{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T16:24:53Z","timestamp":1792599893859,"version":"4.5.0"},"reference-count":72,"publisher":"Elsevier BV","issue":"8","content-domain":{"domain":["cell.com","bmn.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Trends in Microbiology"],"published-print":{"date-parts":[[2013,8]]},"DOI":"10.1016\/j.tim.2013.06.005","type":"journal-article","created":{"date-parts":[[2013,7,19]],"date-time":"2013-07-19T17:00:45Z","timestamp":1374253245000},"page":"372-379","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":82,"title":["Illuminating the roles of the Borrelia burgdorferi adhesins"],"prefix":"10.1016","volume":"21","author":[{"given":"Jenifer","family":"Coburn","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John","family":"Leong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"George","family":"Chaconas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.tim.2013.06.005_bib0005","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1038\/nrmicro2714","article-title":"Of ticks, mice and men: understanding the dual-host lifestyle of Lyme disease spirochaetes","volume":"10","author":"Radolf","year":"2012","journal-title":"Nat. Rev. Microbiol."},{"key":"10.1016\/j.tim.2013.06.005_bib0010","series-title":"Borrelia: Molecular Biology, Host Interaction, and Pathogenesis","author":"Radolf","year":"2010"},{"key":"10.1016\/j.tim.2013.06.005_bib0015","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1056\/NEJM200107123450207","article-title":"Lyme disease","volume":"345","author":"Steere","year":"2001","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.tim.2013.06.005_bib0020","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1016\/S0140-6736(11)60103-7","article-title":"Lyme borreliosis","volume":"379","author":"Stanek","year":"2012","journal-title":"Lancet"},{"key":"10.1016\/j.tim.2013.06.005_bib0025","doi-asserted-by":"crossref","first-page":"364","DOI":"10.1603\/0022-2585-40.3.364","article-title":"Experimental infection of Ixodes scapularis larvae (Acari: Ixodidae) by immersion in low passage cultures of Borrelia burgdorferi","volume":"40","author":"Policastro","year":"2003","journal-title":"J. Med. Entomol."},{"key":"10.1016\/j.tim.2013.06.005_bib0030","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1093\/infdis\/162.1.133","article-title":"Lyme borreliosis in selected strains and ages of laboratory mice","volume":"162","author":"Barthold","year":"1990","journal-title":"J. Infect. Dis."},{"key":"10.1016\/j.tim.2013.06.005_bib0035","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1097\/00002281-200207000-00011","article-title":"Host-pathogen interactions and the pathogenesis of murine Lyme disease","volume":"14","author":"Weis","year":"2002","journal-title":"Curr. Opin. Rheumatol."},{"key":"10.1016\/j.tim.2013.06.005_bib0040","doi-asserted-by":"crossref","first-page":"350","DOI":"10.1016\/j.tim.2007.06.003","article-title":"Hidden in plain sight: Borrelia burgdorferi and the extracellular matrix","volume":"15","author":"Cabello","year":"2007","journal-title":"Trends Microbiol."},{"key":"10.1016\/j.tim.2013.06.005_bib0045","first-page":"320","article-title":"Borrelia burgdorferi BBB07 interaction with integrin \u03b13\u03b21 stimulates production of pro-inflammatory mediators in primary human chondrocytes","volume":"10","author":"Behera","year":"2008","journal-title":"Cell. Microbiol."},{"key":"10.1016\/j.tim.2013.06.005_bib0050","doi-asserted-by":"crossref","first-page":"3249","DOI":"10.1128\/IAI.05122-11","article-title":"The Borrelia burgdorferi integrin ligand P66 affects gene expression by human cells in culture","volume":"79","author":"LaFrance","year":"2011","journal-title":"Infect. Immun."},{"key":"10.1016\/j.tim.2013.06.005_bib0055","doi-asserted-by":"crossref","first-page":"e5412","DOI":"10.1371\/journal.pone.0005412","article-title":"A novel fibronectin binding motif in MSCRAMMs targets F3 modules","volume":"4","author":"Prabhakaran","year":"2009","journal-title":"PLoS ONE"},{"key":"10.1016\/j.tim.2013.06.005_bib0060","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1038\/nrmicro1086","article-title":"The burgeoning molecular genetics of the Lyme disease spirochaete","volume":"3","author":"Rosa","year":"2005","journal-title":"Nat. Rev."