{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,12]],"date-time":"2026-05-12T11:38:13Z","timestamp":1778585893311,"version":"3.51.4"},"reference-count":74,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2021,12,1]],"date-time":"2021-12-01T00:00:00Z","timestamp":1638316800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,12,1]],"date-time":"2021-12-01T00:00:00Z","timestamp":1638316800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,12,1]],"date-time":"2021-12-01T00:00:00Z","timestamp":1638316800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2021,12,1]],"date-time":"2021-12-01T00:00:00Z","timestamp":1638316800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2021,12,1]],"date-time":"2021-12-01T00:00:00Z","timestamp":1638316800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2021,12,1]],"date-time":"2021-12-01T00:00:00Z","timestamp":1638316800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2021,12,1]],"date-time":"2021-12-01T00:00:00Z","timestamp":1638316800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100003593","name":"Conselho Nacional de Desenvolvimento Cient\u00edfico e Tecnol\u00f3gico","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003593","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004901","name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa do Estado de Minas Gerais","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004901","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002322","name":"CAPES","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002322","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Tissue and Cell"],"published-print":{"date-parts":[[2021,12]]},"DOI":"10.1016\/j.tice.2021.101658","type":"journal-article","created":{"date-parts":[[2021,9,27]],"date-time":"2021-09-27T02:19:33Z","timestamp":1632709173000},"page":"101658","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":5,"special_numbering":"C","title":["BEWO trophoblast cells and Toxoplasma gondii infection modulate cell death mechanisms in THP-1 monocyte cells by interference in the expression of death receptor and intracellular proteins"],"prefix":"10.1016","volume":"73","author":[{"given":"Andressa","family":"da Silva Castro","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mariana Bodini","family":"Angeloni","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bellisa","family":"de Freitas Barbosa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Renata Lima","family":"de Miranda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1978-1658","authenticated-orcid":false,"given":"Samuel Cota","family":"Teixeira","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P\u00e2mela Mendon\u00e7a","family":"Guirelli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fernanda Chaves","family":"de Oliveira","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rafaela","family":"Jos\u00e9 da Silva","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Priscila Silva","family":"Franco","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mayara","family":"Ribeiro","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Iliana Claudia Balga","family":"Milian","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ang\u00e9lica","family":"de Oliveira Gomes","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2160-8790","authenticated-orcid":false,"given":"Francesca","family":"Ietta","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S\u00edlvio Favoreto","family":"J\u00fanior","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2339-2743","authenticated-orcid":false,"given":"Tiago Wilson Patriarca","family":"Mineo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9010-7228","authenticated-orcid":false,"given":"Jos\u00e9 Roberto","family":"Mineo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Celene Maria","family":"de Oliveira Sim\u00f5es Alves","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7447-2583","authenticated-orcid":false,"given":"Eloisa Am\u00e1lia Vieira","family":"Ferro","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.tice.2021.101658_bib0005","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1093\/molehr\/gah006","article-title":"First trimester trophoblast cells secrete Fas ligand which induces immune cells apoptosis","volume":"10","author":"Abrahams","year":"2004","journal-title":"Mol. Hum. Reprod."