{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,20]],"date-time":"2026-08-20T15:44:48Z","timestamp":1787240688906,"version":"build-2736575974"},"reference-count":73,"publisher":"Elsevier BV","issue":"12","license":[{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,12,3]],"date-time":"2025-12-03T00:00:00Z","timestamp":1764720000000},"content-version":"am","delay-in-days":367,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/100000060","name":"NIAID","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000060","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100018268","name":"Children's Miracle Network Hospitals","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100018268","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R01 DE032623"],"award-info":[{"award-number":["R01 DE032623"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["U01 CA275310"],"award-info":[{"award-number":["U01 CA275310"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.fr","clinicalkey.jp","clinicalkey.es","clinicalkey.com.au","bmn.com","clinicalkey.com","cell.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Trends in Microbiology"],"published-print":{"date-parts":[[2024,12]]},"DOI":"10.1016\/j.tim.2024.05.007","type":"journal-article","created":{"date-parts":[[2024,6,12]],"date-time":"2024-06-12T19:29:22Z","timestamp":1718220562000},"page":"1179-1189","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"title":["KAP1\/TRIM28 \u2013 antiviral and proviral protagonist of herpesvirus biology"],"prefix":"10.1016","volume":"32","author":[{"given":"Sumita","family":"Bhaduri-McIntosh","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Beth A.","family":"Rousseau","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.tim.2024.05.007_bb0005","doi-asserted-by":"crossref","first-page":"2067","DOI":"10.1101\/gad.10.16.2067","article-title":"KAP-1, a novel corepressor for the highly conserved KRAB repression domain","volume":"10","author":"Friedman","year":"1996","journal-title":"Genes Dev."},{"key":"10.1016\/j.tim.2024.05.007_bb0010","doi-asserted-by":"crossref","first-page":"15299","DOI":"10.1073\/pnas.93.26.15299","article-title":"A novel member of the RING finger family, KRIP-1, associates with the KRAB-A transcriptional repressor domain of zinc finger proteins","volume":"93","author":"Kim","year":"1996","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.tim.2024.05.007_bb0015","doi-asserted-by":"crossref","first-page":"4859","DOI":"10.1093\/nar\/24.24.4859","article-title":"Transcriptional repression by RING finger protein TIF1 beta that interacts with the KRAB repressor domain of KOX1","volume":"24","author":"Moosmann","year":"1996","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.tim.2024.05.007_bb0020","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1038\/nature08674","article-title":"KAP1 controls endogenous retroviruses in embryonic stem cells","volume":"463","author":"Rowe","year":"2010","journal-title":"Nature"},{"key":"10.1016\/j.tim.2024.05.007_bb0025","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pgen.1000325","article-title":"Adaptive evolution in zinc finger transcription factors","volume":"5","author":"Emerson","year":"2009","journal-title":"PLoS Genet."},{"key":"10.1016\/j.tim.2024.05.007_bb0030","doi-asserted-by":"crossref","first-page":"6385","DOI":"10.1093\/emboj\/18.22.6385","article-title":"Interaction with members of the heterochromatin protein 1 (HP1) family and histone deacetylation are differentially involved in transcriptional silencing by members of the TIF1 family","volume":"18","author":"Nielsen","year":"1999","journal-title":"EMBO J."