{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,25]],"date-time":"2025-09-25T00:21:13Z","timestamp":1758759673480,"version":"3.44.0"},"reference-count":32,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T00:00:00Z","timestamp":1693526400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T00:00:00Z","timestamp":1693526400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T00:00:00Z","timestamp":1693526400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T00:00:00Z","timestamp":1693526400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T00:00:00Z","timestamp":1693526400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T00:00:00Z","timestamp":1693526400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T00:00:00Z","timestamp":1693526400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","thrombosisresearch.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Thrombosis Research"],"published-print":{"date-parts":[[2023,9]]},"DOI":"10.1016\/j.thromres.2023.05.007","type":"journal-article","created":{"date-parts":[[2023,5,12]],"date-time":"2023-05-12T20:56:36Z","timestamp":1683924996000},"page":"258-262","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"special_numbering":"C","title":["The prognostic value of ORBIT risk score in predicting major bleeding in patients with acute coronary syndrome"],"prefix":"10.1016","volume":"229","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6985-6112","authenticated-orcid":false,"given":"Serhat","family":"G\u00fcnl\u00fc","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6077-0416","authenticated-orcid":false,"given":"Abdulkadir","family":"Arpa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8875-5672","authenticated-orcid":false,"given":"Fethullah","family":"Kayan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8470-1928","authenticated-orcid":false,"given":"Tuncay","family":"G\u00fczel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8338-4948","authenticated-orcid":false,"given":"Raif","family":"K\u0131l\u0131\u00e7","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0505-9784","authenticated-orcid":false,"given":"Adem","family":"Aktan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1662-3061","authenticated-orcid":false,"given":"Bernas","family":"Altinta\u015f","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8145-9574","authenticated-orcid":false,"given":"Mehmet Z\u00fclkif","family":"Karahan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.thromres.2023.05.007_bb0005","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1093\/eurheartj\/ehx393","volume":"39","author":"Ibanez","year":"2018","journal-title":"Eur. Heart J."},{"issue":"42","key":"10.1016\/j.thromres.2023.05.007_bb0010","first-page":"1289","article-title":"ESC Guidelines for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation","volume":"2021","author":"Collet","year":"2020","journal-title":"Eur. Heart J."},{"key":"10.1016\/j.thromres.2023.05.007_bb0015","doi-asserted-by":"crossref","first-page":"774","DOI":"10.1161\/CIRCULATIONAHA.106.612812","article-title":"Adverse impact of bleeding on prognosis in patients with acute coronary syndromes","volume":"114","author":"Eikelboom","year":"2006","journal-title":"Circulation"},{"key":"10.1016\/j.thromres.2023.05.007_bb0020","doi-asserted-by":"crossref","DOI":"10.1093\/eurheartj\/ehac544.1402","article-title":"Dual antiplatelet therapy duration after percutaneous coronary intervention in high bleeding risk: a meta-analysis of randomized trials","author":"Costa","year":"2022","journal-title":"Eur. Heart J."},{"issue":"14","key":"10.1016\/j.thromres.2023.05.007_bb0025","doi-asserted-by":"crossref","first-page":"1873","DOI":"10.1161\/CIRCULATIONAHA.108.828541","article-title":"Baseline risk of major bleeding in non-ST-segment-elevation myocardial infarction: the CRUSADE (Can Rapid risk stratification of Unstable angina patients Suppress ADverse outcomes with Early implementation of the ACC\/AHA Guidelines) Bleeding Score","volume":"119","author":"Subherwal","year":"2009","journal-title":"Circulation"},{"key":"10.1016\/j.thromres.2023.05.007_bb0030","doi-asserted-by":"crossref","first-page":"775","DOI":"10.1016\/j.thromres.2015.08.015","article-title":"HAS-BLED score predicts risk of in-hospital major bleeding in patients with acute non-ST segment elevation myocardial infarction","volume":"136","author":"Hsieh","year":"2015","journal-title":"Thromb. Res."},{"key":"10.1016\/j.thromres.2023.05.007_bb0035","doi-asserted-by":"crossref","first-page":"1621","DOI":"10.1007\/s00380-019-01405-1","article-title":"Utility of the HAS-BLED score for risk stratification of patients with acute coronary syndrome","volume":"34","author":"Castini","year":"2019","journal-title":"Heart Vessel."