{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,21]],"date-time":"2026-05-21T14:11:22Z","timestamp":1779372682396,"version":"3.53.1"},"reference-count":46,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,7,29]],"date-time":"2025-07-29T00:00:00Z","timestamp":1753747200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Therapies"],"published-print":{"date-parts":[[2026,5]]},"DOI":"10.1016\/j.therap.2025.07.001","type":"journal-article","created":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T06:33:02Z","timestamp":1753857182000},"page":"244-255","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"title":["Safety of SARS-CoV-2 vaccination of pregnant women: Luxembourg's cohort study and literature review"],"prefix":"10.1016","volume":"81","author":[{"given":"Victoria","family":"Ugolini","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0225-3178","authenticated-orcid":false,"given":"Nadine","family":"Petitpain","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Didier","family":"Menzies","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dominique","family":"Swiegot","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Audrey","family":"Fresse","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isabel De La Fuente","family":"Garcia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne-C\u00e9cile","family":"Vuillemin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.therap.2025.07.001_bib0235","doi-asserted-by":"crossref","first-page":"E540","DOI":"10.1503\/cmaj.202604","article-title":"The impact of COVID-19 on pregnancy outcomes: a systematic review and meta-analysis","volume":"193","author":"Wei","year":"2021","journal-title":"CMAJ"},{"key":"10.1016\/j.therap.2025.07.001_bib0240","doi-asserted-by":"crossref","first-page":"1247","DOI":"10.1007\/s40264-021-01131-6","article-title":"COVID-19 vaccination in pregnancy, paediatrics, immunocompromised patients, and persons with history of allergy or prior SARS-CoV-2 infection: overview of current recommendations and pre- and post-marketing evidence for vaccine efficacy and safety","volume":"44","author":"Luxi","year":"2021","journal-title":"Drug Saf"},{"key":"10.1016\/j.therap.2025.07.001_bib0245","doi-asserted-by":"crossref","first-page":"1018","DOI":"10.1002\/pd.5985","article-title":"A reasoned approach towards administering COVID-19 vaccines to pregnant women","volume":"41","author":"Pramanick","year":"2021","journal-title":"Prenat Diagn"},{"key":"10.1016\/j.therap.2025.07.001_bib0250","doi-asserted-by":"crossref","first-page":"2902","DOI":"10.3390\/jcm10132902","article-title":"ISIDOG Consensus Guidelines on COVID-19 vaccination for women before, during and after pregnancy","volume":"10","author":"Donders","year":"2021","journal-title":"JCM"},{"key":"10.1016\/j.therap.2025.07.001_bib0255","series-title":"Un recul suffisant pour confirmer l\u2019importance de se faire vacciner contre la COVID-19 pendant la grossesse","year":"2025"},{"key":"10.1016\/j.therap.2025.07.001_bib0260","series-title":"Recommandation du CSMI concernant la vaccination des femmes enceintes et allaitantes contre la COVID-19","year":"2022"},{"key":"10.1016\/j.therap.2025.07.001_bib0265","series-title":"La division de la pharmacie et des m\u00e9dicaments","year":"2024"},{"key":"10.1016\/j.therap.2025.07.001_bib0270","unstructured":"EMA European Medicine Agency. Guideline on good pharmacovigilance practices (GVP) Module VI\u2013Collection, management and submission of reports of suspected adverse reactions to medicinal products (Rev 2) 2017. https:\/\/www.ema.europa.eu\/en\/human-regulatory-overview\/post-authorisation\/pharmacovigilance-post-authorisation\/good-pharmacovigilance-practices-gvp [Accessed 21 July 2025]."