{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,23]],"date-time":"2026-04-23T03:00:20Z","timestamp":1776913220719,"version":"3.51.2"},"reference-count":43,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2006,1,1]],"date-time":"2006-01-01T00:00:00Z","timestamp":1136073600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Thrombosis Research"],"published-print":{"date-parts":[[2006,1]]},"DOI":"10.1016\/j.thromres.2005.12.011","type":"journal-article","created":{"date-parts":[[2006,2,16]],"date-time":"2006-02-16T07:21:15Z","timestamp":1140074475000},"page":"733-739","source":"Crossref","is-referenced-by-count":34,"title":["Aqueous extracts of Ocimum basilicum L. (sweet basil) decrease platelet aggregation induced by ADP and thrombin in vitro and rats arterio\u2013venous shunt thrombosis in vivo"],"prefix":"10.1016","volume":"118","author":[{"given":"Ibadet","family":"Tohti","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maynur","family":"Tursun","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anwar","family":"Umar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Subat","family":"Turdi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Horyat","family":"Imin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nicholas","family":"Moore","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"4","key":"10.1016\/j.thromres.2005.12.011_bib1","doi-asserted-by":"crossref","first-page":"483","DOI":"10.2515\/therapie:2004083","article-title":"Uighur traditional medicine syndrome of Abnormal Savda in men is associated with oxidative stress, which can be improved by Munziq and Mushil of Abnormal Savda","volume":"59","author":"Upur","year":"2004","journal-title":"Therapie"},{"issue":"9","key":"10.1016\/j.thromres.2005.12.011_bib2","first-page":"406","article-title":"Randomized placebo-controlled, single blind trial of holy basil leaves in patients with noninsulin-dependent diabetes mellitus","volume":"34","author":"Agrawal","year":"1996","journal-title":"Int J Clin Pharmacol Ther"},{"issue":"1","key":"10.1016\/j.thromres.2005.12.011_bib3","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1016\/S0378-8741(01)00374-9","article-title":"Evaluation of anti-hyperglycemic and hypoglycemic effect of Trigonella foenum-graecum Linn, Ocimum sanctum Linn and Pterocarpus marsupium Linn in normal and alloxanized diabetic rats","volume":"79","author":"Vats","year":"2002","journal-title":"J Ethnopharmacol"},{"issue":"4","key":"10.1016\/j.thromres.2005.12.011_bib4","doi-asserted-by":"crossref","first-page":"444","DOI":"10.1016\/S0367-326X(00)00143-X","article-title":"Hypoglycaemic activity of Ocimum gratissimum in rats","volume":"71","author":"Aguiyi","year":"2000","journal-title":"Fitoterapia"},{"issue":"2","key":"10.1016\/j.thromres.2005.12.011_bib5","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1016\/j.fitote.2004.12.009","article-title":"Antibacterial properties of essential oils from Thai medicinal plants","volume":"76","author":"Wannissorn","year":"2005","journal-title":"Fitoterapia"},{"issue":"11","key":"10.1016\/j.thromres.2005.12.011_bib6","doi-asserted-by":"crossref","first-page":"1876","DOI":"10.1086\/430003","article-title":"Effective treatment of experimental acute otitis media by application of volatile fluids into the ear canal","volume":"191","author":"Kristinsson","year":"2005","journal-title":"J Infect Dis"},{"issue":"11","key":"10.1016\/j.thromres.2005.12.011_bib7","doi-asserted-by":"crossref","first-page":"3486","DOI":"10.1021\/jf035145e","article-title":"Composition and functional properties of the essential oil of Amazonian basil, Ocimum micranthum Willd., Labiatae in comparison with commercial essential oils","volume":"52","author":"Sacchetti","year":"2004","journal-title":"J Agric Food Chem"},{"issue":"22","key":"10.1016\/j.thromres.2005.12.011_bib8","doi-asserted-by":"crossref","first-page":"6824","DOI":"10.1021\/jf040043p","article-title":"Effect of essential oils on the growth of Fusarium verticillioides and Fumonisin contamination in corn","volume":"52","author":"Fandohan","year":"2004","journal-title":"J Agric Food