},{"key":"10.1016\/j.tice.2021.101658_bib0010","doi-asserted-by":"crossref","first-page":"785","DOI":"10.1016\/j.placenta.2009.07.002","article-title":"Apoptosis and S phase of the cell cycle in BeWo trophoblastic and Hela cells are differentially modulated by Toxoplasma gondii strain types","volume":"30","author":"Angeloni","year":"2009","journal-title":"Placenta"},{"key":"10.1016\/j.tice.2021.101658_bib0015","doi-asserted-by":"crossref","first-page":"973","DOI":"10.1016\/j.placenta.2013.09.005","article-title":"Differential apoptosis in BeWo cells after infection with highly (R.H.) or moderately (ME49) virulent strains of Toxoplasma gondii is related to the cytokine profile secreted, the death receptor Fas expression and phosphorylated ERK1\/2 expression","volume":"34","author":"Angeloni","year":"2013","journal-title":"Placenta"},{"key":"10.1016\/j.tice.2021.101658_bib0020","doi-asserted-by":"crossref","first-page":"4829","DOI":"10.3748\/wjg.v21.i16.4829","article-title":"Toxoplasma gondii causes death and plastic alteration in the jejuna myenteric plexus","volume":"21","author":"Araujo","year":"2015","journal-title":"World J. Gastroenterol."},{"key":"10.1016\/j.tice.2021.101658_bib0025","doi-asserted-by":"crossref","first-page":"1305","DOI":"10.1126\/science.281.5381.1305","article-title":"Death receptors: signaling and modulation","volume":"281","author":"Aschkenazi","year":"1998","journal-title":"Science"},{"key":"10.1016\/j.tice.2021.101658_bib0030","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1016\/j.resp.2011.04.016","article-title":"Dual role of TGF-\u03b21 on Fas-induced apoptosis in lung epithelial cells","volume":"177","author":"Bai","year":"2011","journal-title":"Respir. Physiol. Neurobiol."},{"key":"10.1016\/j.tice.2021.101658_bib0035","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0197702","article-title":"Macrophage Migration Inhibitory Factor protects cancer cells from immunogenic cell death and impairs anti-tumor immune responses","volume":"13","author":"Balogh","year":"2018","journal-title":"PLoS One"},{"key":"10.1016\/j.tice.2021.101658_bib0040","doi-asserted-by":"crossref","first-page":"624","DOI":"10.1016\/j.placenta.2006.10.011","article-title":"Susceptibility to vertical transmission of Toxoplasma gondii is temporally dependent on the preconceptional infection in Camomys callosus","volume":"28","author":"Barbosa","year":"2007","journal-title":"Placenta"},{"key":"10.1016\/j.tice.2021.101658_bib0045","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1095\/biolreprod.114.124115","article-title":"IL-10, TGF beta1, and IFN gamma modulate intracellular signaling pathways and cytokine production to control Toxoplasma gondii infection in BeWo trophoblast cells","volume":"92","author":"Barbosa","year":"2015","journal-title":"Biol. Reprod."},{"key":"10.1016\/j.tice.2021.101658_bib0050","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1016\/0003-2697(76)90527-3","article-title":"A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding","volume":"72","author":"Bradford","year":"1976","journal-title":"Anal. Biochem."},{"key":"10.1016\/j.tice.2021.101658_bib0055","doi-asserted-by":"crossref","first-page":"25215","DOI":"10.1074\/jbc.M512627200","article-title":"p38 MAP kinase mediates apoptosis through phosphorylation of BimEL at Ser-65","volume":"281","author":"Cai","year":"2006","journal-title":"G Biol. Chem."},{"key":"10.1016\/j.tice.2021.101658_bib0060","doi-asserted-by":"crossref","first-page":"1204","DOI":"10.1016\/j.cellsig.2014.02.013","article-title":"Toxoplasma gondii inhibits apoptosis via a novel STAT3-miR-17-92-Bim pathway in macrophages","volume":"26","author":"Cai","year":"2014","journal-title":"Cell. Signal."