{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,22]],"date-time":"2025-09-22T20:40:15Z","timestamp":1758573615473,"version":"3.44.0"},"reference-count":31,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2023,4,1]],"date-time":"2023-04-01T00:00:00Z","timestamp":1680307200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,4,1]],"date-time":"2023-04-01T00:00:00Z","timestamp":1680307200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,4,1]],"date-time":"2023-04-01T00:00:00Z","timestamp":1680307200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2023,4,1]],"date-time":"2023-04-01T00:00:00Z","timestamp":1680307200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2023,4,1]],"date-time":"2023-04-01T00:00:00Z","timestamp":1680307200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2023,4,1]],"date-time":"2023-04-01T00:00:00Z","timestamp":1680307200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2023,4,1]],"date-time":"2023-04-01T00:00:00Z","timestamp":1680307200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Tissue and Cell"],"published-print":{"date-parts":[[2023,4]]},"DOI":"10.1016\/j.tice.2023.102016","type":"journal-article","created":{"date-parts":[[2023,1,9]],"date-time":"2023-01-09T11:23:33Z","timestamp":1673263413000},"page":"102016","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":6,"special_numbering":"C","title":["Rosemary (Rosmarinus officinalis L.) essential oil alleviates testis failure induced by Etoposide in male rats"],"prefix":"10.1016","volume":"81","author":[{"given":"Mohammadzadeh","family":"Saied","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kiani","family":"Ali","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amiri","family":"Mosayeb","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"1","key":"10.1016\/j.tice.2023.102016_bib1","first-page":"59","article-title":"Qualitative and quantitative characterization of biologically active compounds of Rosemary (Rosmarinus officinalis) Leaf Extract","volume":"2","author":"Akela","year":"2018","journal-title":"J. Adv. Trends Basic Appl. Sci."},{"issue":"7","key":"10.1016\/j.tice.2023.102016_bib2","first-page":"222","article-title":"Effects of rosemary on lipid profile in diabetic rats","volume":"6","author":"Aljamal","year":"2012","journal-title":"Afr. J. Plant Sci."},{"key":"10.1016\/j.tice.2023.102016_bib3","doi-asserted-by":"crossref","first-page":"1","DOI":"10.9734\/ajrimps\/2019\/v7i430126","article-title":"Biochemical and molecular studies on the role of rosemary (Rosmarinus officinalis) extract in reducing liver and kidney toxicity due to etoposide in male rats","author":"Almakhatreh","year":"2019","journal-title":"Asian J. Res. Med. Pharm. Sci."},{"issue":"1","key":"10.1016\/j.tice.2023.102016_bib4","first-page":"1","article-title":"Beneficial role of Panax ginseng root aqueous extract against Cisplatin induced blood toxicity in rats. Am","volume":"3","author":"Basuony","year":"2015","journal-title":"J. Biol. Chem."},{"issue":"2","key":"10.1016\/j.tice.2023.102016_bib5","first-page":"1","article-title":"Protective role of rosemary against anticancer drug Etoposide-induced testicular toxicity and oxidative stress in rats","volume":"1","author":"Bayomy","year":"2017","journal-title":"J. Adv. Trends Basic Appl. Sci."},{"issue":"10","key":"10.1016\/j.tice.2023.102016_bib6","doi-asserted-by":"crossref","first-page":"813","DOI":"10.1038\/sj.bmt.1700980","article-title":"Nephrotoxicity after high-dose carboplatin, etoposide and ifosfamide in germ-cell tumors: incidence and implications for hematologic recovery and clinical outcome","volume":"20","author":"Beyer","year":"1997","journal-title":"Bone Marrow Transplant."},{"issue":"5","key":"10.1016\/j.tice.2023.102016_bib7","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1002\/jcph.23","article-title":"Drug\u2010induced liver injury: The role of drug metabolism and transport","volume":"53","author":"Corsini","year":"2013","journal-title":"J. Clin. Pharmacol."},{"issue":"1","key":"10.1016\/j.tice.2023.102016_bib8","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s12929-019-0499-8","article-title":"Rosmarinus officinalis L.