Chem"},{"issue":"5","key":"10.1016\/j.thromres.2005.12.011_bib9","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1111\/j.1472-765X.2004.01587.x","article-title":"Five essential oils from aromatic plants of Cameroon: their antibacterial activity and ability to permeabilize the cytoplasmic membrane of Listeria innocua examined by flow cytometry","volume":"39","author":"Nguefack","year":"2004","journal-title":"Lett Appl Microbiol"},{"issue":"7\u20138","key":"10.1016\/j.thromres.2005.12.011_bib10","doi-asserted-by":"crossref","first-page":"745","DOI":"10.1016\/j.fitote.2004.08.005","article-title":"Insecticidal activity of certain medicinal plants","volume":"75","author":"Pavela","year":"2004","journal-title":"Fitoterapia"},{"issue":"2","key":"10.1016\/j.thromres.2005.12.011_bib11","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1002\/food.200390021","article-title":"Antifungal activity of peppermint and sweet basil essential oils and their major aroma constituents on some plant pathogenic fungi from the vapor phase","volume":"47","author":"Edris","year":"2003","journal-title":"Nahrung"},{"issue":"11","key":"10.1016\/j.thromres.2005.12.011_bib12","doi-asserted-by":"crossref","first-page":"3197","DOI":"10.1021\/jf021038t","article-title":"Antimicrobial properties of basil and its possible application in food packaging","volume":"51","author":"Suppakul","year":"2003","journal-title":"J Agric Food Chem"},{"issue":"1","key":"10.1016\/j.thromres.2005.12.011_bib13","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/S0167-7012(03)00012-5","article-title":"Comparative studies on the activity of basil\u2014an essential oil from Ocimum basilicum L.\u2014against multidrug resistant clinical isolates of the genera Staphylococcus, Enterococcus and Pseudomonas by using different test methods","volume":"54","author":"Opalchenova","year":"2003","journal-title":"J Microbiol Methods"},{"issue":"3","key":"10.1016\/j.thromres.2005.12.011_bib14","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1016\/S0035-9203(02)90084-2","article-title":"Traditional use of mosquito-repellent plants in western Kenya and their evaluation in semi-field experimental huts against Anopheles gambiae: ethnobotanical studies and application by thermal expulsion and direct burning","volume":"96","author":"Seyoum","year":"2002","journal-title":"Trans R Soc Trop Med Hyg"},{"key":"10.1016\/j.thromres.2005.12.011_bib15","unstructured":"Geeta, Vasudevan DM, Kedlaya R, Deepa S, Ballal M. Activity of Ocimum sanctum (the traditional Indian medicinal plant) against the enteric pathogens. Indian J Med Sci 2001;55(8):434-8, 472."},{"issue":"6","key":"10.1016\/j.thromres.2005.12.011_bib16","doi-asserted-by":"crossref","first-page":"669","DOI":"10.1016\/S0367-326X(01)00270-2","article-title":"Anthelmintic activity of essential oil of Ocimum sanctum and eugenol","volume":"72","author":"Asha","year":"2001","journal-title":"Fitoterapia"},{"issue":"1\u20132","key":"10.1016\/j.thromres.2005.12.011_bib17","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1016\/S0378-5173(01)00764-5","article-title":"The formulation of an effective topical antibacterial product containing Ocimum gratissimum leaf essential oil","volume":"224","author":"Orafidiya","year":"2001","journal-title":"Int J Pharm"},{"issue":"1","key":"10.1016\/j.thromres.2005.12.011_bib18","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1023\/A:1012220908636","article-title":"Cardioprotective potential of Ocimum sanctum in isoproterenol induced myocardial infarction in rats","volume":"225","author":"Sharma","year":"2001","journal-title":"Mol Cell Biochem"},{"issue":"2\u20133","key":"10.1016\/j.thromres.2005.12.011_bib19","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1078\/0944-7113-00289","article-title":"Chemomodulatory efficacy of basil leaf (Ocimum basilicum) on drug metabolizing and antioxidant enzymes, and on carcinogen-induced skin and forestomach papillomagenesis","volume":"11","author":"Dasgupta","year":"2004","journal-title":"Phytomedicine"},{"issue":"3","key":"10.1016\/j.thromres.2005.12.011_bib20","first-page":"262","article-title":"Modulation