{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T05:00:37Z","timestamp":1761541237769},"reference-count":26,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2015,5,1]],"date-time":"2015-05-01T00:00:00Z","timestamp":1430438400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.com","thrombosisresearch.com","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Thrombosis Research"],"published-print":{"date-parts":[[2015,5]]},"DOI":"10.1016\/j.thromres.2015.02.010","type":"journal-article","created":{"date-parts":[[2015,2,19]],"date-time":"2015-02-19T01:36:41Z","timestamp":1424309801000},"page":"823-828","update-policy":"http:\/\/dx.doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":18,"title":["Factors associated with the platelet count in patients with chronic hepatitis C"],"prefix":"10.1016","volume":"135","author":[{"given":"Michele M.","family":"Tana","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiongce","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alyson","family":"Bradshaw","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mi Sun","family":"Moon","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sandy","family":"Page","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tiffany","family":"Turner","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elenita","family":"Rivera","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David E.","family":"Kleiner","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Theo","family":"Heller","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.thromres.2015.02.010_bb0005","doi-asserted-by":"crossref","DOI":"10.3111\/13696998.2011.562266","article-title":"Medical resource utilisation and healthcare costs in patients with chronic hepatitis C viral infection and thrombocytopenia","volume":"14","author":"Poordad","year":"2011","journal-title":"J Med Econ"},{"key":"10.1016\/j.thromres.2015.02.010_bb0010","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1186\/1756-0500-5-142","article-title":"Trends in the prevalence of thrombocytopenia among individuals infected with hepatitis C virus in the United States, 1999-2008","volume":"5","author":"Kauf","year":"2012","journal-title":"BMC Res Notes"},{"key":"10.1016\/j.thromres.2015.02.010_bb0015","doi-asserted-by":"crossref","DOI":"10.1111\/j.1365-2893.2010.01366.x","article-title":"Prevalence of thrombocytopenia among patients with chronic hepatitis C: a systematic review","volume":"18","author":"Louie","year":"2011","journal-title":"J Viral Hepat"},{"key":"10.1016\/j.thromres.2015.02.010_bb0020","doi-asserted-by":"crossref","first-page":"887","DOI":"10.1111\/apt.12273","article-title":"Long-term outcome of chronic hepatitis C after sustained virological response to interferon-based therapy","volume":"37","author":"Koh","year":"2013","journal-title":"Aliment Pharmacol Ther"},{"key":"10.1016\/j.thromres.2015.02.010_bb0025","doi-asserted-by":"crossref","first-page":"807","DOI":"10.7326\/0003-4819-158-11-201306040-00005","article-title":"Blood tests to diagnose fibrosis or cirrhosis in patients with chronic hepatitis C virus infection: a systematic review","volume":"158","author":"Chou","year":"2013","journal-title":"Ann Intern Med"},{"key":"10.1016\/j.thromres.2015.02.010_bb0030","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1093\/cid\/cit245","article-title":"Investigators CHCSC: Noninvasive serum fibrosis markers for screening and staging chronic hepatitis C virus patients in a large US cohort","volume":"57","author":"Holmberg","year":"2013","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.thromres.2015.02.010_bb0035","doi-asserted-by":"crossref","first-page":"832","DOI":"10.1001\/jama.2012.186","article-title":"Does this patient with liver disease have cirrhosis?","volume":"307","author":"Udell","year":"2012","journal-title":"JAMA"},{"key":"10.1016\/j.thromres.2015.02.010_bb0040","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1053\/j.gastro.2012.10.001","article-title":"Elastography, spleen size, and platelet count identify portal hypertension in patients with compensated cirrhosis","volume":"144","author":"Berzigotti","year":"2013","journal-title":"Gastroenterology"},{"key":"10.1016\/j.thromres.2015.02.010_bb0045","first-page":"381","article-title":"Thrombocytopenia in chronic hepatitis C","volume":"19","author":"Olariu","year":"2010","journal-title":"J Gastrointestin Liver Dis"},{"key":"10.1016\/j.thromres.2015.02.010_bb0050","doi-asserted-by":"crossref","DOI":"10.1177\/1076029611429124","article-title":"Causes of Thrombocytopenia in Chronic Hepatitis C Viral Infection","volume":"18","author":"Osada","year":"2012","journal-title":"Clin Appl Thromb Hemost"},{"key":"10.1016\/j.thromres.2015.02.010_bb0055","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1179\/102453309X439818","article-title":"Antiplatelet antibodies contribute to thrombocytopenia associated with chronic hepatitis C virus infection","volume":"14","author":"Aref","year":"2009","journal-title":"Hematology"},{"key":"10.1016\/j.thromres.2015.02.010_bb0060","doi-asserted-by":"crossref","first-page":"778","DOI":"10.1111\/bjh.12328","article-title":"Advances in megakaryocytopoiesis and thrombopoiesis: from bench to bedside","volume":"161","author":"Deutsch","year":"2013","journal-title":"Br J Haematol"},{"key":"10.1016\/j.thromres.2015.02.010_bb0065","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1007\/s12185-013-1382-0","article-title":"The biology of thrombopoietin and thrombopoietin receptor agonists","volume":"98","author":"Kuter","year":"2013","journal-title":"Int