{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,25]],"date-time":"2025-09-25T00:20:22Z","timestamp":1758759622457,"version":"3.44.0"},"reference-count":28,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2022,5,1]],"date-time":"2022-05-01T00:00:00Z","timestamp":1651363200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,5,1]],"date-time":"2022-05-01T00:00:00Z","timestamp":1651363200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,5,1]],"date-time":"2022-05-01T00:00:00Z","timestamp":1651363200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2022,5,1]],"date-time":"2022-05-01T00:00:00Z","timestamp":1651363200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2022,5,1]],"date-time":"2022-05-01T00:00:00Z","timestamp":1651363200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2022,5,1]],"date-time":"2022-05-01T00:00:00Z","timestamp":1651363200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2022,5,1]],"date-time":"2022-05-01T00:00:00Z","timestamp":1651363200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/100016275","name":"Seoul National University Bundang Hospital","doi-asserted-by":"publisher","award":["16-2017-006"],"award-info":[{"award-number":["16-2017-006"]}],"id":[{"id":"10.13039\/100016275","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","thrombosisresearch.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Thrombosis Research"],"published-print":{"date-parts":[[2022,5]]},"DOI":"10.1016\/j.thromres.2022.03.015","type":"journal-article","created":{"date-parts":[[2022,3,21]],"date-time":"2022-03-21T13:04:54Z","timestamp":1647867894000},"page":"114-118","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"special_numbering":"C","title":["Treatment patterns of thrombopoietin receptor agonists among adults with primary immune thrombocytopenia: A Korean nationwide population-based study"],"prefix":"10.1016","volume":"213","author":[{"given":"Ji Yun","family":"Lee","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ju-Hyun","family":"Lee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sang-A","family":"Kim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Koung Jin","family":"Suh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ji-Won","family":"Kim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Se Hyun","family":"Kim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jeong-Ok","family":"Lee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jin Won","family":"Kim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yu Jung","family":"Kim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Keun-Wook","family":"Lee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jee Hyun","family":"Kim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jong Seok","family":"Lee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Soo-Mee","family":"Bang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"13","key":"10.1016\/j.thromres.2022.03.015_bb0005","doi-asserted-by":"crossref","first-page":"995","DOI":"10.1056\/NEJMra010501","article-title":"Immune thrombocytopenic purpura","volume":"346","author":"Cines","year":"2002","journal-title":"N. Engl. J. Med."},{"issue":"4","key":"10.1016\/j.thromres.2022.03.015_bb0010","doi-asserted-by":"crossref","first-page":"364","DOI":"10.1111\/j.1365-2141.2006.06024.x","article-title":"The pathogenesis of immune thrombocytopaenic purpura","volume":"133","author":"Cooper","year":"2006","journal-title":"Br. J. Haematol."},{"issue":"16","key":"10.1016\/j.thromres.2022.03.015_bb0015","doi-asserted-by":"crossref","first-page":"4190","DOI":"10.1182\/blood-2010-08-302984","article-title":"The American Society of Hematology 2011 evidence-based practice guideline for immune thrombocytopenia","volume":"117","author":"Neunert","year":"2011","journal-title":"Blood"},{"issue":"23","key":"10.1016\/j.thromres.2022.03.015_bb0020","doi-asserted-by":"crossref","first-page":"3829","DOI":"10.1182\/bloodadvances.2019000966","article-title":"American Society of Hematology 2019 guidelines for immune thrombocytopenia","volume":"3","author":"Neunert","year":"2019","journal-title":"Blood Adv."},{"issue":"6","key":"10.1016\/j.thromres.2022.03.015_bb0025","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1002\/ajh.24702","article-title":"Newly diagnosed immune thrombocytopenia adults: clinical epidemiology, exposure to treatments, and evolution.Results of the CARMEN multicenter prospective cohort","volume":"92","author":"Moulis","year":"2017","journal-title":"Am. J. Hematol."