},{"key":"10.1016\/j.thromres.2023.05.007_bb0040","first-page":"3258","article-title":"The ORBIT bleeding score: a simple bedside score to assess bleeding risk in atrial fibrillation","volume":"36","author":"O\u2019Brien","year":"2015","journal-title":"Eur. Heart J."},{"key":"10.1016\/j.thromres.2023.05.007_bb0045","article-title":"Atrial fibrillation: diagnosis and management-summary of NICE guidance","volume":"373","author":"Perry","year":"2021","journal-title":"BMJ"},{"key":"10.1016\/j.thromres.2023.05.007_bb0050","doi-asserted-by":"crossref","DOI":"10.3389\/fcvm.2022.878270","article-title":"In-hospital major bleeding in patients with acute coronary syndrome medically treated with dual anti-platelet therapy: associated factors and impact on mortality","volume":"9","author":"Sun","year":"2022","journal-title":"Front. Cardiovasc. Med."},{"key":"10.1016\/j.thromres.2023.05.007_bb0055","doi-asserted-by":"crossref","first-page":"2556","DOI":"10.1016\/j.jacc.2009.09.076","article-title":"A risk score to predict bleeding in patients with acute coronary syndromes","volume":"55","author":"Mehran","year":"2010","journal-title":"J. Am. Coll. Cardiol."},{"key":"10.1016\/j.thromres.2023.05.007_bb0060","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1093\/ehjcvp\/pvac060","article-title":"Predicting performance of the HAS-BLED and ORBIT bleeding risk scores in patients with atrial fibrillation treated with Rivaroxaban: observations from the prospective EMIR Registry","volume":"9","author":"Esteve-Pastor","year":"2022","journal-title":"Eur. Heart J. Cardiovasc. Pharmacother."},{"key":"10.1016\/j.thromres.2023.05.007_bb0065","doi-asserted-by":"crossref","first-page":"175","DOI":"10.7775\/rac.es.v90.i3.20521","article-title":"Evaluaci\u00f3n del Orbit Bleeding Risk Score como predictor de sangrado mayor en pacientes con s\u00edndrome coronario agudo","volume":"90","author":"Chirino Navarta","year":"2022","journal-title":"Rev. Argent. Cardiol."},{"key":"10.1016\/j.thromres.2023.05.007_bb0070","doi-asserted-by":"crossref","first-page":"2736","DOI":"10.1161\/CIRCULATIONAHA.110.009449","article-title":"Standardized bleeding definitions for cardiovascular clinical trials: a consensus report from the Bleeding Academic Research Consortium","volume":"123","author":"Mehran","year":"2011","journal-title":"Circulation"},{"key":"10.1016\/j.thromres.2023.05.007_bb0075","doi-asserted-by":"crossref","first-page":"837","DOI":"10.2307\/2531595","article-title":"Comparing the areas under two or more correlated receiver operating characteristic curves: a nonparametric approach","volume":"44","author":"DeLong","year":"1988","journal-title":"Biometrics"},{"key":"10.1016\/j.thromres.2023.05.007_bb0080","doi-asserted-by":"crossref","first-page":"1854","DOI":"10.1093\/eurheartj\/ehr204","article-title":"Bleeding in acute coronary syndromes and percutaneous coronary interventions: position paper by the Working Group on Thrombosis of the European Society of Cardiology","volume":"32","author":"Steg","year":"2011","journal-title":"Eur. Heart J."},{"key":"10.1016\/j.thromres.2023.05.007_bb0085","doi-asserted-by":"crossref","first-page":"1815","DOI":"10.1016\/S0195-668X(03)00485-8","article-title":"Predictors of major bleeding in acute coronary syndromes: the Global Registry of Acute Coronary Events (GRACE)","volume":"24","author":"Moscucci","year":"2003","journal-title":"Eur. Heart J."},{"key":"10.1016\/j.thromres.2023.05.007_bb0090","doi-asserted-by":"crossref","DOI":"10.1161\/JAHA.119.012741","article-title":"Impact of baseline anemia in patients with acute coronary syndromes undergoing percutaneous coronary intervention: a prespecified analysis from the VALIDATE-SWEDEHEART Trial","volume":"8","author":"Wester","year":"2019","journal-title":"J. Am. Heart Assoc."},{"key":"10.1016\/j.thromres.2023.05.007_bb0095","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0262997","article-title":"Anemia or other comorbidities? using machine learning to reveal deeper insights into the drivers of acute coronary syndromes in hospital admitted patients","volume":"17","author":"Alsayegh","year":"2022","journal-title":"PLoS One"},{"key":"10.1016\/j.thromres.2023.05.007_bb0100","doi-asserted-by":"crossref","first-page":"622","DOI":"10.1038\/ki.2013.243","article-title":"Comments on \u2018KDIGO 2012 clinical practice guideline for the evaluation and management of chronic kidney disease\u2019","volume":"84","author":"Andrassy","year":"2013","journal-title":"Kidney Int."},{"key":"10.1016\/j.thromres.2023.05.007_bb0105","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1161\/01.CIR.104.3.263","article-title":"Simple bedside additive tool for prediction of in-hospital mortality after percutaneous coronary interventions","volume":"104","author":"Moscucci","year":"2001","journal-title":"Circulation"},{"issue":"6","key":"10.1016\/j.thromres.2023.05.007_bb0110","doi-asserted-by":"crossref","first-page":"578","DOI":"10.1016\/j.jacc.2019.11.056","article-title":"Ticagrelor with or without aspirin after PCI: the TWILIGHT Platelet Substudy","volume":"75","author":"Baber","year":"2020","journal-title":"J. Am. Coll. Cardiol."