{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T01:43:14Z","timestamp":1791423794274,"version":"4.3.3"},"reference-count":29,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2005,1,1]],"date-time":"2005-01-01T00:00:00Z","timestamp":1104537600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Thrombosis Research"],"published-print":{"date-parts":[[2005,1]]},"DOI":"10.1016\/j.thromres.2004.11.022","type":"journal-article","created":{"date-parts":[[2004,12,30]],"date-time":"2004-12-30T12:22:15Z","timestamp":1104409335000},"page":"133-137","source":"Crossref","is-referenced-by-count":13,"title":["Role of thrombophilic risk factors in children with non-stroke cerebral palsy"],"prefix":"10.1016","volume":"116","author":[{"given":"Aviva","family":"Fattal-Valevski","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gili","family":"Kenet","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael J.","family":"Kupferminc","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ronit","family":"Mesterman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yael","family":"Leitner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eli","family":"Rimon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shaul","family":"Harel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Avi","family":"Hassner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.thromres.2004.11.022_bib1","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1111\/j.1469-8749.1992.tb11479.x","article-title":"Cerebral palsy epidemiology: where are we now and where are we going?","volume":"34","author":"Mutch","year":"1992","journal-title":"Dev. Med. Child Neurol."},{"key":"10.1016\/j.thromres.2004.11.022_bib2","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1097\/00008480-199912000-00002","article-title":"Causes of cerebral palsy","volume":"11","author":"Nelson","year":"1999","journal-title":"Curr. Opin. Pediatr."},{"key":"10.1016\/j.thromres.2004.11.022_bib3","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1097\/00002060-200204000-00011","article-title":"Risk factors of cerebral palsy in preterm infants","volume":"81","author":"Han","year":"2002","journal-title":"Am. J. Phys. Med. Rehabil."},{"key":"10.1016\/j.thromres.2004.11.022_bib4","doi-asserted-by":"crossref","first-page":"665","DOI":"10.1002\/ana.410440413","article-title":"Neonatal cytokines and coagulation factors in children","volume":"44","author":"Nelson","year":"1998","journal-title":"Ann. Neurol."},{"key":"10.1016\/j.thromres.2004.11.022_bib5","doi-asserted-by":"crossref","first-page":"1549","DOI":"10.1136\/bmj.317.7172.1549","article-title":"Antepartum risk factors for newborn encephalopathy: the Western Australian case control study","volume":"317","author":"Badawi","year":"1998","journal-title":"Br. Med. J."},{"key":"10.1016\/j.thromres.2004.11.022_bib6","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1002\/mrdd.10037","article-title":"The epidemiology of cerebral palsy in term infants","volume":"8","author":"Nelson","year":"2002","journal-title":"Ment. Retard. Dev. Disabil. Res. Rev."},{"key":"10.1016\/j.thromres.2004.11.022_bib7","doi-asserted-by":"crossref","first-page":"724","DOI":"10.1017\/S0012162201001323","article-title":"Is thrombophilia a factor in the development of hemiplegic cerebral palsy?","volume":"43","author":"Smith","year":"2001","journal-title":"Dev. Med. Child Neurol."},{"key":"10.1016\/j.thromres.2004.11.022_bib8","doi-asserted-by":"crossref","first-page":"967","DOI":"10.1001\/archneur.56.8.967","article-title":"Prethrombotic disorders in children with ischemic stroke and sinovenous thrombosis","volume":"56","author":"Bonduel","year":"1999","journal-title":"Arch. Neurol."},{"key":"10.1016\/j.thromres.2004.11.022_bib9","doi-asserted-by":"crossref","first-page":"676","DOI":"10.1067\/mpd.2001.118192","article-title":"Venous thromboembolism in childhood: a prospective two-year registry in The Netherlands","volume":"139","author":"van Ommen","year":"2001","journal-title":"J. Pediatr."},{"key":"10.1016\/j.thromres.2004.11.022_bib10","first-page":"227","article-title":"Pediatric thromboembolism; the influence of non-genetic factors and the role of activated protein C resistance and protein C deficiency","volume":"156","author":"Uttenreuther-Fischer","year":"1996","journal-title":"Eur. J. Pediatr."},{"key":"10.1016\/j.thromres.2004.11.022_bib11","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1056\/NEJM200108093450604","article-title":"Cerebral sinovenous thrombosis in children","volume":"345","author":"De-Veber","year":"2001","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.thromres.2004.11.022_bib12","doi-asserted-by":"crossref","first-page":"1540","DOI":"10.1016\/S0140-6736(02)11520-0","article-title":"Prospective assessment of risk factors for recurrent stroke during childhood\u2014a 5-year follow-up study","volume":"360","author":"Strater","year":"2002","journal-title":"Lancet"},{"key":"10.1016\/j.thromres.2004.11.022_bib13","doi-asserted-by":"crossref","first-page":"1283","DOI":"10.1161\/01.STR.31.6.1283","article-title":"Factor V Leiden and antiphospholipid antibodies are significant risk factors for ischemic stroke in children","volume":"31","author":"Kenet","year":"2000","journal-title":"Stroke"},{"key":"10.1016\/j.thromres.2004.11.022_bib14","doi-asserted-by":"crossref","first-page":"2437","DOI":"10.1161\/01.STR.31.10.2437","article-title":"Symptomatic ischemic stroke in full-term neonates: role of acquired and genetic prothrombotic risk factors","volume":"31","author":"Gunther","year":"2000","journal-title":"Stroke"},{"key":"10.1016\/j.thromres.2004.11.022_bib15","doi-asserted-by":"crossref","first-page":"777","DOI":"10.1017\/S0012162299001541","article-title":"Homozygous factor-V mutation as a genetic cause of perinatal thrombosis and cerebral palsy","volume":"41","author":"Harum","year":"1999","journal-title":"Dev. Med. Child Neurol."