{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T08:47:59Z","timestamp":1791276479920,"version":"4.1.0"},"reference-count":48,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2008,1,1]],"date-time":"2008-01-01T00:00:00Z","timestamp":1199145600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Thrombosis Research"],"published-print":{"date-parts":[[2008,1]]},"DOI":"10.1016\/j.thromres.2007.11.005","type":"journal-article","created":{"date-parts":[[2008,1,2]],"date-time":"2008-01-02T22:33:16Z","timestamp":1199313196000},"page":"221-228","source":"Crossref","is-referenced-by-count":36,"title":["Regulated complement deposition on the surface of human endothelial cells: Effect of tobacco smoke and shear stress"],"prefix":"10.1016","volume":"122","author":[{"given":"Wei","family":"Yin","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Berhane","family":"Ghebrehiwet","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Babette","family":"Weksler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ellinor I.B.","family":"Peerschke","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"10","key":"10.1016\/j.thromres.2007.11.005_bib1","doi-asserted-by":"crossref","first-page":"1731","DOI":"10.1016\/j.jacc.2003.12.047","article-title":"The pathophysiology of cigarette smoking and cardiovascular disease: an update","volume":"43","author":"Ambrose","year":"2004","journal-title":"J Am Coll Cardiol"},{"issue":"3","key":"10.1016\/j.thromres.2007.11.005_bib2","doi-asserted-by":"crossref","first-page":"314","DOI":"10.1165\/rcmb.2005-0428OC","article-title":"Cigarette smoke-induced Egr-1 upregulates proinflammatory cytokines in pulmonary epithelial cells","volume":"35","author":"Reynolds","year":"2006","journal-title":"Am J Respir Cell Mol Biol"},{"issue":"20","key":"10.1016\/j.thromres.2007.11.005_bib3","doi-asserted-by":"crossref","first-page":"2684","DOI":"10.1161\/CIRCULATIONAHA.104.492215","article-title":"Cardiovascular effects of secondhand smoke: nearly as large as smoking","volume":"111","author":"Barnoya","year":"2005","journal-title":"Circulation"},{"key":"10.1016\/j.thromres.2007.11.005_bib4","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1186\/1465-9921-6-22","article-title":"Acute effects of cigarette smoking on inflammation in healthy intermittent smokers","volume":"6","author":"van d","year":"2005","journal-title":"Respir Res"},{"issue":"2","key":"10.1016\/j.thromres.2007.11.005_bib5","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1001\/jama.279.2.119","article-title":"Cigarette smoking and progression of atherosclerosis: the Atherosclerosis Risk in Communities (ARIC) Study","volume":"279","author":"Howard","year":"1998","journal-title":"JAMA"},{"issue":"8","key":"10.1016\/j.thromres.2007.11.005_bib6","doi-asserted-by":"crossref","first-page":"713","DOI":"10.1136\/thx.2003.012468","article-title":"Acute effects of cigarette smoke on inflammation and oxidative stress: a review","volume":"59","author":"van der Vaart","year":"2004","journal-title":"Thorax"},{"issue":"2","key":"10.1016\/j.thromres.2007.11.005_bib7","first-page":"121","article-title":"Damaging effect of cigarette smoke extract on primary cultured human umbilical vein endothelial cells and its mechanism","volume":"17","author":"Yang","year":"2004","journal-title":"Biomed Environ Sci"},{"issue":"3","key":"10.1016\/j.thromres.2007.11.005_bib8","doi-asserted-by":"crossref","first-page":"H1293","DOI":"10.1152\/ajpheart.2001.280.3.H1293","article-title":"Effects of tobacco smoke and benzo[a]pyrene on human endothelial cell and monocyte stress responses","volume":"280","author":"Vayssier-Taussat","year":"2001","journal-title":"Am J Physiol Heart Circ Physiol"},{"issue":"2-3","key":"10.1016\/j.thromres.2007.11.005_bib9","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/j.tox.2005.04.005","article-title":"Kinetic analysis of cytokine response to cigarette smoke condensate by human endothelial and monocytic cells","volume":"212","author":"Nordskog","year":"2005","journal-title":"Toxicology"},{"issue":"2","key":"10.1016\/j.thromres.2007.11.005_bib10","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1016\/j.cyto.2005.04.007","article-title":"Soluble ICAM-1: a marker of vascular inflammation and