{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,9,5]],"date-time":"2024-09-05T07:12:07Z","timestamp":1725520327271},"reference-count":30,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2010,2,1]],"date-time":"2010-02-01T00:00:00Z","timestamp":1264982400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Thrombosis Research"],"published-print":{"date-parts":[[2010,2]]},"DOI":"10.1016\/j.thromres.2009.07.018","type":"journal-article","created":{"date-parts":[[2009,10,2]],"date-time":"2009-10-02T08:46:46Z","timestamp":1254473206000},"page":"171-177","source":"Crossref","is-referenced-by-count":5,"title":["Coagulation activation and ultrasound characteristics in patients with carotid artery disease"],"prefix":"10.1016","volume":"125","author":[{"given":"Tilo","family":"K\u00f6lbel","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Isabel","family":"Goncalves","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nuno","family":"Dias","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karin","family":"Strandberg","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stefan","family":"Acosta","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anders","family":"Gotts\u00e4ter","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"5","key":"10.1016\/j.thromres.2009.07.018_bib1","doi-asserted-by":"crossref","first-page":"755","DOI":"10.1016\/S0741-5214(96)70237-9","article-title":"Atherosclerotic plaque rupture in symptomatic carotid artery stenosis","volume":"23","author":"Carr","year":"1996","journal-title":"J Vasc Surg"},{"issue":"1","key":"10.1016\/j.thromres.2009.07.018_bib2","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1161\/hc2601.091704","article-title":"Ultrasonic echolucent carotid plaques predict future strokes","volume":"104","author":"Gronholdt","year":"2001","journal-title":"Circulation"},{"issue":"17","key":"10.1016\/j.thromres.2009.07.018_bib3","doi-asserted-by":"crossref","first-page":"2171","DOI":"10.1161\/01.CIR.103.17.2171","article-title":"Echolucent plaques are associated with high risk of ischemic cerebrovascular events in carotid stenosis: the tromso study","volume":"103","author":"Mathiesen","year":"2001","journal-title":"Circulation"},{"issue":"5","key":"10.1016\/j.thromres.2009.07.018_bib4","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1097\/00041433-200310000-00012","article-title":"Echolucent rupture-prone plaques","volume":"14","author":"Nordestgaard","year":"2003","journal-title":"Curr Opin Lipidol"},{"issue":"3","key":"10.1016\/j.thromres.2009.07.018_bib5","doi-asserted-by":"crossref","first-page":"616","DOI":"10.1161\/01.STR.0000058157.69113.F6","article-title":"Changes related to age and cerebrovascular symptoms in the extracellular matrix of human carotid plaques","volume":"34","author":"Goncalves","year":"2003","journal-title":"Stroke"},{"issue":"3","key":"10.1016\/j.thromres.2009.07.018_bib6","doi-asserted-by":"crossref","first-page":"594","DOI":"10.1161\/01.CIR.95.3.594","article-title":"Tissue factor modulates the thrombogenicity of human atherosclerotic plaques","volume":"95","author":"Toschi","year":"1997","journal-title":"Circulation"},{"issue":"4","key":"10.1016\/j.thromres.2009.07.018_bib7","first-page":"405","article-title":"Increased tissue factor, MMP-8, and D-dimer expression in diabetic patients with unstable advanced carotid atherosclerosis","volume":"3","author":"Krupinski","year":"2007","journal-title":"Vasc Health Risk Manage"},{"issue":"2","key":"10.1016\/j.thromres.2009.07.018_bib8","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1016\/S0049-3848(98)00165-0","article-title":"Paramo JA. Measurement of prethrombotic markers in the assessment of acquired hypercoagulable states","volume":"93","author":"Lopez","year":"1999","journal-title":"Thromb Res"},{"issue":"3","key":"10.1016\/j.thromres.2009.07.018_bib9","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1159\/000087201","article-title":"Association of the fibrinolytic system and hemorheology with symptoms in patients with carotid occlusive disease","volume":"20","author":"Soinne","year":"2005","journal-title":"Cerebrovasc Dis (Basel, Switzerland)"},{"issue":"3","key":"10.1016\/j.thromres.2009.07.018_bib10","doi-asserted-by":"crossref","first-page":"602","DOI":"10.1160\/TH07-08-0493","article-title":"Increased thrombin generation in persons with echogenic carotid plaques","volume":"99","author":"With Noto","year":"2008","journal-title":"Thromb Haemost"},{"issue":"3","key":"10.1016\/j.thromres.2009.07.018_bib11","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1111\/j.1365-2796.2004.01444.x","article-title":"Blood coagulation and its regulation by anticoagulant pathways: genetic pathogenesis of bleeding and thrombotic diseases","volume":"257","author":"Dahlback","year":"2005","journal-title":"J Intern Med."},{"issue":"9215","key":"10.1016\/j.thromres.2009.07.018_bib12","doi-asserted-by":"crossref","first-page":"1627","DOI":"10.1016\/S0140-6736(00)02225-X","article-title":"Blood coagulation","volume":"355","author":"Dahlback","year":"2000","journal-title":"Lancet"},{"issue":"42","key":"10.1016\/j.thromres.2009.07.018_bib13","doi-asserted-by":"crossref","first-page":"26486","DOI":"10.1016\/S0021-9258(18)47220-1","article-title":"Identification, cloning, and regulation of a novel endothelial cell protein C\/activated protein C receptor","volume":"269","author":"Fukudome","year":"1994","journal-title":"J Biol Chem"},{"issue":"2","key":"10.1016\/j.thromres.2009.07.018_bib14","first-page":"604","article-title":"A sensitive immunochemical assay for measuring the concentration of the activated protein C-protein C inhibitor complex in plasma: use of a catcher antibody specific for the complexed\/cleaved form of the inhibitor","volume":"86","author":"Strandberg","year":"2001","journal-title":"Thromb Haemost."},{"issue":"2","key":"10.1016\/j.thromres.2009.07.018_bib15","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1177\/1538574407311108","article-title":"Activated protein C-protein C inhibitor complex in patients with abdominal aortic aneurysms: is it associated with diameter and growth rate?","volume":"42","author":"K\u00f6lbel","year":"2008","journal-title":"Vasc Endovascular Surg"},{"issue":"5","key":"10.1016\/j.thromres.2009.07.018_bib16","doi-asserted-by":"crossref","first-page":"947","DOI":"10.1055\/s-0037-1613485","article-title":"Stabilyte tubes that contain strongly acidic citrate prevent in vitro complex formation between activated protein C and protein C inhibitor","volume":"89","author":"Strandberg","year":"2003","journal-title":"Thromb Haemost."},{"issue":"1","key":"10.1016\/j.thromres.2009.07.018_bib17","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1046\/j.1365-2796.2000.00568.x","article-title":"Long-term outcome of the Malmo preventive project: mortality and cardiovascular morbidity","volume":"247","author":"Berglund","year":"2000","journal-title":"J Intern Med."},{"issue":"3","key":"10.1016\/j.thromres.2009.07.018_bib18","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1016\/S1078-5884(96)80252-8","article-title":"Accuracy of duplex sonography before carotid endarterectomy\u2013a comparison with angiography","volume":"12","author":"Hansen","year":"1996","journal-title":"Eur J Vasc Endovasc Surg."},{"issue":"9113","key":"10.1016\/j.thromres.2009.07.018_bib19","doi-asserted-by":"crossref","first-page":"1379","DOI":"10.1016\/S0140-6736(97)09292-1","article-title":"Randomised trial of endarterectomy for recently symptomatic carotid stenosis: final results of the MRC European Carotid Surgery Trial (ECST)","volume":"351","year":"1998","journal-title":"Lancet"},{"issue":"6","key":"10.1016\/j.thromres.2009.07.018_bib20","first-page":"676","article-title":"Carotid artery atheroma: comparison of preoperative B-mode ultrasound appearance with carotid endarterectomy specimen pathology","volume":"29","author":"Gray-Weale","year":"1988","journal-title":"J Cardiovasc Surg"},{"issue":"9420","key":"10.1016\/j.thromres.2009.07.018_bib21","doi-asserted-by":"crossref","first-page":"1491","DOI":"10.1016\/S0140-6736(04)16146-1","article-title":"Prevention of disabling and fatal strokes by successful carotid endarterectomy in patients without recent neurological symptoms: randomised controlled