{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,10]],"date-time":"2026-04-10T03:27:10Z","timestamp":1775791630971,"version":"3.50.1"},"reference-count":34,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2022,1,1]],"date-time":"2022-01-01T00:00:00Z","timestamp":1640995200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,1,1]],"date-time":"2022-01-01T00:00:00Z","timestamp":1640995200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,1,1]],"date-time":"2022-01-01T00:00:00Z","timestamp":1640995200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2022,1,1]],"date-time":"2022-01-01T00:00:00Z","timestamp":1640995200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2022,1,1]],"date-time":"2022-01-01T00:00:00Z","timestamp":1640995200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2022,1,1]],"date-time":"2022-01-01T00:00:00Z","timestamp":1640995200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2022,1,1]],"date-time":"2022-01-01T00:00:00Z","timestamp":1640995200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","thrombosisresearch.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Thrombosis Research"],"published-print":{"date-parts":[[2022,1]]},"DOI":"10.1016\/j.thromres.2021.11.005","type":"journal-article","created":{"date-parts":[[2021,11,22]],"date-time":"2021-11-22T11:04:51Z","timestamp":1637579091000},"page":"41-46","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":9,"special_numbering":"C","title":["Splanchnic vein thrombosis-related mortality in the Veneto region (Italy), 2008\u20132019: Retrospective analysis of epidemiological data"],"prefix":"10.1016","volume":"209","author":[{"given":"Giacomo","family":"Turatti","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ugo","family":"Fedeli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luca","family":"Valerio","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Frederikus A.","family":"Klok","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alexander T.","family":"Cohen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Beverley J.","family":"Hunt","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paolo","family":"Simioni","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Saskia","family":"Middeldorp","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Walter","family":"Ageno","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nils","family":"Kucher","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stavros V.","family":"Konstantinides","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elena","family":"Schievano","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2618-347X","authenticated-orcid":false,"given":"Stefano","family":"Barco","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.thromres.2021.11.005_bb0005","doi-asserted-by":"crossref","first-page":"1154","DOI":"10.1111\/j.1365-2036.2010.04454.x","article-title":"The epidemiology and clinical features of portal vein thrombosis: a multicentre study","volume":"32","author":"Rajani","year":"2010","journal-title":"Aliment. Pharmacol. Ther."},{"key":"10.1016\/j.thromres.2021.11.005_bb0010","doi-asserted-by":"crossref","first-page":"1245","DOI":"10.1002\/bjs.6319","article-title":"Epidemiology, risk and prognostic factors in mesenteric venous thrombosis","volume":"95","author":"Acosta","year":"2008","journal-title":"Br. J. Surg."},{"key":"10.1016\/j.thromres.2021.11.005_bb0015","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.thromres.2016.02.024","article-title":"Survival after splanchnic vein thrombosis: a 20-year nationwide cohort study","volume":"141","author":"Sogaard","year":"2016","journal-title":"Thromb. Res."},{"key":"10.1016\/j.thromres.2021.11.005_bb0020","article-title":"Incidence rates and case fatality rates of portal vein thrombosis and Budd-Chiari syndrome","volume":"117","author":"Ageno","year":"2017","journal-title":"Thromb. Haemost."},{"key":"10.1016\/j.thromres.2021.11.005_bb0025","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1111\/j.1478-3231.2008.01838.x","article-title":"Budd-Chiari syndrome in Sweden: epidemiology, clinical characteristics and survival - an 18-year experience","volume":"29","author":"Rajani","year":"2009","journal-title":"Liver Int."},{"key":"10.1016\/j.thromres.2021.11.005_bb0030","doi-asserted-by":"crossref","first-page":"745","DOI":"10.1097\/00042737-200507000-00009","article-title":"Causes of portal venous thrombosis in cirrhotic patients: the role of genetic and acquired factors","volume":"17","author":"Mangia","year":"2005","journal-title":"Eur. J. Gastroenterol. Hepatol."},{"key":"10.1016\/j.thromres.2021.11.005_bb0035","doi-asserted-by":"crossref","first-page":"682","DOI":"10.1016\/j.jhep.2009.03.013","article-title":"Thrombotic risk factors in patients with liver cirrhosis: correlation with MELD scoring system and portal vein thrombosis development","volume":"51","author":"Zocco","year":"2009","journal-title":"J. Hepatol."