{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,26]],"date-time":"2026-02-26T11:32:29Z","timestamp":1772105549516,"version":"3.50.1"},"reference-count":23,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2004,1,1]],"date-time":"2004-01-01T00:00:00Z","timestamp":1072915200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Thrombosis Research"],"published-print":{"date-parts":[[2004]]},"DOI":"10.1016\/j.thromres.2004.06.007","type":"journal-article","created":{"date-parts":[[2004,7,23]],"date-time":"2004-07-23T14:54:10Z","timestamp":1090594450000},"page":"213-220","source":"Crossref","is-referenced-by-count":39,"title":["An onion variety has natural antithrombotic effect as assessed by thrombosis\/thrombolysis models in rodents"],"prefix":"10.1016","volume":"114","author":[{"given":"Kaori","family":"Yamada","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aki","family":"Naemura","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Naoko","family":"Sawashita","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuji","family":"Noguchi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Junichiro","family":"Yamamoto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.thromres.2004.06.007_BIB1","doi-asserted-by":"crossref","first-page":"1113","DOI":"10.1001\/jama.1995.03520380049034","article-title":"Protective effect of fruits and vegetables on development of stroke in men","volume":"273","author":"Gillman","year":"1995","journal-title":"JAMA"},{"key":"10.1016\/j.thromres.2004.06.007_BIB2","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1093\/ajcn\/76.1.93","article-title":"Fruit and vegetable intake and risk of cardiovascular disease in US adults: the first national health and nutrition examination survey epidemiologic follow-up study","volume":"76","author":"Bazzano","year":"2002","journal-title":"Am. J. Clin. Nutr."},{"key":"10.1016\/j.thromres.2004.06.007_BIB3","doi-asserted-by":"crossref","first-page":"1031","DOI":"10.1079\/BJN2003994","article-title":"Tomatoes have natural anti-thrombotic effects","volume":"90","author":"Yamamoto","year":"2003","journal-title":"Br. J. Nutr."},{"key":"10.1016\/j.thromres.2004.06.007_BIB4","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1056\/NEJM199201233260406","article-title":"The pathogenesis of coronary artery disease and the acute coronary syndromes","volume":"326","author":"Fuster","year":"1992","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.thromres.2004.06.007_BIB5","series-title":"Haemostasis and thrombosis","first-page":"259","article-title":"Interaction of blood platelets with the vessel wall","author":"Sixma","year":"1994"},{"key":"10.1016\/j.thromres.2004.06.007_BIB6","first-page":"43","article-title":"Modeling coronary thrombosis from non-anticoagulated human blood in vitro","volume":"4","author":"Gorog","year":"1990","journal-title":"Hematol. Pathol."},{"key":"10.1016\/j.thromres.2004.06.007_BIB7","doi-asserted-by":"crossref","first-page":"1077","DOI":"10.1161\/01.CIR.85.3.1077","article-title":"High-dose aspirin inhibits shear-induced platelet reaction involving thrombin generation","volume":"85","author":"Ratnatunga","year":"1992","journal-title":"Circulation"},{"key":"10.1016\/j.thromres.2004.06.007_BIB8","doi-asserted-by":"crossref","first-page":"514","DOI":"10.1055\/s-0038-1653806","article-title":"Thrombotic Status Analyzer. Measurement of platelet-rich thrombus formation and lysis in native blood","volume":"73","author":"Gorog","year":"1995","journal-title":"Thromb. Haemost."},{"key":"10.1016\/j.thromres.2004.06.007_BIB9","doi-asserted-by":"crossref","first-page":"781","DOI":"10.1097\/00001721-200312000-00016","article-title":"Impaired spontaneous thrombolytic activity in elderly and in habitual smokers, as measured by a new global thrombosis test","volume":"14","author":"Ikarugi","year":"2003","journal-title":"Blood Coagul. Fibrinolysis"},{"key":"10.1016\/j.thromres.2004.06.007_BIB10","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1097\/00001721-200301000-00007","article-title":"Gorog Thrombosis Test: a global in vitro test of platelet function and thrombolysis","volume":"14","author":"Yamamoto","year":"2003","journal-title":"Blood Coagul. Fibrinolysis"},{"key":"10.1016\/j.thromres.2004.06.007_BIB11","doi-asserted-by":"crossref","first-page":"697","DOI":"10.1097\/00001721-200312000-00001","article-title":"Review: Shear-induced in-vitro haemostasis\/thrombosis tests: the benefit of using native blood","volume":"14","author":"Yamamoto","year":"2003","journal-title":"Blood