trial","volume":"363","author":"Halliday","year":"2004","journal-title":"Lancet"},{"issue":"5","key":"10.1016\/j.thromres.2009.07.018_bib22","doi-asserted-by":"crossref","first-page":"935","DOI":"10.1016\/j.jvs.2006.01.019","article-title":"Activated protein C-protein C inhibitor complex: a new biological marker for aortic aneurysms","volume":"43","author":"K\u00f6lbel","year":"2006","journal-title":"J Vasc Surg"},{"issue":"8","key":"10.1016\/j.thromres.2009.07.018_bib23","doi-asserted-by":"crossref","first-page":"1856","DOI":"10.1161\/01.STR.31.8.1856","article-title":"Hemostatic markers in patients at risk of cerebral ischemia","volume":"31","author":"Cote","year":"2000","journal-title":"Stroke"},{"issue":"8752","key":"10.1016\/j.thromres.2009.07.018_bib24","doi-asserted-by":"crossref","first-page":"1235","DOI":"10.1016\/0140-6736(91)92916-P","article-title":"MRC European Carotid Surgery Trial: interim results for symptomatic patients with severe (70-99%) or with mild (0-29%) carotid stenosis. European Carotid Surgery Trialists' Collaborative Group","volume":"337","year":"1991","journal-title":"Lancet"},{"issue":"7435","key":"10.1016\/j.thromres.2009.07.018_bib25","doi-asserted-by":"crossref","first-page":"326","DOI":"10.1136\/bmj.37991.635266.44","article-title":"Population based study of early risk of stroke after transient ischaemic attack or minor stroke: implications for public education and organisation of services","volume":"328","author":"Coull","year":"2004","journal-title":"Bmj"},{"issue":"9455","key":"10.1016\/j.thromres.2009.07.018_bib26","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1016\/S0140-6736(05)70156-2","article-title":"Treating individuals 3: from subgroups to individuals: general principles and the example of carotid endarterectomy","volume":"365","author":"Rothwell","year":"2005","journal-title":"Lancet"},{"issue":"4","key":"10.1016\/j.thromres.2009.07.018_bib27","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1111\/j.1600-0404.2004.00304.x","article-title":"Serial changes in fibrinolysis and coagulation activation markers in acute and convalescent phase of ischemic stroke","volume":"110","author":"Haapaniemi","year":"2004","journal-title":"Acta neurol Scand"},{"issue":"6","key":"10.1016\/j.thromres.2009.07.018_bib28","doi-asserted-by":"crossref","first-page":"1400","DOI":"10.1055\/s-0037-1616742","article-title":"Complexes between activated protein C and protein C inhibitor measured with a new method: comparison of performance with other markers of hypercoagulability in the diagnosis of deep vein thrombosis","volume":"86","author":"Strandberg","year":"2001","journal-title":"Thromb Haemost."},{"issue":"7","key":"10.1016\/j.thromres.2009.07.018_bib29","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1097\/00001721-200110000-00001","article-title":"A new method to measure plasma levels of activated protein C in complex with protein C inhibitor in patients with acute coronary syndromes","volume":"12","author":"Strandberg","year":"2001","journal-title":"Blood Coagul Fibrinolysis."},{"issue":"3","key":"10.1016\/j.thromres.2009.07.018_bib30","doi-asserted-by":"crossref","first-page":"567","DOI":"10.1160\/TH05-01-0042","article-title":"A model for the harmonisation of test results of different quantitative D-dimer methods","volume":"95","author":"Meijer","year":"2006","journal-title":"Thromb Haemost."}],"container-title":["Thrombosis Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0049384809003879?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0049384809003879?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2021,10,11]],"date-time":"2021-10-11T18:46:02Z","timestamp":1633977962000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0049384809003879"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,2]]},"references-count":30,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2010,2]]}},"alternative-id":["S0049384809003879"],"URL":"https:\/\/doi.org\/10.1016\/j.thromres.2009.07.018","relation":{},"ISSN":["0049-3848"],"issn-type":[{"value":"0049-3848","type":"print"}],"subject":[],"published":{"date-parts":[[2010,2]]}}}