},{"key":"10.1016\/j.thromres.2004.11.022_bib16","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1002\/ana.20184","article-title":"The factor V G1691A mutation is a risk for porencephaly: a case-control study","volume":"56","author":"Debus","year":"2004","journal-title":"Ann. Neurol."},{"key":"10.1016\/j.thromres.2004.11.022_bib17","doi-asserted-by":"crossref","first-page":"787","DOI":"10.1136\/jmg.37.10.787","article-title":"Hemiplegic cerebral palsy and the factor V Leiden mutation","volume":"37","author":"Halliday","year":"2000","journal-title":"J. Med. Genet."},{"key":"10.1016\/j.thromres.2004.11.022_bib18","doi-asserted-by":"crossref","first-page":"372","DOI":"10.1002\/ana.410420316","article-title":"Factor V Leiden mutation: an unrecognized cause of hemiplegic cerebral palsy, neonatal stroke and placental thrombosis","volume":"42","author":"Thorarensen","year":"1997","journal-title":"Ann. Neurol."},{"key":"10.1016\/j.thromres.2004.11.022_bib19","doi-asserted-by":"crossref","first-page":"735","DOI":"10.1177\/088307380101601006","article-title":"Cerebrovascular disorders in children with the factor V Leiden mutation","volume":"16","author":"Lynch","year":"2001","journal-title":"J. Child Neurol."},{"key":"10.1016\/j.thromres.2004.11.022_bib20","doi-asserted-by":"crossref","first-page":"643","DOI":"10.1203\/00006450-200105000-00006","article-title":"Increased risk of intraventricular hemorrhage in preterm infants with thrombophilia","volume":"49","author":"Petaja","year":"2001","journal-title":"Pediatr. Res."},{"key":"10.1016\/j.thromres.2004.11.022_bib21","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1111\/j.1651-2227.2002.tb02910.x","article-title":"Prothrombotic factors in neonates with cerebral thrombosis and intraventricular hemorrhage","volume":"91","author":"Aronis","year":"2002","journal-title":"Acta Paediatr., Suppl."},{"key":"10.1016\/j.thromres.2004.11.022_bib22","doi-asserted-by":"crossref","first-page":"823","DOI":"10.1160\/TH03-02-0089","article-title":"Thrombophilia does not increase risk for neonatal complications in preterm infants","volume":"90","author":"Kenet","year":"2003","journal-title":"Thromb. Haemost."},{"key":"10.1016\/j.thromres.2004.11.022_bib23","doi-asserted-by":"crossref","first-page":"1222","DOI":"10.1056\/NEJM200104193441607","article-title":"Genetic susceptibility to venous thrombosis","volume":"344","author":"Seligsohn","year":"2001","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.thromres.2004.11.022_bib24","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1038\/369064a0","article-title":"Mutation in blood coagulation factor V associated with resistance to activated protein C","volume":"369","author":"Bertina","year":"1994","journal-title":"Nature"},{"key":"10.1016\/j.thromres.2004.11.022_bib25","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1038\/ng0595-111","article-title":"A candidate genetic risk factor for vascular disease: a common mutation in methylene-tetrahydrofolate reductase","volume":"10","author":"Frosst","year":"1995","journal-title":"Nat. Genet."},{"key":"10.1016\/j.thromres.2004.11.022_bib26","doi-asserted-by":"crossref","first-page":"3698","DOI":"10.1182\/blood.V88.10.3698.bloodjournal88103698","article-title":"A genetic variation in the 3\u2032-untranslated region of the prothrombin gene is associated with elevated plasma prothrombin levels and an increase in venous thrombosis","volume":"88","author":"Poort","year":"1996","journal-title":"Blood"},{"key":"10.1016\/j.thromres.2004.11.022_bib27","series-title":"Neurobiology of the newborn","first-page":"217","author":"Volpe","year":"2001"},{"key":"10.1016\/j.thromres.2004.11.022_bib28","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1055\/s-0038-1642667","article-title":"New molecular insights of thrombophilia: resistance to activated protein C caused by Arg506 to Gln. Mutation in factor V as pathogenetic risk factor for venous thrombosis","volume":"74","author":"Dalback","year":"1995","journal-title":"Thromb. Haemost."},{"key":"10.1016\/j.thromres.2004.11.022_bib29","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1161\/01.ATV.19.3.511","article-title":"Single and combined prothrombotic factors in patients with idiopathic venous thromboembolism","volume":"19","author":"Salomon","year":"1999","journal-title":"Arterioscler. Thromb. Vasc. Biol."}],"container-title":["Thrombosis Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0049384804006267?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0049384804006267?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2020,4,5]],"date-time":"2020-04-05T02:28:20Z","timestamp":1586053700000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0049384804006267"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,1]]},"references-count":29,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2005,1]]}},"alternative-id":["S0049384804006267"],"URL":"https:\/\/doi.org\/10.1016\/j.thromres.2004.11.022","relation":{},"ISSN":["0049-3848"],"issn-type":[{"value":"0049-3848","type":"print"}],"subject":[],"published":{"date-parts":[[2005,1]]}}}