lifestyle","volume":"31","author":"Witkowska","year":"2005","journal-title":"Cytokine"},{"issue":"3","key":"10.1016\/j.thromres.2007.11.005_bib11","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1007\/s11883-006-0079-8","article-title":"Vascular shear stress and activation of inflammatory genes","volume":"8","author":"World","year":"2006","journal-title":"Curr Atheroscler Rep"},{"issue":"3","key":"10.1016\/j.thromres.2007.11.005_bib12","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1016\/S0079-6107(02)00052-4","article-title":"Fluid shear stress and the vascular endothelium: for better and for worse","volume":"81","author":"Resnick","year":"2003","journal-title":"Prog Biophys Mol Biol"},{"issue":"5","key":"10.1016\/j.thromres.2007.11.005_bib13","doi-asserted-by":"crossref","first-page":"1525","DOI":"10.1182\/blood.V88.5.1525.1525","article-title":"Platelets and shear stress","volume":"88","author":"Kroll","year":"1996","journal-title":"Blood"},{"issue":"4 Pt 1","key":"10.1016\/j.thromres.2007.11.005_bib14","first-page":"L254","article-title":"Complement activation by cigarette smoke","volume":"260","author":"Robbins","year":"1991","journal-title":"Am J Physiol"},{"issue":"3","key":"10.1016\/j.thromres.2007.11.005_bib15","doi-asserted-by":"crossref","first-page":"1000","DOI":"10.1172\/JCI111760","article-title":"Cigarette smoke can activate the alternative pathway of complement in vitro by modifying the third component of complement","volume":"75","author":"Kew","year":"1985","journal-title":"J Clin Invest"},{"issue":"8","key":"10.1016\/j.thromres.2007.11.005_bib16","doi-asserted-by":"crossref","first-page":"759","DOI":"10.1016\/j.molimm.2004.04.020","article-title":"Expression of gC1q-R\/p33 and its major ligands in human atherosclerotic lesions","volume":"41","author":"Peerschke","year":"2004","journal-title":"Mol Immunol"},{"issue":"2","key":"10.1016\/j.thromres.2007.11.005_bib17","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1056\/NEJM199901143400207","article-title":"Atherosclerosis\u2014an inflammatory disease","volume":"340","author":"Ross","year":"1999","journal-title":"N Engl J Med"},{"issue":"1","key":"10.1016\/j.thromres.2007.11.005_bib18","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/j.ahj.2004.12.019","article-title":"Inflammation and coronary artery disease","volume":"150","author":"Tiong","year":"2005","journal-title":"Am. Heart J"},{"issue":"2-3","key":"10.1016\/j.thromres.2007.11.005_bib19","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1016\/j.molimm.2004.03.014","article-title":"cC1q-R (calreticulin) and gC1q-R\/p33: ubiquitously expressed multi-ligand binding cellular proteins involved in inflammation and infection","volume":"41","author":"Ghebrehiwet","year":"2004","journal-title":"Mol Immunol"},{"key":"10.1016\/j.thromres.2007.11.005_bib20","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1007\/0-387-34134-X_7","article-title":"gC1qR\/p33 serves as a molecular bridge between the complement and contact activation systems and is an important catalyst in inflammation","volume":"586","author":"Ghebrehiwet","year":"2006","journal-title":"Adv Exp Med Biol"},{"issue":"9","key":"10.1016\/j.thromres.2007.11.005_bib21","doi-asserted-by":"crossref","first-page":"2228","DOI":"10.1016\/j.molimm.2006.11.012","article-title":"Classical pathway complement activation on human endothelial cells","volume":"44","author":"Yin","year":"2007","journal-title":"Mol Immunol"},{"issue":"2 Pt 1","key":"10.1016\/j.thromres.2007.11.005_bib22","doi-asserted-by":"crossref","first-page":"C450","DOI":"10.1152\/ajpcell.1999.276.2.C450","article-title":"Hypoxia-induced expression of complement receptor type 1 (CR1, CD35) in human vascular endothelial cells","volume":"276","author":"Collard","year":"1999","journal-title":"Am J Physiol"},{"issue":"2-3","key":"10.1016\/j.thromres.2007.11.005_bib23","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1016\/j.clim.2005.10.014","article-title":"Membrane complement regulatory proteins","volume":"118","author":"Kim","year":"2006","journal-title":"Clin Immunol"},{"issue":"3","key":"10.1016\/j.thromres.2007.11.005_bib24","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1023\/A:1015585530204","article-title":"Human umbilical vein endothelial cells express complement receptor 1 (CD35) and complement receptor 4 (CD11c\/CD18) in vitro","volume":"26","author":"Langeggen","year":"2002","journal-title":"Inflammation"},{"issue":"1","key":"10.1016\/j.thromres.2007.11.005_bib25","first-page":"25","article-title":"Characterization