of glutathione and antioxidant enzymes by Ocimum sanctum and its role in protection against radiation injury","volume":"37","author":"Devi","year":"1999","journal-title":"Indian J Exp Biol"},{"issue":"4","key":"10.1016\/j.thromres.2005.12.011_bib21","first-page":"380","article-title":"Evaluation of antiinflammatory activity of fatty acids of Ocimum sanctum fixed oil","volume":"35","author":"Singh","year":"1997","journal-title":"Indian J Exp Biol"},{"issue":"9","key":"10.1016\/j.thromres.2005.12.011_bib22","doi-asserted-by":"crossref","first-page":"3696","DOI":"10.1021\/jf0480804","article-title":"Effect of chitosan on the biological properties of sweet basil (Ocimum basilicum L.)","volume":"53","author":"Kim","year":"2005","journal-title":"J Agric Food Chem"},{"issue":"3","key":"10.1016\/j.thromres.2005.12.011_bib23","first-page":"185","article-title":"Radioprotective, anticarcinogenic and antioxidant properties of the Indian holy basil, Ocimum sanctum (Tulasi)","volume":"39","author":"Uma Devi","year":"2001","journal-title":"Indian J Exp Biol"},{"issue":"1","key":"10.1016\/j.thromres.2005.12.011_bib24","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1016\/S0944-7113(00)80015-X","article-title":"Antioxidant and cyclooxygenase inhibitory phenolic compounds from Ocimum sanctum Linn","volume":"7","author":"Kelm","year":"2000","journal-title":"Phytomedicine"},{"issue":"3","key":"10.1016\/j.thromres.2005.12.011_bib25","first-page":"248","article-title":"Mechanism of action of antiinflammatory effect of fixed oil of Ocimum basilicum Linn","volume":"37","author":"Singh","year":"1999","journal-title":"Indian J Exp Biol"},{"issue":"10","key":"10.1016\/j.thromres.2005.12.011_bib26","first-page":"1028","article-title":"Comparative evaluation of antiinflammatory potential of fixed oil of different species of Ocimum and its possible mechanism of action","volume":"36","author":"Singh","year":"1998","journal-title":"Indian J Exp Biol"},{"issue":"3","key":"10.1016\/j.thromres.2005.12.011_bib27","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1016\/j.thromres.2003.09.016","article-title":"Effect of age of Armagnac extract and duration of treatment on antithrombotic effects in a rat thrombosis model","volume":"111","author":"Umar","year":"2003","journal-title":"Thromb Res"},{"issue":"5","key":"10.1016\/j.thromres.2005.12.011_bib28","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1111\/j.1472-8206.2004.00285.x","article-title":"Interactions between aspirin and COX-2 inhibitors or NSAIDs in a rat thrombosis model","volume":"18","author":"Umar","year":"2004","journal-title":"Fundam Clin Pharmacol"},{"issue":"2\u20133","key":"10.1016\/j.thromres.2005.12.011_bib29","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1016\/S0049-3848(03)00343-8","article-title":"Effects of armagnac extracts on human platelet function in vitro and on rat arteriovenous shunt thrombosis in vivo","volume":"110","author":"Umar","year":"2003","journal-title":"Thromb Res"},{"issue":"4","key":"10.1016\/j.thromres.2005.12.011_bib30","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1055\/s-0038-1653449","article-title":"In vitro effect of ethanol on ADP and collagen-induced platelet aggregation","volume":"46","author":"Bengmark","year":"1981","journal-title":"Thromb Haemost"},{"issue":"1","key":"10.1016\/j.thromres.2005.12.011_bib31","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1097\/00002826-199901000-00003","article-title":"A novel free radical scavenger, nicaraven, inhibits human platelet aggregation in vitro","volume":"22","author":"Komiya","year":"1999","journal-title":"Clin Neuropharmacol"},{"issue":"3","key":"10.1016\/j.thromres.2005.12.011_bib32","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1055\/s-0038-1647500","article-title":"Effects of ethanol on pathways of platelet aggregation in vitro","volume":"59","author":"Rand","year":"1988","journal-title":"Thromb Haemost"},{"issue":"4","key":"10.1016\/j.thromres.2005.12.011_bib33","first-page":"334","article-title":"Effect of quercetin on platelet aggregation induced by oxyradicals","volume":"17","author":"Xie","year":"1996","journal-title":"Zhongguo