{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T19:40:01Z","timestamp":1787082001969,"version":"build-2736575974"},"reference-count":13,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100004710","name":"Fondazione Umberto Veronesi","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004710","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002426","name":"Fondazione Telethon","doi-asserted-by":"publisher","award":["ggp15063"],"award-info":[{"award-number":["ggp15063"]}],"id":[{"id":"10.13039\/501100002426","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002426","name":"Fondazione Telethon","doi-asserted-by":"publisher","award":["15063"],"award-info":[{"award-number":["15063"]}],"id":[{"id":"10.13039\/501100002426","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","thrombosisresearch.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Thrombosis Research"],"published-print":{"date-parts":[[2023,1]]},"DOI":"10.1016\/j.thromres.2022.11.021","type":"journal-article","created":{"date-parts":[[2022,11,25]],"date-time":"2022-11-25T21:15:38Z","timestamp":1669410938000},"page":"79-82","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":8,"special_numbering":"C","title":["Usefulness of global tests of primary hemostasis in the initial screening of mild\/moderate bleeding disorders for orienting towards von Willebrand disease or inherited platelet functions disorders"],"prefix":"10.1016","volume":"221","author":[{"given":"Andrea","family":"Baccolo","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emanuela","family":"Falcinelli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna Maria","family":"Mezzasoma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giuseppe","family":"Guglielmini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mariachiara","family":"Borghi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Loredana","family":"Bury","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paolo","family":"Gresele","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.thromres.2022.11.021_bb0005","doi-asserted-by":"crossref","DOI":"10.1097\/HS9.0000000000000286","article-title":"Fundamentals for a systematic approach to mild and moderate inherited bleeding disorders: an EHA consensus report","volume":"3","author":"Rodeghiero","year":"2019","journal-title":"Hemasphere"},{"key":"10.1016\/j.thromres.2022.11.021_bb0010","doi-asserted-by":"crossref","first-page":"314","DOI":"10.1111\/jth.12792","article-title":"Subcommittee on platelet physiology of the international society on thrombosis and hemostasis. Diagnosis of inherited platelet function disorders: guidance from the SSC of the ISTH","volume":"13","author":"Gresele","year":"2015","journal-title":"J. Thromb. Haemost."},{"key":"10.1016\/j.thromres.2022.11.021_bb0015","doi-asserted-by":"crossref","first-page":"1562","DOI":"10.1111\/jth.12650","article-title":"Diagnosis of suspected inherited platelet function disorders: results of a worldwide survey","volume":"12","author":"Gresele","year":"2014","journal-title":"J. Thromb. Haemost."},{"key":"10.1016\/j.thromres.2022.11.021_bb0020","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1111\/jth.14363","article-title":"Diagnostic challenges of inherited mild bleeding disorders: a bait for poorly explored clinical and basic research","volume":"17","author":"Mezzano","year":"2019","journal-title":"J. Thromb. Haemost."},{"key":"10.1016\/j.thromres.2022.11.021_bb0025","doi-asserted-by":"crossref","first-page":"2393","DOI":"10.1111\/j.1538-7836.2007.02752.x","article-title":"Usefulness of PFA-100 testing in the diagnostic screening of patients with suspected abnormalities of hemostasis: comparison with the bleeding time","volume":"5","author":"Podda","year":"2007","journal-title":"J. Thromb. Haemost."},{"key":"10.1016\/j.thromres.2022.11.021_bb0030","doi-asserted-by":"crossref","first-page":"1192","DOI":"10.3324\/haematol.2016.160754","article-title":"Bleeding risk of surgery and its prevention in patients with inherited platelet disorders","volume":"102","author":"Orsini","year":"2017","journal-title":"Haematologica"},{"issue":"Suppl 1","key":"10.1016\/j.thromres.2022.11.021_bb0035","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1111\/jth.12248","article-title":"Bleeders, bleeding rates, and bleeding score","volume":"11","author":"Tosetto","year":"2013","journal-title":"J. Thromb. Haemost."},{"key":"10.1016\/j.thromres.2022.11.021_bb0040","doi-asserted-by":"crossref","first-page":"179","DOI":"10.3109\/09537104.2010.543710","article-title":"Incomplete inhibition of platelet function as assessed by the platelet function analyzer (PFA-100) identifies a subset of cardiovascular patients with high residual platelet response while on aspirin","volume":"22","author":"Crescente","year":"2011","journal-title":"Platelets"},{"key":"10.1016\/j.thromres.2022.11.021_bb0045","doi-asserted-by":"crossref","first-page":"1647","DOI":"10.3324\/haematol.11313","article-title":"Laboratory diagnosis and monitoring of desmopressin treatment of von Willebrand\u2019s disease by flow cytometry","volume":"92","author":"Giannini","year":"2007","journal-title":"Haematologica"},{"key":"10.1016\/j.thromres.2022.11.021_bb0050","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1067\/mlc.2001.117406","article-title":"Platelet function analyzer (PFA-100): a tool to quantify congenital or acquired platelet dysfunction","volume":"138","author":"Jilma","year":"2001","journal-title":"J. Lab. Clin. Med."},{"key":"10.1016\/j.thromres.2022.11.021_bb0055","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1097\/00062752-200209000-00004","article-title":"Clinical application of the PFA-100","volume":"9","author":"Favaloro","year":"2002","journal-title":"Curr. Opin. Hematol."},{"key":"10.1016\/j.thromres.2022.11.021_bb0060","doi-asserted-by":"crossref","first-page":"890","DOI":"10.1111\/j.1538-7836.2004.00780.x","article-title":"Are the bleeding time and PFA-100 useful in the initial screening of patients with mucocutaneous bleedings of hereditary nature?","volume":"2","author":"Cattaneo","year":"2004","journal-title":"J. Thromb. Haemost."},{"key":"10.1016\/j.thromres.2022.11.021_bb0065","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1016\/S0049-3848(99)00102-4","article-title":"Evaluation of platelet function with the PFA-100 system in patients with congenital defects of platelet secretion","volume":"96","author":"Cattaneo","year":"1999","journal-title":"Thromb. Res."}],"container-title":["Thrombosis Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0049384822004704?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0049384822004704?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T14:26:04Z","timestamp":1777472764000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0049384822004704"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,1]]},"references-count":13,"alternative-id":["S0049384822004704"],"URL":"https:\/\/doi.org\/10.1016\/j.thromres.2022.11.021","relation":{},"ISSN":["0049-3848"],"issn-type":[{"value":"0049-3848","type":"print"}],"subject":[],"published":{"date-parts":[[2023,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Usefulness of global tests of primary hemostasis in the initial screening of mild\/moderate bleeding disorders for orienting towards von Willebrand disease or inherited platelet functions disorders","name":"articletitle","label":"Article Title"},{"value":"Thrombosis Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.thromres.2022.11.021","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"simple-article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}