},{"key":"10.1016\/j.thromres.2021.11.005_bb0040","doi-asserted-by":"crossref","first-page":"1879","DOI":"10.1111\/j.1538-7836.2010.03929.x","article-title":"High rates of symptomatic and incidental thromboembolic events in gastrointestinal cancer patients","volume":"8","author":"Singh","year":"2010","journal-title":"J. Thromb. Haemost."},{"key":"10.1016\/j.thromres.2021.11.005_bb0045","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1016\/j.thromres.2019.11.023","article-title":"Splanchnic vein thrombosis predicts worse survival in patients with advanced pancreatic cancer","volume":"185","author":"Afzal","year":"2020","journal-title":"Thromb. Res."},{"key":"10.1016\/j.thromres.2021.11.005_bb0050","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1111\/j.1600-0609.2006.00715.x","article-title":"Abdominal vein thrombosis in essential thrombocythemia: prevalence, clinical correlates, and prognostic implications","volume":"77","author":"Gangat","year":"2006","journal-title":"Eur. J. Haematol."},{"key":"10.1016\/j.thromres.2021.11.005_bb0055","doi-asserted-by":"crossref","first-page":"791","DOI":"10.1007\/s00277-020-03965-z","article-title":"Natural history of polycythemia vera and essential thrombocythemia presenting with splanchnic vein thrombosis","volume":"99","author":"Alvarez-Larran","year":"2020","journal-title":"Ann. Hematol."},{"key":"10.1016\/j.thromres.2021.11.005_bb0060","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1016\/j.cgh.2009.09.019","article-title":"Survival and recurrence in patients with splanchnic vein thromboses","volume":"8","author":"Thatipelli","year":"2010","journal-title":"Clin. Gastroenterol. Hepatol."},{"key":"10.1016\/j.thromres.2021.11.005_bb0065","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1038\/s41424-018-0043-2","article-title":"Long-term outcome of splanchnic vein thrombosis in cirrhosis","volume":"9","author":"Senzolo","year":"2018","journal-title":"Clin. Transl. Gastroenterol."},{"key":"10.1016\/j.thromres.2021.11.005_bb0070","doi-asserted-by":"crossref","first-page":"2464","DOI":"10.1111\/j.1572-0241.2007.01477.x","article-title":"Prognostic factors in noncirrhotic patients with splanchnic vein thromboses","volume":"102","author":"Amitrano","year":"2007","journal-title":"Am. J. Gastroenterol."},{"key":"10.1016\/j.thromres.2021.11.005_bb0075","doi-asserted-by":"crossref","first-page":"e267","DOI":"10.1016\/S2352-3026(16)30020-5","article-title":"Clinical history and antithrombotic treatment of incidentally detected splanchnic vein thrombosis: a multicentre, international prospective registry","volume":"3","author":"Riva","year":"2016","journal-title":"Lancet Haematol."},{"key":"10.1016\/j.thromres.2021.11.005_bb0080","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1111\/j.1538-7836.2011.04565.x","article-title":"Incidental diagnosis of a deep vein thrombosis in consecutive patients undergoing a computed tomography scan of the abdomen: a retrospective cohort study","volume":"10","author":"Ageno","year":"2012","journal-title":"J. Thromb. Haemost."},{"key":"10.1016\/j.thromres.2021.11.005_bb0085","doi-asserted-by":"crossref","DOI":"10.1016\/j.jss.2019.07.086","article-title":"Incidence of splanchnic vein thrombosis after abdominal surgery: a systematic review and meta-analysis","volume":"245","author":"Zhang","year":"2020","journal-title":"J. Surg. Res."},{"key":"10.1016\/j.thromres.2021.11.005_bb0090","doi-asserted-by":"crossref","first-page":"2115","DOI":"10.3748\/wjg.v12.i13.2115","article-title":"Portal vein thrombosis: prevalence, patient characteristics and lifetime risk: a population study based on 23,796 consecutive autopsies","volume":"12","author":"Ogren","year":"2006","journal-title":"World J. Gastroenterol."},{"key":"10.1016\/j.thromres.2021.11.005_bb0095","doi-asserted-by":"crossref","DOI":"10.1016\/j.aohep.2021.100356","article-title":"COVID-19 vaccine-induced immune thrombotic thrombocytopenia: an emerging cause of splanchnic vein thrombosis","volume":"23","author":"Porres-Aguilar","year":"2021","journal-title":"Ann. Hepatol."},{"key":"10.1016\/j.thromres.2021.11.005_bb0100","doi-asserted-by":"crossref","DOI":"10.1016\/S2468-1253(21)00197-7","article-title":"Portal vein thrombosis associated with ChAdOx1 nCov-19 vaccination","author":"\u00d6cal","year":"2021","journal-title":"Lancet Gastroenterol. Hepatol."},{"key":"10.1016\/j.thromres.2021.11.005_bb0105","doi-asserted-by":"crossref","DOI":"10.1093\/aje\/kwq057","article-title":"Trends in frequency of reporting improper diabetes-related cause-of-death statements on death certificates, 1985\u20132005: an algorithm to identify incorrect causal sequences","volume":"171","author":"Lu","year":"2010","journal-title":"Am. J. Epidemiol."