},{"key":"10.1016\/j.tice.2021.101658_bib0065","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1016\/j.placenta.2012.12.006","article-title":"Trophoblast cells are able to regulate monocyte activity to control Toxoplasma gondii infection","volume":"34","author":"Castro","year":"2013","journal-title":"Placenta"},{"key":"10.1016\/j.tice.2021.101658_bib0070","doi-asserted-by":"crossref","first-page":"624","DOI":"10.1111\/j.1600-0897.2010.00832.x","article-title":"Tolerance to the foetal allograft?","volume":"63","author":"Chaouat","year":"2010","journal-title":"Am. J. Reprod. Immunol."},{"key":"10.1016\/j.tice.2021.101658_bib0075","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1016\/S0022-1759(02)00070-4","article-title":"Regulation and measurement of oxidative stress in apoptosis","volume":"265","author":"Curtin","year":"2002","journal-title":"J. Immunol. Methods"},{"key":"10.1016\/j.tice.2021.101658_bib0080","doi-asserted-by":"crossref","first-page":"551","DOI":"10.1007\/s10495-011-0586-0","article-title":"Toxoplasma gondii Dense Granule Antigen 1 stimulates apoptosis of monocytes through autocrine TGF-\u03b2 signaling","volume":"16","author":"D\u2019Angelillo","year":"2011","journal-title":"Apoptosis"},{"key":"10.1016\/j.tice.2021.101658_bib0085","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1016\/S0928-8244(03)00279-7","article-title":"From cells to signaling cascades: manipulation of innate immunity by Toxoplasma gondii, FEMS","volume":"39","author":"Denkers","year":"2003","journal-title":"Immunol. Med. Microbiol."},{"key":"10.1016\/j.tice.2021.101658_bib0090","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1128\/CMR.11.4.569","article-title":"Regulation and function of T-cell-mediated immunity during Toxoplasma gondii infection","volume":"11","author":"Denkers","year":"1988","journal-title":"Clin. Microbiol."},{"key":"10.1016\/j.tice.2021.101658_bib0095","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1128\/CMR.11.2.267","article-title":"Structures of Toxoplasma gondii tachyzoites, bradyzoites, and sporozoites and biology and development of tissue cysts","volume":"11","author":"Dubey","year":"1998","journal-title":"Clin. Microbiol. Rev."},{"key":"10.1016\/j.tice.2021.101658_bib0100","doi-asserted-by":"crossref","first-page":"330","DOI":"10.18632\/aging.100459","article-title":"Role of apoptosis in disease","volume":"4","author":"Favaloro","year":"2012","journal-title":"Aging (Albany NY)"},{"key":"10.1016\/j.tice.2021.101658_bib0105","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1111\/j.1600-0897.2006.00446.x","article-title":"Trophoblast-Macrophage Interactions: a regulatory network for the protection of pregnancy","volume":"57","author":"Fest","year":"2007","journal-title":"Am. J. Reprod. Immunol."},{"key":"10.1016\/j.tice.2021.101658_bib0110","first-page":"30021","article-title":"Toxoplasmosis in blood donors: a systematic review and meta-analysis","volume":"15","author":"Foroutan-Rad","year":"2016","journal-title":"Transfus. Med. Rev."},{"key":"10.1016\/j.tice.2021.101658_bib0115","doi-asserted-by":"crossref","first-page":"838","DOI":"10.1016\/j.placenta.2011.08.012","article-title":"Azithromycin and spiramycin induce anti-inflammatory response in human trophoblastic (BeWo) cells infected by Toxoplasma gondii but are able to control infection","volume":"32","author":"Franco","year":"2011","journal-title":"Placenta"},{"key":"10.1016\/j.tice.2021.101658_bib0120","doi-asserted-by":"crossref","first-page":"3495","DOI":"10.1242\/jcs.114.19.3495","article-title":"Inhibition of host cell apoptosis by Toxoplasma gondii is accompanied by reduced activation of the caspase cascade and alterations of poly (ADP-ribose) polymerase expression","volume":"114","author":"Goebel","year":"2001","journal-title":"J. Cell. Sci."},{"key":"10.1016\/j.tice.2021.101658_bib0125","first-page":"2793","article-title":"Effect of macrophage migration inhibitory factor (MIF) in human placental explants infected with Toxoplasma gondii depends on gestational age","volume":"178","author":"Gomes","year":"2011","journal-title":"Am. J. Pathol."