{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,26]],"date-time":"2026-10-26T03:24:43Z","timestamp":1792985083415,"version":"4.5.0"},"reference-count":102,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/100008069","name":"University of California, San Francisco","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100008069","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000026","name":"National Institute on Drug Abuse","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000026","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000738","name":"U.S. Department of Veterans Affairs","doi-asserted-by":"publisher","award":["I01CX001065"],"award-info":[{"award-number":["I01CX001065"]}],"id":[{"id":"10.13039\/100000738","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["RO1-NS72211"],"award-info":[{"award-number":["RO1-NS72211"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R21-AT009034"],"award-info":[{"award-number":["R21-AT009034"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["K08-AT009385"],"award-info":[{"award-number":["K08-AT009385"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R35-HL135779"],"award-info":[{"award-number":["R35-HL135779"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["ZIA-AA000218"],"award-info":[{"award-number":["ZIA-AA000218"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R33-AT009932"],"award-info":[{"award-number":["R33-AT009932"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R21-DK116029"],"award-info":[{"award-number":["R21-DK116029"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["P01-AT009965"],"award-info":[{"award-number":["P01-AT009965"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R01-AT10742"],"award-info":[{"award-number":["R01-AT10742"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R01-HL135183"],"award-info":[{"award-number":["R01-HL135183"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R21-MH103468"],"award-info":[{"award-number":["R21-MH103468"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["OT2-OD023867"],"award-info":[{"award-number":["OT2-OD023867"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["ZIA-DA000635"],"award-info":[{"award-number":["ZIA-DA000635"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["cell.com","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Trends in Neurosciences"],"published-print":{"date-parts":[[2021,1]]},"DOI":"10.1016\/j.tins.2020.09.010","type":"journal-article","created":{"date-parts":[[2020,12,29]],"date-time":"2020-12-29T17:00:59Z","timestamp":1609261259000},"page":"52-62","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":234,"title":["Interventions and Manipulations of Interoception"],"prefix":"10.1016","volume":"44","author":[{"given":"Helen Y.","family":"Weng","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jack L.","family":"Feldman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lorenzo","family":"Leggio","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vitaly","family":"Napadow","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeanie","family":"Park","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cynthia J.","family":"Price","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.tins.2020.09.010_bb0005","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/j.tins.2020.10.007","article-title":"The emerging science of interoception: sensing, integrating, interpreting, and regulating signals within the self","volume":"44","author":"Chen","year":"2021","journal-title":"Trends Neurosci."},{"key":"10.1016\/j.tins.2020.09.010_bb0010","first-page":"501","article-title":"Interoception and mental health: a roadmap","volume":"3","author":"Khalsa","year":"2017","journal-title":"Biol. Psychiatry Cogn. Neurosci. Neuroimaging"},{"key":"10.1016\/j.tins.2020.09.010_bb0015","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/j.tins.2020.09.011","article-title":"Neural circuits of interoception.","volume":"44","author":"Berntson","year":"2021","journal-title":"Trends Neurosci."},{"key":"10.1016\/j.tins.2020.09.010_bb0020","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/j.tins.2020.09.009","article-title":"Diseases, disorders, and comorbidities of interoception","volume":"44","author":"Bonaz","year":"2021","journal-title":"Trends Neurosci."