},{"key":"10.1016\/j.therap.2025.07.001_bib0275","series-title":"Timeline human development","year":"2025"},{"key":"10.1016\/j.therap.2025.07.001_bib0280","doi-asserted-by":"crossref","first-page":"2198","DOI":"10.1038\/s41598-023-27935-3","article-title":"Prevalence, predictors, and outcomes of major congenital anomalies: a population-based register study","volume":"13","author":"Al-Dewik","year":"2023","journal-title":"Sci Rep"},{"key":"10.1016\/j.therap.2025.07.001_bib0285","series-title":"Preterm birth","year":"2024"},{"key":"10.1016\/j.therap.2025.07.001_bib0290","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1016\/j.therap.2024.06.003","article-title":"COVACPREG, a French prospective cohort study of women vaccinated against COVID-19 during pregnancy","volume":"80","author":"Lacroix","year":"2025","journal-title":"Therapie"},{"key":"10.1016\/j.therap.2025.07.001_bib0295","unstructured":"Safety of SARS-CoV-2 vaccination during pregnancy (Covid-19)\u2013Collection and analysis of pregnancy course data by the Pharmakovigilanz- und Beratungszentrum f\u00fcr Embryonaltoxikologie - SARS-CoV-2 PregVac. Deutsches Register Klinisches Studien 2024. https:\/\/drks.de\/search\/en\/trial\/DRKS00025255 [Accessed 21 July 2025]."},{"key":"10.1016\/j.therap.2025.07.001_bib0300","doi-asserted-by":"crossref","first-page":"1469","DOI":"10.1001\/jama.2022.3271","article-title":"Association of SARS-CoV-2 vaccination during pregnancy with pregnancy outcomes","volume":"327","author":"Magnus","year":"2022","journal-title":"JAMA"},{"key":"10.1016\/j.therap.2025.07.001_bib0305","doi-asserted-by":"crossref","first-page":"396","DOI":"10.1001\/jama.2023.26945","article-title":"Neonatal outcomes after COVID-19 vaccination in pregnancy","volume":"331","author":"Norman","year":"2024","journal-title":"JAMA"},{"key":"10.1016\/j.therap.2025.07.001_bib0310","unstructured":"ORPHANET. Dysplasie r\u00e9nale. OrphaNet. 2025. https:\/\/www.orpha.net\/fr\/disease\/detail\/93108 [Accessed 21 July 2025]."},{"key":"10.1016\/j.therap.2025.07.001_bib0315","series-title":"Congenital anomalies: epidemiology, types, and patterns","author":"Bacino","year":"2023"},{"key":"10.1016\/j.therap.2025.07.001_bib0320","first-page":"e23294","article-title":"Spontaneous pneumothorax as a late complication of mild COVID-19 infection: a case report","volume":"14","author":"Love","year":"2022","journal-title":"Cureus"},{"key":"10.1016\/j.therap.2025.07.001_bib0325","doi-asserted-by":"crossref","first-page":"1015","DOI":"10.1177\/08850666221091441","article-title":"Incidence and clinical features of pneumomediastinum and pneumothorax in COVID-19 pneumonia","volume":"37","author":"Muhammad","year":"2022","journal-title":"J Intensive Care Med"},{"key":"10.1016\/j.therap.2025.07.001_bib0330","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1038\/s41390-022-02421-0","article-title":"Systematic review and meta-analysis of neonatal outcomes of COVID-19 vaccination in pregnancy","volume":"94","author":"Zhang","year":"2023","journal-title":"Pediatr Res"},{"key":"10.1016\/j.therap.2025.07.001_bib0335","doi-asserted-by":"crossref","first-page":"e2434","DOI":"10.1002\/rmv.2434","article-title":"Effects of COVID-19 vaccination during pregnancy on SARS-CoV-2 infection and maternal and neonatal outcomes: a systematic review and meta-analysis","volume":"33","author":"Rahmati","year":"2023","journal-title":"Rev Med Virol"},{"key":"10.1016\/j.therap.2025.07.001_bib0340","doi-asserted-by":"crossref","first-page":"651","DOI":"10.1002\/ijgo.14336","article-title":"COVID -19 vaccine and pregnancy outcomes: A systematic review and meta-analysis","volume":"159","author":"Carbone","year":"2022","journal-title":"Int J Gynaecol Obstet"},{"key":"10.1016\/j.therap.2025.07.001_bib0345","doi-asserted-by":"crossref","first-page":"2414","DOI":"10.1038\/s41467-022-30052-w","article-title":"Systematic review and meta-analysis of the effectiveness and perinatal outcomes of COVID-19 vaccination in pregnancy","volume":"13","author":"Prasad","year":"2022","journal-title":"Nat Commun"},{"key":"10.1016\/j.therap.2025.07.001_bib0350","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1016\/j.ijid.2023.01.018","article-title":"The dose- and time-dependent effectiveness and safety associated with COVID-19 vaccination during pregnancy: a systematic review and meta-analysis","volume":"128","author":"Wu","year":"2023","journal-title":"Int