},{"key":"10.1016\/j.tice.2021.101658_bib0130","doi-asserted-by":"crossref","first-page":"1106","DOI":"10.1016\/j.placenta.2015.08.009","article-title":"Trophoblast-macrophage crosstalk on human extravillous under Toxoplasma gondii infection","volume":"36","author":"Guirelli","year":"2015","journal-title":"Placenta"},{"key":"10.1016\/j.tice.2021.101658_bib0135","doi-asserted-by":"crossref","first-page":"1081","DOI":"10.1242\/jcs.090514","article-title":"BH3-only proteins in apoptosis at a glance","volume":"125","author":"Happo","year":"2012","journal-title":"J. Cell. Sci."},{"key":"10.1016\/j.tice.2021.101658_bib0140","doi-asserted-by":"crossref","first-page":"1166","DOI":"10.1016\/S0020-7519(01)00271-5","article-title":"Inhibition of apoptosis by intracellular protozoan parasites","volume":"31","author":"Heussler","year":"2001","journal-title":"Int. J. Parasitol."},{"key":"10.1016\/j.tice.2021.101658_bib0145","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1586\/14787210.2016.1146131","article-title":"Role of vertical transmission of Toxoplasma gondii in prevalence of infection","volume":"14","author":"Hide","year":"2016","journal-title":"Expert Rev. Anti. Ther."},{"key":"10.1016\/j.tice.2021.101658_bib0150","doi-asserted-by":"crossref","first-page":"2905","DOI":"10.1128\/IAI.01546-07","article-title":"Fas\/CD95-mediated apoptosis of type II cells is blocked by Toxoplasma gondii primarily via interference with the mitochondrial amplification loop","volume":"76","author":"Hippe","year":"2008","journal-title":"Infect. Immun."},{"key":"10.1016\/j.tice.2021.101658_bib0155","doi-asserted-by":"crossref","first-page":"3511","DOI":"10.1242\/jcs.050963","article-title":"Toxoplasma gondii infection confers resistance against BimS-induced apoptosis by preventing the activation and mitochondrial targeting of pro-apoptotic Bax","volume":"122","author":"Hippe","year":"2009","journal-title":"J. Cell. Sci."},{"key":"10.1016\/j.tice.2021.101658_bib0160","doi-asserted-by":"crossref","first-page":"766","DOI":"10.1038\/nrmicro2858","article-title":"Modulation of innate immunity by Toxoplasma gondii virulence effectors","volume":"10","author":"Hunter","year":"2012","journal-title":"Nat. Rev. Microbiol."},{"key":"10.1016\/j.tice.2021.101658_bib0165","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/j.ajog.2005.07.039","article-title":"Apoptosis and its role in the trophoblast","volume":"195","author":"Huppertz","year":"2006","journal-title":"Am. J. Obstet. Gynecol."},{"key":"10.1016\/j.tice.2021.101658_bib0170","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/1756-3305-3-104","article-title":"Apoptotic markers in protozoan parasites","volume":"3","author":"Jimenez-Ruiz","year":"2010","journal-title":"Parasites Vector"},{"key":"10.1016\/j.tice.2021.101658_bib0175","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1530\/rep.1.01076","article-title":"TGF-b superfamily expression and actions in the endometrium and placenta","volume":"132","author":"Jones","year":"2006","journal-title":"Reproduction"},{"key":"10.1016\/j.tice.2021.101658_bib0180","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1099\/jmm.0.45693-0","article-title":"Actinobacillus actinomycetemcomitans induces apoptosis in human monocytic THP-1 cells","volume":"54","author":"Kato","year":"2005","journal-title":"J. Med. Microbiol."},{"key":"10.1016\/j.tice.2021.101658_bib0185","first-page":"191","article-title":"Toll-Like Receptors and Pregnancy: trophoblast as modulators of the immune response","volume":"35","author":"Koga","year":"2009","journal-title":"J. Obstet. Gynecol. Res."},{"key":"10.1016\/j.tice.2021.101658_bib0190","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.actatropica.2014.12.001","article-title":"Polarization of macrophages induced by Toxoplasma gondii and its impact on abnormal pregnancy in rats","volume":"143","author":"Kong","year":"2015","journal-title":"Acta Trop."},{"key":"10.1016\/j.tice.2021.101658_bib0195","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1016\/S0014-4827(03)00391-4","article-title":"Oxidative stress-induced apoptosis is mediated by ERK1\/2 phosphorylation","volume":"291","author":"Lee","year":"2003","journal-title":"Exp. Cell Res."