},{"key":"10.1016\/j.tim.2024.05.007_bb0035","doi-asserted-by":"crossref","first-page":"4366","DOI":"10.1128\/MCB.19.6.4366","article-title":"KAP-1 corepressor protein interacts and colocalizes with heterochromatic and euchromatic HP1 proteins: a potential role for Kruppel-associated box-zinc finger proteins in heterochromatin-mediated gene silencing","volume":"19","author":"Ryan","year":"1999","journal-title":"Mol. Cell. Biol."},{"key":"10.1016\/j.tim.2024.05.007_bb0040","doi-asserted-by":"crossref","first-page":"919","DOI":"10.1101\/gad.973302","article-title":"SETDB1: a novel KAP-1-associated histone H3, lysine 9-specific methyltransferase that contributes to HP1-mediated silencing of euchromatic genes by KRAB zinc-finger proteins","volume":"16","author":"Schultz","year":"2002","journal-title":"Genes Dev."},{"key":"10.1016\/j.tim.2024.05.007_bb0045","doi-asserted-by":"crossref","first-page":"428","DOI":"10.1101\/gad.869501","article-title":"Targeting histone deacetylase complexes via KRAB-zinc finger proteins: the PHD and bromodomains of KAP-1 form a cooperative unit that recruits a novel isoform of the Mi-2alpha subunit of NuRD","volume":"15","author":"Schultz","year":"2001","journal-title":"Genes Dev."},{"key":"10.1016\/j.tim.2024.05.007_bb0050","doi-asserted-by":"crossref","first-page":"2147","DOI":"10.1101\/gad.302904","article-title":"Association of the transcriptional corepressor TIF1beta with heterochromatin protein 1 (HP1): an essential role for progression through differentiation","volume":"18","author":"Cammas","year":"2004","journal-title":"Genes Dev."},{"key":"10.1016\/j.tim.2024.05.007_bb0055","doi-asserted-by":"crossref","first-page":"2955","DOI":"10.1242\/dev.127.13.2955","article-title":"Mice lacking the transcriptional corepressor TIF1beta are defective in early postimplantation development","volume":"127","author":"Cammas","year":"2000","journal-title":"Development"},{"key":"10.1016\/j.tim.2024.05.007_bb0060","doi-asserted-by":"crossref","first-page":"837","DOI":"10.1101\/gad.1769609","article-title":"A genome-wide RNAi screen identifies a new transcriptional module required for self-renewal","volume":"23","author":"Hu","year":"2009","journal-title":"Genes Dev."},{"key":"10.1016\/j.tim.2024.05.007_bb0065","doi-asserted-by":"crossref","first-page":"818","DOI":"10.1016\/j.neuron.2008.09.036","article-title":"KAP1-mediated epigenetic repression in the forebrain modulates behavioral vulnerability to stress","volume":"60","author":"Jakobsson","year":"2008","journal-title":"Neuron"},{"key":"10.1016\/j.tim.2024.05.007_bb0070","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1016\/j.devcel.2008.08.014","article-title":"A maternal-zygotic effect gene, Zfp57, maintains both maternal and paternal imprints","volume":"15","author":"Li","year":"2008","journal-title":"Dev. Cell"},{"key":"10.1016\/j.tim.2024.05.007_bb0075","doi-asserted-by":"crossref","first-page":"580","DOI":"10.1038\/ncb1864","article-title":"KRAB-type zinc-finger protein Apak specifically regulates p53-dependent apoptosis","volume":"11","author":"Tian","year":"2009","journal-title":"Nat. Cell Biol."},{"key":"10.1016\/j.tim.2024.05.007_bb0080","doi-asserted-by":"crossref","first-page":"757","DOI":"10.1016\/S1097-2765(00)00075-7","article-title":"Sequence-specific transcriptional corepressor function for BRCA1 through a novel zinc finger protein, ZBRK1","volume":"6","author":"Zheng","year":"2000","journal-title":"Mol. Cell"},{"key":"10.1016\/j.tim.2024.05.007_bb0085","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1042\/BJ20101748","article-title":"The novel Nrf2-interacting factor KAP1 regulates susceptibility to oxidative stress by promoting the Nrf2-mediated cytoprotective response","volume":"436","author":"Maruyama","year":"2011","journal-title":"Biochem. J."