},{"key":"10.1016\/j.tins.2020.09.010_bb0025","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1016\/j.tins.2020.09.012","article-title":"Computational models of interoception and body regulation.","volume":"44","author":"Petzschner","year":"2021","journal-title":"Trends Neurosci."},{"key":"10.1016\/j.tins.2020.09.010_bb0030","doi-asserted-by":"crossref","first-page":"1011","DOI":"10.1113\/expphysiol.2008.042424","article-title":"Breathing rhythms and emotions","volume":"93","author":"Homma","year":"2008","journal-title":"Exp. Physiol."},{"key":"10.1016\/j.tins.2020.09.010_bb0035","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1016\/j.concog.2017.09.008","article-title":"Rhythms of the body, rhythms of the brain: respiration, neural oscillations, and embodied cognition","volume":"56","author":"Varga","year":"2017","journal-title":"Conscious. Cogn."},{"key":"10.1016\/j.tins.2020.09.010_bb0040","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1038\/s41583-018-0003-6","article-title":"Breathing matters","volume":"19","author":"Del Negro","year":"2018","journal-title":"Nat. Rev. Neurosci."},{"key":"10.1016\/j.tins.2020.09.010_bb0045","article-title":"Breathing coordinates limbic network dynamics underlying memory consolidation","author":"Karalis","year":"2018","journal-title":"bioRxiv"},{"key":"10.1016\/j.tins.2020.09.010_bb0050","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1016\/j.tins.2018.01.007","article-title":"Respiration-entrained brain rhythms are global but often overlooked","volume":"41","author":"Tort","year":"2018","journal-title":"Trends Neurosci."},{"key":"10.1016\/j.tins.2020.09.010_bb0055","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1016\/j.resp.2008.07.011","article-title":"Panic disorder and control of breathing","volume":"167","author":"Nardi","year":"2009","journal-title":"Respir. Physiol. Neurobiol."},{"key":"10.1016\/j.tins.2020.09.010_bb0060","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1007\/s12671-010-0012-7","article-title":"Mindfulness for psychologists: paying kind attention to the perceptible","volume":"1","author":"Grossman","year":"2010","journal-title":"Mindfulness"},{"key":"10.1016\/j.tins.2020.09.010_bb0065","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/S0079-6123(08)63799-1","article-title":"Afferent regulation of locus coeruleus neurons: anatomy, physiology and pharmacology","volume":"88","author":"Aston-Jones","year":"1991","journal-title":"Prog. Brain Res."},{"key":"10.1016\/j.tins.2020.09.010_bb0070","doi-asserted-by":"crossref","first-page":"410","DOI":"10.1002\/(SICI)1096-9861(19990927)412:3<410::AID-CNE3>3.0.CO;2-F","article-title":"Efferent projections of the nucleus of the solitary tract to peri-locus coeruleus dendrites in rat brain: evidence for a monosynaptic pathway","volume":"412","author":"Bockstaele","year":"1999","journal-title":"J. Comp. Neurol."},{"key":"10.1016\/j.tins.2020.09.010_bb0075","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1111\/head.12650","article-title":"Vagus nerve and vagus nerve stimulation, a comprehensive review: part II","volume":"56","author":"Yuan","year":"2016","journal-title":"Headache"},{"key":"10.1016\/j.tins.2020.09.010_bb0080","first-page":"57","article-title":"Vagus nerve stimulation in patients with migraine","volume":"57","author":"Mosqueira","year":"2013","journal-title":"Rev. Neurol."},{"key":"10.1016\/j.tins.2020.09.010_bb0085","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1016\/0006-8993(84)90756-X","article-title":"Central distribution of primary afferent fibers in the Arnold\u2019s nerve (the auricular branch of the vagus nerve): a transganglionic HRP study in the cat","volume":"292","author":"Nomura","year":"1984","journal-title":"Brain Res."},{"key":"10.1016\/j.tins.2020.09.010_bb0090","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1007\/s12565-014-0231-4","article-title":"Origin, course and distribution of the nerves to the posterosuperior wall of the external acoustic meatus","volume":"89","author":"Kiyokawa","year":"2014","journal-title":"Anat. Sci. Int."},{"key":"10.1016\/j.tins.2020.09.010_bb0095","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1002\/ca.1089","article-title":"The nerve supply of the human auricle","volume":"15","author":"Peuker","year":"2002","journal-title":"Clin. Anat."},{"key":"10.1016\/j.tins.2020.09.010_bb0100","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1007\/s003810050021","article-title":"Transcutaneous vagus nerve stimulation for partial onset seizure therapy. A new concept","volume":"16","author":"Ventureyra","year":"2000","journal-title":"Childs Nerv. Syst."