},{"key":"10.1016\/j.tice.2021.101658_bib0200","first-page":"219","article-title":"Apoptosis and its modulation during infection with Toxoplasma gondii: molecular mechanisms and role in pathogenesis","volume":"289","author":"L\u00fcder","year":"2005","journal-title":"Curr. Top. Microbiol. Immunol."},{"key":"10.1016\/j.tice.2021.101658_bib0205","first-page":"59","article-title":"Toxoplasmosis in immunocompromised patients","volume":"64","author":"Machala","year":"2015","journal-title":"Epidemiol. Mikrobiol. Imunol."},{"key":"10.1016\/j.tice.2021.101658_bib0210","doi-asserted-by":"crossref","DOI":"10.1155\/2019\/6152489","article-title":"Toxoplasma gondii modulates the host cell responses: an overview of apoptosis pathway","volume":"2019","author":"Mammari","year":"2019","journal-title":"Biomed. Res. Int."},{"key":"10.1016\/j.tice.2021.101658_bib0215","doi-asserted-by":"crossref","DOI":"10.4414\/smw.2015.14056","article-title":"Promoting apoptosis of neutrophils and phagocytosis by macrophages: novel strategies in the resolution of inflammation","volume":"145","author":"Martin","year":"2015","journal-title":"Swiss. Med. Wkly."},{"key":"10.1016\/j.tice.2021.101658_bib0220","doi-asserted-by":"crossref","first-page":"820","DOI":"10.1002\/fsn3.1342","article-title":"Gastrodin improves preeclampsia-induced cell apoptosis by regulation of TLR4\/NF-kB in rats","volume":"8","author":"Mei","year":"2020","journal-title":"Food Sci. Nutr."},{"key":"10.1016\/j.tice.2021.101658_bib0225","doi-asserted-by":"crossref","first-page":"4359","DOI":"10.1242\/jcs.00683","article-title":"Activation of NF-\u03baB by Toxoplasma gondii correlates with increased expression of antiapoptotic genes and localization of phosphorylated I\u03baB to the parasitophorous vacuole membrane","volume":"116","author":"Molestina","year":"2003","journal-title":"J. Cell. Sci."},{"key":"10.1016\/j.tice.2021.101658_bib0230","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1177\/1933719109349962","article-title":"The immunomodulatory roles of macrophages at the maternal-fetal interface","volume":"17","author":"Nagamatsu","year":"2010","journal-title":"Reprod. Sci."},{"key":"10.1016\/j.tice.2021.101658_bib0235","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1016\/S0065-2776(08)60672-0","article-title":"Fas and Fas ligand: a death factor and its receptor","volume":"57","author":"Nagata","year":"1994","journal-title":"Adv. Immunol."},{"key":"10.1016\/j.tice.2021.101658_bib0240","doi-asserted-by":"crossref","first-page":"3448","DOI":"10.1016\/j.bbamcr.2013.06.001","article-title":"Crosstalk between apoptosis, necrosis and autophagy","volume":"1833","author":"Nikoletopoulon","year":"2013","journal-title":"Biochim. Biophys. Acta"},{"issue":"3","key":"10.1016\/j.tice.2021.101658_bib0245","doi-asserted-by":"crossref","first-page":"641","DOI":"10.3390\/ijms20030641","article-title":"Placental CX3CL1 is deregulated by Angiotensin II and contributes to a pro-inflammatory trophoblast-monocyte interaction","volume":"20","author":"Nonn","year":"2019","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.tice.2021.101658_bib0250","doi-asserted-by":"crossref","first-page":"4345","DOI":"10.1242\/jcs.00756","article-title":"Inhibition of caspase activation and a requirement for NF-kappaB function in the Toxoplasma gondii-mediated blockade of host apoptosis","volume":"116","author":"Payne","year":"2003","journal-title":"J. Cell. Sci."},{"key":"10.1016\/j.tice.2021.101658_bib0255","doi-asserted-by":"crossref","first-page":"620","DOI":"10.1645\/GE-2712.1","article-title":"A review: competence, compromise, and concomitance-reaction of the host cell to Toxoplasma gondii infection and development","volume":"97","author":"Peng","year":"2011","journal-title":"J. Parasitol."},{"key":"10.1016\/j.tice.2021.101658_bib0260","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1093\/molehr\/gas027","article-title":"Aberrant expression of corticotropin-releasing hormone in pre-eclampsia induces expression of FasL in maternal macrophages and extravillous trophoblast apoptosis","volume":"18","author":"Petsas","year":"2012","journal-title":"Mol. Hum. Reprod."