Coagul. Fibrinolysis"},{"key":"10.1016\/j.thromres.2004.06.007_BIB12","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1097\/00001721-200209000-00004","article-title":"A new model to evaluate the diet-induced prothrombotic state, using He\u2013Ne laser-induced thrombogenesis in the carotid artery of apolipoprotein receptor E-deficient and low-density lipoprotein receptor-deficient mice","volume":"13","author":"Ijiri","year":"2002","journal-title":"Blood Coagul. Fibrinolysis"},{"key":"10.1016\/j.thromres.2004.06.007_BIB13","doi-asserted-by":"crossref","first-page":"100","DOI":"10.3136\/nskkk.42.100","article-title":"Isolation of flavonoid-glycosides in onion and identification by chemical synthesis of the glycosides","volume":"42","author":"Tsushida","year":"1995","journal-title":"Nippon Shokuhin Kagaku Kaishi"},{"key":"10.1016\/j.thromres.2004.06.007_BIB14","doi-asserted-by":"crossref","first-page":"1583","DOI":"10.1056\/NEJMoa011090","article-title":"Simvastatin and niacin, antioxidant vitamins, or the combination for the prevention of coronary disease","volume":"345","author":"Brown","year":"2001","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.thromres.2004.06.007_BIB15","unstructured":"Sawashita N. Effect of protein and peptide on thrombotic tendency. Master's thesis, Kobe Gakuin University, 2003, pp. 42\u201354."},{"key":"10.1016\/j.thromres.2004.06.007_BIB16","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1093\/jn\/130.1.34","article-title":"Chronic consumption of raw but not boiled Welsh onion juice inhibits rat platelet function","volume":"130","author":"Chen","year":"2000","journal-title":"J. Nutr."},{"key":"10.1016\/j.thromres.2004.06.007_BIB17","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1054\/plef.1998.0006","article-title":"Effect of raw versus boiled aqueous extract of garlic and onion on platelet aggregation","volume":"60","author":"Ali","year":"1999","journal-title":"Prostaglandins Leukot. Essent. Fatty Acids"},{"key":"10.1016\/j.thromres.2004.06.007_BIB18","doi-asserted-by":"crossref","first-page":"478","DOI":"10.1136\/bmj.312.7029.478","article-title":"Flavonoid intake and coronary mortality in Finland: a cohort study","volume":"312","author":"Knekt","year":"1996","journal-title":"Br. Med. J."},{"key":"10.1016\/j.thromres.2004.06.007_BIB19","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1001\/archinte.1995.00430040053006","article-title":"Flavonoid intake and long-term risk of coronary heart disease and cancer in the seven countries study","volume":"155","author":"Hertog","year":"1995","journal-title":"Arch. Int. Med."},{"key":"10.1016\/j.thromres.2004.06.007_BIB20","doi-asserted-by":"crossref","first-page":"1061","DOI":"10.1016\/0278-6915(95)00077-1","article-title":"Review of the biology of quercetin and related bioflavonoids","volume":"33","author":"Formica","year":"1995","journal-title":"Food Chem. Toxicol."},{"key":"10.1016\/j.thromres.2004.06.007_BIB21","doi-asserted-by":"crossref","first-page":"1079","DOI":"10.1046\/j.1538-7836.2003.00212.x","article-title":"Quercetin inhibits collagen-stimulated platelet activation through inhibition of multiple components of the glycoprotein VI signaling pathway","author":"Hubbard","year":"2003","journal-title":"J. Thromb. Haemost."},{"key":"10.1016\/j.thromres.2004.06.007_BIB22","doi-asserted-by":"crossref","first-page":"4961","DOI":"10.1073\/pnas.77.8.4961","article-title":"Fecalase: a model for activation of dietary glycosides to mutagens by intestinal flora","volume":"77","author":"Tamura","year":"1980","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.thromres.2004.06.007_BIB23","doi-asserted-by":"crossref","first-page":"1324","DOI":"10.1271\/bbb.58.1324","article-title":"Malonylated anthocyanins from bulbs of red onion, Allium cepa L.","volume":"58","author":"Terahara","year":"1994","journal-title":"Biosci. Biotechnol. Biochem."}],"container-title":["Thrombosis Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0049384804003160?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0049384804003160?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2020,4,2]],"date-time":"2020-04-02T20:56:13Z","timestamp":1585860973000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0049384804003160"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004]]},"references-count":23,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2004]]}},"alternative-id":["S0049384804003160"],"URL":"https:\/\/doi.org\/10.1016\/j.thromres.2004.06.007","relation":{},"ISSN":["0049-3848"],"issn-type":[{"value":"0049-3848","type":"print"}],"subject":[],"published":{"date-parts":[[2004]]}}}