of a newly established human bone marrow endothelial cell line: distinct adhesive properties for hematopoietic progenitors compared with human umbilical vein endothelial cells","volume":"76","author":"Schweitzer","year":"1997","journal-title":"Lab Invest"},{"issue":"9","key":"10.1016\/j.thromres.2007.11.005_bib26","doi-asserted-by":"crossref","first-page":"2035","DOI":"10.1111\/j.1538-7836.2006.02065.x","article-title":"Blood platelets activate the classical pathway of human complement","volume":"4","author":"Peerschke","year":"2006","journal-title":"J Thromb Haemost"},{"issue":"2","key":"10.1016\/j.thromres.2007.11.005_bib27","doi-asserted-by":"crossref","first-page":"664","DOI":"10.1158\/0008-5472.664.65.2","article-title":"Levels of cyclooxygenase-2 are increased in the oral mucosa of smokers: evidence for the role of epidermal growth factor receptor and its ligands","volume":"65","author":"Moraitis","year":"2005","journal-title":"Cancer Res"},{"key":"10.1016\/j.thromres.2007.11.005_bib28","doi-asserted-by":"crossref","first-page":"1831","DOI":"10.1096\/fj.06-7557com","article-title":"Tobacco smoke cooperates with interleukin-1b to alter b-catenin trafficking in vascular endothelium resulting in increased permeability and induction of cyclooxygenase-2 expression in vitro and in vivo","volume":"21","author":"Barbieri","year":"2007","journal-title":"FASEB J"},{"key":"10.1016\/j.thromres.2007.11.005_bib29","doi-asserted-by":"crossref","first-page":"733","DOI":"10.1016\/j.febslet.2004.12.052","article-title":"Endogenous nitric oxide activation protects against cigarette smoking induced apoptosis in endothelial cells","volume":"579","author":"Raveendran","year":"2005","journal-title":"FEBS Lett"},{"key":"10.1016\/j.thromres.2007.11.005_bib30","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1165\/rcmb.2004-0198OC","article-title":"Matrix metalloproteinase\/epidernal growth factor receptor\/mitogen-activated protein kinase signaling regulate fra-1 induction by cigarette smoke in lung epithelial cells","volume":"32","author":"Zhang","year":"2005","journal-title":"Am J Respir Cell Mol Biol"},{"issue":"10","key":"10.1016\/j.thromres.2007.11.005_bib31","first-page":"1018","article-title":"Hemodynamics and atherosclerosis. Insights and perspectives gained from studies of human arteries","volume":"112","author":"Glagov","year":"1988","journal-title":"Arch Pathol Lab Med"},{"issue":"3","key":"10.1016\/j.thromres.2007.11.005_bib32","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1016\/S0162-3109(99)00178-2","article-title":"C3a and C5a enhance granulocyte adhesion to endothelial and epithelial cell monolayers: epithelial and endothelial priming is required for C3a-induced eosinophil adhesion","volume":"46","author":"Jagels","year":"2000","journal-title":"Immunopharmacology"},{"issue":"1\u20133","key":"10.1016\/j.thromres.2007.11.005_bib33","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1385\/IR:36:1:197","article-title":"Complement-mediated activation of the adaptive immune responses: role of C3d in linking the innate and adaptive immunity","volume":"36","author":"Toapanta","year":"2006","journal-title":"Immunol Res"},{"issue":"1","key":"10.1016\/j.thromres.2007.11.005_bib34","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1513\/pats.200407-038MS","article-title":"The role of smoking in coagulation and thromboembolism in chronic obstructive pulmonary disease","volume":"2","author":"Tapson","year":"2005","journal-title":"Proc Am Thorac Soc"},{"issue":"5","key":"10.1016\/j.thromres.2007.11.005_bib35","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1080\/01902140600817457","article-title":"Lung inflammation in rats following subchronic exposure to cigarette mainstream smoke","volume":"32","author":"Friedrichs","year":"2006","journal-title":"Exp Lung Res"},{"issue":"2","key":"10.1016\/j.thromres.2007.11.005_bib36","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1385\/IR:34:2:157","article-title":"The role of complement in danger sensing and transmission","volume":"34","author":"Kohl","year":"2006","journal-title":"Immunol Res"},{"issue":"11","key":"10.1016\/j.thromres.2007.11.005_bib37","doi-asserted-by":"crossref","first-page":"1089","DOI":"10.1016\/j.molimm.2004.06.011","article-title":"Complement: a unique innate