},{"key":"10.1016\/j.tice.2021.101658_bib0265","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pntd.0005222","article-title":"Congenital toxoplasmosis in France and the United States: one parasite, two diverging approaches","volume":"11","author":"Peyron","year":"2017","journal-title":"PLoS Negl. Trop. Dis."},{"key":"10.1016\/j.tice.2021.101658_bib0270","doi-asserted-by":"crossref","first-page":"24","DOI":"10.3390\/pathogens8010024","article-title":"Maternal and congenital toxoplasmosis: diagnosis and treatment recommendations of a French multidisciplinary working group","volume":"8","author":"Peyron","year":"2019","journal-title":"Pathogens"},{"key":"10.1016\/j.tice.2021.101658_bib0275","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1016\/S0090-8258(03)00396-2","article-title":"Resistance to Fas-mediated cell death in BeWo and NJG choriocarcinoma cell lines: implications in immune privilege","volume":"91","author":"Rajashekhar","year":"2003","journal-title":"Gynecol. Oncol."},{"key":"10.1016\/j.tice.2021.101658_bib0280","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1016\/j.exppara.2017.08.004","article-title":"Azithromycin treatment is able to control the infection by two genotypes of Toxoplasma gondii in human trophoblast BeWo cells","volume":"181","author":"Ribeiro","year":"2017","journal-title":"Exp. Parasitol."},{"key":"10.1016\/j.tice.2021.101658_bib0285","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1111\/j.1462-5822.2011.01737.x","article-title":"Modulation of mammalian apoptotic pathways by intracellular protozoan parasites","volume":"14","author":"Rodrigues","year":"2012","journal-title":"Cell. Microbiol."},{"key":"10.1016\/j.tice.2021.101658_bib0290","doi-asserted-by":"crossref","first-page":"2598","DOI":"10.1093\/humrep\/des208","article-title":"Trophoblast cells induce a tolerogenic profile in dendritic cells","volume":"27","author":"Salamone","year":"2012","journal-title":"Hum. Reprod."},{"key":"10.1016\/j.tice.2021.101658_bib0295","doi-asserted-by":"crossref","first-page":"592","DOI":"10.1016\/j.tmaid.2014.05.007","article-title":"Toxoplasmosis as a travel risk","volume":"12","author":"Sepulveda-Arias","year":"2014","journal-title":"Travel Med. Infect. Dis."},{"key":"10.1016\/j.tice.2021.101658_bib0300","first-page":"3501","article-title":"The role of apoptosis in the regulation of trophoblast survival and differentiation during pregnancy","volume":"118","author":"Shawan","year":"2005","journal-title":"Endocr. Rev."},{"key":"10.1016\/j.tice.2021.101658_bib0305","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/j.cbi.2009.07.016","article-title":"Apigenin-induced apoptosis is mediated by reactive oxygen species and activation of ERK1\/2 in rheumatoid fibroblast-like synoviocytes","volume":"182","author":"Shin","year":"2009","journal-title":"Chem. Biol. Interact."},{"key":"10.1016\/j.tice.2021.101658_bib0310","doi-asserted-by":"crossref","first-page":"4279","DOI":"10.4049\/jimmunol.174.7.4279","article-title":"NADPH oxidase-derived reactive oxygen species-mediated activation of ERK1\/2 is required for apoptosis of human neutrophils induced by Entamoeba histolytica","volume":"174","author":"Sim","year":"2005","journal-title":"J. Immunol."},{"key":"10.1016\/j.tice.2021.101658_bib0315","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3347\/kjp.2012.50.1.1","article-title":"Anti-apoptotic effects of SERPIN B3 and B4 via STAT6 activation in macrophages after infection with Toxoplasma gondii","volume":"50","author":"Song","year":"2012","journal-title":"Korean J. Parasitol."},{"key":"10.1016\/j.tice.2021.101658_bib0320","doi-asserted-by":"crossref","first-page":"3667","DOI":"10.1038\/emboj.2011.307","article-title":"Deciphering the rules of programmed cell death to improve therapy of cancer and other diseases","volume":"30","author":"Strasser","year":"2011","journal-title":"EMBO J."},{"key":"10.1016\/j.tice.2021.101658_bib0325","doi-asserted-by":"crossref","first-page":"877","DOI":"10.1210\/er.2005-0003","article-title":"The role of apoptosis in the regulation of trophoblast survival and differentiation during pregnancy","volume":"26","author":"Straszewski-Chavez","year":"2005","journal-title":"Endocr. Rev."