},{"key":"10.1016\/j.tim.2024.05.007_bb0090","doi-asserted-by":"crossref","first-page":"15685","DOI":"10.1074\/jbc.M910152199","article-title":"A broad role for the zinc finger protein ZNF202 in human lipid metabolism","volume":"275","author":"Wagner","year":"2000","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.tim.2024.05.007_bb0095","doi-asserted-by":"crossref","first-page":"846","DOI":"10.3390\/v13050846","article-title":"Inflammasome, the constitutive heterochromatin machinery, and replication of an oncogenic herpesvirus","volume":"13","author":"Bhaduri-McIntosh","year":"2021","journal-title":"Viruses"},{"key":"10.1016\/j.tim.2024.05.007_bb0100","doi-asserted-by":"crossref","DOI":"10.1128\/jvi.01028-22","article-title":"IFI16 Partners with KAP1 to maintain Epstein\u2013Barr virus latency","volume":"96","author":"Xu","year":"2022","journal-title":"J. Virol."},{"key":"10.1016\/j.tim.2024.05.007_bb0105","doi-asserted-by":"crossref","first-page":"308","DOI":"10.4331\/wjbc.v5.i3.308","article-title":"KAPtain in charge of multiple missions: emerging roles of KAP1","volume":"5","author":"Cheng","year":"2014","journal-title":"World J. Biol. Chem."},{"key":"10.1016\/j.tim.2024.05.007_bb0110","doi-asserted-by":"crossref","DOI":"10.26508\/lsa.201900349","article-title":"KAP1 is an antiparallel dimer with a functional asymmetry","volume":"2","author":"Fonti","year":"2019","journal-title":"Life Sci. Alliance"},{"key":"10.1016\/j.tim.2024.05.007_bb0115","doi-asserted-by":"crossref","first-page":"15042","DOI":"10.1073\/pnas.1901318116","article-title":"Structure of KAP1 tripartite motif identifies molecular interfaces required for retroelement silencing","volume":"116","author":"Stoll","year":"2019","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.tim.2024.05.007_bb0120","doi-asserted-by":"crossref","first-page":"2229","DOI":"10.3389\/fimmu.2018.02229","article-title":"Phosphorylation of TRIM28 enhances the expression of IFN-beta and proinflammatory cytokines during HPAIV infection of human lung epithelial cells","volume":"9","author":"Krischuns","year":"2018","journal-title":"Front. Immunol."},{"key":"10.1016\/j.tim.2024.05.007_bb0125","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1016\/j.virol.2018.01.012","article-title":"Characterization of interaction between Trim28 and YY1 in silencing proviral DNA of Moloney murine leukemia virus","volume":"516","author":"Lee","year":"2018","journal-title":"Virology"},{"key":"10.1016\/j.tim.2024.05.007_bb0130","doi-asserted-by":"crossref","first-page":"17399","DOI":"10.1073\/pnas.1907031116","article-title":"An influenza virus-triggered SUMO switch orchestrates co-opted endogenous retroviruses to stimulate host antiviral immunity","volume":"116","author":"Schmidt","year":"2019","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.tim.2024.05.007_bb0135","doi-asserted-by":"crossref","first-page":"7481","DOI":"10.3390\/ijms22147481","article-title":"COVID-19 in children: expressions of Type I\/II\/III interferons, TRIM28, SETDB1, and endogenous retroviruses in mild and severe cases","volume":"22","author":"Tovo","year":"2021","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.tim.2024.05.007_bb0140","doi-asserted-by":"crossref","DOI":"10.1016\/j.cellsig.2021.110064","article-title":"TRIM28 regulates SARS-CoV-2 cell entry by targeting ACE2","volume":"85","author":"Wang","year":"2021","journal-title":"Cell. Signal."},{"key":"10.1016\/j.tim.2024.05.007_bb0145","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1186\/s12977-021-00584-y","article-title":"Trim28 acts as restriction factor of prototype foamy virus replication by modulating H3K9me3 marks and destabilizing the viral transactivator Tas","volume":"18","author":"Yuan","year":"2021","journal-title":"Retrovirology"},{"key":"10.1016\/j.tim.2024.05.007_bb0150","doi-asserted-by":"crossref","DOI":"10.1371\/journal.ppat.1008834","article-title":"Genome-wide CRISPR knockout screen identifies ZNF304 as a silencer of HIV transcription that promotes viral latency","volume":"16","author":"Krasnopolsky","year":"2020","journal-title":"PLoS Pathog."