{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,23]],"date-time":"2025-09-23T00:40:01Z","timestamp":1758588001248,"version":"3.44.0"},"reference-count":24,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2008,8,1]],"date-time":"2008-08-01T00:00:00Z","timestamp":1217548800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2008,8,1]],"date-time":"2008-08-01T00:00:00Z","timestamp":1217548800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Tissue and Cell"],"published-print":{"date-parts":[[2008,8]]},"DOI":"10.1016\/j.tice.2008.02.004","type":"journal-article","created":{"date-parts":[[2008,4,11]],"date-time":"2008-04-11T15:16:26Z","timestamp":1207926986000},"page":"293-298","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":5,"title":["Morphological changes and EGF expression in the granular convoluted tubule cells of submandibular glands of Trypanosoma cruzi infected rats"],"prefix":"10.1016","volume":"40","author":[{"given":"A.","family":"Moreira","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.H.","family":"Napimoga","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B.B.","family":"Benatti","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G.A.B.","family":"Silva","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D.B.","family":"Rocha-Rodrigues","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.T.","family":"Clemente-Napimoga","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gustavo A.","family":"Vieira","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.B.","family":"Alves","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.tice.2008.02.004_bib1","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1016\/0003-9969(80)90049-7","article-title":"Histological and histoquantitative study of the rat submandibular gland in Chagas\u2019 disease","volume":"25","author":"Alves","year":"1980","journal-title":"Arch. Oral Biol."},{"key":"10.1016\/j.tice.2008.02.004_bib2","doi-asserted-by":"crossref","first-page":"647","DOI":"10.1016\/0003-9969(84)90136-5","article-title":"Changes in acetylcholinesterase-positive nerves of the submandibular salivary gland during experimental infection with a protozoon, Trypanosoma cruzi, in rats","volume":"29","author":"Alves","year":"1984","journal-title":"Arch. Oral Biol."},{"key":"10.1016\/j.tice.2008.02.004_bib3","first-page":"761","article-title":"Morphology of rat submandibular gland acinar secretory granules and their alteration during the acute phase of experimental Chagas\u2019 disease","volume":"28","author":"Alves","year":"1995","journal-title":"Braz. J. Med. Biol. Res."},{"key":"10.1016\/j.tice.2008.02.004_bib4","doi-asserted-by":"crossref","first-page":"591","DOI":"10.1023\/A:1003258514766","article-title":"Occurrence and nuclear localization of cAMP response element-binding protein in the post-natal development of the rat submandibular gland","volume":"30","author":"Amano","year":"1998","journal-title":"Histochem. J."},{"key":"10.1016\/j.tice.2008.02.004_bib5","first-page":"656","article-title":"Epidermal growth factor, renin, and peptidase in cultured tumor cells of submandibular gland origin","volume":"42","author":"Barka","year":"1980","journal-title":"Lab. Invest."},{"key":"10.1016\/j.tice.2008.02.004_bib6","first-page":"404","article-title":"Gastric juice immunoreactive epidermal growth factor levels in patients with peptic ulcer disease","volume":"85","author":"Calabro","year":"1990","journal-title":"Am. J. Gastroenterol."},{"key":"10.1016\/j.tice.2008.02.004_bib7","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1016\/S0074-7696(08)60101-1","article-title":"Action of testosterone on the differentiation and secretory activity of a target organ: the submaxillary gland of the mouse","volume":"50","author":"Chretien","year":"1977","journal-title":"Int. Rev. Cytol."},{"key":"10.1016\/j.tice.2008.02.004_bib8","series-title":"The testis","article-title":"Spermatogenesis.","author":"Courout","year":"1970"},{"key":"10.1016\/j.tice.2008.02.004_bib9","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1002\/jemt.1070270102","article-title":"The granular convoluted tubule (GCT) cell of rodent submandibular glands","volume":"27","author":"Gresik","year":"1994","journal-title":"Microsc. Res. Tech."},{"key":"10.1016\/j.tice.2008.02.004_bib10","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1016\/S0140-6736(05)78271-4","article-title":"Epidermal growth factor in saliva and serum of infants with necrotising enterocolitis","volume":"351","author":"Helmrath","year":"1998","journal-title":"Lancet"},{"key":"10.1016\/j.tice.2008.02.004_bib11","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1677\/joe.0.1400357","article-title":"Developmental changes in and hormonal modulation of epidermal growth factor concentration in the rat submandibular gland","volume":"140","author":"Hiramatsu","year":"1994","journal-title":"J. Endocrinol."