(rosemary) as therapeutic and prophylactic agent","volume":"26","author":"De Oliveira","year":"2019","journal-title":"J. Biomed. Sci."},{"key":"10.1016\/j.tice.2023.102016_bib9","unstructured":"EMA, H., Community herbal monograph on Rosmarinus officinalis L., folium. 2010, EMA\/HMPC\/13633\/2009, 15 July."},{"key":"10.1016\/j.tice.2023.102016_bib10","first-page":"2016","article-title":"The therapeutic potential of rosemary (Rosmarinus officinalis) diterpenes for Alzheimer\u2019s disease","author":"Habtemariam","year":"2016","journal-title":"Evid. -Based Complement. Altern. Med."},{"issue":"4","key":"10.1016\/j.tice.2023.102016_bib11","first-page":"465","article-title":"Protective effect of nutmeg and rosmery on oxidative stress in hypercholesterolaemic rats","volume":"4","author":"Hassanen","year":"2015","journal-title":"Int J. Nutr. Food Sci."},{"issue":"2","key":"10.1016\/j.tice.2023.102016_bib12","first-page":"259","article-title":"Prophylactic effect of Rosemary extract on hormonal disturbances in male Albino rats","volume":"42","author":"Kamal","year":"2010","journal-title":"Isotope Radiat. Res."},{"issue":"11","key":"10.1016\/j.tice.2023.102016_bib13","doi-asserted-by":"crossref","first-page":"1958","DOI":"10.1021\/tx5003063","article-title":"Induction of Pi form of glutathione S-transferase by carnosic acid is mediated through PI3K\/Akt\/NF-\u03baB pathway and protects against neurotoxicity","volume":"27","author":"Lin","year":"2014","journal-title":"Chem. Res. Toxicol."},{"issue":"13","key":"10.1016\/j.tice.2023.102016_bib14","doi-asserted-by":"crossref","first-page":"1574","DOI":"10.1016\/j.phymed.2016.09.010","article-title":"Rosmarinic acid stimulates liver regeneration through the mTOR pathway","volume":"23","author":"Lou","year":"2016","journal-title":"Phytomedicine"},{"issue":"1\u20132","key":"10.1016\/j.tice.2023.102016_bib15","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1016\/S0300-483X(03)00155-0","article-title":"Antioxidant nutrients and alcohol","volume":"189","author":"McDonough","year":"2003","journal-title":"Toxicology"},{"issue":"2","key":"10.1016\/j.tice.2023.102016_bib16","doi-asserted-by":"crossref","first-page":"69","DOI":"10.31586\/Physiology.0302.02","article-title":"The effects of rosemary extract on spermatogenesis and sexual hormones of mice under heat stress","volume":"3","author":"Modaresi","year":"2018","journal-title":"Trends J. Sci. Res."},{"issue":"1","key":"10.1016\/j.tice.2023.102016_bib17","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/2251-6581-13-20","article-title":"Effect of garlic on lipid profile and expression of LXR alpha in intestine and liver of hypercholesterolemic mice","volume":"13","author":"Mohammadi","year":"2014","journal-title":"J. Diabetes Metab. Disord."},{"issue":"1","key":"10.1016\/j.tice.2023.102016_bib18","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1080\/00207450390161903","article-title":"Aromas of rosemary and lavender essential oils differentially affect cognition and mood in healthy adults","volume":"113","author":"Moss","year":"2003","journal-title":"Int. J. Neurosci."},{"issue":"7","key":"10.1016\/j.tice.2023.102016_bib19","doi-asserted-by":"crossref","first-page":"621","DOI":"10.1177\/0748233712462470","article-title":"Effect of coriander on thioacetamide-induced hepatotoxicity in rats","volume":"30","author":"Moustafa","year":"2014","journal-title":"Toxicol. Ind. Health"},{"issue":"10","key":"10.1016\/j.tice.2023.102016_bib20","doi-asserted-by":"crossref","first-page":"946","DOI":"10.1080\/10408398.2010.490883","article-title":"Rosemary and cancer prevention: preclinical perspectives","volume":"51","author":"Ngo","year":"2011","journal-title":"Crit. Rev. Food Sci. Nutr."},{"key":"10.1016\/j.tice.2023.102016_bib21","doi-asserted-by":"crossref","unstructured":"Rahman, T., et al., Oxidative stress and human health. 2012.","DOI":"10.4236\/abb.2012.327123"},{"issue":"2","key":"10.1016\/j.tice.2023.102016_bib22","doi-asserted-by":"crossref","first-page":"373","DOI":"10.12816\/0038260","article-title":"Effects of Rosemary extract supplementation on ethanol induced liver injury in adult male albino rat","volume":"46","author":"Ramadan Samaha","year":"2017","journal-title":"Al-Azhar Med. J."