{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,11]],"date-time":"2025-11-11T12:44:24Z","timestamp":1762865064834},"reference-count":28,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2006,1,1]],"date-time":"2006-01-01T00:00:00Z","timestamp":1136073600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Thrombosis Research"],"published-print":{"date-parts":[[2006,1]]},"DOI":"10.1016\/j.thromres.2005.11.015","type":"journal-article","created":{"date-parts":[[2006,1,11]],"date-time":"2006-01-11T14:36:36Z","timestamp":1136990196000},"page":"755-762","source":"Crossref","is-referenced-by-count":18,"title":["Arterial antithrombotic effects of aspirin, heparin, enoxaparin and clopidogrel alone, or in combination, in the rat"],"prefix":"10.1016","volume":"118","author":[{"given":"Heather J.","family":"Daykin","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sharelle A.","family":"Sturgeon","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Catherine","family":"Jones","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christine E.","family":"Wright","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.thromres.2005.11.015_bib1","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1097\/00019501-199504000-00012","article-title":"Two-pronged antiplatelet therapy with aspirin and ticlopidine without systemic anticoagulation: an alternative therapeutic strategy after bailout stent implantation","volume":"6","author":"Van Belle","year":"1995","journal-title":"Coron Artery Dis"},{"key":"10.1016\/j.thromres.2005.11.015_bib2","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1002\/ccd.1810350102","article-title":"Intracoronary stenting without coumadin: one month results of a French multicenter study","volume":"35","author":"Morice","year":"1995","journal-title":"Cathet Cardiovasc Diagn"},{"key":"10.1016\/j.thromres.2005.11.015_bib3","doi-asserted-by":"crossref","first-page":"512","DOI":"10.1055\/s-0037-1615238","article-title":"The antiaggregating and antithrombotic activity of clopidogrel is potentiated by aspirin in several experimental models in the rabbit","volume":"80","author":"Herbert","year":"1998","journal-title":"Thromb Haemost"},{"key":"10.1016\/j.thromres.2005.11.015_bib4","doi-asserted-by":"crossref","first-page":"811","DOI":"10.1001\/jama.276.10.811","article-title":"Adding heparin to aspirin reduces the incidence of myocardial infarction and death in patients with unstable angina. A meta-analysis","volume":"276","author":"Oler","year":"1996","journal-title":"JAMA"},{"key":"10.1016\/j.thromres.2005.11.015_bib5","doi-asserted-by":"crossref","first-page":"681","DOI":"10.1161\/01.CIR.97.7.681","article-title":"Dissolution of mural thrombus by specific thrombin inhibition with r-hirudin: comparison with heparin and aspirin","volume":"97","author":"Meyer","year":"1998","journal-title":"Circulation"},{"key":"10.1016\/j.thromres.2005.11.015_bib6","doi-asserted-by":"crossref","unstructured":"Sturgeon SA, Jones C, Angus JA, Wright CE. Adaptation of the Folts and electrolytic methods of arterial thrombosis for the study of anti-thrombotic molecules in small animals. J Pharmacol Toxicol Methods in press. doi:10.1016\/j.vascn.2005.06.006.","DOI":"10.1016\/j.vascn.2005.06.006"},{"key":"10.1016\/j.thromres.2005.11.015_bib7","first-page":"370","article-title":"Experimental arterial platelet thrombosis, platelet inhibitors, and their possible clinical relevance","volume":"3","author":"Folts","year":"1982","journal-title":"Cardiovasc Rev Rep"},{"key":"10.1016\/j.thromres.2005.11.015_bib8","first-page":"IV-3","article-title":"An in vivo model of experimental arterial stenosis, intimal damage, and periodic thrombosis","volume":"83","author":"Folts","year":"1991","journal-title":"Circulation"},{"key":"10.1016\/j.thromres.2005.11.015_bib9","first-page":"155","article-title":"Incomplete reversal of enoxaparin-induced bleeding by protamine sulfate","volume":"21","author":"Bang","year":"1991","journal-title":"Haemostasis"},{"key":"10.1016\/j.thromres.2005.11.015_bib10","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1093\/cvr\/28.3.303","article-title":"Repeated measurements and multiple comparisons in cardiovascular research","volume":"28","author":"Ludbrook","year":"1994","journal-title":"Cardiovasc Res"},{"key":"10.1016\/j.thromres.2005.11.015_bib11","doi-asserted-by":"crossref","first-page":"663","DOI":"10.1016\/0049-3848(80)90369-2","article-title":"Antithrombotic effects of ticlopidine, acetylsalicyclic acid and dipyridamole in vascular shunt model in rats","volume":"17","author":"Ashida","year":"1980","journal-title":"Thromb Res"},{"key":"10.1016\/j.thromres.2005.11.015_bib12","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/0049-3848(87)90340-9","article-title":"Electrically induced arterial thrombosis model in the conscious rat","volume":"48","author":"Massad","year":"1987","journal-title":"Thromb Res"},{"key":"10.1016\/j.thromres.2005.11.015_bib13","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1055\/s-0038-1651642","article-title":"Effects of antithrombotic drugs in a rat model of aspirin-insensitive arterial thrombosis","volume":"69","author":"Schumacher","year":"1993","journal-title":"Thromb Haemost"},{"key":"10.1016\/j.thromres.2005.11.015_bib14","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1016\/S0014-2999(97)83044-0","article-title":"Antithrombotic effects in a rat model of aspirin-insensitive arterial thrombosis of desethyl