},{"key":"10.1016\/j.tim.2013.06.005_bib0065","doi-asserted-by":"crossref","first-page":"985","DOI":"10.1128\/AEM.02172-09","article-title":"Use of rpsL as a counterselectable marker in Borrelia burgdorferi","volume":"76","author":"Drecktrah","year":"2010","journal-title":"Appl. Environ. Microbiol."},{"key":"10.1016\/j.tim.2013.06.005_bib0070","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.plasmid.2004.10.006","article-title":"The plasmids of Borrelia burgdorferi: essential genetic elements of a pathogen","volume":"53","author":"Stewart","year":"2005","journal-title":"Plasmid"},{"key":"10.1016\/j.tim.2013.06.005_bib0075","doi-asserted-by":"crossref","first-page":"490","DOI":"10.1046\/j.1365-2958.2000.01698.x","article-title":"A bacterial genome in flux: the twelve linear and nine circular extrachromosomal DNAs in an infectious isolate of the Lyme disease spirochete Borrelia burgdorferi","volume":"35","author":"Casjens","year":"2000","journal-title":"Mol. Microbiol."},{"key":"10.1016\/j.tim.2013.06.005_bib0080","doi-asserted-by":"crossref","first-page":"580","DOI":"10.1038\/37551","article-title":"Genomic sequence of a Lyme disease spirochaete, Borrelia burgdorferi","volume":"390","author":"Fraser","year":"1997","journal-title":"Nature"},{"key":"10.1016\/j.tim.2013.06.005_bib0085","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1146\/annurev.micro.112408.134037","article-title":"Structure, function, and evolution of linear replicons in Borrelia","volume":"64","author":"Chaconas","year":"2010","journal-title":"Annu. Rev. Microbiol."},{"key":"10.1016\/j.tim.2013.06.005_bib0090","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1016\/j.mimet.2011.05.004","article-title":"Multiplex PCR as a tool for validating plasmid content of Borrelia burgdorferi","volume":"86","author":"Bunikis","year":"2011","journal-title":"J. Microbiol. Methods"},{"key":"10.1016\/j.tim.2013.06.005_bib0095","doi-asserted-by":"crossref","first-page":"1483","DOI":"10.1128\/AEM.01877-10","article-title":"High-throughput plasmid content analysis of Borrelia burgdorferi B31 by using Luminex multiplex technology","volume":"77","author":"Norris","year":"2011","journal-title":"Appl. Environ. Microbiol."},{"key":"10.1016\/j.tim.2013.06.005_bib0100","doi-asserted-by":"crossref","first-page":"e47532","DOI":"10.1371\/journal.pone.0047532","article-title":"Analysis of an ordered, comprehensive STM mutant library in infectious Borrelia burgdorferi: insights into the genes required for mouse infectivity","volume":"7","author":"Lin","year":"2012","journal-title":"PLoS ONE"},{"key":"10.1016\/j.tim.2013.06.005_bib0105","doi-asserted-by":"crossref","first-page":"7307","DOI":"10.1073\/pnas.1231043100","article-title":"Decorin-binding proteins A and B confer distinct mammalian cell type-specific attachment by Borrelia burgdorferi, the Lyme disease spirochete","volume":"100","author":"Fischer","year":"2003","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1016\/j.tim.2013.06.005_bib0110","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1111\/j.1365-2958.2011.07801.x","article-title":"Bioluminescent imaging of Borrelia burgdorferi in vivo demonstrates that the fibronectin-binding protein BBK32 is required for optimal infectivity","volume":"82","author":"Hyde","year":"2011","journal-title":"Mol. Microbiol."},{"key":"10.1016\/j.tim.2013.06.005_bib0115","doi-asserted-by":"crossref","first-page":"e1000090","DOI":"10.1371\/journal.ppat.1000090","article-title":"Real-time high resolution 3D imaging of the lyme disease spirochete adhering to and escaping from the vasculature of a living host","volume":"4","author":"Moriarty","year":"2008","journal-title":"PLoS Pathog."},{"key":"10.1016\/j.tim.2013.06.005_bib0120","doi-asserted-by":"crossref","first-page":"1116","DOI":"10.1111\/mmi.12045","article-title":"Vascular binding of a pathogen under shear force through mechanistically distinct sequential interactions with host macromolecules","volume":"86","author":"Moriarty","year":"2012","journal-title":"Mol. Microbiol."