},{"key":"10.1016\/j.tim.2024.05.007_bb0155","doi-asserted-by":"crossref","first-page":"3562","DOI":"10.1016\/j.febslet.2012.08.010","article-title":"ZBRK1 represses HIV-1 LTR-mediated transcription","volume":"586","author":"Nishitsuji","year":"2012","journal-title":"FEBS Lett."},{"key":"10.1016\/j.tim.2024.05.007_bb0160","doi-asserted-by":"crossref","first-page":"2019","DOI":"10.1016\/j.febslet.2015.06.013","article-title":"ZNF10 inhibits HIV-1 LTR activity through interaction with NF-kappaB and Sp1 binding motifs","volume":"589","author":"Nishitsuji","year":"2015","journal-title":"FEBS Lett."},{"key":"10.1016\/j.tim.2024.05.007_bb0165","doi-asserted-by":"crossref","first-page":"2282","DOI":"10.1073\/pnas.1819386116","article-title":"Apobec3A maintains HIV-1 latency through recruitment of epigenetic silencing machinery to the long terminal repeat","volume":"116","author":"Taura","year":"2019","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.tim.2024.05.007_bb0170","doi-asserted-by":"crossref","DOI":"10.7554\/eLife.42426","article-title":"TRIM28 promotes HIV-1 latency by SUMOylating CDK9 and inhibiting P-TEFb","volume":"8","author":"Ma","year":"2019","journal-title":"Elife"},{"key":"10.1016\/j.tim.2024.05.007_bb0175","doi-asserted-by":"crossref","first-page":"2692","DOI":"10.1038\/s41598-021-82164-w","article-title":"Inhibition of HIV-1 gene transcription by KAP1 in myeloid lineage","volume":"11","author":"Ait-Ammar","year":"2021","journal-title":"Sci. Rep."},{"key":"10.1016\/j.tim.2024.05.007_bb0180","doi-asserted-by":"crossref","DOI":"10.3389\/fcimb.2022.834636","article-title":"KAP1\/TRIM28: transcriptional activator and\/or repressor of viral and cellular programs?","volume":"12","author":"Randolph","year":"2022","journal-title":"Front. Cell. Infect. Microbiol."},{"key":"10.1016\/j.tim.2024.05.007_bb0185","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/j.molcel.2015.11.004","article-title":"KAP1 Recruitment of the 7SK snRNP complex to promoters enables transcription elongation by RNA polymerase II","volume":"61","author":"McNamara","year":"2016","journal-title":"Mol. Cell"},{"key":"10.1016\/j.tim.2024.05.007_bb0190","doi-asserted-by":"crossref","first-page":"116","DOI":"10.3390\/v16010116","article-title":"Functional analysis of KAP1\/TRIM28 requirements for HIV-1 transcription activation","volume":"16","author":"Randolph","year":"2024","journal-title":"Viruses"},{"key":"10.1016\/j.tim.2024.05.007_bb0195","doi-asserted-by":"crossref","first-page":"699","DOI":"10.18632\/oncotarget.27487","article-title":"DNA dependent protein kinase (DNA-PK) enhances HIV transcription by promoting RNA polymerase II activity and recruitment of transcription machinery at HIV LTR","volume":"11","author":"Zicari","year":"2020","journal-title":"Oncotarget"},{"key":"10.1016\/j.tim.2024.05.007_bb0200","doi-asserted-by":"crossref","first-page":"444","DOI":"10.1038\/s41586-021-03589-x","article-title":"Shape of promoter antisense RNAs regulates ligand-induced transcription activation","volume":"595","author":"Yang","year":"2021","journal-title":"Nature"},{"key":"10.1016\/j.tim.2024.05.007_bb0205","doi-asserted-by":"crossref","first-page":"316","DOI":"10.1038\/s41467-021-27944-8","article-title":"HIF-1 Interacts with TRIM28 and DNA-PK to release paused RNA polymerase II and activate target gene transcription in response to hypoxia","volume":"13","author":"Yang","year":"2022","journal-title":"Nat. Commun."