KBT-3022, the main active metabolite of a new antiplatelet agent, KBT-3022","volume":"328","author":"Shimazawa","year":"1997","journal-title":"Eur J Pharmacol"},{"key":"10.1016\/j.thromres.2005.11.015_bib15","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/1056-8719(95)00099-2","article-title":"A ferret model of electrical-induction of arterial thrombosis that is sensitive to aspirin","volume":"35","author":"Schumacher","year":"1996","journal-title":"J Pharmacol Toxicol Methods"},{"key":"10.1016\/j.thromres.2005.11.015_bib16","first-page":"219","article-title":"Comparison of a thromboxane receptor antagonist and aspirin in experimental arterial thrombosis","volume":"23","author":"Schumacher","year":"1993","journal-title":"Haemostasis"},{"key":"10.1016\/j.thromres.2005.11.015_bib17","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1055\/s-0038-1651643","article-title":"Experimental thrombosis on a collagen coated arterioarterial shunt in rats: a pharmacological model to study antithrombotic agents inhibiting thrombin formation and platelet deposition","volume":"69","author":"Freund","year":"1993","journal-title":"Thromb Haemost"},{"key":"10.1016\/j.thromres.2005.11.015_bib18","first-page":"H1787","article-title":"Analysis of shear stress and hemodynamic factors in a model of coronary artery stenosis and thrombosis","volume":"265","author":"Strony","year":"1993","journal-title":"Am J Physiol"},{"key":"10.1016\/j.thromres.2005.11.015_bib19","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1016\/0006-2952(92)90445-O","article-title":"Importance of hepatic metabolism in the antiaggregating activity of the thienopyridine clopidogrel","volume":"44","author":"Savi","year":"1992","journal-title":"Biochem Pharmacol"},{"key":"10.1016\/j.thromres.2005.11.015_bib20","doi-asserted-by":"crossref","first-page":"394","DOI":"10.7326\/0003-4819-129-5-199809010-00009","article-title":"The antiplatelet effects of ticlopidine and clopidogrel","volume":"129","author":"Sharis","year":"1998","journal-title":"Ann Intern Med"},{"key":"10.1016\/j.thromres.2005.11.015_bib21","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1055\/s-0038-1653690","article-title":"Experimental thrombosis in rats with continuous registration","volume":"26","author":"Hladovec","year":"1974","journal-title":"Thromb Diath Haemorrh"},{"key":"10.1016\/j.thromres.2005.11.015_bib22","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1002\/micr.10048","article-title":"Local heparin is superior to systemic heparin in preventing arterial thrombosis","volume":"22","author":"Andresen","year":"2002","journal-title":"Microsurgery"},{"key":"10.1016\/j.thromres.2005.11.015_bib23","first-page":"282","article-title":"Comparison of antithrombotic activity of heparin, ASA, sulfinpyrazone and VK 744 in a rat model of arterial thrombosis","volume":"7","author":"Philp","year":"1978","journal-title":"Haemostasis"},{"issue":"1","key":"10.1016\/j.thromres.2005.11.015_bib24","first-page":"57","article-title":"Interaction of heparinoids with platelets: comparison with heparin and low molecular weight heparins","volume":"17","author":"Messmore","year":"1991","journal-title":"Semin Thromb Hemost"},{"key":"10.1016\/j.thromres.2005.11.015_bib25","doi-asserted-by":"crossref","first-page":"993","DOI":"10.1124\/jpet.102.040089","article-title":"Nonpeptide factor Xa inhibitors: III. Effects of DPC423, an orally-active pyrazole antithrombotic agent, on arterial thrombosis in rabbits","volume":"303","author":"Wong","year":"2002","journal-title":"J Pharmacol Exp Ther"},{"key":"10.1016\/j.thromres.2005.11.015_bib26","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1016\/S0049-3848(00)00299-1","article-title":"Comparing the antithrombotic efficacy of a humanized anti-factor IX(a) monoclonal antibody (SB 249417) to the low molecular weight heparin enoxaparin in a rat model of arterial thrombosis","volume":"100","author":"Toomey","year":"2000","journal-title":"Thromb Res"},{"key":"10.1016\/j.thromres.2005.11.015_bib27","doi-asserted-by":"crossref","first-page":"489S","DOI":"10.1378\/chest.114.5_Supplement.489S","article-title":"Heparin and low-molecular-weight heparin: mechanisms of action, pharmacokinetics, dosing considerations, monitoring, efficacy, and safety","volume":"114","author":"Hirsh","year":"1998","journal-title":"Chest"},{"key":"10.1016\/j.thromres.2005.11.015_bib28","doi-asserted-by":"crossref","first-page":"908","DOI":"10.1161\/01.ATV.18.6.908","article-title":"Inhibition of repetitive thrombus formation in the stenosed canine coronary artery by enoxaparin, but not by unfractionated heparin","volume":"18","author":"Leadley","year":"1998","journal-title":"Arterioscler Thromb Vasc Biol"}],"container-title":["Thrombosis Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0049384805004524?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0049384805004524?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,4,14]],"date-time":"2019-04-14T09:03:17Z","timestamp":1555232597000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0049384805004524"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,1]]},"references-count":28,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2006,1]]}},"alternative-id":["S0049384805004524"],"URL":"https:\/\/doi.org\/10.1016\/j.thromres.2005.11.015","relation":{},"ISSN":["0049-3848"],"issn-type":[{"value":"0049-3848","type":"print"}],"subject":[],"published":{"date-parts":[[2006,1]]}}}