},{"key":"10.1016\/j.thromres.2021.11.005_bb0110","first-page":"161","article-title":"Impact of the implementation of ICD-10 2016 version and Iris software on mortality statistics in Italy","volume":"43","author":"Orsi","year":"2019","journal-title":"Epidemiol. Prev."},{"key":"10.1016\/j.thromres.2021.11.005_bb0115","doi-asserted-by":"crossref","first-page":"791","DOI":"10.1002\/(SICI)1097-0258(19970415)16:7<791::AID-SIM500>3.0.CO;2-#","article-title":"Confidence intervals for directly standardized rates: a method based on the gamma distribution","volume":"16","author":"Fay","year":"1997","journal-title":"Stat. Med."},{"key":"10.1016\/j.thromres.2021.11.005_bb0120","doi-asserted-by":"crossref","DOI":"10.1016\/S2213-2600(20)30417-3","article-title":"Age-sex specific pulmonary embolism-related mortality in the USA and Canada, 2000\u201318: an analysis of the WHO Mortality Database and of the CDC Multiple Cause of Death database","volume":"9","author":"Barco","year":"2021","journal-title":"Lancet Respir. Med."},{"key":"10.1016\/j.thromres.2021.11.005_bb0125","doi-asserted-by":"crossref","first-page":"2092","DOI":"10.1056\/NEJMoa2104840","article-title":"Thrombotic thrombocytopenia after ChAdOx1 nCov-19 vaccination","volume":"384","author":"Greinacher","year":"2021","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.thromres.2021.11.005_bb0130","doi-asserted-by":"crossref","first-page":"2124","DOI":"10.1056\/NEJMoa2104882","article-title":"Thrombosis and thrombocytopenia after ChAdOx1 nCoV-19 vaccination","volume":"384","author":"Schultz","year":"2021","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.thromres.2021.11.005_bb0135","doi-asserted-by":"crossref","DOI":"10.1056\/NEJMoa2109908","article-title":"Clinical features of vaccine-induced immune thrombocytopenia and thrombosis","author":"Pavord","year":"2021","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.thromres.2021.11.005_bb0140","doi-asserted-by":"crossref","DOI":"10.1016\/j.heliyon.2019.e02114","article-title":"Prevalence of chronic liver disease among young\/middle-aged adults in Northern Italy: role of hepatitis B and hepatitis C virus infection by age, sex, ethnicity","volume":"5","author":"Fedeli","year":"2019","journal-title":"Heliyon"},{"key":"10.1016\/j.thromres.2021.11.005_bb0145","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1016\/j.amepre.2020.04.024","article-title":"Trends in premature deaths from alcoholic liver disease in the U.S., 1999\u20132018","volume":"59","author":"Yoon","year":"2020","journal-title":"Am. J. Prev. Med."},{"key":"10.1016\/j.thromres.2021.11.005_bb0150","doi-asserted-by":"crossref","first-page":"662","DOI":"10.1093\/alcalc\/agz070","article-title":"Falling rates of hospital admissions for alcoholic liver disease in Northeast Italy: a retrospective study on a large database","volume":"54","author":"Caroli","year":"2019","journal-title":"Alcohol Alcohol."},{"key":"10.1016\/j.thromres.2021.11.005_bb0155","series-title":"Heavy Alcohol Use and Premature Death From Hepatocellular Carcinoma in the United States, 1999-2006*","author":"Dong","year":"2011"},{"key":"10.1016\/j.thromres.2021.11.005_bb0160","doi-asserted-by":"crossref","DOI":"10.1007\/s00406-018-0901-7","article-title":"Alert out on tobacco and alcohol consumption in young European women","volume":"268","author":"Thibaut","year":"2018","journal-title":"Eur. Arch. Psychiatry Clin. Neurosci."},{"key":"10.1016\/j.thromres.2021.11.005_bb0165","article-title":"Examining women's alcohol consumption: the theory of planned behavior and self-identity","volume":"53","author":"Haydon","year":"2018"},{"key":"10.1016\/j.thromres.2021.11.005_bb0170","doi-asserted-by":"crossref","DOI":"10.1016\/S2352-3026(18)30133-9","article-title":"Risk of bleeding and arterial cardiovascular events in patients with splanchnic vein thrombosis in Denmark: a population-based cohort study","volume":"5","author":"S\u00f8gaard","year":"2018","journal-title":"Lancet Haematol."}],"container-title":["Thrombosis Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0049384821005132?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0049384821005132?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,24]],"date-time":"2025-09-24T17:46:23Z","timestamp":1758735983000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0049384821005132"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,1]]},"references-count":34,"alternative-id":["S0049384821005132"],"URL":"https:\/\/doi.org\/10.1016\/j.thromres.2021.11.005","relation":{},"ISSN":["0049-3848"],"issn-type":[{"value":"0049-3848","type":"print"}],"subject":[],"published":{"date-parts":[[2022,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Splanchnic vein thrombosis-related mortality in the Veneto region (Italy), 2008\u20132019: Retrospective analysis of epidemiological data","name":"articletitle","label":"Article Title"},{"value":"Thrombosis Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.thromres.2021.11.005","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}