{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T18:44:26Z","timestamp":1790361866574,"version":"4.1.0"},"reference-count":47,"publisher":"Elsevier BV","issue":"3","content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Thrombosis Research"],"published-print":{"date-parts":[[2013,9]]},"DOI":"10.1016\/j.thromres.2013.07.022","type":"journal-article","created":{"date-parts":[[2013,8,2]],"date-time":"2013-08-02T02:21:33Z","timestamp":1375410093000},"page":"386-391","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":41,"title":["Comparison of markers of coagulation activation and thrombin generation test in uncomplicated pregnancies"],"prefix":"10.1016","volume":"132","author":[{"given":"Berangere","family":"Joly","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Virginie","family":"Barbay","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeanne-Yvonne","family":"Borg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Veronique","family":"Le Cam-Duchez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"4","key":"10.1016\/j.thromres.2013.07.022_bb0005","doi-asserted-by":"crossref","first-page":"718","DOI":"10.1160\/TH09-10-0704","article-title":"Haemostatic reference intervals in pregnancy","volume":"103","author":"Szecsi","year":"2010","journal-title":"Thromb Haemost"},{"issue":"5\u20136","key":"10.1016\/j.thromres.2013.07.022_bb0010","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1016\/j.thromres.2004.08.004","article-title":"Haemostatic changes in pregnancy","volume":"114","author":"Brenner","year":"2004","journal-title":"Thromb Res"},{"issue":"3","key":"10.1016\/j.thromres.2013.07.022_bb0015","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1160\/TH05-11-0753","article-title":"Haemostasis and pregnancy","volume":"95","author":"Franchini","year":"2006","journal-title":"Thromb Haemost"},{"issue":"2","key":"10.1016\/j.thromres.2013.07.022_bb0020","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1160\/TH07-05-0359","article-title":"Calibrated automated thrombin generation in normal uncomplicated pregnancy","volume":"99","author":"Rosenkranz","year":"2008","journal-title":"Thromb Haemost"},{"issue":"4","key":"10.1016\/j.thromres.2013.07.022_bb0025","first-page":"1232","article-title":"Prospective evaluation of hemostatic system activation and thrombin potential in healthy pregnant women with and without factor V Leiden","volume":"82","author":"Eichinger","year":"1999","journal-title":"Thromb Haemost"},{"issue":"1","key":"10.1016\/j.thromres.2013.07.022_bb0030","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/j.thromres.2004.04.008","article-title":"Fibrinogen and high molecular weight fibrinogen during and after normal pregnancy","volume":"114","author":"Manten","year":"2004","journal-title":"Thromb Res"},{"issue":"1","key":"10.1016\/j.thromres.2013.07.022_bb0035","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1046\/j.1365-2141.1995.00271.x","article-title":"Activated protein C sensitivity ratio in pregnant women at delivery","volume":"92","author":"Mathonnet","year":"1996","journal-title":"Br J Haematol"},{"issue":"4","key":"10.1016\/j.thromres.2013.07.022_bb0040","doi-asserted-by":"crossref","first-page":"1030","DOI":"10.1055\/s-0038-1646049","article-title":"Fibrinolytic response to venous occlusion and fibrin fragment D-dimer levels in normal and complicated pregnancy","volume":"58","author":"Ballegeer","year":"1987","journal-title":"Thromb Haemost"},{"issue":"5","key":"10.1016\/j.thromres.2013.07.022_bb0045","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1016\/0049-3848(95)00073-Z","article-title":"D-dimer concentrations during normal pregnancy, as measured by ELISA","volume":"78","author":"Francalanci","year":"1995","journal-title":"Thromb Res"},{"issue":"5","key":"10.1016\/j.thromres.2013.07.022_bb0050","doi-asserted-by":"crossref","first-page":"825","DOI":"10.1373\/clinchem.2004.044883","article-title":"D-dimer concentrations in normal pregnancy: new diagnostic thresholds are needed","volume":"51","author":"Kline","year":"2005","journal-title":"Clin Chem"},{"issue":"2","key":"10.1016\/j.thromres.2013.07.022_bb0055","first-page":"235","article-title":"Maternal plasma D-dimer levels in normal and complicated pregnancies","volume":"81","author":"Nolan","year":"1993","journal-title":"Obstet Gynecol"},{"issue":"1","key":"10.1016\/j.thromres.2013.07.022_bb0060","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1007\/BF02827245","article-title":"D-dimer