},{"key":"10.1016\/j.tins.2020.09.010_bb0105","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1111\/head.12647","article-title":"Vagus nerve and vagus nerve stimulation, a comprehensive review: part I","volume":"56","author":"Yuan","year":"2016","journal-title":"Headache"},{"key":"10.1016\/j.tins.2020.09.010_bb0110","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1515\/BMT.2008.022","article-title":"A novel transcutaneous vagus nerve stimulation leads to brainstem and cerebral activations measured by functional MRI","volume":"53","author":"Dietrich","year":"2008","journal-title":"Biomed. Tech. (Berl.)"},{"key":"10.1016\/j.tins.2020.09.010_bb0115","doi-asserted-by":"crossref","first-page":"798","DOI":"10.1016\/j.brs.2013.01.011","article-title":"CNS BOLD fMRI effects of sham-controlled transcutaneous electrical nerve stimulation in the left outer auditory canal \u2013 a pilot study","volume":"6","author":"Kraus","year":"2013","journal-title":"Brain Stimulat."},{"key":"10.1016\/j.tins.2020.09.010_bb0120","doi-asserted-by":"crossref","first-page":"624","DOI":"10.1016\/j.brs.2014.11.018","article-title":"Non-invasive access to the vagus nerve central projections via electrical stimulation of the external ear: fMRI evidence in humans","volume":"8","author":"Frangos","year":"2015","journal-title":"Brain Stimulat."},{"key":"10.1016\/j.tins.2020.09.010_bb0125","doi-asserted-by":"crossref","first-page":"1461","DOI":"10.1097\/j.pain.0000000000000930","article-title":"Modulation of brainstem activity and connectivity by respiratory-gated auricular vagal afferent nerve stimulation in migraine patients","volume":"158","author":"Garcia","year":"2017","journal-title":"Pain"},{"key":"10.1016\/j.tins.2020.09.010_bb0130","doi-asserted-by":"crossref","first-page":"911","DOI":"10.1016\/j.brs.2019.02.003","article-title":"The influence of respiration on brainstem and cardiovagal response to auricular vagus nerve stimulation: a multimodal ultrahigh-field (7T) fMRI study","volume":"12","author":"Sclocco","year":"2019","journal-title":"Brain Stimulat."},{"key":"10.1016\/j.tins.2020.09.010_bb0135","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1016\/S0304-3940(98)00402-9","article-title":"Activity of rat pump neurons is modulated with central respiratory rhythm","volume":"249","author":"Miyazaki","year":"1998","journal-title":"Neurosci. Lett."},{"key":"10.1016\/j.tins.2020.09.010_bb0140","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1007\/s002210050889","article-title":"Excitatory and inhibitory synaptic inputs shape the discharge pattern of pump neurons of the nucleus tractus solitarii in the rat","volume":"129","author":"Miyazaki","year":"1999","journal-title":"Exp. Brain Res."},{"key":"10.1016\/j.tins.2020.09.010_bb0145","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1016\/j.resp.2010.09.006","article-title":"Effect of baroreceptor stimulation on the respiratory pattern: insights into respiratory\u2013sympathetic interactions","volume":"174","author":"Baekey","year":"2010","journal-title":"Respir. Physiol. Neurobiol."},{"key":"10.1016\/j.tins.2020.09.010_bb0150","doi-asserted-by":"crossref","first-page":"777","DOI":"10.1111\/j.1526-4637.2012.01385.x","article-title":"Evoked pain analgesia in chronic pelvic pain patients using respiratory-gated auricular vagal afferent nerve stimulation","volume":"13","author":"Napadow","year":"2012","journal-title":"Pain Med."},{"key":"10.1016\/j.tins.2020.09.010_bb0155","doi-asserted-by":"crossref","first-page":"12448","DOI":"10.1523\/JNEUROSCI.2586-16.2016","article-title":"Nasal respiration entrains human limbic oscillations and modulates cognitive function","volume":"36","author":"Zelano","year":"2016","journal-title":"J. Neurosci."},{"key":"10.1016\/j.tins.2020.09.010_bb0160","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1038\/nrn2555","article-title":"How do you feel \u2013 now? The anterior insula and human awareness","volume":"10","author":"Craig","year":"2009","journal-title":"Nat. Rev. Neurosci."},{"key":"10.1016\/j.tins.2020.09.010_bb0165","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1146\/annurev.psych.093008.100427","article-title":"A taxonomy of external and internal attention","volume":"62","author":"Chun","year":"2011","journal-title":"Annu. Rev. Psychol."