},{"key":"10.1016\/j.tim.2013.06.005_bib0125","doi-asserted-by":"crossref","first-page":"e1000169","DOI":"10.1371\/journal.ppat.1000169","article-title":"Molecular mechanisms involved in vascular interactions of the Lyme disease pathogen in a living host","volume":"4","author":"Norman","year":"2008","journal-title":"PLoS Pathog."},{"key":"10.1016\/j.tim.2013.06.005_bib0130","doi-asserted-by":"crossref","first-page":"e1002532","DOI":"10.1371\/journal.ppat.1002532","article-title":"Borrelia burgdorferi requires the alternative sigma factor RpoS for dissemination within the vector during tick-to-mammal transmission","volume":"8","author":"Dunham-Ems","year":"2012","journal-title":"PLoS Pathog."},{"key":"10.1016\/j.tim.2013.06.005_bib0135","doi-asserted-by":"crossref","first-page":"3652","DOI":"10.1172\/JCI39401","article-title":"Live imaging reveals a biphasic mode of dissemination of Borrelia burgdorferi within ticks","volume":"119","author":"Dunham-Ems","year":"2009","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.tim.2013.06.005_bib0140","doi-asserted-by":"crossref","first-page":"3059","DOI":"10.1073\/pnas.1114362109","article-title":"The heterogeneous motility of the Lyme disease spirochete in gelatin mimics dissemination through tissue","volume":"109","author":"Harman","year":"2012","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1016\/j.tim.2013.06.005_bib0145","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1038\/ni.1855","article-title":"An intravascular immune response to Borrelia burgdorferi involves Kupffer cells and iNKT cells","volume":"11","author":"Lee","year":"2010","journal-title":"Nat. Immunol."},{"key":"10.1016\/j.tim.2013.06.005_bib0150","doi-asserted-by":"crossref","first-page":"262","DOI":"10.1111\/j.1365-2958.2007.05924.x","article-title":"Borrelia burgdorferi adhesins identified using in vivo phage display","volume":"66","author":"Antonara","year":"2007","journal-title":"Mol. Microbiol."},{"key":"10.1016\/j.tim.2013.06.005_bib0155","doi-asserted-by":"crossref","first-page":"926","DOI":"10.1046\/j.1365-2958.1999.01654.x","article-title":"Characterization of a candidate Borrelia burgdorferi \u03b23-chain integrin ligand identified using a phage display library","volume":"34","author":"Coburn","year":"1999","journal-title":"Mol. Microbiol."},{"key":"10.1016\/j.tim.2013.06.005_bib0160","doi-asserted-by":"crossref","first-page":"711","DOI":"10.1046\/j.1365-2958.1998.01103.x","article-title":"Decorin-binding adhesins from Borrelia burgdorferi","volume":"30","author":"Guo","year":"1998","journal-title":"Mol. Microbiol."},{"key":"10.1016\/j.tim.2013.06.005_bib0165","doi-asserted-by":"crossref","first-page":"3467","DOI":"10.1128\/IAI.63.9.3467-3472.1995","article-title":"Adherence of Borrelia burgdorferi to the proteoglycan decorin","volume":"63","author":"Guo","year":"1995","journal-title":"Infect. Immun."},{"key":"10.1016\/j.tim.2013.06.005_bib0170","doi-asserted-by":"crossref","first-page":"1220","DOI":"10.1046\/j.1365-2958.2000.01792.x","article-title":"Identification of a candidate glycosaminoglycan-binding adhesin of the Lyme disease spirochete Borrelia burgdorferi","volume":"35","author":"Parveen","year":"2000","journal-title":"Mol. Microbiol."},{"key":"10.1016\/j.tim.2013.06.005_bib0175","doi-asserted-by":"crossref","first-page":"1003","DOI":"10.1046\/j.1365-2958.1998.01127.x","article-title":"Identification of a 47kDa fibronectin-binding protein expressed by Borrelia burgdorferi isolate B31","volume":"30","author":"Probert","year":"1998","journal-title":"Mol. Microbiol."},{"key":"10.1016\/j.tim.2013.06.005_bib0180","doi-asserted-by":"crossref","first-page":"845","DOI":"10.1172\/JCI11692","article-title":"Resistance to Lyme disease in decorin-deficient mice","volume":"107","author":"Brown","year":"2001","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.tim.2013.06.005_bib0185","doi-asserted-by":"crossref","first-page":"3501","DOI":"10.1128\/IAI.00163-11","article-title":"Allelic variation of the Lyme disease spirochete adhesin DbpA influences spirochetal binding to decorin, dermatan sulfate, and mammalian cells","volume":"79","author":"Benoit","year":"2011","journal-title":"Infect. Immun."