plasma levels during normal pregnancy measured by specific ELISA","volume":"27","author":"Francalanci","year":"1997","journal-title":"Int J Clin Lab Res"},{"issue":"4","key":"10.1016\/j.thromres.2013.07.022_bb0065","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1055\/s-2005-922483","article-title":"D-dimer testing in pregnancy","volume":"5","author":"Eichinger","year":"2005","journal-title":"Semin Vasc Med"},{"issue":"2","key":"10.1016\/j.thromres.2013.07.022_bb0070","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1080\/01443610802649045","article-title":"D-dimers as a screening test for venous thromboembolism in pregnancy: is it of any use?","volume":"29","author":"Damodaram","year":"2009","journal-title":"J Obstet Gynaecol"},{"issue":"2","key":"10.1016\/j.thromres.2013.07.022_bb0075","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1160\/TH09-10-0679","article-title":"Endogenous thrombin potential, prothrombin fragment 1+2 and D-dimers during pregnancy","volume":"103","author":"Dargaud","year":"2010","journal-title":"Thromb Haemost"},{"issue":"5","key":"10.1016\/j.thromres.2013.07.022_bb0080","doi-asserted-by":"crossref","first-page":"1231","DOI":"10.1007\/s00404-011-2137-x","article-title":"Changes in coagulation and hemodynamics during pregnancy: a prospective longitudinal study of 58 cases","volume":"285","author":"Hui","year":"2012","journal-title":"Arch Gynecol Obstet"},{"issue":"1","key":"10.1016\/j.thromres.2013.07.022_bb0085","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1160\/TH06-10-0574","article-title":"The effect of dalteparin on coagulation activation during pregnancy in women with thrombophilia. A randomized trial","volume":"98","author":"Abou-Nassar","year":"2007","journal-title":"Thromb Haemost"},{"issue":"2","key":"10.1016\/j.thromres.2013.07.022_bb0090","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1055\/s-2003-38897","article-title":"Hemostasis during normal pregnancy and puerperium","volume":"29","author":"Hellgren","year":"2003","journal-title":"Semin Thromb Hemost"},{"issue":"3","key":"10.1016\/j.thromres.2013.07.022_bb0095","doi-asserted-by":"crossref","first-page":"382","DOI":"10.1067\/mob.2001.109397","article-title":"Coagulation activation markers do not correlate with the clinical risk of thrombosis in pregnant women","volume":"184","author":"Bombeli","year":"2001","journal-title":"Am J Obstet Gynecol"},{"issue":"1","key":"10.1016\/j.thromres.2013.07.022_bb0100","first-page":"45","article-title":"Blood coagulation and fibrinolysis during normal pregnancy","volume":"29","author":"Van Wersch","year":"1991","journal-title":"Eur J Clin Chem Clin Biochem"},{"issue":"4","key":"10.1016\/j.thromres.2013.07.022_bb0105","doi-asserted-by":"crossref","first-page":"775","DOI":"10.1046\/j.1365-2141.1997.1222936.x","article-title":"Epidemiology of coagulation factors, inhibitors and activation markers: the Third Glasgow MONICA Survey. I. Illustrative reference ranges by age, sex and hormone use","volume":"97","author":"Lowe","year":"1997","journal-title":"Br J Haematol"},{"issue":"5","key":"10.1016\/j.thromres.2013.07.022_bb0110","doi-asserted-by":"crossref","first-page":"807","DOI":"10.1160\/TH06-04-0222","article-title":"The role of fibrin monomers in optimizing the diagnostic work-up of deep vein thrombosis","volume":"97","author":"Schutgens","year":"2007","journal-title":"Thromb Haemost"},{"issue":"6","key":"10.1016\/j.thromres.2013.07.022_bb0115","doi-asserted-by":"crossref","first-page":"1228","DOI":"10.1160\/TH11-07-0489","article-title":"Fibrin-related markers in patients with septic shock: individual comparison of D-dimers and fibrin monomers impacts on prognosis","volume":"106","author":"Gris","year":"2011","journal-title":"Thromb Haemost"},{"issue":"4","key":"10.1016\/j.thromres.2013.07.022_bb0120","doi-asserted-by":"crossref","first-page":"890","DOI":"10.1213\/ANE.0b013e3182652a33","article-title":"Prospective longitudinal study of thromboelastography and standard hemostatic laboratory tests in healthy women during normal pregnancy","volume":"115","author":"Karlsson","year":"2012","journal-title":"Anesth Analg"},{"issue":"Pt 5","key":"10.1016\/j.thromres.2013.07.022_bb0125","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1258\/000456307781646076","article-title":"Fibrin monomer complex in normal pregnant women: a potential