcoologie, confrontation des prises en charges valid\u00e9es et des prises en charge effectives. Communication pr\u00e9sent\u00e9e aux journ\u00e9es de la SFA, les acteurs de terrain aux c\u00f4t\u00e9s du patient","author":"Brouzes","year":"2015"},{"issue":"4","key":"10.1016\/j.therap.2019.09.001_bib0275","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1093\/oxfordjournals.alcalc.a008400","article-title":"B Vitamin deficiency and neuropsychiatric syndromes in alcohol misuse","volume":"33","author":"Cook","year":"1998","journal-title":"Alcohol Alcohol"},{"issue":"Part 1","key":"10.1016\/j.therap.2019.09.001_bib0280","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1016\/j.lpm.2016.07.025","article-title":"Le traitement par thiamine (vitamine B1) dans l\u2019alcoolod\u00e9pendance","volume":"46","author":"Dervaux","year":"2017","journal-title":"Presse Med"},{"issue":"3","key":"10.1016\/j.therap.2019.09.001_bib0285","doi-asserted-by":"crossref","first-page":"580","DOI":"10.1038\/npp.2010.189","article-title":"Signs of preclinical Wernicke's encephalopathy and thiamine levels as predictors of neuropsychological deficits in alcoholism without Korsakoff's syndrome","volume":"36","author":"Pitel","year":"2011","journal-title":"Neuropsychopharmacology"},{"issue":"1","key":"10.1016\/j.therap.2019.09.001_bib0290","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1093\/alcalc\/ags120","article-title":"Supplementary thiamine is still important in alcohol dependence","volume":"48","author":"Rees","year":"2013","journal-title":"Alcohol Alcohol"},{"issue":"2S","key":"10.1016\/j.therap.2019.09.001_bib0295","first-page":"1S","article-title":"Objectifs, indications et modalit\u00e9s du sevrage du patient alcoolod\u00e9pendant. Conf\u00e9rence de consensus 1999","volume":"21","author":"Soci\u00e9t\u00e9 fran\u00e7aise d\u2019alcoologie","year":"1999","journal-title":"Alcoologie Addictologie"},{"issue":"4","key":"10.1016\/j.therap.2019.09.001_bib0300","first-page":"335","article-title":"Troubles de l\u2019usage de l\u2019alcool et troubles cognitifs","volume":"36","author":"Groupe de travail du Coll\u00e8ge professionnel des acteurs de l\u2019addictologie hospitali\u00e8re - COPAAH","year":"2014","journal-title":"Alcoologie Addictologie"},{"key":"10.1016\/j.therap.2019.09.001_bib0305","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1016\/j.tiv.2017.07.009","article-title":"The vitamin B6\u00a0paradox: Supplementation with high concentrations of pyridoxine leads to decreased vitamin B6\u00a0function","volume":"44","author":"Vrolijk","year":"2017","journal-title":"Toxicol In Vitro"},{"issue":"3","key":"10.1016\/j.therap.2019.09.001_bib0310","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1007\/s12576-019-00659-8","article-title":"Improvement of pyridoxine-induced peripheral neuropathy by Cichorium intybus hydroalcoholic extract through GABAergic system","volume":"69","author":"Hasannejad","year":"2019","journal-title":"J Physiol Sci"},{"issue":"46","key":"10.1016\/j.therap.2019.09.001_bib0315","first-page":"2545","article-title":"How much vitamin B6\u00a0is toxic?","volume":"149","author":"Katan","year":"2005","journal-title":"Ned Tijdschr Geneeskd"},{"issue":"3","key":"10.1016\/j.therap.2019.09.001_bib0320","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1016\/j.encep.2016.04.011","article-title":"Thiamine et enc\u00e9phalopathie de Gayet-Wernicke\u00a0: quelles r\u00e8gles de prescription\u00a0?","volume":"43","author":"Boulanger","year":"2017","journal-title":"Encephale"},{"issue":"3","key":"10.1016\/j.therap.2019.09.001_bib0325","article-title":"Wernicke's encephalopathy: increasing clinician awareness of this serious, enigmatic, yet treatable disease","volume":"17","author":"Flynn","year":"2015","journal-title":"Prim Care Companion CNS Disord"},{"issue":"6","key":"10.1016\/j.therap.2019.09.001_bib0330","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1093\/alcalc\/37.6.513","article-title":"The