},{"issue":"10","key":"10.1016\/j.thromres.2022.03.015_bb0030","article-title":"Treatments for primary immune thrombocytopenia: a review","volume":"11","author":"Samson","year":"2019","journal-title":"Cureus"},{"issue":"2","key":"10.1016\/j.thromres.2022.03.015_bb0035","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1007\/s00277-015-2556-z","article-title":"The use of thrombopoietin-receptor agonists (TPO-RAs) in immune thrombocytopenia (ITP): a \"real life\" retrospective multicenter experience of the Rete Ematologica Pugliese (REP)","volume":"95","author":"Mazza","year":"2016","journal-title":"Ann. Hematol."},{"issue":"7","key":"10.1016\/j.thromres.2022.03.015_bb0040","doi-asserted-by":"crossref","first-page":"1131","DOI":"10.1002\/rth2.12423","article-title":"Second-line treatments and outcomes for immune thrombocytopenia: a retrospective study with electronic health records","volume":"4","author":"Lal","year":"2020","journal-title":"Res. Pract. Thromb. Haemost."},{"issue":"7","key":"10.1016\/j.thromres.2022.03.015_bb0045","doi-asserted-by":"crossref","first-page":"447","DOI":"10.2217\/cer-2019-0177","article-title":"Real-world evidence on clinical outcomes in immune thrombocytopenia treated with thrombopoietin receptor agonists","volume":"9","author":"Forsythe","year":"2020","journal-title":"J. Comp. Eff. Res."},{"issue":"2","key":"10.1016\/j.thromres.2022.03.015_bb0050","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1080\/19371910903070333","article-title":"Introduction: health of the health care system in Korea","volume":"25","author":"Kim","year":"2010","journal-title":"Soc. Work Public Health"},{"issue":"5","key":"10.1016\/j.thromres.2022.03.015_bb0055","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1016\/0021-9681(87)90171-8","article-title":"A new method of classifying prognostic comorbidity in longitudinal studies: development and validation","volume":"40","author":"Charlson","year":"1987","journal-title":"J. Chronic Dis."},{"issue":"9","key":"10.1016\/j.thromres.2022.03.015_bb0060","doi-asserted-by":"crossref","first-page":"1039","DOI":"10.3324\/haematol.2016.146373","article-title":"Immune thrombocytopenia in adults: a prospective cohort study of clinical features and predictors of outcome","volume":"101","author":"Grimaldi-Bensouda","year":"2016","journal-title":"Haematologica"},{"key":"10.1016\/j.thromres.2022.03.015_bb0065","doi-asserted-by":"crossref","first-page":"435","DOI":"10.2147\/CLEP.S229266","article-title":"Treatment patterns among adults with primary immune thrombocytopenia diagnosed in hematology clinics in the United States","volume":"12","author":"McGrath","year":"2020","journal-title":"Clin. Epidemiol."},{"issue":"3","key":"10.1016\/j.thromres.2022.03.015_bb0070","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1111\/j.1600-0609.2005.00602.x","article-title":"Idiopathic thrombocytopenic purpura (ITP) in the elderly: clinical course in 178 patients","volume":"76","author":"Bizzoni","year":"2006","journal-title":"Eur. J. Haematol."},{"issue":"6","key":"10.1016\/j.thromres.2022.03.015_bb0075","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1016\/j.ejim.2007.07.006","article-title":"Idiopathic thrombocytopenic purpura in elderly patients: a study of 47 cases from a single reference center","volume":"19","author":"Daou","year":"2008","journal-title":"Eur. J. Intern. Med."},{"issue":"22","key":"10.1016\/j.thromres.2022.03.015_bb0080","doi-asserted-by":"crossref","first-page":"3308","DOI":"10.1182\/blood-2014-05-578336","article-title":"Epidemiology of incident immune thrombocytopenia: a nationwide population-based study in France","volume":"124","author":"Moulis","year":"2014","journal-title":"Blood"},{"issue":"9 Pt 1","key":"10.1016\/j.thromres.2022.03.015_bb0085","doi-asserted-by":"crossref","first-page":"e426","DOI":"10.1016\/j.lpm.2012.02.010","article-title":"Gender-related analysis of the clinical presentation, treatment response and outcome in patients with immune thrombocytopenia","volume":"41","author":"Andr\u00e8s","year":"2012","journal-title":"Presse Med."