},{"key":"10.1016\/j.tim.2024.05.007_bb0210","doi-asserted-by":"crossref","first-page":"3361","DOI":"10.1172\/JCI136225","article-title":"Herpesvirus latency","volume":"130","author":"Cohen","year":"2020","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.tim.2024.05.007_bb0215","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1016\/j.tim.2016.11.009","article-title":"Herpesviruses and their host cells: a successful liaison","volume":"25","author":"Adler","year":"2017","journal-title":"Trends Microbiol."},{"key":"10.1016\/j.tim.2024.05.007_bb0220","doi-asserted-by":"crossref","DOI":"10.1371\/journal.ppat.1009447","article-title":"A heterochromatin inducing protein differentially recognizes self versus foreign genomes","volume":"17","author":"Burton","year":"2021","journal-title":"PLoS Pathog."},{"key":"10.1016\/j.tim.2024.05.007_bb0225","doi-asserted-by":"crossref","first-page":"11347","DOI":"10.1128\/JVI.02008-15","article-title":"STAT3 Regulates lytic activation of Kaposi's sarcoma-associated herpesvirus","volume":"89","author":"King","year":"2015","journal-title":"J. Virol."},{"key":"10.1016\/j.tim.2024.05.007_bb0230","doi-asserted-by":"crossref","DOI":"10.1371\/journal.ppat.1006249","article-title":"Chloroquine triggers Epstein\u2013Barr virus replication through phosphorylation of KAP1\/TRIM28 in Burkitt lymphoma cells","volume":"13","author":"Li","year":"2017","journal-title":"PLoS Pathog."},{"key":"10.1016\/j.tim.2024.05.007_bb0235","doi-asserted-by":"crossref","DOI":"10.1128\/JVI.00298-18","article-title":"KRAB-ZFP repressors enforce quiescence of oncogenic human herpesviruses","volume":"92","author":"Li","year":"2018","journal-title":"J. Virol."},{"key":"10.1016\/j.tim.2024.05.007_bb0240","doi-asserted-by":"crossref","DOI":"10.1128\/JVI.00572-19","article-title":"Retrograde regulation by the viral protein kinase epigenetically sustains the Epstein\u2013Barr virus latency-to-lytic switch to augment virus production","volume":"93","author":"Li","year":"2019","journal-title":"J. Virol."},{"key":"10.1016\/j.tim.2024.05.007_bb0245","doi-asserted-by":"crossref","DOI":"10.1073\/pnas.1316194110","article-title":"Nuclear interferon-inducible protein 16 promotes silencing of herpesviral and transfected DNA","volume":"110","author":"Orzalli","year":"2013","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.tim.2024.05.007_bb0250","doi-asserted-by":"crossref","DOI":"10.7554\/eLife.06068","article-title":"Release of human cytomegalovirus from latency by a KAP1\/TRIM28 phosphorylation switch","volume":"4","author":"Rauwel","year":"2015","journal-title":"Elife"},{"key":"10.1016\/j.tim.2024.05.007_bb0255","doi-asserted-by":"crossref","first-page":"5681","DOI":"10.1158\/0008-5472.CAN-08-4570","article-title":"Kruppel-associated box domain-associated protein-1 as a latency regulator for Kaposi's sarcoma-associated herpesvirus and its modulation by the viral protein kinase","volume":"69","author":"Chang","year":"2009","journal-title":"Cancer Res."},{"key":"10.1016\/j.tim.2024.05.007_bb0260","doi-asserted-by":"crossref","first-page":"7874","DOI":"10.1128\/JVI.00895-15","article-title":"Activated Nrf2 interacts with Kaposi's sarcoma-associated herpesvirus latency protein LANA-1 and host protein KAP1 to mediate global lytic gene repression","volume":"89","author":"Gjyshi","year":"2015","journal-title":"J. Virol."},{"key":"10.1016\/j.tim.2024.05.007_bb0265","doi-asserted-by":"crossref","first-page":"7331","DOI":"10.1128\/JVI.00596-14","article-title":"Kaposi's sarcoma-associated herpesvirus-encoded LANA interacts with host KAP1 to facilitate establishment of viral latency","volume":"88","author":"Sun","year":"2014","journal-title":"J. Virol."