Royal College of Physicians report on alcohol: guidelines for managing Wernicke's encephalopathy in the accident and Emergency Department","volume":"37","author":"Thomson","year":"2002","journal-title":"Alcohol Alcohol"},{"issue":"2","key":"10.1016\/j.therap.2019.09.001_bib0335","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1016\/0735-6757(92)90054-2","article-title":"Is intravenous thiamine safe?","volume":"10","author":"Wrenn","year":"1992","journal-title":"Am J Emerg Med"},{"issue":"1\u20132","key":"10.1016\/j.therap.2019.09.001_bib0340","first-page":"26","article-title":"L\u2019injection en psychiatrie\u00a0: de la mauvaise image au bon usage\u2026\u00a0?","volume":"5","author":"Navarre-Coulaud","year":"2009","journal-title":"Lett Psychiatre"},{"issue":"2","key":"10.1016\/j.therap.2019.09.001_bib0345","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1080\/15622975.2016.1246752","article-title":"Guidelines for biological treatment of substance use and related disorders, part 1: Alcoholism, first revision","volume":"18","author":"Soyka","year":"2017","journal-title":"World J Biol Psychiatry"},{"issue":"2","key":"10.1016\/j.therap.2019.09.001_bib0350","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1093\/alcalc\/agh250","article-title":"The treatment of patients at risk of developing Wernicke's encephalopathy in the community","volume":"41","author":"Thomson","year":"2006","journal-title":"Alcohol Alcohol"},{"key":"10.1016\/j.therap.2019.09.001_bib0355","series-title":"Trait\u00e9 d\u2019addictologie","article-title":"Conduites d\u2019alcoolisation et pathologies psychiatriques","author":"Tremey","year":"2016"},{"issue":"19","key":"10.1016\/j.therap.2019.09.001_bib0360","doi-asserted-by":"crossref","first-page":"2511","DOI":"10.1001\/jama.1990.03450190043026","article-title":"Comorbidity of mental disorders with alcohol and other drug abuse. Results from the Epidemiologic Catchment Area (ECA) Study","volume":"264","author":"Regier","year":"1990","journal-title":"JAMA"},{"issue":"4","key":"10.1016\/j.therap.2019.09.001_bib0365","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1001\/archpsyc.1997.01830160031005","article-title":"Lifetime co-occurrence of DSM-III-R alcohol abuse and dependence with other psychiatric disorders in the National Comorbidity Survey","volume":"54","author":"Kessler","year":"1997","journal-title":"Arch Gen Psychiatry"},{"key":"10.1016\/j.therap.2019.09.001_bib0185","first-page":"21","article-title":"Wernicke's encephalopathy: role of thiamine","volume":"23","author":"Thomson","year":"2009","journal-title":"Prat Gastroenterol"}],"container-title":["Therapies"],"original-title":[],"language":"fr","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0040595719301404?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0040595719301404?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,22]],"date-time":"2025-09-22T18:53:30Z","timestamp":1758567210000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0040595719301404"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,5]]},"references-count":37,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2020,5]]}},"alternative-id":["S0040595719301404"],"URL":"https:\/\/doi.org\/10.1016\/j.therap.2019.09.001","relation":{},"ISSN":["0040-5957"],"issn-type":[{"value":"0040-5957","type":"print"}],"subject":[],"published":{"date-parts":[[2020,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Thiamine et trouble de l\u2019usage d\u2019alcool\u00a0: une enqu\u00eate de pratique nationale","name":"articletitle","label":"Article Title"},{"value":"Therapies","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.therap.2019.09.001","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 Soci\u00e9t\u00e9 fran\u00e7aise de pharmacologie et de th\u00e9rapeutique. Published by Elsevier Masson SAS. All rights reserved.","name":"copyright","label":"Copyright"}]}}