},{"issue":"6","key":"10.1016\/j.thromres.2022.03.015_bb0090","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0198504","article-title":"Eltrombopag versus romiplostim in treatment of adult patients with immune thrombocytopenia: a systematic review incorporating an indirect-comparison meta-analysis","volume":"13","author":"Zhang","year":"2018","journal-title":"PLoS One"},{"issue":"3","key":"10.1016\/j.thromres.2022.03.015_bb0095","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1017\/S0266462312000414","article-title":"Romiplostim and eltrombopag for immune thrombocytopenia: methods for indirect comparison","volume":"28","author":"Cooper","year":"2012","journal-title":"Int. J. Technol. Assess. Health Care"},{"issue":"1","key":"10.1016\/j.thromres.2022.03.015_bb0100","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1017\/S0266462313000767","article-title":"Update on romiplostim and eltrombopag indirect comparison","volume":"30","author":"Cooper","year":"2014","journal-title":"Int. J. Technol. Assess. Health Care"},{"issue":"1","key":"10.1016\/j.thromres.2022.03.015_bb0105","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1080\/16078454.2019.1568659","article-title":"Therapeutic options for adult patients with previously treated immune thrombocytopenia - a systematic review and network meta-analysis","volume":"24","author":"Yang","year":"2019","journal-title":"Hematology"},{"issue":"1","key":"10.1016\/j.thromres.2022.03.015_bb0110","doi-asserted-by":"crossref","first-page":"16680","DOI":"10.1038\/s41598-019-53209-y","article-title":"Deciphering predictive factors for choice of thrombopoietin receptor agonist, treatment free responses, and thrombotic events in immune thrombocytopenia","volume":"9","author":"Lozano","year":"2019","journal-title":"Sci. Rep."},{"issue":"9","key":"10.1016\/j.thromres.2022.03.015_bb0115","doi-asserted-by":"crossref","first-page":"1429","DOI":"10.1007\/s00277-016-2738-3","article-title":"Long-term outcome following splenectomy for chronic and persistent immune thrombocytopenia (ITP) in adults and children: splenectomy in ITP","volume":"95","author":"Ahmed","year":"2016","journal-title":"Ann. Hematol."},{"issue":"3","key":"10.1016\/j.thromres.2022.03.015_bb0120","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1111\/ejh.12821","article-title":"Long-term results of splenectomy in adult chronic immune thrombocytopenia","volume":"98","author":"Guan","year":"2017","journal-title":"Eur. J. Haematol."},{"key":"10.1016\/j.thromres.2022.03.015_bb0125","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1016\/j.thromres.2017.05.010","article-title":"Epidemiology and management of primary immune thrombocytopenia: a nationwide population-based study in Korea","volume":"155","author":"Lee","year":"2017","journal-title":"Thromb. Res."},{"issue":"1","key":"10.1016\/j.thromres.2022.03.015_bb0130","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1002\/ajh.25301","article-title":"Systematic literature review of treatments used for adult immune thrombocytopenia in the second-line setting","volume":"94","author":"Bylsma","year":"2019","journal-title":"Am. J. Hematol."},{"key":"10.1016\/j.thromres.2022.03.015_bb0135","doi-asserted-by":"crossref","DOI":"10.1177\/2040620719837906","article-title":"Switching thrombopoietin receptor agonist treatments in patients with primary immune thrombocytopenia","volume":"10","author":"Gonz\u00e1lez-Porras","year":"2019","journal-title":"Ther. Adv. Hematol."},{"issue":"1","key":"10.1016\/j.thromres.2022.03.015_bb0140","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1002\/ajh.24935","article-title":"Alternate use of thrombopoietin receptor agonists in adult primary immune thrombocytopenia patients: a retrospective collaborative survey from Italian hematology centers","volume":"93","author":"Cantoni","year":"2018","journal-title":"Am. J. Hematol."}],"container-title":["Thrombosis Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0049384822001098?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0049384822001098?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,24]],"date-time":"2025-09-24T17:48:06Z","timestamp":1758736086000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0049384822001098"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,5]]},"references-count":28,"alternative-id":["S0049384822001098"],"URL":"https:\/\/doi.org\/10.1016\/j.thromres.2022.03.015","relation":{},"ISSN":["0049-3848"],"issn-type":[{"type":"print","value":"0049-3848"}],"subject":[],"published":{"date-parts":[[2022,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Treatment patterns of thrombopoietin receptor agonists among adults with primary immune thrombocytopenia: A Korean nationwide population-based study","name":"articletitle","label":"Article Title"},{"value":"Thrombosis Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.thromres.2022.03.015","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}