{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,22]],"date-time":"2025-09-22T19:10:06Z","timestamp":1758568206766,"version":"3.44.0"},"reference-count":14,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2021,5,1]],"date-time":"2021-05-01T00:00:00Z","timestamp":1619827200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,5,1]],"date-time":"2021-05-01T00:00:00Z","timestamp":1619827200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Therapies"],"published-print":{"date-parts":[[2021,5]]},"DOI":"10.1016\/j.therap.2020.02.015","type":"journal-article","created":{"date-parts":[[2020,2,21]],"date-time":"2020-02-21T13:33:54Z","timestamp":1582292034000},"page":"253-255","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["Une lentiginose aggrav\u00e9e par la cap\u00e9citabine"],"prefix":"10.1016","volume":"76","author":[{"given":"Safa","family":"Idoudi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lobna","family":"Boussofara","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marwen","family":"Belkahla","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nadia","family":"Ghariani Fetoui","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Najet","family":"Ghariani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Colandane","family":"Belajouza","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohamed","family":"Denguezli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"6","key":"10.1016\/j.therap.2020.02.015_bib0075","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1016\/j.therap.2019.09.004","article-title":"Pharmacovigilance: the next chapter","volume":"74","author":"Moore","year":"2019","journal-title":"Therapies"},{"key":"10.1016\/j.therap.2020.02.015_bib0080","doi-asserted-by":"crossref","first-page":"1031","DOI":"10.1056\/NEJM194912292412601","article-title":"Generalized intestinal polyposis and melanin spots of the oral mucosa, lips and digits; a syndrome of diagnostic significance","volume":"241","author":"Jeghers","year":"1949","journal-title":"N Engl J Med"},{"issue":"1","key":"10.1016\/j.therap.2020.02.015_bib0085","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1111\/j.1365-2133.2004.06280.x","article-title":"Does topical tacrolimus induce lentigines in children with atopic dermatitis? A report of three cases","volume":"152","author":"Hickey","year":"2005","journal-title":"Br J Dermatol"},{"issue":"5","key":"10.1016\/j.therap.2020.02.015_bib0090","doi-asserted-by":"crossref","first-page":"831","DOI":"10.1517\/14740338.2010.511610","article-title":"Safety of capecitabine: a review","volume":"9","author":"Mikhail","year":"2010","journal-title":"Expert Opin Drug Saf"},{"key":"10.1016\/j.therap.2020.02.015_bib0095","doi-asserted-by":"crossref","first-page":"491","DOI":"10.1016\/S0001-7310(07)70114-X","article-title":"Capecitabine induced hyperpigmentation","volume":"98","author":"V\u00e1zquez-Bayo","year":"2007","journal-title":"Actas Dermosifiliogr"},{"issue":"5","key":"10.1016\/j.therap.2020.02.015_bib0100","doi-asserted-by":"crossref","first-page":"326","DOI":"10.4103\/0253-7613.70401","article-title":"An unusual case of capecitabine hyperpigmentation: is hyperpigmentation a part of hand-foot syndrome or a separate entity?","volume":"42","author":"Vasudevan","year":"2010","journal-title":"Indian J Pharmacol"},{"key":"10.1016\/j.therap.2020.02.015_bib0105","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1080\/15569520802355774","article-title":"Hand-and-foot syndrome in an African American patient treated with capecitabine with normal DPD activity: is there an ethnic disparity?","volume":"27","author":"Saif","year":"2008","journal-title":"Cutan Ocul Toxicol"},{"key":"10.1016\/j.therap.2020.02.015_bib0110","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1093\/annonc\/mdg050","article-title":"Taxane-induced nail changes: incidence, clinical presentation, outcome","volume":"14","author":"Minisini","year":"2003","journal-title":"Ann Oncol"},{"issue":"10","key":"10.1016\/j.therap.2020.02.015_bib0115","doi-asserted-by":"crossref","first-page":"1434","DOI":"10.1111\/j.1468-3083.2007.02242.x","article-title":"Capecitabine-induced hand\u2013foot syndrome and cutaneous hyperpigmentation in an elderly vitiligo patient","volume":"21","author":"Tavares-Bello","year":"2007","journal-title":"J Eur Acad Dermatol Venereol"},{"key":"10.1016\/j.therap.2020.02.015_bib0120","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1046\/j.1523-1747.1999.00551.x","article-title":"Somatic mutations in the Peutz-Jeghers (LKB1\/STKII) gene in sporadic malignant melanomas","volume":"112","author":"Rowan","year":"1999","journal-title":"J Invest Dermatol"},{"issue":"7","key":"10.1016\/j.therap.2020.02.015_bib0125","doi-asserted-by":"crossref","first-page":"975","DOI":"10.1136\/gut.2009.198499","article-title":"Peutz-Jeghers syndrome: a systematic review and recommendations for management","volume":"59","author":"Beggs","year":"2010","journal-title":"Gut"},{"issue":"2","key":"10.1016\/j.therap.2020.02.015_bib0130","doi-asserted-by":"crossref","first-page":"79","DOI":"10.5826\/dpc.0502a14","article-title":"Benign dermoscopic parallel ridge pattern in plantar hyperpigmentation due to capecitabine","volume":"5","author":"Tognetti","year":"2015","journal-title":"Dermatol Pract Concept"},{"issue":"3","key":"10.1016\/j.therap.2020.02.015_bib0135","doi-asserted-by":"crossref","first-page":"e12853","DOI":"10.1111\/dth.12853","article-title":"Capecitabine-induced eruptive acral hyperpigmentation: clinical and dermoscopic evaluation of two cases","volume":"32","author":"Peccerillo","year":"2019","journal-title":"Dermatol Ther"},{"issue":"4","key":"10.1016\/j.therap.2020.02.015_bib0070","doi-asserted-by":"crossref","first-page":"646","DOI":"10.1590\/abd1806-4841.20132058","article-title":"Parallel ridge pattern on dermoscopy: observation in non-melanoma cases","volume":"88","author":"Fracaroli","year":"2013","journal-title":"An Bras Dermatol"}],"container-title":["Therapies"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0040595720300299?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0040595720300299?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,22]],"date-time":"2025-09-22T18:54:22Z","timestamp":1758567262000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0040595720300299"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,5]]},"references-count":14,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2021,5]]}},"alternative-id":["S0040595720300299"],"URL":"https:\/\/doi.org\/10.1016\/j.therap.2020.02.015","relation":{},"ISSN":["0040-5957"],"issn-type":[{"type":"print","value":"0040-5957"}],"subject":[],"published":{"date-parts":[[2021,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Une lentiginose aggrav\u00e9e par la cap\u00e9citabine","name":"articletitle","label":"Article Title"},{"value":"Therapies","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.therap.2020.02.015","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"simple-article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 Soci\u00e9t\u00e9 fran\u00e7aise de pharmacologie et de th\u00e9rapeutique. Published by Elsevier Masson SAS. All rights reserved.","name":"copyright","label":"Copyright"}]}}