thrombotic marker in pregnancy","volume":"44","author":"Onishi","year":"2007","journal-title":"Ann Clin Biochem"},{"issue":"5","key":"10.1016\/j.thromres.2013.07.022_bb0130","first-page":"553","article-title":"Thrombin generation, a function test of the haemostatic-thrombotic system","volume":"96","author":"Hemker","year":"2006","journal-title":"Thromb Haemost"},{"issue":"5","key":"10.1016\/j.thromres.2013.07.022_bb0135","doi-asserted-by":"crossref","first-page":"756","DOI":"10.1160\/TH06-03-0162","article-title":"Age-dependency of thrombin generation","volume":"95","author":"Hemker","year":"2006","journal-title":"Thromb Haemost"},{"issue":"5","key":"10.1016\/j.thromres.2013.07.022_bb0140","doi-asserted-by":"crossref","first-page":"772","DOI":"10.1160\/TH05-10-0685","article-title":"Age-dependency of thrombin generation measured by means of calibrated automated thrombography (CAT)","volume":"95","author":"Haidl","year":"2006","journal-title":"Thromb Haemost"},{"issue":"2","key":"10.1016\/j.thromres.2013.07.022_bb0145","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1016\/j.preghy.2012.01.004","article-title":"Coagulation and Fibrinolytic System Protein Profiles in Women with Normal Pregnancies and Pregnancies Complicated by Hypertension","volume":"2","author":"Hale","year":"2012","journal-title":"Pregnancy Hypertens"},{"issue":"2","key":"10.1016\/j.thromres.2013.07.022_bb0150","doi-asserted-by":"crossref","first-page":"173","DOI":"10.3109\/00365513.2010.545432","article-title":"Changes in fibrin D-dimer, fibrinogen, and protein S during pregnancy","volume":"71","author":"Hansen","year":"2011","journal-title":"Scand J Clin Lab Invest"},{"issue":"3","key":"10.1016\/j.thromres.2013.07.022_bb0155","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1016\/S0049-3848(02)00022-1","article-title":"Plasma and serum levels of D-dimer and their correlations with other hemostatic parameters in pregnancy","volume":"105","author":"Paniccia","year":"2002","journal-title":"Thromb Res"},{"issue":"3","key":"10.1016\/j.thromres.2013.07.022_bb0160","doi-asserted-by":"crossref","first-page":"e171","DOI":"10.1016\/j.thromres.2012.05.022","article-title":"D-Dimer levels at different stages of pregnancy in Australian women: a single centre study using two different immunoturbidimetric assays","volume":"130","author":"Khalafallah","year":"2012","journal-title":"Thromb Res"},{"issue":"1","key":"10.1016\/j.thromres.2013.07.022_bb0165","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/j.ejogrb.2009.09.005","article-title":"The use of D-dimer with new cutoff can be useful in diagnosis of venous thromboembolism in pregnancy","volume":"148","author":"Kovac","year":"2010","journal-title":"Eur J Obstet Gynecol Reprod Biol"},{"issue":"4","key":"10.1016\/j.thromres.2013.07.022_bb0170","doi-asserted-by":"crossref","first-page":"689","DOI":"10.1111\/j.1447-0756.2008.01007.x","article-title":"Evaluation of D-dimer during pregnancy","volume":"35","author":"Nishii","year":"2009","journal-title":"J Obstet Gynaecol Res"},{"issue":"6","key":"10.1016\/j.thromres.2013.07.022_bb0175","doi-asserted-by":"crossref","first-page":"691","DOI":"10.1016\/0049-3848(82)90007-X","article-title":"Evaluation of the soluble fibrin monomer complexes and other coagulation parameters in obstetric patients","volume":"27","author":"Aznar","year":"1982","journal-title":"Thromb Res"},{"issue":"2","key":"10.1016\/j.thromres.2013.07.022_bb0180","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1159\/000299013","article-title":"Soluble fibrin monomer complexes and other hemostatic parameters in patients with intrauterine fetal death","volume":"19","author":"Gilabert","year":"1985","journal-title":"Gynecol Obstet Invest"},{"issue":"4","key":"10.1016\/j.thromres.2013.07.022_bb0185","doi-asserted-by":"crossref","first-page":"767","DOI":"10.1160\/TH07-09-0581","article-title":"Influence of coagulation factors and tissue factor concentration on the thrombin generation test in plasma","volume":"99","author":"Duchemin","year":"2008","journal-title":"Thromb Haemost"},{"issue":"9","key":"10.1016\/j.thromres.2013.07.022_bb0190","doi-asserted-by":"crossref","first-page":"1563","DOI":"10.3324\/haematol.2010.021923","article-title":"Similar hypercoagulable state and thrombosis risk in type I and type III protein S-deficient individuals from families with mixed type I\/III protein S