Yao Li Xue Bao"},{"issue":"4","key":"10.1016\/j.thromres.2005.12.011_bib34","doi-asserted-by":"crossref","first-page":"1112","DOI":"10.1097\/00006534-199704000-00030","article-title":"Effect of low dose aspirin on thrombus formation at arterial and venous microanastomoses and on the tissue microcirculation","volume":"99","author":"Peter","year":"1997","journal-title":"Plast Reconstr Surg"},{"issue":"1","key":"10.1016\/j.thromres.2005.12.011_bib35","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1111\/j.1476-5381.1982.tb09265.x","article-title":"Fibrin, red cell and platelet interactions in an experimental model of thrombosis","volume":"77","author":"Smith","year":"1982","journal-title":"Br J Pharmacol"},{"issue":"3","key":"10.1016\/j.thromres.2005.12.011_bib36","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1055\/s-0038-1648133","article-title":"The characterisation of thrombus development in an improved model of arterio\u2013venous shunt thrombosis in the rat and the effects of recombinant desulphatohirudin (CGP 39393), heparin, and iloprost","volume":"65","author":"Peters","year":"1991","journal-title":"Thromb Haemost"},{"issue":"1","key":"10.1016\/j.thromres.2005.12.011_bib37","doi-asserted-by":"crossref","first-page":"295","DOI":"10.2307\/2530666","article-title":"Testing the statistical certainty of a response to increasing doses of a drug","volume":"41","author":"Tukey","year":"1985","journal-title":"Biometrics"},{"issue":"6\u20137","key":"10.1016\/j.thromres.2005.12.011_bib38","doi-asserted-by":"crossref","first-page":"474","DOI":"10.1078\/094471103322331412","article-title":"Antiatherogenic effect of Caps HT2, a herbal Ayurvedic medicine formulation","volume":"10","author":"Mary","year":"2003","journal-title":"Phytomedicine"},{"issue":"2\u20133","key":"10.1016\/j.thromres.2005.12.011_bib39","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1016\/S0378-8741(01)00336-1","article-title":"Effect of Ocimum sanctum fixed oil on blood pressure, blood clotting time and pentobarbitone-induced sleeping time","volume":"78","author":"Singh","year":"2001","journal-title":"J Ethnopharmacol"},{"issue":"1\u20132","key":"10.1016\/j.thromres.2005.12.011_bib40","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1016\/0378-8741(89)90088-3","article-title":"Evaluation of the gastric antiulcerogenic effects of Solanum nigrum, Brassica oleracea and Ocimum basilicum in rats","volume":"27","author":"Akhtar","year":"1989","journal-title":"J Ethnopharmacol"},{"issue":"8","key":"10.1016\/j.thromres.2005.12.011_bib41","doi-asserted-by":"crossref","first-page":"829","DOI":"10.1248\/bpb.21.829","article-title":"Anti-HIV-1 activity of herbs in Labiatae","volume":"21","author":"Yamasaki","year":"1998","journal-title":"Biol Pharm Bull"},{"issue":"4","key":"10.1016\/j.thromres.2005.12.011_bib42","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1111\/j.1472-8206.2005.00342.x","article-title":"Cytotoxicity of abnormal Savda Munziq aqueous extract in human hepatoma (HepG2) cells","volume":"19","author":"Yusup","year":"2005","journal-title":"Fundam Clin Pharmacol"},{"issue":"8","key":"10.1016\/j.thromres.2005.12.011_bib43","first-page":"740","article-title":"Study on the constituents of volatile oil from Ocimum basilicum","volume":"28","author":"Wang","year":"2003","journal-title":"Zhongguo Zhong Yao Za Zhi"}],"container-title":["Thrombosis Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0049384805004925?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0049384805004925?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,4,16]],"date-time":"2019-04-16T19:58:27Z","timestamp":1555444707000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0049384805004925"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,1]]},"references-count":43,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2006,1]]}},"alternative-id":["S0049384805004925"],"URL":"https:\/\/doi.org\/10.1016\/j.thromres.2005.12.011","relation":{},"ISSN":["0049-3848"],"issn-type":[{"value":"0049-3848","type":"print"}],"subject":[],"published":{"date-parts":[[2006,1]]}}}