},{"key":"10.1016\/j.tim.2013.06.005_bib0190","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1128\/IAI.74.1.435-441.2006","article-title":"Fibronectin binding protein BBK32 of the Lyme disease spirochete promotes bacterial attachment to glycosaminoglycans","volume":"74","author":"Fischer","year":"2006","journal-title":"Infect. Immun."},{"key":"10.1016\/j.tim.2013.06.005_bib0195","doi-asserted-by":"crossref","first-page":"1591","DOI":"10.1111\/j.1365-2958.2005.05042.x","article-title":"Inactivation of the fibronectin-binding adhesin gene bbk32 significantly attenuates the infectivity potential of Borrelia burgdorferi","volume":"59","author":"Seshu","year":"2006","journal-title":"Mol. Microbiol."},{"key":"10.1016\/j.tim.2013.06.005_bib0200","doi-asserted-by":"crossref","first-page":"1663","DOI":"10.1128\/IAI.01359-12","article-title":"The early dissemination defect attributed to disruption of decorin-binding proteins is abolished in chronic murine Lyme borreliosis","volume":"81","author":"Imai","year":"2013","journal-title":"Infect. Immun."},{"key":"10.1016\/j.tim.2013.06.005_bib0205","doi-asserted-by":"crossref","first-page":"5694","DOI":"10.1128\/IAI.00690-08","article-title":"Borrelia burgdorferi lacking DbpBA exhibits an early survival defect during experimental infection","volume":"76","author":"Weening","year":"2008","journal-title":"Infect. Immun."},{"key":"10.1016\/j.tim.2013.06.005_bib0210","doi-asserted-by":"crossref","first-page":"3305","DOI":"10.1128\/IAI.02035-05","article-title":"Borrelia burgdorferi lacking BBK32, a fibronectin-binding protein, retains full pathogenicity","volume":"74","author":"Li","year":"2006","journal-title":"Infect. Immun."},{"key":"10.1016\/j.tim.2013.06.005_bib0215","doi-asserted-by":"crossref","first-page":"2802","DOI":"10.1128\/IAI.00227-09","article-title":"Borrelia burgdorferi RevA antigen binds host fibronectin","volume":"77","author":"Brissette","year":"2009","journal-title":"Infect. Immun."},{"key":"10.1016\/j.tim.2013.06.005_bib0220","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1146\/annurev.micro.112408.134040","article-title":"Gene regulation in Borrelia burgdorferi","volume":"65","author":"Samuels","year":"2011","journal-title":"Annu. Rev. Microbiol."},{"key":"10.1016\/j.tim.2013.06.005_bib0225","doi-asserted-by":"crossref","first-page":"7301","DOI":"10.1073\/pnas.1131117100","article-title":"Targeted mutation of the outer membrane protein P66 disrupts attachment of the Lyme disease spirochete, Borrelia burgdorferi, to integrin \u03b1v\u03b23","volume":"100","author":"Coburn","year":"2003","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1016\/j.tim.2013.06.005_bib0230","doi-asserted-by":"crossref","first-page":"1105","DOI":"10.1111\/j.1365-2958.2012.08160.x","article-title":"The \u03b23-integrin ligand of Borrelia burgdorferi is critical for infection of mice but not ticks","volume":"85","author":"Ristow","year":"2012","journal-title":"Mol. Microbiol."},{"key":"10.1016\/j.tim.2013.06.005_bib0235","doi-asserted-by":"crossref","first-page":"3142","DOI":"10.1073\/pnas.0306845101","article-title":"Outer-surface protein C of the Lyme disease spirochete: a protein induced in ticks for infection of mammals","volume":"101","author":"Grimm","year":"2004","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1016\/j.tim.2013.06.005_bib0240","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1186\/1471-2180-8-82","article-title":"Assessment of decorin-binding protein A to the infectivity of Borrelia burgdorferi in the murine models of needle and tick infection","volume":"8","author":"Blevins","year":"2008","journal-title":"BMC Microbiol."},{"key":"10.1016\/j.tim.2013.06.005_bib0245","doi-asserted-by":"crossref","first-page":"492","DOI":"10.1128\/IAI.62.2.492-500.1994","article-title":"Heritable susceptibility to severe Borrelia burgdorferi-induced arthritis is dominant and is associated with persistence of large numbers of spirochetes in tissues","volume":"62","author":"Yang","year":"1994","journal-title":"Infect. Immun."},{"key":"10.1016\/j.tim.2013.06.005_bib0250","doi-asserted-by":"crossref","first-page":"678","DOI":"10.1038\/nri2156","article-title":"Getting to the site of inflammation: the leukocyte adhesion cascade updated","volume":"7","author":"Ley","year":"2007","journal-title":"Nat. Rev. Immunol."