deficiency","volume":"95","author":"Castoldi","year":"2010","journal-title":"Haematologica"},{"issue":"1","key":"10.1016\/j.thromres.2013.07.022_bb0195","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1111\/j.1538-7836.2007.02824.x","article-title":"Coagulation factors and the protein C system as determinants of thrombin generation in a normal population","volume":"6","author":"Dielis","year":"2008","journal-title":"J Thromb Haemost"},{"issue":"5","key":"10.1016\/j.thromres.2013.07.022_bb0200","doi-asserted-by":"crossref","first-page":"775","DOI":"10.1016\/j.thromres.2011.12.023","article-title":"The effect of total hip\/knee replacement surgery and prophylactic dabigatran on thrombin generation and coagulation parameters","volume":"130","author":"Green","year":"2012","journal-title":"Thromb Res"},{"issue":"1","key":"10.1016\/j.thromres.2013.07.022_bb0205","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1055\/s-0037-1613145","article-title":"Effects of hereditary and acquired risk factors of venous thrombosis on a thrombin generation-based APC resistance test","volume":"88","author":"Curvers","year":"2002","journal-title":"Thromb Haemost"},{"issue":"5","key":"10.1016\/j.thromres.2013.07.022_bb0210","first-page":"562","article-title":"Use of calibrated automated thrombinography +\/- thrombomodulin to recognise the prothrombotic phenotype","volume":"96","author":"Dargaud","year":"2006","journal-title":"Thromb Haemost"},{"issue":"4","key":"10.1016\/j.thromres.2013.07.022_bb0215","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1016\/j.thromres.2009.11.012","article-title":"Standardisation of thrombin generation test\u2013which reference plasma for TGT? An international multicentre study","volume":"125","author":"Dargaud","year":"2010","journal-title":"Thromb Res"},{"issue":"2","key":"10.1016\/j.thromres.2013.07.022_bb0220","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1111\/j.1365-2141.2007.06785.x","article-title":"Effect of standardization and normalization on imprecision of calibrated automated thrombography: an international multicentre study","volume":"139","author":"Dargaud","year":"2007","journal-title":"Br J Haematol"},{"issue":"6","key":"10.1016\/j.thromres.2013.07.022_bb0225","doi-asserted-by":"crossref","first-page":"929","DOI":"10.1016\/j.thromres.2012.07.017","article-title":"Evaluation of a standardized protocol for thrombin generation measurement using the calibrated automated thrombogram: An international multicentre study","volume":"130","author":"Dargaud","year":"2012","journal-title":"Thromb Res"},{"issue":"2","key":"10.1016\/j.thromres.2013.07.022_bb0230","doi-asserted-by":"crossref","first-page":"350","DOI":"10.1160\/TH07-05-0357","article-title":"Thrombin generation assays are superior to traditional tests in assessing anticoagulation reversal in vitro","volume":"100","author":"Gatt","year":"2008","journal-title":"Thromb Haemost"},{"issue":"6","key":"10.1016\/j.thromres.2013.07.022_bb0235","doi-asserted-by":"crossref","first-page":"1165","DOI":"10.1160\/TH12-05-0350","article-title":"Differential haemostatic risk factors for pregnancy-related deep-vein thrombosis and pulmonary embolism. A population-based case-control study","volume":"108","author":"Bergrem","year":"2012","journal-title":"Thromb Haemost"}],"container-title":["Thrombosis Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0049384813003253?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0049384813003253?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,7,20]],"date-time":"2019-07-20T07:23:15Z","timestamp":1563607395000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0049384813003253"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,9]]},"references-count":47,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2013,9]]}},"alternative-id":["S0049384813003253"],"URL":"https:\/\/doi.org\/10.1016\/j.thromres.2013.07.022","relation":{},"ISSN":["0049-3848"],"issn-type":[{"value":"0049-3848","type":"print"}],"subject":[],"published":{"date-parts":[[2013,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Comparison of markers of coagulation activation and thrombin generation test in uncomplicated pregnancies","name":"articletitle","label":"Article Title"},{"value":"Thrombosis Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.thromres.2013.07.022","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2013 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}