},{"key":"10.1016\/j.tins.2020.09.010_bb0170","doi-asserted-by":"crossref","first-page":"1536","DOI":"10.1016\/j.neuroimage.2006.02.048","article-title":"Separating respiratory-variation-related fluctuations from neuronal-activity-related fluctuations in fMRI","volume":"31","author":"Birn","year":"2006","journal-title":"Neuroimage"},{"key":"10.1016\/j.tins.2020.09.010_bb0175","doi-asserted-by":"crossref","first-page":"644","DOI":"10.1016\/j.neuroimage.2007.11.059","article-title":"The respiration response function: the temporal dynamics of fMRI signal fluctuations related to changes in respiration","volume":"40","author":"Birn","year":"2008","journal-title":"Neuroimage"},{"key":"10.1016\/j.tins.2020.09.010_bb0180","series-title":"Full Catastrophe Living: Using the Wisdom of Your Body and Mind to Face Stress, Pain, and Illness","author":"Kabat-Zinn","year":"2007"},{"key":"10.1016\/j.tins.2020.09.010_bb0185","doi-asserted-by":"crossref","first-page":"763","DOI":"10.3389\/fpsyg.2015.00763","article-title":"Interoception, contemplative practice, and health","volume":"6","author":"Farb","year":"2015","journal-title":"Front. Psychol."},{"key":"10.1016\/j.tins.2020.09.010_bb0190","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1016\/j.tics.2008.01.005","article-title":"Attention regulation and monitoring in meditation","volume":"12","author":"Lutz","year":"2008","journal-title":"Trends Cogn. Sci."},{"key":"10.1016\/j.tins.2020.09.010_bb0195","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1038\/nrn3916","article-title":"The neuroscience of mindfulness meditation","volume":"16","author":"Tang","year":"2015","journal-title":"Nat. Rev. Neurosci."},{"key":"10.1016\/j.tins.2020.09.010_bb0200","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1016\/j.tics.2015.07.001","article-title":"Reconstructing and deconstructing the self: cognitive mechanisms in meditation practice","volume":"19","author":"Dahl","year":"2015","journal-title":"Trends Cogn. Sci."},{"key":"10.1016\/j.tins.2020.09.010_bb0205","doi-asserted-by":"crossref","first-page":"560","DOI":"10.1016\/j.cpr.2009.06.005","article-title":"Mindful emotion regulation: an integrative review","volume":"29","author":"Chambers","year":"2009","journal-title":"Clin. Psychol. Rev."},{"key":"10.1016\/j.tins.2020.09.010_bb0210","doi-asserted-by":"crossref","first-page":"356","DOI":"10.1007\/s12671-013-0269-8","article-title":"Moving beyond mindfulness: defining equanimity as an outcome measure in meditation and contemplative research","volume":"6","author":"Desbordes","year":"2015","journal-title":"Mindfulness"},{"key":"10.1016\/j.tins.2020.09.010_bb0215","doi-asserted-by":"crossref","first-page":"1171","DOI":"10.1177\/0956797612469537","article-title":"Compassion training alters altruism and neural responses to suffering","volume":"24","author":"Weng","year":"2013","journal-title":"Psychol. Sci."},{"key":"10.1016\/j.tins.2020.09.010_bb0220","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1177\/2167702618812438","article-title":"Soothing your heart and feeling connected: a new experimental paradigm to study the benefits of self-compassion","volume":"7","author":"Kirschner","year":"2019","journal-title":"Clin. Psychol. Sci."},{"key":"10.1016\/j.tins.2020.09.010_bb0225","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/j.tins.2020.09.008","article-title":"Functions of interoception: from energy regulation to experience of the self.","volume":"44","author":"Quigley","year":"2021","journal-title":"Trends Neurosci."},{"key":"10.1016\/j.tins.2020.09.010_bb0230","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1093\/clipsy.bpg015","article-title":"Mindfulness training as a clinical intervention: a conceptual and empirical review","volume":"10","author":"Baer","year":"2003","journal-title":"Clin. Psychol. Sci. Pract."},{"key":"10.1016\/j.tins.2020.09.010_bb0235","doi-asserted-by":"crossref","first-page":"15307","DOI":"10.1523\/JNEUROSCI.2542-15.2015","article-title":"Mindfulness meditation-based pain relief employs different neural mechanisms than placebo and sham mindfulness meditation-induced analgesia","volume":"35","author":"Zeidan","year":"2015","journal-title":"J. Neurosci."},{"key":"10.1016\/j.tins.2020.09.010_bb0240","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1037\/0022-006X.72.1.31","article-title":"Mindfulness-based cognitive therapy for depression: replication and exploration of differential relapse prevention effects","volume":"72","author":"Ma","year":"2004","journal-title":"J. Consult. Clin. Psychol."