},{"key":"10.1016\/j.tim.2013.06.005_bib0255","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1016\/j.cell.2004.10.027","article-title":"TROSPA, an Ixodes scapularis receptor for Borrelia burgdorferi","volume":"119","author":"Pal","year":"2004","journal-title":"Cell"},{"key":"10.1016\/j.tim.2013.06.005_bib0260","doi-asserted-by":"crossref","first-page":"5228","DOI":"10.1128\/IAI.00410-08","article-title":"Outer surface protein A protects Lyme disease spirochetes from acquired host immunity in the tick vector","volume":"76","author":"Battisti","year":"2008","journal-title":"Infect. Immun."},{"key":"10.1016\/j.tim.2013.06.005_bib0265","doi-asserted-by":"crossref","first-page":"641","DOI":"10.1084\/jem.20031960","article-title":"Essential role for OspA\/B in the life cycle of the Lyme disease spirochete","volume":"199","author":"Yang","year":"2004","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.tim.2013.06.005_bib0270","doi-asserted-by":"crossref","first-page":"573","DOI":"10.1038\/nature03812","article-title":"The Lyme disease agent exploits a tick protein to infect the mammalian host","volume":"436","author":"Ramamoorthi","year":"2005","journal-title":"Nature"},{"key":"10.1016\/j.tim.2013.06.005_bib0275","doi-asserted-by":"crossref","first-page":"1517","DOI":"10.1128\/IAI.01725-06","article-title":"Rapid clearance of Lyme disease spirochetes lacking OspC from skin","volume":"75","author":"Tilly","year":"2007","journal-title":"Infect. Immun."},{"key":"10.1016\/j.tim.2013.06.005_bib0280","doi-asserted-by":"crossref","first-page":"3554","DOI":"10.1128\/IAI.01950-05","article-title":"Borrelia burgdorferi OspC protein required exclusively in a crucial early stage of mammalian infection","volume":"74","author":"Tilly","year":"2006","journal-title":"Infect. Immun."},{"key":"10.1016\/j.tim.2013.06.005_bib0285","doi-asserted-by":"crossref","first-page":"3847","DOI":"10.4049\/jimmunol.169.7.3847","article-title":"Complement inhibitor factor H binding to Lyme disease spirochetes is mediated by inducible expression of multiple plasmid-encoded outer surface protein E paralogs","volume":"169","author":"Alitalo","year":"2002","journal-title":"J. Immunol."},{"key":"10.1016\/j.tim.2013.06.005_bib0290","doi-asserted-by":"crossref","first-page":"8427","DOI":"10.1074\/jbc.M007994200","article-title":"The complement regulator factor H binds to the surface protein OspE of Borrelia burgdorferi","volume":"276","author":"Hellwage","year":"2001","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.tim.2013.06.005_bib0295","doi-asserted-by":"crossref","first-page":"3587","DOI":"10.1128\/IAI.71.6.3587-3596.2003","article-title":"Analysis of the OspE determinants involved in binding of factor H and OspE-targeting antibodies elicited during Borrelia burgdorferi infection in mice","volume":"71","author":"Metts","year":"2003","journal-title":"Infect. Immun."},{"key":"10.1016\/j.tim.2013.06.005_bib0300","doi-asserted-by":"crossref","first-page":"490","DOI":"10.1086\/653825","article-title":"Complement regulator-acquiring surface protein 1 of Borrelia burgdorferi binds to human bone morphogenic protein 2, several extracellular matrix proteins, and plasminogen","volume":"202","author":"Hallstrom","year":"2010","journal-title":"J. Infect. Dis."},{"key":"10.1016\/j.tim.2013.06.005_bib0305","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1128\/IAI.01133-08","article-title":"Borrelia burgdorferi infection-associated surface proteins ErpP, ErpA, and ErpC bind human plasminogen","volume":"77","author":"Brissette","year":"2009","journal-title":"Infect. Immun."},{"key":"10.1016\/j.tim.2013.06.005_bib0310","doi-asserted-by":"crossref","first-page":"18803","DOI":"10.1074\/jbc.M501731200","article-title":"Borrelia burgdorferi binds fibronectin through a tandem beta-zipper, a common mechanism of fibronectin binding in staphylococci, streptococci, and spirochetes","volume":"280","author":"Raibaud","year":"2005","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.tim.2013.06.005_bib0315","doi-asserted-by":"crossref","first-page":"41706","DOI":"10.1074\/jbc.M401691200","article-title":"BBK32, a fibronectin binding MSCRAMM from Borrelia burgdorferi, contains a disordered region that undergoes a conformational change on ligand binding","volume":"279","author":"Kim","year":"2004","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.tim.2013.06.005_bib0320","doi-asserted-by":"crossref","first-page":"4129","DOI":"10.1128\/IAI.69.6.4129-4133.2001","article-title":"Mapping the ligand-binding region of the Borrelia burgdorferi fibronectin-binding protein BBK32","volume":"69","author":"Probert","year":"2001","journal-title":"Infect. Immun."