immune sensor for danger signals","volume":"41","author":"Gasque","year":"2004","journal-title":"Mol Immunol"},{"key":"10.1016\/j.thromres.2007.11.005_bib38","doi-asserted-by":"crossref","first-page":"1703","DOI":"10.2174\/092986707781058959","article-title":"Smoking, oxidant stress and cardiovascular disease","volume":"14","author":"Bernhard","year":"2007","journal-title":"Curr Med Chem"},{"key":"10.1016\/j.thromres.2007.11.005_bib39","doi-asserted-by":"crossref","first-page":"767","DOI":"10.1080\/08958370701401418","article-title":"Oxidant stress in smokers and non smokers","volume":"19","author":"Isik","year":"2007","journal-title":"Inhal Toxicol"},{"key":"10.1016\/j.thromres.2007.11.005_bib40","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1097\/01.psp.0000249918.19016.f6","article-title":"Effect of cigarette smoking on the oxidant\/antioxidant balance in healthy subjects","volume":"14","author":"Chavez","year":"2007","journal-title":"Am J Ther"},{"key":"10.1016\/j.thromres.2007.11.005_bib41","series-title":"The immune system in health and disease","article-title":"Immunobiology","author":"Janeway","year":"1997"},{"issue":"6","key":"10.1016\/j.thromres.2007.11.005_bib42","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1016\/S0022-2143(99)90183-X","article-title":"Up-regulation of endothelial cell binding proteins\/receptors for complement component C1q by inflammatory cytokines","volume":"133","author":"Guo","year":"1999","journal-title":"J Lab Clin Med"},{"issue":"2-3","key":"10.1016\/j.thromres.2007.11.005_bib43","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1016\/S0162-3109(99)00136-8","article-title":"Interaction of factor XII and high molecular weight kininogen with cytokeratin 1 and gC1qR of vascular endothelial cells and with aggregated Abeta protein of Alzheimer's disease","volume":"43","author":"Joseph","year":"1999","journal-title":"Immunopharmacology"},{"issue":"1","key":"10.1016\/j.thromres.2007.11.005_bib44","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1160\/TH03-07-0471","article-title":"Interaction of high molecular weight kininogen binding proteins on endothelial cells","volume":"91","author":"Joseph","year":"2004","journal-title":"Thromb Haemost"},{"issue":"6","key":"10.1016\/j.thromres.2007.11.005_bib45","doi-asserted-by":"crossref","first-page":"1148","DOI":"10.1016\/j.jaci.2005.01.068","article-title":"Expression of the anaphylatoxin receptors C3aR and C5aR is increased in fatal asthma","volume":"115","author":"Fregonese","year":"2005","journal-title":"J Allergy Clin Immunol"},{"issue":"10","key":"10.1016\/j.thromres.2007.11.005_bib46","doi-asserted-by":"crossref","first-page":"5299","DOI":"10.1073\/pnas.76.10.5299","article-title":"C4a: the third anaphylatoxin of the human complement system","volume":"76","author":"Gorski","year":"1979","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"11","key":"10.1016\/j.thromres.2007.11.005_bib47","doi-asserted-by":"crossref","first-page":"1626","DOI":"10.1016\/j.amjcard.2005.12.056","article-title":"Dynamic expression of the membrane attack complex (MAC) of the complement system in failing human myocardium","volume":"97","author":"Oliveira","year":"2006","journal-title":"Am J Cardiol"},{"issue":"2","key":"10.1016\/j.thromres.2007.11.005_bib48","doi-asserted-by":"crossref","first-page":"1107","DOI":"10.1074\/jbc.M109322200","article-title":"Decay-accelerating factor (DAF), complement receptor 1 (CR1), and factor H dissociate the complement AP C3 convertase (C3bBb) via sites on the type A domain of Bb","volume":"277","author":"Hourcade","year":"2002","journal-title":"J Biol Chem"}],"container-title":["Thrombosis Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0049384807004501?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0049384807004501?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2023,5,15]],"date-time":"2023-05-15T16:37:48Z","timestamp":1684168668000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0049384807004501"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,1]]},"references-count":48,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2008,1]]}},"alternative-id":["S0049384807004501"],"URL":"https:\/\/doi.org\/10.1016\/j.thromres.2007.11.005","relation":{},"ISSN":["0049-3848"],"issn-type":[{"value":"0049-3848","type":"print"}],"subject":[],"published":{"date-parts":[[2008,1]]}}}