},{"key":"10.1016\/j.tins.2020.09.010_bb0245","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1037\/a0029258","article-title":"Retraining the addicted brain: a review of hypothesized neurobiological mechanisms of mindfulness-based relapse prevention","volume":"27","author":"Witkiewitz","year":"2013","journal-title":"Psychol. Addict. Behav."},{"key":"10.1016\/j.tins.2020.09.010_bb0250","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1038\/nrn755","article-title":"Control of goal-directed and stimulus-driven attention in the brain","volume":"3","author":"Corbetta","year":"2002","journal-title":"Nat. Rev. Neurosci."},{"key":"10.1016\/j.tins.2020.09.010_bb0255","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1146\/annurev-neuro-062111-150525","article-title":"The attention system of the human brain: 20 years after","volume":"35","author":"Petersen","year":"2012","journal-title":"Annu. Rev. Neurosci."},{"key":"10.1016\/j.tins.2020.09.010_bb0260","doi-asserted-by":"crossref","first-page":"11073","DOI":"10.1073\/pnas.0704320104","article-title":"Distinct brain networks for adaptive and stable task control in humans","volume":"104","author":"Dosenbach","year":"2007","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.tins.2020.09.010_bb0265","doi-asserted-by":"crossref","first-page":"655","DOI":"10.1007\/s00429-010-0262-0","article-title":"Saliency, switching, attention and control: a network model of insula function","volume":"214","author":"Menon","year":"2010","journal-title":"Brain Struct. Funct."},{"key":"10.1016\/j.tins.2020.09.010_bb0270","doi-asserted-by":"crossref","first-page":"2944","DOI":"10.1002\/hbm.22113","article-title":"Keeping the body in mind: insula functional organization and functional connectivity integrate interoceptive, exteroceptive, and emotional awareness","volume":"34","author":"Simmons","year":"2013","journal-title":"Hum. Brain Mapp."},{"key":"10.1016\/j.tins.2020.09.010_bb0275","doi-asserted-by":"crossref","first-page":"11483","DOI":"10.1073\/pnas.0606552104","article-title":"Neural correlates of attentional expertise in long-term meditation practitioners","volume":"104","author":"Brefczynski-Lewis","year":"2007","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.tins.2020.09.010_bb0280","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1016\/j.neubiorev.2016.03.021","article-title":"Functional neuroanatomy of meditation: a review and meta-analysis of 78 functional neuroimaging investigations","volume":"65","author":"Fox","year":"2016","journal-title":"Neurosci. Biobehav. Rev."},{"key":"10.1016\/j.tins.2020.09.010_bb0285","doi-asserted-by":"crossref","first-page":"294","DOI":"10.1016\/j.copsyc.2019.04.004","article-title":"Frontal theta activity and white matter plasticity following mindfulness meditation","volume":"28","author":"Tang","year":"2019","journal-title":"Curr. Opin. Psychol."},{"key":"10.1016\/j.tins.2020.09.010_bb0290","doi-asserted-by":"crossref","first-page":"414","DOI":"10.1016\/j.tics.2014.04.012","article-title":"Frontal theta as a mechanism for cognitive control","volume":"18","author":"Cavanagh","year":"2014","journal-title":"Trends Cogn. Sci."},{"key":"10.1016\/j.tins.2020.09.010_bb0295","doi-asserted-by":"crossref","first-page":"E6339","DOI":"10.1073\/pnas.1802160115","article-title":"Changes in white matter in mice resulting from low-frequency brain stimulation","volume":"115","author":"Piscopo","year":"2018","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.tins.2020.09.010_bb0300","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1093\/scan\/nss066","article-title":"Mindfulness meditation training alters cortical representations of interoceptive attention","volume":"8","author":"Farb","year":"2013","journal-title":"Soc. Cogn. Affect. Neurosci."},{"key":"10.1016\/j.tins.2020.09.010_bb0305","doi-asserted-by":"crossref","first-page":"20254","DOI":"10.1073\/pnas.1112029108","article-title":"Meditation experience is associated with differences in default mode network activity and connectivity","volume":"108","author":"Brewer","year":"2011","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.tins.2020.09.010_bb0310","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1111\/nyas.12360","article-title":"The default network and self-generated thought: component processes, dynamic control, and clinical relevance","volume":"1316","author":"Andrews-Hanna","year":"2014","journal-title":"Ann. N. Y. Acad. Sci."