},{"key":"10.1016\/j.tim.2013.06.005_bib0325","doi-asserted-by":"crossref","first-page":"3016","DOI":"10.1128\/IAI.74.5.3016-3020.2006","article-title":"Bgp, a secreted glycosaminoglycan-binding protein of Borrelia burgdorferi strain N40, displays nucleosidase activity and is not essential for infection of immunodeficient mice","volume":"74","author":"Parveen","year":"2006","journal-title":"Infect. Immun."},{"key":"10.1016\/j.tim.2013.06.005_bib0330","doi-asserted-by":"crossref","first-page":"863","DOI":"10.1099\/mic.0.024604-0","article-title":"The Borrelia burgdorferi outer-surface protein ErpX binds mammalian laminin","volume":"155","author":"Brissette","year":"2009","journal-title":"Microbiology"},{"key":"10.1016\/j.tim.2013.06.005_bib0335","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1111\/j.1365-2958.2008.06264.x","article-title":"Essential protective role attributed to the surface lipoproteins of Borrelia burgdorferi against innate defences","volume":"69","author":"Xu","year":"2008","journal-title":"Mol. Microbiol."},{"key":"10.1016\/j.tim.2013.06.005_bib0340","doi-asserted-by":"crossref","first-page":"1547","DOI":"10.1111\/j.1365-2958.2007.05895.x","article-title":"The role of VlsE antigenic variation in the Lyme disease spirochete: persistence through a mechanism that differs from other pathogens","volume":"65","author":"Bankhead","year":"2007","journal-title":"Mol. Microbiol."},{"key":"10.1016\/j.tim.2013.06.005_bib0345","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1016\/S0092-8674(00)80206-8","article-title":"Antigenic variation in Lyme disease borreliae by promiscuous recombination of VMP-like sequence cassettes","volume":"89","author":"Zhang","year":"1997","journal-title":"Cell"},{"key":"10.1016\/j.tim.2013.06.005_bib0350","doi-asserted-by":"crossref","first-page":"1319","DOI":"10.1111\/j.1365-2958.2006.05204.x","article-title":"Antigenic variation with a twist \u2013 the Borrelia story","volume":"60","author":"Norris","year":"2006","journal-title":"Mol. Microbiol."},{"key":"10.1016\/j.tim.2013.06.005_bib0355","doi-asserted-by":"crossref","first-page":"4477","DOI":"10.1128\/IAI.00501-10","article-title":"Characterization of unique regions of Borrelia burgdorferi surface-located membrane protein 1","volume":"78","author":"Yang","year":"2010","journal-title":"Infect. Immun."},{"key":"10.1016\/j.tim.2013.06.005_bib0360","doi-asserted-by":"crossref","first-page":"e1000326","DOI":"10.1371\/journal.ppat.1000326","article-title":"A chromosomally encoded virulence factor protects the Lyme disease pathogen against host-adaptive immunity","volume":"5","author":"Yang","year":"2009","journal-title":"PLoS Pathog."}],"container-title":["Trends in Microbiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0966842X13001145?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0966842X13001145?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2020,7,31]],"date-time":"2020-07-31T04:31:03Z","timestamp":1596169863000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0966842X13001145"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,8]]},"references-count":72,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2013,8]]}},"alternative-id":["S0966842X13001145"],"URL":"https:\/\/doi.org\/10.1016\/j.tim.2013.06.005","relation":{},"ISSN":["0966-842X"],"issn-type":[{"value":"0966-842X","type":"print"}],"subject":[],"published":{"date-parts":[[2013,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Illuminating the roles of the Borrelia burgdorferi adhesins","name":"articletitle","label":"Article Title"},{"value":"Trends in Microbiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.tim.2013.06.005","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2013 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}