},{"issue":"8","key":"10.1016\/j.thromres.2023.05.007_bb0115","doi-asserted-by":"crossref","first-page":"e93","DOI":"10.1093\/cvr\/cvaa135","article-title":"Duration of antiplatelet therapy after complex PCI in the TWILIGHT-COMPLEX trial: the Goldilocks dilemma","volume":"116","author":"Santos-Gallego","year":"2020","journal-title":"Cardiovasc. Res."},{"key":"10.1016\/j.thromres.2023.05.007_bb0120","first-page":"222","article-title":"Comparing the predictive validity of three contemporary bleeding risk scores in acute coronary syndrome","volume":"1","author":"Abu-Assi","year":"2012","journal-title":"Eur. Heart J. Acute Cardiovasc. Care"},{"key":"10.1016\/j.thromres.2023.05.007_bb0125","doi-asserted-by":"crossref","first-page":"652","DOI":"10.1016\/j.thromres.2013.09.019","article-title":"CRUSADE bleeding risk score validation for ST-segment-elevation myocardial infarction undergoing primary percutaneous coronary intervention","volume":"132","author":"Ariza-Sol\u00e9","year":"2013","journal-title":"Thromb. Res."},{"key":"10.1016\/j.thromres.2023.05.007_bb0130","doi-asserted-by":"crossref","first-page":"1749","DOI":"10.1016\/j.hlc.2020.04.008","article-title":"Meta-analysis of bleeding scores performance for acute coronary syndrome","volume":"29","author":"Wang","year":"2020","journal-title":"Heart Lung Circ."},{"key":"10.1016\/j.thromres.2023.05.007_bb0135","doi-asserted-by":"crossref","first-page":"833","DOI":"10.1093\/eurheartj\/ehz593","article-title":"Temporal trends in bleeding events in acute myocardial infarction: insights from the SWEDEHEART registry","volume":"41","author":"Simonsson","year":"2020","journal-title":"Eur. Heart J."},{"key":"10.1016\/j.thromres.2023.05.007_bb0140","doi-asserted-by":"crossref","first-page":"3743","DOI":"10.1093\/eurheartj\/ehaa671","article-title":"Validation of high bleeding risk criteria and definition as proposed by the academic research consortium for high bleeding risk","volume":"41","author":"Corpataux","year":"2020","journal-title":"Eur. Heart J."},{"key":"10.1016\/j.thromres.2023.05.007_bb0145","doi-asserted-by":"crossref","DOI":"10.1155\/2022\/2586400","article-title":"Development and validation of a nomogram for predicting mortality in patients with atrial fibrillation and acute coronary syndrome who underwent percutaneous coronary intervention in a chinese multicenter cohort","volume":"2022","author":"Hua","year":"2022","journal-title":"Appl. Bionics Biomech."},{"key":"10.1016\/j.thromres.2023.05.007_bb0150","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1016\/j.jacc.2021.11.035","article-title":"Antithrombotic therapy in patients with atrial fibrillation after acute coronary syndromes or percutaneous intervention","volume":"79","author":"Harskamp","year":"2022","journal-title":"J. Am. Coll. Cardiol."},{"key":"10.1016\/j.thromres.2023.05.007_bb0155","doi-asserted-by":"crossref","first-page":"198","DOI":"10.5830\/CVJA-2019-014","article-title":"Performance of HAS-BLED and CRUSADE risk scores for the prediction of haemorrhagic events in patients with stable coronary artery disease","volume":"30","author":"Yildirim","year":"2019","journal-title":"Cardiovasc. J. Afr."},{"issue":"6","key":"10.1016\/j.thromres.2023.05.007_bb0160","doi-asserted-by":"crossref","first-page":"900","DOI":"10.1080\/09537104.2021.2007870","article-title":"Predictive performance of different bleeding risk scores in patients with atrial fibrillation and acute coronary syndrome or undergoing percutaneous coronary intervention","volume":"33","author":"Lyu","year":"2022","journal-title":"Platelets."}],"container-title":["Thrombosis Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0049384823001330?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0049384823001330?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,24]],"date-time":"2025-09-24T17:53:00Z","timestamp":1758736380000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0049384823001330"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,9]]},"references-count":32,"alternative-id":["S0049384823001330"],"URL":"https:\/\/doi.org\/10.1016\/j.thromres.2023.05.007","relation":{},"ISSN":["0049-3848"],"issn-type":[{"type":"print","value":"0049-3848"}],"subject":[],"published":{"date-parts":[[2023,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The prognostic value of ORBIT risk score in predicting major bleeding in patients with acute coronary syndrome","name":"articletitle","label":"Article Title"},{"value":"Thrombosis Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.thromres.2023.05.007","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}