},{"key":"10.1016\/j.tice.2021.101658_bib0330","doi-asserted-by":"crossref","first-page":"3090","DOI":"10.1128\/IAI.01722-14","article-title":"Complex immune cell interplay in the gamma interferon response during Toxoplasma gondii infection","volume":"82","author":"Sturge","year":"2014","journal-title":"Infect. Immun."},{"key":"10.1016\/j.tice.2021.101658_bib0335","doi-asserted-by":"crossref","first-page":"1534","DOI":"10.4049\/jimmunol.1401536","article-title":"The human fetal placenta promotes tolerance against the semiallogeneic fetus by inducing regulatory T cells and homeostatic M2 macrophages","volume":"194","author":"Svensson-Arvelund","year":"2015","journal-title":"J. Immunol."},{"key":"10.1016\/j.tice.2021.101658_bib0340","doi-asserted-by":"crossref","first-page":"1312","DOI":"10.1126\/science.281.5381.1312","article-title":"Caspases: enemies within","volume":"281","author":"Thornberry","year":"1998","journal-title":"Science"},{"key":"10.1016\/j.tice.2021.101658_bib0345","doi-asserted-by":"crossref","DOI":"10.1155\/2018\/3651743","article-title":"Poly-L-Arginine induces apoptosis of NCI-H292 cells via ERK1\/2 signaling pathway","volume":"2018","author":"Wang","year":"2018","journal-title":"J. Immunol. Res."},{"key":"10.1016\/j.tice.2021.101658_bib0350","doi-asserted-by":"crossref","first-page":"188","DOI":"10.1016\/j.placenta.2011.12.007","article-title":"Pro-inflammatory cytokine-stimulated first trimester decidual cells enhance macrophage-induced apoptosis of extravillous trophoblasts","volume":"33","author":"Wu","year":"2012","journal-title":"Placenta"},{"key":"10.1016\/j.tice.2021.101658_bib0355","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1166\/jnn.2020.16885","article-title":"Toxoplasma gondii rhoptry protein 16 (ROP16) modifies apoptosis in human 293T Cells","volume":"20","author":"Wu","year":"2020","journal-title":"J. Nanosci. Nanotechnol."},{"key":"10.1016\/j.tice.2021.101658_bib0360","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1016\/j.ijid.2014.10.027","article-title":"Interferon gamma is involved in apoptosis of trophoblast cells at the maternal-fetal interface following Toxoplasma gondii infection","volume":"30","author":"Zhang","year":"2015","journal-title":"Int. J. Infect. Dis."},{"key":"10.1016\/j.tice.2021.101658_bib0365","doi-asserted-by":"crossref","first-page":"16","DOI":"10.3389\/fnmol.2020.00016","article-title":"Lysophosphatidic Acid induces apoptosis of PC12 cells through LPA1 receptor\/LPA2 receptor \/MAPK signaling pathway","volume":"13","author":"Zhang","year":"2020","journal-title":"Front. Mol. Neurosci."},{"key":"10.1016\/j.tice.2021.101658_bib0370","first-page":"204","article-title":"Human monocytes undergo functional re-programming during differentiation to dendritic cell by human extravillous trophoblasts","volume":"6","author":"Zhao","year":"2016","journal-title":"Sci. Rep."}],"container-title":["Tissue and Cell"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0040816621001749?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0040816621001749?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,22]],"date-time":"2025-09-22T20:25:10Z","timestamp":1758572710000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0040816621001749"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,12]]},"references-count":74,"alternative-id":["S0040816621001749"],"URL":"https:\/\/doi.org\/10.1016\/j.tice.2021.101658","relation":{},"ISSN":["0040-8166"],"issn-type":[{"value":"0040-8166","type":"print"}],"subject":[],"published":{"date-parts":[[2021,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"BEWO trophoblast cells and Toxoplasma gondii infection modulate cell death mechanisms in THP-1 monocyte cells by interference in the expression of death receptor and intracellular proteins","name":"articletitle","label":"Article Title"},{"value":"Tissue and Cell","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.tice.2021.101658","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"101658"}}