},{"key":"10.1016\/j.tice.2008.02.004_bib12","first-page":"138","article-title":"Increased rate of salivary epidermal growth factor secretion in patients with juvenile periodontitis","volume":"101","author":"Hormia","year":"1993","journal-title":"Scand. J. Dent. Res."},{"key":"10.1016\/j.tice.2008.02.004_bib13","first-page":"A1485","article-title":"Salivary epidermal growth factor deficiency in rheumatoid disease: influence of sicca syndrome","volume":"30","author":"Kelly","year":"1989","journal-title":"Gut"},{"issue":"4","key":"10.1016\/j.tice.2008.02.004_bib14","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1007\/BF01255597","article-title":"Adrenergic innervation and noradrenaline content of the rat submandibular gland during the experimental Trypanosoma cruzi infection","volume":"59","author":"Machado","year":"1984","journal-title":"J Neural Transm"},{"key":"10.1016\/j.tice.2008.02.004_bib15","first-page":"160","article-title":"Salivary immunoreactive human epidermal growth factor (IR-hEGF) in patients with peptic ulcer disease","volume":"34","author":"Ohmura","year":"1987","journal-title":"Hepato-Gastroenterology"},{"key":"10.1016\/j.tice.2008.02.004_bib16","doi-asserted-by":"crossref","first-page":"1234","DOI":"10.1136\/gut.25.11.1234","article-title":"Adrenergic effects on exocrine secretion of rat submandibular epidermal growth factor","volume":"25","author":"Olsen","year":"1984","journal-title":"Gut"},{"key":"10.1016\/j.tice.2008.02.004_bib17","first-page":"A758","article-title":"Lower levels of epidermal growth factor in saliva from patients with Crohn's disease and ulcerative colitis","volume":"106","author":"Rao","year":"1994","journal-title":"Gastroenterology"},{"key":"10.1016\/j.tice.2008.02.004_bib18","doi-asserted-by":"crossref","first-page":"2175","DOI":"10.1023\/A:1018855525989","article-title":"Salivary epidermal growth factor plays a role in protection of ideal mucosal integrity","volume":"42","author":"Rao","year":"1997","journal-title":"Dig. Dis. Sci."},{"key":"10.1016\/j.tice.2008.02.004_bib19","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1159\/000097197","article-title":"The submandibular gland: a key organ in the neuro-immuno-regulatory network?","volume":"2","author":"Sabbadini","year":"1995","journal-title":"Neuroimmunomodulation"},{"key":"10.1016\/j.tice.2008.02.004_bib20","doi-asserted-by":"crossref","first-page":"1421","DOI":"10.1016\/S0006-291X(88)80444-3","article-title":"Role of salivary epidermal growth factor in the maintenance of physicochemical characteristics of oral and gastric mucosal mucus coat","volume":"152","author":"Sarosiek","year":"1988","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.tice.2008.02.004_bib21","first-page":"191","article-title":"Sobre uma cepa de Trypanosoma cruzi altamente virulenta para o camundongo branco","volume":"20","author":"Silva","year":"1953","journal-title":"Folia Clin. Biol."},{"key":"10.1016\/j.tice.2008.02.004_bib22","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1051\/parasite\/2000072109","article-title":"Histological and histoquantitative study of the rat parotid gland after Trypanosoma cruzi infection","volume":"7","author":"Silva","year":"2000","journal-title":"Parasite"},{"key":"10.1016\/j.tice.2008.02.004_bib23","doi-asserted-by":"crossref","first-page":"262","DOI":"10.1016\/S1471-4922(02)02283-3","article-title":"Chemokines, inflammation and Trypanosoma cruzi infection","volume":"18","author":"Teixeira","year":"2002","journal-title":"Trends Parasitol."},{"key":"10.1016\/j.tice.2008.02.004_bib24","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/S0167-0115(02)00058-7","article-title":"Altered secretion and processing of epidermal growth factor in adrenergic-induced growth of the rat submandibular gland","volume":"106","author":"Thulesen","year":"2002","journal-title":"Regul. Pept."}],"container-title":["Tissue and Cell"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0040816608000141?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0040816608000141?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,22]],"date-time":"2025-09-22T20:09:27Z","timestamp":1758571767000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0040816608000141"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,8]]},"references-count":24,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2008,8]]}},"alternative-id":["S0040816608000141"],"URL":"https:\/\/doi.org\/10.1016\/j.tice.2008.02.004","relation":{},"ISSN":["0040-8166"],"issn-type":[{"type":"print","value":"0040-8166"}],"subject":[],"published":{"date-parts":[[2008,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Morphological changes and EGF expression in the granular convoluted tubule cells of submandibular glands of Trypanosoma cruzi infected rats","name":"articletitle","label":"Article Title"},{"value":"Tissue and Cell","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.tice.2008.02.004","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2008 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}