J Hematol"},{"key":"10.1016\/j.thromres.2015.02.010_bb0070","doi-asserted-by":"crossref","first-page":"2516","DOI":"10.1111\/j.1572-0241.2003.08665.x","article-title":"Relationship between thrombopoietin serum levels and liver function in patients with chronic liver disease related to hepatitis C virus infection","volume":"98","author":"Giannini","year":"2003","journal-title":"Am J Gastroenterol"},{"key":"10.1016\/j.thromres.2015.02.010_bb0075","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1111\/j.1751-553X.2012.01429.x","article-title":"Mechanism of thrombocytopenia in chronic hepatitis C as evaluated by the immature platelet fraction","volume":"34","author":"Zucker","year":"2012","journal-title":"Int J Lab Hematol"},{"key":"10.1016\/j.thromres.2015.02.010_bb0080","doi-asserted-by":"crossref","first-page":"638","DOI":"10.1046\/j.1440-1746.2003.03026.x","article-title":"Role of elevated platelet-associated immunoglobulin G and hypersplenism in thrombocytopenia of chronic liver diseases","volume":"18","author":"Sanjo","year":"2003","journal-title":"J Gastroenterol Hepatol"},{"key":"10.1016\/j.thromres.2015.02.010_bb0085","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1053\/j.gastro.2012.09.056","article-title":"Characteristics of congenital hepatic fibrosis in a large cohort of patients with autosomal recessive polycystic kidney disease","volume":"144","author":"Gunay-Aygun","year":"2013","journal-title":"Gastroenterology"},{"key":"10.1016\/j.thromres.2015.02.010_bb0090","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1111\/j.0902-4441.2006.t01-1-EJH2888.x","article-title":"Platelet autoantibodies are common in hepatitis C infection,irrespective of the presence of thrombocytopenia","volume":"77","author":"Panzer","year":"2006","journal-title":"Eur J Haematol"},{"key":"10.1016\/j.thromres.2015.02.010_bb0095","doi-asserted-by":"crossref","first-page":"894","DOI":"10.1016\/j.jhep.2010.08.018","article-title":"Platelet production and destruction in liver cirrhosis","volume":"54","author":"Pradella","year":"2011","journal-title":"J Hepatol"},{"key":"10.1016\/j.thromres.2015.02.010_bb0100","doi-asserted-by":"crossref","first-page":"1624","DOI":"10.1111\/j.1538-7836.2012.04800.x","article-title":"The circulating platelet count is not dictated by the liver, but may be determined in part by the bone marrow: analyses from human liver and stem cell transplantations","volume":"10","author":"Lisman","year":"2012","journal-title":"J Thromb Haemost"},{"key":"10.1016\/j.thromres.2015.02.010_bb0105","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1007\/s10620-012-2450-7","article-title":"Thrombocytopenia in patients with chronic liver disease: what's in a name?","volume":"58","author":"Giannini","year":"2013","journal-title":"Dig Dis Sci"},{"key":"10.1016\/j.thromres.2015.02.010_bb0110","first-page":"431","article-title":"Platelet count\/spleen diameter ratio to predict the presence of esophageal varices in patients with cirrhosis: a systematic review","volume":"24","author":"Chawla","year":"2012","journal-title":"Eur J Gastroenterol Hepatol"},{"key":"10.1016\/j.thromres.2015.02.010_bb0115","doi-asserted-by":"crossref","first-page":"1672","DOI":"10.1007\/s10620-012-2058-y","article-title":"Performance of platelet count\/spleen diameter ratio for diagnosis of esophageal varices in cirrhosis: a meta-analysis","volume":"57","author":"Ying","year":"2012","journal-title":"Dig Dis Sci"},{"key":"10.1016\/j.thromres.2015.02.010_bb0120","doi-asserted-by":"crossref","first-page":"504","DOI":"10.1016\/j.dld.2011.12.016","article-title":"Platelet count\/spleen diameter ratio for non-invasive diagnosis of oesophageal varices: is it useful in compensated cirrhosis?","volume":"44","author":"Mangone","year":"2012","journal-title":"Dig Liver Dis"},{"key":"10.1016\/j.thromres.2015.02.010_bb0125","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1016\/j.thromres.2005.09.007","article-title":"A simple technique to determine thrombopoiesis level using immature platelet fraction (IPF)","volume":"118","author":"Abe","year":"2006","journal-title":"Thromb Res"},{"key":"10.1016\/j.thromres.2015.02.010_bb0130","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1038\/nm.3770","article-title":"The Ashwell-Morell receptor regulates hepatic thrombopoietin production via JAK2-STAT3 signaling","volume":"21","author":"Grozovsky","year":"2015","journal-title":"Nat Med"}],"container-title":["Thrombosis Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0049384815000651?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0049384815000651?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,9,25]],"date-time":"2018-09-25T01:52:10Z","timestamp":1537840330000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0049384815000651"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,5]]},"references-count":26,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2015,5]]}},"alternative-id":["S0049384815000651"],"URL":"https:\/\/doi.org\/10.1016\/j.thromres.2015.02.010","relation":{},"ISSN":["0049-3848"],"issn-type":[{"value":"0049-3848","type":"print"}],"subject":[],"published":{"date-parts":[[2015,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Factors associated with the platelet count in patients with chronic hepatitis C","name":"articletitle","label":"Article Title"},{"value":"Thrombosis Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.thromres.2015.02.010","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2015 Elsevier Ltd. Published by Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}