},{"key":"10.1016\/j.tim.2024.05.007_bb0270","doi-asserted-by":"crossref","DOI":"10.1371\/journal.ppat.1003750","article-title":"A unique SUMO-2-interacting motif within LANA is essential for KSHV latency","volume":"9","author":"Cai","year":"2013","journal-title":"PLoS Pathog."},{"key":"10.1016\/j.tim.2024.05.007_bb0275","doi-asserted-by":"crossref","DOI":"10.1128\/mBio.01560-18","article-title":"Tumor necrosis factor alpha induces reactivation of human cytomegalovirus independently of myeloid cell differentiation following posttranscriptional establishment of latency","volume":"9","author":"Forte","year":"2018","journal-title":"mBio"},{"key":"10.1016\/j.tim.2024.05.007_bb0280","doi-asserted-by":"crossref","DOI":"10.3389\/fcimb.2022.814307","article-title":"Integrin-linked kinase reduces H3K9 trimethylation to enhance herpes simplex virus 1 replication","volume":"12","author":"Tsai","year":"2022","journal-title":"Front. Cell. Infect. Microbiol."},{"key":"10.1016\/j.tim.2024.05.007_bb0285","doi-asserted-by":"crossref","first-page":"10144","DOI":"10.1128\/JVI.05035-11","article-title":"Epstein\u2013Barr virus latent membrane protein 1 (LMP1) C-terminal-activating region 3 contributes to LMP1-mediated cellular migration via its interaction with Ubc9","volume":"85","author":"Bentz","year":"2011","journal-title":"J. Virol."},{"key":"10.1016\/j.tim.2024.05.007_bb0290","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1038\/s41598-018-36312-4","article-title":"Epstein\u2013Barr virus latent membrane protein-1 induces the expression of SUMO-1 and SUMO-2\/3 in LMP1-positive lymphomas and cells","volume":"9","author":"Salahuddin","year":"2019","journal-title":"Sci. Rep."},{"key":"10.1016\/j.tim.2024.05.007_bb0295","doi-asserted-by":"crossref","first-page":"9523","DOI":"10.1038\/s41598-019-45825-5","article-title":"The Epstein\u2013Barr virus oncoprotein, LMP1, regulates the function of SENP2, a SUMO-protease","volume":"9","author":"Selby","year":"2019","journal-title":"Sci. Rep."},{"key":"10.1016\/j.tim.2024.05.007_bb0300","doi-asserted-by":"crossref","DOI":"10.3389\/fmicb.2022.999290","article-title":"Latency-associated upregulation of SERBP1 is important for the recruitment of transcriptional repressors to the viral major immediate early promoter of human cytomegalovirus during latent carriage","volume":"13","author":"Poole","year":"2022","journal-title":"Front. Microbiol."},{"key":"10.1016\/j.tim.2024.05.007_bb0305","doi-asserted-by":"crossref","DOI":"10.1128\/JVI.00342-18","article-title":"Chromatin-remodeling factor SPOC1 acts as a cellular restriction factor against human cytomegalovirus by repressing the major immediate early promoter","volume":"92","author":"Reichel","year":"2018","journal-title":"J. Virol."},{"key":"10.1016\/j.tim.2024.05.007_bb0310","doi-asserted-by":"crossref","first-page":"2023","DOI":"10.1002\/pmic.201400624","article-title":"Proteomic profiling identifies the SIM-associated complex of KSHV-encoded LANA","volume":"15","author":"Gan","year":"2015","journal-title":"Proteomics"},{"key":"10.1016\/j.tim.2024.05.007_bb0315","doi-asserted-by":"crossref","DOI":"10.1371\/journal.ppat.1008447","article-title":"STUB1 is targeted by the SUMO-interacting motif of EBNA1 to maintain Epstein\u2013Barr virus latency","volume":"16","author":"Wang","year":"2020","journal-title":"PLoS Pathog."},{"key":"10.1016\/j.tim.2024.05.007_bb0320","doi-asserted-by":"crossref","DOI":"10.1093\/femspd\/ftae002","article-title":"Awakening the sleeping giant: Epstein\u2013Barr virus reactivation by biological agents","volume":"82","author":"Indari","year":"2024","journal-title":"Pathog. Dis."