{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,23]],"date-time":"2026-04-23T03:33:38Z","timestamp":1776915218274,"version":"3.51.2"},"reference-count":10,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2023,5,1]],"date-time":"2023-05-01T00:00:00Z","timestamp":1682899200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,5,1]],"date-time":"2023-05-01T00:00:00Z","timestamp":1682899200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,4,17]],"date-time":"2024-04-17T00:00:00Z","timestamp":1713312000000},"content-version":"am","delay-in-days":352,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,5,1]],"date-time":"2023-05-01T00:00:00Z","timestamp":1682899200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2023,5,1]],"date-time":"2023-05-01T00:00:00Z","timestamp":1682899200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2023,5,1]],"date-time":"2023-05-01T00:00:00Z","timestamp":1682899200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2023,5,1]],"date-time":"2023-05-01T00:00:00Z","timestamp":1682899200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2023,5,1]],"date-time":"2023-05-01T00:00:00Z","timestamp":1682899200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["bmn.com","cell.com","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Trends in Microbiology"],"published-print":{"date-parts":[[2023,5]]},"DOI":"10.1016\/j.tim.2023.02.013","type":"journal-article","created":{"date-parts":[[2023,3,6]],"date-time":"2023-03-06T16:08:23Z","timestamp":1678118903000},"page":"423-425","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"title":["Pathogen-defending deubiquitinase possesses distinct specificity towards K6-polyubiquitination"],"prefix":"10.1016","volume":"31","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4566-5199","authenticated-orcid":false,"given":"Zhengrui","family":"Zhang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chittaranjan","family":"Das","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.tim.2023.02.013_bb0005","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1038\/cr.2016.39","article-title":"Ubiquitin modifications","volume":"26","author":"Swatek","year":"2016","journal-title":"Cell Res."},{"key":"10.1016\/j.tim.2023.02.013_bb0010","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1146\/annurev-micro-041020-025803","article-title":"Regulation of host\u2013pathogen interactions via the ubiquitin system","volume":"76","author":"Mukherjee","year":"2022","journal-title":"Annu. Rev. Microbiol."},{"key":"10.1016\/j.tim.2023.02.013_bb0015","doi-asserted-by":"crossref","DOI":"10.3389\/fmicb.2021.790442","article-title":"Exploitation of the host ubiquitin system: means by Legionella pneumophila","volume":"12","author":"Luo","year":"2021","journal-title":"Front. Microbiol."},{"key":"10.1016\/j.tim.2023.02.013_bb0020","doi-asserted-by":"crossref","DOI":"10.1111\/cmi.12840","article-title":"LotA, a Legionella deubiquitinase, has dual catalytic activity and contributes to intracellular growth","volume":"20","author":"Kubori","year":"2018","journal-title":"Cell. Microbiol."},{"key":"10.1016\/j.tim.2023.02.013_bb0025","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/j.molcel.2022.11.022","article-title":"Mechanism of Lys6 poly-ubiquitin specificity by the L. pneumophila deubiquitinase LotA","volume":"83","author":"Warren","year":"2023","journal-title":"Mol. Cell"},{"key":"10.1016\/j.tim.2023.02.013_bb0030","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1074\/jbc.M110.167643","article-title":"Biochemical and structural studies of a HECT-like ubiquitin ligase from Escherichia coli O157:H7","volume":"286","author":"Lin","year":"2011","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.tim.2023.02.013_bb0035","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1038\/nprot.2015.018","article-title":"Deubiquitinase-based analysis of ubiquitin chain architecture using ubiquitin chain restriction (UbiCRest)","volume":"10","author":"Hospenthal","year":"2015","journal-title":"Nat. Protoc."},{"key":"10.1016\/j.tim.2023.02.013_bb0040","article-title":"Structural insights into ubiquitin chain cleavage by Legionella ovarian tumor deubiquitinases","author":"Kang","year":"2023","journal-title":"bioRxiv"},{"key":"10.1016\/j.tim.2023.02.013_bb0045","doi-asserted-by":"crossref","DOI":"10.1016\/j.jbc.2022.102414","article-title":"Structural basis for the dual catalytic activity of the Legionella pneumophila ovarian tumor (OTU) domain deubiquitinase LotA","volume":"298","author":"Luo","year":"2022","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.tim.2023.02.013_bb0050","doi-asserted-by":"crossref","first-page":"1312","DOI":"10.1016\/j.cell.2013.05.014","article-title":"OTULIN antagonizes LUBAC signaling by specifically hydrolyzing Met1-linked polyubiquitin","volume":"153","author":"Keusekotten","year":"2013","journal-title":"Cell"}],"container-title":["Trends in Microbiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0966842X23000616?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0966842X23000616?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,18]],"date-time":"2025-10-18T18:47:18Z","timestamp":1760813238000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0966842X23000616"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,5]]},"references-count":10,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2023,5]]}},"alternative-id":["S0966842X23000616"],"URL":"https:\/\/doi.org\/10.1016\/j.tim.2023.02.013","relation":{},"ISSN":["0966-842X"],"issn-type":[{"value":"0966-842X","type":"print"}],"subject":[],"published":{"date-parts":[[2023,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Pathogen-defending deubiquitinase possesses distinct specificity towards K6-polyubiquitination","name":"articletitle","label":"Article Title"},{"value":"Trends in Microbiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.tim.2023.02.013","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}