J Infect Dis"},{"key":"10.1016\/j.therap.2025.07.001_bib0355","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1016\/j.placenta.2024.03.008","article-title":"Effects of SARS-CoV-2 mRNA vaccine on placental histopathology: comparison of a population of uncomplicated COVID-19 positive pregnant women","volume":"149","author":"Tartaglia","year":"2024","journal-title":"Placenta"},{"key":"10.1016\/j.therap.2025.07.001_bib0360","unstructured":"Luxembourg Institute of health, Gouvernement du Grand Duch\u00e9 de Luxembourg, Direction de la Sant\u00e9. Surveillance de la sant\u00e9 p\u00e9rinatale au Luxembourg 2017-2019. Https:\/\/SantePublicLu\/. 2022. https:\/\/sante.public.lu\/fr\/publications\/s\/surveillance-sante-perinatale-2017-2019.html [Accessed 21 July 2025]."},{"key":"10.1016\/j.therap.2025.07.001_bib0365","doi-asserted-by":"crossref","first-page":"1044031","DOI":"10.3389\/fpubh.2023.1044031","article-title":"Associations of COVID-19 vaccination during pregnancy with adverse neonatal and maternal outcomes: a systematic review and meta-analysis","volume":"11","author":"Ding","year":"2023","journal-title":"Front Public Health"},{"key":"10.1016\/j.therap.2025.07.001_bib0370","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1038\/s41541-023-00698-8","article-title":"Maternal and neonatal outcomes of COVID-19 vaccination during pregnancy, a systematic review and meta-analysis","volume":"8","author":"Marchand","year":"2023","journal-title":"NPJ Vaccines"},{"key":"10.1016\/j.therap.2025.07.001_bib0375","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1111\/1471-0528.17721","article-title":"Miscarriage after SARS-CoV-2 vaccination: a population-based cohort study","volume":"131","author":"Velez","year":"2024","journal-title":"BJOG"},{"key":"10.1016\/j.therap.2025.07.001_bib0380","doi-asserted-by":"crossref","first-page":"1629","DOI":"10.1001\/jama.2021.15494","article-title":"Spontaneous abortion following COVID-19 vaccination during pregnancy","volume":"326","author":"Kharbanda","year":"2021","journal-title":"JAMA"},{"key":"10.1016\/j.therap.2025.07.001_bib0385","doi-asserted-by":"crossref","first-page":"e5724","DOI":"10.1002\/pds.5724","article-title":"The risk of miscarriage after COVID -19 vaccination before and during pregnancy","volume":"33","author":"De Feijter","year":"2024","journal-title":"Pharmacoepidemiol Drug Saf"},{"key":"10.1016\/j.therap.2025.07.001_bib0390","series-title":"Enqu\u00eate de pharmacovigilance sur les effets ind\u00e9sirables des vaccins COVID-19 chez les femmes enceintes et allaitantes. Rapport No\u00a07 08\/10\/2020 au 04\/11\/2021","year":"2021"},{"key":"10.1016\/j.therap.2025.07.001_bib0395","first-page":"D6831","article-title":"Self-reported maternal adverse events of covid-19 vaccination during pregnancy","volume":"166","author":"Woestenberg","year":"2022","journal-title":"Ned Tijdschr Geneeskd"},{"key":"10.1016\/j.therap.2025.07.001_bib0400","doi-asserted-by":"crossref","first-page":"1553","DOI":"10.1016\/S1473-3099(22)00426-1","article-title":"Safety of COVID-19 vaccines in pregnancy: a Canadian National Vaccine Safety (CANVAS) network cohort study","volume":"22","author":"Sadarangani","year":"2022","journal-title":"Lancet Infec Dis"},{"key":"10.1016\/j.therap.2025.07.001_bib0405","doi-asserted-by":"crossref","first-page":"1280","DOI":"10.3390\/vaccines11081280","article-title":"Side effects of COVID-19 vaccines in pregnant and lactating mexican women and breastfed infants: A survey-based study","volume":"11","author":"Moll","year":"2023","journal-title":"Vaccines"},{"key":"10.1016\/j.therap.2025.07.001_bib0410","doi-asserted-by":"crossref","first-page":"657","DOI":"10.1007\/s00228-023-03482-8","article-title":"Safety of COVID-19 vaccines in pregnancy: a VAERS based analysis","volume":"79","author":"Santi Laurini","year":"2023","journal-title":"Eur J Clin Pharmacol"},{"key":"10.1016\/j.therap.2025.07.001_bib0415","doi-asserted-by":"crossref","first-page":"627","DOI":"10.1002\/ana.26172","article-title":"COVID-19 vaccine-associated cerebral venous thrombosis in