},{"key":"10.1016\/j.tins.2020.09.010_bb0315","doi-asserted-by":"crossref","first-page":"366","DOI":"10.3389\/fnhum.2020.00336","article-title":"Focus on the breath: brain decoding reveals internal states of attention during meditation","volume":"14","author":"Weng","year":"2020","journal-title":"Front. Hum. Neurosci."},{"key":"10.1016\/j.tins.2020.09.010_bb0320","doi-asserted-by":"crossref","first-page":"356","DOI":"10.1016\/j.neuroimage.2015.02.026","article-title":"Functional subdivision of the human periaqueductal grey in respiratory control using 7tesla fMRI","volume":"113","author":"Faull","year":"2015","journal-title":"Neuroimage"},{"key":"10.1016\/j.tins.2020.09.010_bb0325","doi-asserted-by":"crossref","first-page":"846","DOI":"10.1161\/HYPERTENSIONAHA.110.164780","article-title":"Early sympathetic activation in the initial clinical stages of chronic renal failure","volume":"57","author":"Grassi","year":"2011","journal-title":"Hypertension"},{"key":"10.1016\/j.tins.2020.09.010_bb0330","doi-asserted-by":"crossref","first-page":"4893","DOI":"10.1113\/JP274269","article-title":"Baroreflex dysfunction and augmented sympathetic nerve responses during mental stress in veterans with post-traumatic stress disorder","volume":"595","author":"Park","year":"2017","journal-title":"J. Physiol."},{"key":"10.1016\/j.tins.2020.09.010_bb0335","doi-asserted-by":"crossref","first-page":"II30","DOI":"10.1161\/01.HYP.11.3_Pt_2.II30","article-title":"Side effects of sympatholytic antihypertensive drugs","volume":"11","author":"Engelman","year":"1988","journal-title":"Hypertension"},{"key":"10.1016\/j.tins.2020.09.010_bb0340","doi-asserted-by":"crossref","first-page":"215","DOI":"10.2174\/157339910791658844","article-title":"Antihypertensive treatment with \u03b2-blockers in the metabolic syndrome: a review","volume":"6","author":"Carella","year":"2010","journal-title":"Curr. Diabetes Rev."},{"key":"10.1016\/j.tins.2020.09.010_bb0345","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1161\/01.RES.67.1.130","article-title":"Influence of lung volume on sympathetic nerve discharge in normal humans","volume":"67","author":"Seals","year":"1990","journal-title":"Circ. Res."},{"key":"10.1016\/j.tins.2020.09.010_bb0350","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1161\/hc0202.103311","article-title":"Slow breathing increases arterial baroreflex sensitivity in patients with chronic heart failure","volume":"105","author":"Bernardi","year":"2002","journal-title":"Circulation"},{"key":"10.1016\/j.tins.2020.09.010_bb0355","doi-asserted-by":"crossref","first-page":"714","DOI":"10.1161\/01.HYP.0000179581.68566.7d","article-title":"Slow breathing improves arterial baroreflex sensitivity and decreases blood pressure in essential hypertension","volume":"46","author":"Joseph","year":"2005","journal-title":"Hypertension"},{"key":"10.1016\/j.tins.2020.09.010_bb0360","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1097\/CRD.0b013e3181fc1ae6","article-title":"RESPeRATE: nonpharmacological treatment of hypertension","volume":"19","author":"Sharma","year":"2011","journal-title":"Cardiol. Rev."},{"key":"10.1016\/j.tins.2020.09.010_bb0365","doi-asserted-by":"crossref","first-page":"806","DOI":"10.1016\/j.ahj.2013.07.031","article-title":"Posttraumatic stress disorder and risk for coronary heart disease: a meta-analytic review","volume":"166","author":"Edmondson","year":"2013","journal-title":"Am. Heart J."},{"key":"10.1016\/j.tins.2020.09.010_bb0370","doi-asserted-by":"crossref","first-page":"1026","DOI":"10.1161\/HYPERTENSIONAHA.109.146621","article-title":"Greater cardiovascular responses to laboratory mental stress are associated with poor subsequent cardiovascular risk status: a meta-analysis of prospective evidence","volume":"55","author":"Chida","year":"2010","journal-title":"Hypertension"},{"key":"10.1016\/j.tins.2020.09.010_bb0375","doi-asserted-by":"crossref","first-page":"H141","DOI":"10.1152\/ajpheart.00098.2018","article-title":"Acute effects of device-guided slow breathing on sympathetic nerve activity and baroreflex sensitivity in posttraumatic stress disorder","volume":"315","author":"Fonkoue","year":"2018","journal-title":"Am. J. Physiol. Heart Circ. Physiol."