{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T07:05:09Z","timestamp":1789110309267,"version":"build-2803163510"},"reference-count":20,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2021,5,1]],"date-time":"2021-05-01T00:00:00Z","timestamp":1619827200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,5,1]],"date-time":"2021-05-01T00:00:00Z","timestamp":1619827200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,5,1]],"date-time":"2021-05-01T00:00:00Z","timestamp":1619827200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2021,5,1]],"date-time":"2021-05-01T00:00:00Z","timestamp":1619827200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2021,5,1]],"date-time":"2021-05-01T00:00:00Z","timestamp":1619827200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2021,5,1]],"date-time":"2021-05-01T00:00:00Z","timestamp":1619827200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2021,5,1]],"date-time":"2021-05-01T00:00:00Z","timestamp":1619827200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001700","name":"Ministry of Education, Culture, Sports, Science and Technology","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001700","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003478","name":"Ministry of Health, Labour and Welfare","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003478","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","thrombosisresearch.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Thrombosis Research"],"published-print":{"date-parts":[[2021,5]]},"DOI":"10.1016\/j.thromres.2021.03.030","type":"journal-article","created":{"date-parts":[[2021,4,9]],"date-time":"2021-04-09T02:19:08Z","timestamp":1617934748000},"page":"154-160","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":12,"special_numbering":"C","title":["Evaluation of hemostatic abnormalities in patients who underwent major hepatobiliary pancreatic surgery using activated partial thromboplastin time-clot waveform analysis"],"prefix":"10.1016","volume":"201","author":[{"given":"Koki","family":"Maeda","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hideo","family":"Wada","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Toru","family":"Shinkai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akihiro","family":"Tanemura","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takeshi","family":"Matsumoto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shugo","family":"Mizuno","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.thromres.2021.03.030_bb0005","doi-asserted-by":"crossref","first-page":"252","DOI":"10.1002\/jhbp.444","article-title":"Safety-related outcomes of the Japanese Society of Hepato-Biliary-Pancreatic Surgery board certification system for expert surgeons","volume":"24","author":"Otsubo","year":"2017","journal-title":"J. Hepatobiliary. Pancreat. Sci."},{"key":"10.1016\/j.thromres.2021.03.030_bb0010","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1097\/01.sla.0000151794.28392.a6","article-title":"High incidence of thrombosis of the portal venous system after laparoscopic splenectomy: a prospective study with contrast-enhanced CT scan","volume":"241","author":"Ikeda","year":"2005","journal-title":"Ann. Surg."},{"key":"10.1016\/j.thromres.2021.03.030_bb0015","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1097\/01.sla.0000262953.77735.db","article-title":"Postpancreatectomy hemorrhage: diagnosis and treatment - an analysis in 1669 consecutive pancreatic resections","volume":"246","author":"Yekebas","year":"2007","journal-title":"Ann. Surg."},{"key":"10.1016\/j.thromres.2021.03.030_bb0020","doi-asserted-by":"crossref","first-page":"1491","DOI":"10.1007\/s00268-013-2440-8","article-title":"Portal vein thrombosis after hepatectomy","volume":"38","author":"Yoshiya","year":"2014","journal-title":"World J. Surg."},{"key":"10.1016\/j.thromres.2021.03.030_bb0025","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1007\/s12185-016-2108-x","article-title":"A combined approach using global coagulation assays quickly differentiates coagulation disorders with prolonged aPTT and low levels of FVIII activity","volume":"105","author":"Matsumoto","year":"2017","journal-title":"Int. J. Hematol."},{"key":"10.1016\/j.thromres.2021.03.030_bb0030","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1111\/ijlh.12635","article-title":"Clot wave analysis and thromboembolic score in liver cirrhosis: two opposing phenomena","volume":"39","author":"Ruberto","year":"2017","journal-title":"Int. J. Lab. Hematol."},{"key":"10.1016\/j.thromres.2021.03.030_bb0035","doi-asserted-by":"crossref","unstructured":"H. Wada, T. Matsumoto, K. Ohishi, K. Shiraki, M. Shimaoka, Update on the clot waveform analysis, Clin. Appl. Thromb. 26 (2020). doi:https:\/\/doi.org\/10.1177\/1076029620912027.","DOI":"10.1177\/1076029620912027"},{"key":"10.1016\/j.thromres.2021.03.030_bb0040","doi-asserted-by":"crossref","first-page":"1654","DOI":"10.1097\/01.CCM.0000217471.12799.1C","article-title":"Activated partial thromboplastin time waveform analysis: a new tool to detect infection?","volume":"34","author":"Chopin","year":"2006","journal-title":"Crit. Care Med."