Germany","volume":"90","author":"Schulz","year":"2021","journal-title":"Ann Neurol"},{"key":"10.1016\/j.therap.2025.07.001_bib0420","doi-asserted-by":"crossref","first-page":"2200","DOI":"10.1016\/j.vaccine.2024.01.100","article-title":"COVID-19 vaccines and adverse events of special interest: A multinational Global Vaccine Data Network (GVDN) cohort study of 99 millions vaccinated individuals","volume":"42","author":"Faksova","year":"2024","journal-title":"Vaccine"},{"key":"10.1016\/j.therap.2025.07.001_bib0425","doi-asserted-by":"crossref","first-page":"105906","DOI":"10.1016\/j.jstrokecerebrovasdis.2021.105906","article-title":"Cerebral venous thrombosis after BNT162b2 mRNA SARS-CoV-2 vaccine","volume":"30","author":"Dias","year":"2021","journal-title":"J Stroke Cerebrovasc Dis"},{"key":"10.1016\/j.therap.2025.07.001_bib0430","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1007\/s10072-021-05714-0","article-title":"Cerebral venous sinus thrombosis after mRNA-based COVID-19 vaccination","volume":"43","author":"Yagi","year":"2022","journal-title":"Neurol Sci"},{"key":"10.1016\/j.therap.2025.07.001_bib0435","doi-asserted-by":"crossref","first-page":"e1","DOI":"10.1097\/AOG.0000000000002706","article-title":"ACOG Practice Bulletin No.196: thromboembolism in pregnancy","volume":"132","year":"2018","journal-title":"Obstet Gynecol"},{"key":"10.1016\/j.therap.2025.07.001_bib0440","doi-asserted-by":"crossref","first-page":"1287","DOI":"10.1007\/s10741-020-10061-x","article-title":"Peripartum cardiomyopathy: a review","volume":"26","author":"Iorgoveanu","year":"2021","journal-title":"Heart Fail Rev"},{"key":"10.1016\/j.therap.2025.07.001_bib0445","doi-asserted-by":"crossref","first-page":"605","DOI":"10.1002\/cpt.2499","article-title":"Features of inflammatory heart reactions following mRNA COVID-19 vaccination at a global level","volume":"111","author":"Chouchana","year":"2022","journal-title":"Clin Pharmacol Ther"},{"key":"10.1016\/j.therap.2025.07.001_bib0450","doi-asserted-by":"crossref","first-page":"3688","DOI":"10.1016\/j.vaccine.2023.03.038","article-title":"Safety of COVID-19 vaccines during pregnancy: a systematic review and meta-analysis","volume":"41","author":"Ciapponi","year":"2023","journal-title":"Vaccine"},{"key":"10.1016\/j.therap.2025.07.001_bib0455","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1016\/S0895-4356(99)00167-5","article-title":"Influence of question structure on the recall of self-reported drug use","volume":"53","author":"Klungel","year":"2000","journal-title":"J Clin Epidemiol"},{"key":"10.1016\/j.therap.2025.07.001_bib0460","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1016\/j.therap.2018.11.014","article-title":"Pharmacoepidemiology in pregnancy","volume":"74","author":"Benevent","year":"2019","journal-title":"Therapie"}],"container-title":["Therapies"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0040595725001039?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0040595725001039?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,5,21]],"date-time":"2026-05-21T13:36:35Z","timestamp":1779370595000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0040595725001039"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,5]]},"references-count":46,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2026,5]]}},"alternative-id":["S0040595725001039"],"URL":"https:\/\/doi.org\/10.1016\/j.therap.2025.07.001","relation":{},"ISSN":["0040-5957"],"issn-type":[{"value":"0040-5957","type":"print"}],"subject":[],"published":{"date-parts":[[2026,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Safety of SARS-CoV-2 vaccination of pregnant women: Luxembourg's cohort study and literature review","name":"articletitle","label":"Article Title"},{"value":"Therapies","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.therap.2025.07.001","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Author(s). Published by Elsevier Masson SAS on behalf of Soci\u00e9t\u00e9 fran\u00e7aise de pharmacologie et de th\u00e9rapeutique.","name":"copyright","label":"Copyright"}]}}