},{"key":"10.1016\/j.tins.2020.09.010_bb0380","doi-asserted-by":"crossref","first-page":"R466","DOI":"10.1152\/ajpregu.00079.2020","article-title":"Eight weeks of device-guided slow breathing decreases sympathetic nervous reactivity to stress in post-traumatic stress disorder","volume":"319","author":"Fonkoue","year":"2020","journal-title":"Am. J. Physiol. Regul. Integr. Comp. Physiol."},{"key":"10.1016\/j.tins.2020.09.010_bb0385","doi-asserted-by":"crossref","first-page":"2984","DOI":"10.1210\/jc.2012-3742","article-title":"PTSD symptom reduction with mindfulness-based stretching and deep breathing exercise: randomized controlled clinical trial of efficacy","volume":"98","author":"Kim","year":"2013","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"10.1016\/j.tins.2020.09.010_bb0390","doi-asserted-by":"crossref","first-page":"R93","DOI":"10.1152\/ajpregu.00558.2013","article-title":"Mindfulness meditation lowers muscle sympathetic nerve activity and blood pressure in African-American males with chronic kidney disease","volume":"307","author":"Park","year":"2014","journal-title":"Am. J. Physiol. Regul. Integr. Comp. Physiol."},{"key":"10.1016\/j.tins.2020.09.010_bb0395","doi-asserted-by":"crossref","DOI":"10.1038\/srep27533","article-title":"Long-term mindfulness training is associated with reliable differences in resting respiration rate","volume":"6","author":"Wielgosz","year":"2016","journal-title":"Sci. Rep."},{"key":"10.1016\/j.tins.2020.09.010_bb0400","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1037\/0033-2909.109.1.25","article-title":"Beyond attentional strategies: a cognitive-perceptual model of somatic interpretation","volume":"109","author":"Cioffi","year":"1991","journal-title":"Psychol. Bull."},{"key":"10.1016\/j.tins.2020.09.010_bb0405","doi-asserted-by":"crossref","first-page":"798","DOI":"10.3389\/fpsyg.2018.00798","article-title":"Interoceptive awareness skills for emotion regulation: theory and approach of Mindful Awareness in Body-oriented Therapy (MABT)","volume":"9","author":"Price","year":"2018","journal-title":"Front. Psychol."},{"key":"10.1016\/j.tins.2020.09.010_bb0410","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1016\/j.jsat.2011.09.016","article-title":"Mindful Awareness in Body-oriented Therapy as an adjunct to women\u2019s substance use disorder treatment: a pilot feasibility study","volume":"43","author":"Price","year":"2012","journal-title":"J. Subst. Abus. Treat."},{"key":"10.1016\/j.tins.2020.09.010_bb0415","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1016\/j.drugalcdep.2019.02.012","article-title":"Longitudinal effects of interoceptive awareness training through mindful awareness in body-oriented therapy (MABT) as an adjunct to women\u2019s substance use disorder treatment: a randomized controlled trial","volume":"198","author":"Price","year":"2019","journal-title":"Drug Alcohol Depend."},{"key":"10.1016\/j.tins.2020.09.010_bb0420","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1080\/08897077.2018.1488335","article-title":"Immediate effects of interoceptive awareness training through Mindful Awareness in Body-oriented Therapy (MABT) for women in substance use disorder treatment","volume":"40","author":"Price","year":"2019","journal-title":"Subst. Abus."},{"key":"10.1016\/j.tins.2020.09.010_bb0425","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1017\/S0954579401002012","article-title":"Vagal tone, development, and Gray\u2019s motivational theory: toward an integrated model of autonomic nervous system functioning in psychopathology","volume":"13","author":"Beauchaine","year":"2001","journal-title":"Dev. Psychopathol."},{"key":"10.1016\/j.tins.2020.09.010_bb0430","doi-asserted-by":"crossref","first-page":"1107","DOI":"10.1037\/0022-3514.73.5.1107","article-title":"Regulatory control and adults\u2019 stress-related responses to daily life events","volume":"73","author":"Fabes","year":"1997","journal-title":"J. Pers. Soc. Psychol."},{"key":"10.1016\/j.tins.2020.09.010_bb0435","doi-asserted-by":"crossref","first-page":"565","DOI":"10.1016\/j.tics.2013.09.007","article-title":"Interoceptive inference, emotion, and the embodied self","volume":"17","author":"Seth","year":"2013","journal-title":"Trends Cogn. Sci."},{"key":"10.1016\/j.tins.2020.09.010_bb0440","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1016\/j.tics.2014.02.001","article-title":"Interoceptive inference: homeostasis and decision-making","volume":"18","author":"Gu","year":"2014","journal-title":"Trends Cogn. Sci."