},{"issue":"1","key":"10.1016\/j.tice.2023.102016_bib23","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1093\/ajcp\/28.1.56","article-title":"A colorimetric method for the determination of serum glutamic oxalacetic and glutamic pyruvic transaminases","volume":"28","author":"Reitman","year":"1957","journal-title":"Am. J. Clin. Pathol."},{"issue":"3","key":"10.1016\/j.tice.2023.102016_bib24","doi-asserted-by":"crossref","first-page":"697","DOI":"10.1016\/j.foodchem.2008.02.068","article-title":"Effects of flavonoid-rich extract from seeds of Eugenia jambolana (L.) on carbohydrate and lipid metabolism in diabetic mice","volume":"110","author":"Sharma","year":"2008","journal-title":"Food Chem."},{"issue":"1","key":"10.1016\/j.tice.2023.102016_bib25","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/srep34064","article-title":"Etoposide induced cytotoxicity mediated by ROS and ERK in human kidney proximal tubule cells","volume":"6","author":"Shin","year":"2016","journal-title":"Sci. Rep."},{"issue":"1","key":"10.1016\/j.tice.2023.102016_bib26","doi-asserted-by":"crossref","first-page":"193","DOI":"10.3390\/ijms16010193","article-title":"Oxidative stress and its significant roles in neurodegenerative diseases and cancer","volume":"16","author":"Thanan","year":"2015","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.tice.2023.102016_bib27","doi-asserted-by":"crossref","first-page":"769","DOI":"10.1016\/j.biopha.2018.01.025","article-title":"Rosemary extract modulates fertility potential, DNA fragmentation, injury, KI67 and P53 alterations induced by etoposide in rat testes","volume":"98","author":"Tousson","year":"2018","journal-title":"Biomed. Pharmacother."},{"key":"10.1016\/j.tice.2023.102016_bib28","doi-asserted-by":"crossref","unstructured":"Waller, S., et al., Can the essential oil of rosemary (Rosmarinus officinalis Linn.) protect rats infected with itraconazole-resistant Sporothrix brasiliensis from fungal spread? 2021. 31(4): p. 101199.","DOI":"10.1016\/j.mycmed.2021.101199"},{"issue":"3","key":"10.1016\/j.tice.2023.102016_bib29","doi-asserted-by":"crossref","first-page":"2704","DOI":"10.3390\/molecules17032704","article-title":"Antibacterial activity and anticancer activity of Rosmarinus officinalis L. essential oil compared to that of its main components","volume":"17","author":"Wang","year":"2012","journal-title":"Molecules"},{"issue":"19","key":"10.1016\/j.tice.2023.102016_bib30","doi-asserted-by":"crossref","first-page":"4843","DOI":"10.1021\/acs.jafc.5b01246","article-title":"Carnosic acid as a major bioactive component in rosemary extract ameliorates high-fat-diet-induced obesity and metabolic syndrome in mice","volume":"63","author":"Zhao","year":"2015","journal-title":"J. Agric. Food Chem."},{"issue":"8","key":"10.1016\/j.tice.2023.102016_bib31","doi-asserted-by":"crossref","first-page":"741","DOI":"10.1111\/j.1872-034X.2012.00996.x","article-title":"Oxidative stress and liver disease","volume":"42","author":"Zhu","year":"2012","journal-title":"Hepatol. Res."}],"container-title":["Tissue and Cell"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0040816623000046?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0040816623000046?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,22]],"date-time":"2025-09-22T20:24:50Z","timestamp":1758572690000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0040816623000046"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,4]]},"references-count":31,"alternative-id":["S0040816623000046"],"URL":"https:\/\/doi.org\/10.1016\/j.tice.2023.102016","relation":{},"ISSN":["0040-8166"],"issn-type":[{"type":"print","value":"0040-8166"}],"subject":[],"published":{"date-parts":[[2023,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Rosemary (Rosmarinus officinalis L.) essential oil alleviates testis failure induced by Etoposide in male rats","name":"articletitle","label":"Article Title"},{"value":"Tissue and Cell","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.tice.2023.102016","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"102016"}}