},{"key":"10.1016\/j.tim.2024.05.007_bb0325","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1016\/j.jviromet.2006.06.006","article-title":"Cells lytically infected with Epstein\u2013Barr virus are detected and separable by immunoglobulins from EBV-seropositive individuals","volume":"137","author":"Bhaduri-McIntosh","year":"2006","journal-title":"J. Virol. Methods"},{"key":"10.1016\/j.tim.2024.05.007_bb0330","doi-asserted-by":"crossref","first-page":"11438","DOI":"10.1128\/JVI.01762-13","article-title":"Signal transducer and activator of transcription 3 limits Epstein\u2013Barr virus lytic activation in B lymphocytes","volume":"87","author":"Hill","year":"2013","journal-title":"J. Virol."},{"key":"10.1016\/j.tim.2024.05.007_bb0335","doi-asserted-by":"crossref","first-page":"1722","DOI":"10.1073\/pnas.1919133117","article-title":"A promiscuous inflammasome sparks replication of a common tumor virus","volume":"117","author":"Burton","year":"2020","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.tim.2024.05.007_bb0340","doi-asserted-by":"crossref","first-page":"881","DOI":"10.1093\/ndt\/gfx356","article-title":"Incidence and predictors of post-transplant lymphoproliferative disease after kidney transplantation during adulthood and childhood: a registry study","volume":"33","author":"Francis","year":"2018","journal-title":"Nephrol. Dial. Transplant."},{"key":"10.1016\/j.tim.2024.05.007_bb0345","doi-asserted-by":"crossref","first-page":"2606","DOI":"10.1080\/21645515.2017.1368600","article-title":"Risk and impact of herpes zoster on patients with diabetes: a population-based study, 2009-2014","volume":"13","author":"Munoz-Quiles","year":"2017","journal-title":"Hum. Vaccin. Immunother."},{"key":"10.1016\/j.tim.2024.05.007_bb0350","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1007\/s13300-018-0394-4","article-title":"Herpes zoster and diabetes mellitus: a review","volume":"9","author":"Papagianni","year":"2018","journal-title":"Diabetes Ther."},{"key":"10.1016\/j.tim.2024.05.007_bb0355","series-title":"Fields Virology","first-page":"2480","article-title":"The Family of Herpesviridae: a Brief Introduction","author":"Pellett","year":"2007"},{"key":"10.1016\/j.tim.2024.05.007_bb0360","doi-asserted-by":"crossref","first-page":"11104","DOI":"10.1093\/nar\/gkad823","article-title":"ATM, KAP1 and the Epstein\u2013Barr virus polymerase processivity factor direct traffic at the intersection of transcription and replication","volume":"51","author":"Xu","year":"2023","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.tim.2024.05.007_bb0365","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1038\/s41571-023-00736-3","article-title":"Protein degraders enter the clinic - a new approach to cancer therapy","volume":"20","author":"Chirnomas","year":"2023","journal-title":"Nat. Rev. Clin. Oncol."}],"container-title":["Trends in Microbiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0966842X24001380?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0966842X24001380?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,12,3]],"date-time":"2024-12-03T11:38:56Z","timestamp":1733225936000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0966842X24001380"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,12]]},"references-count":73,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2024,12]]}},"alternative-id":["S0966842X24001380"],"URL":"https:\/\/doi.org\/10.1016\/j.tim.2024.05.007","relation":{},"ISSN":["0966-842X"],"issn-type":[{"value":"0966-842X","type":"print"}],"subject":[],"published":{"date-parts":[[2024,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"KAP1\/TRIM28 \u2013 antiviral and proviral protagonist of herpesvirus biology","name":"articletitle","label":"Article Title"},{"value":"Trends in Microbiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.tim.2024.05.007","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Elsevier Ltd. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}