},{"key":"10.1016\/j.thromres.2021.03.030_bb0045","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1177\/107602960601200206","article-title":"Frequency of abnormal biphasic aPTT clot waveforms in patients with underlying disorders associated with disseminated intravascular coagulation","volume":"12","author":"Matsumoto","year":"2006","journal-title":"Clin. Appl. Thromb."},{"key":"10.1016\/j.thromres.2021.03.030_bb0050","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1046\/j.1365-2257.2002.00457.x","article-title":"Waveform analysis of clotting test optical profiles in the diagnosis and management of disseminated intravascular coagulation (DIC)","volume":"24","author":"Toh","year":"2002","journal-title":"Clin. Lab. Haematol."},{"key":"10.1016\/j.thromres.2021.03.030_bb0055","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1111\/j.1751-553X.2010.01248.x","article-title":"A study of atypical APTT derivative curves on the ACL TOP coagulation analyser","volume":"33","author":"Solano","year":"2011","journal-title":"Int. J. Lab. Hematol."},{"key":"10.1016\/j.thromres.2021.03.030_bb0060","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1097\/MBC.0000000000000436","article-title":"Usefulness of the second-derivative curve of activated partial thromboplastin time on the ACL-TOP coagulation analyzer for detecting factor deficiencies","volume":"27","author":"Tokunaga","year":"2016","journal-title":"Blood Coagul. Fibrinolysis"},{"key":"10.1016\/j.thromres.2021.03.030_bb0065","first-page":"1","article-title":"Assessment of aPTT-based clot waveform analysis for the detection of haemostatic changes in different types of infections","volume":"10","author":"Tan","year":"2020","journal-title":"Sci. Rep."},{"key":"10.1016\/j.thromres.2021.03.030_bb0070","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1111\/ijlh.12727","article-title":"Monitoring of hemostatic abnormalities in major orthopedic surgery patients treated with edoxaban by APTT waveform","volume":"40","author":"Hasegawa","year":"2018","journal-title":"Int. J. Lab. Hematol."},{"key":"10.1016\/j.thromres.2021.03.030_bb0075","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1111\/j.1538-7836.2009.03678.x","article-title":"Definition of major bleeding in clinical investigations of antihemostatic medicinal products in surgical patients","volume":"8","author":"Schulman","year":"2010","journal-title":"J. Thromb. Haemost."},{"key":"10.1016\/j.thromres.2021.03.030_bb0080","doi-asserted-by":"crossref","first-page":"923","DOI":"10.1097\/01.sla.0000251747.80025.b7","article-title":"Hepatic steatosis is a risk factor for postoperative complications after major hepatectomy: a matched case-control study","volume":"245","author":"McCormack","year":"2007","journal-title":"Ann. Surg."},{"key":"10.1016\/j.thromres.2021.03.030_bb0085","doi-asserted-by":"crossref","first-page":"608","DOI":"10.1097\/EJA.0b013e328334df31","article-title":"Thromboelastographic changes in liver and pancreatic cancer surgery: hypercoagulability, hypocoagulability or normocoagulability?","volume":"27","author":"De Pietri","year":"2010","journal-title":"Eur. J. Anaesthesiol."},{"key":"10.1016\/j.thromres.2021.03.030_bb0090","doi-asserted-by":"crossref","first-page":"765","DOI":"10.1016\/S0020-1383(01)00139-5","article-title":"Changes in coagulability as measured by thrombelastography following surgery for proximal femoral fracture","volume":"32","author":"Wilson","year":"2001","journal-title":"Injury."},{"key":"10.1016\/j.thromres.2021.03.030_bb0095","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s12959-019-0201-0","article-title":"Usefulness of the APTT waveform for the diagnosis of DIC and prediction of the outcome or bleeding risk","volume":"17","author":"Suzuki","year":"2019","journal-title":"Thromb. J."},{"key":"10.1016\/j.thromres.2021.03.030_bb0100","doi-asserted-by":"crossref","first-page":"1170","DOI":"10.1177\/1076029618757344","article-title":"An evaluation of hemostatic abnormalities in patients with hemophilia according to the activated partial thromboplastin time waveform","volume":"24","author":"Katayama","year":"2018","journal-title":"Clin. Appl. Thromb."}],"container-title":["Thrombosis Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0049384821001341?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0049384821001341?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,24]],"date-time":"2025-09-24T17:45:51Z","timestamp":1758735951000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0049384821001341"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,5]]},"references-count":20,"alternative-id":["S0049384821001341"],"URL":"https:\/\/doi.org\/10.1016\/j.thromres.2021.03.030","relation":{},"ISSN":["0049-3848"],"issn-type":[{"value":"0049-3848","type":"print"}],"subject":[],"published":{"date-parts":[[2021,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Evaluation of hemostatic abnormalities in patients who underwent major hepatobiliary pancreatic surgery using activated partial thromboplastin time-clot waveform analysis","name":"articletitle","label":"Article Title"},{"value":"Thrombosis Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.thromres.2021.03.030","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}