},{"key":"10.1016\/j.tins.2020.09.010_bb0445","doi-asserted-by":"crossref","first-page":"1857","DOI":"10.1016\/j.neubiorev.2012.05.007","article-title":"The role of interoception in addiction: a critical review","volume":"36","author":"Verdejo-Garcia","year":"2012","journal-title":"Neurosci. Biobehav. Rev."},{"key":"10.1016\/j.tins.2020.09.010_bb0450","doi-asserted-by":"crossref","first-page":"342","DOI":"10.1016\/j.neuropharm.2013.07.002","article-title":"Interoception and drug addiction","volume":"76","author":"Paulus","year":"2014","journal-title":"Neuropharmacology"},{"key":"10.1016\/j.tins.2020.09.010_bb0455","doi-asserted-by":"crossref","first-page":"1375","DOI":"10.1038\/npp.2016.269","article-title":"Pathological overeating: emerging evidence for a compulsivity construct","volume":"42","author":"Moore","year":"2017","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.tins.2020.09.010_bb0460","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1111\/j.1530-0277.2010.01334.x","article-title":"Role of feeding-related pathways in alcohol dependence: a focus on sweet preference, NPY, and ghrelin","volume":"35","author":"Leggio","year":"2011","journal-title":"Alcohol. Clin. Exp. Res."},{"key":"10.1016\/j.tins.2020.09.010_bb0465","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1016\/bs.irn.2017.08.002","article-title":"The role of the ghrelin system in drug addiction","volume":"136","author":"Zallar","year":"2017","journal-title":"Int. Rev. Neurobiol."},{"key":"10.1016\/j.tins.2020.09.010_bb4000","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1016\/j.physbeh.2019.02.008","article-title":"Ghrelin: From a gut hormone to a potential therapeutic target for alcohol use disorder","volume":"204","author":"Farokhnia","year":"2019","journal-title":"Physiol. Behav."},{"key":"10.1016\/j.tins.2020.09.010_bb0475","doi-asserted-by":"crossref","DOI":"10.1111\/acer.13781","article-title":"Stress, motivation, and the gut\u2013brain axis: a focus on the ghrelin system and alcohol use disorder","author":"Morris","year":"2018","journal-title":"Alcohol. Clin. Exp. Res."},{"key":"10.1016\/j.tins.2020.09.010_bb0480","doi-asserted-by":"crossref","first-page":"734","DOI":"10.1016\/j.biopsych.2014.03.019","article-title":"Intravenous ghrelin administration increases alcohol craving in alcohol-dependent heavy drinkers: a preliminary investigation","volume":"76","author":"Leggio","year":"2014","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.tins.2020.09.010_bb0485","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1038\/s41380-018-0064-y","article-title":"The novel ghrelin receptor inverse agonist PF-5190457 administered with alcohol: preclinical safety experiments and a Phase 1b human laboratory study","volume":"25","author":"Lee","year":"2018","journal-title":"Mol. Psychiatry"},{"key":"10.1016\/j.tins.2020.09.010_bb0490","doi-asserted-by":"crossref","first-page":"576","DOI":"10.1177\/014572179902500410","article-title":"Self-awareness in diabetes: using body cues, circumstances, and strategies","volume":"25","author":"Hernandez","year":"1999","journal-title":"Diabetes Educ."},{"key":"10.1016\/j.tins.2020.09.010_bb0495","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1080\/15294145.2017.1294031","article-title":"Mentalizing homeostasis: the social origins of interoceptive inference","volume":"19","author":"Fotopoulou","year":"2017","journal-title":"Neuropsychoanalysis"},{"key":"10.1016\/j.tins.2020.09.010_bb0500","doi-asserted-by":"crossref","first-page":"720","DOI":"10.1037\/fam0000115","article-title":"Physiological linkage in couples and its implications for individual and interpersonal functioning: a literature review","volume":"29","author":"Timmons","year":"2015","journal-title":"J. Fam. Psychol."},{"key":"10.1016\/j.tins.2020.09.010_bb0505","doi-asserted-by":"crossref","first-page":"1796","DOI":"10.1177\/0956797617722551","article-title":"Contagious anxiety: anxious European Americans can transmit their physiological reactivity to African Americans","volume":"28","author":"West","year":"2017","journal-title":"Psychol. Sci."},{"key":"10.1016\/j.tins.2020.09.010_bb0470","doi-asserted-by":"crossref","first-page":"2029","DOI":"10.1038\/mp.2017.226","article-title":"Exogenous ghrelin administration increases alcohol self-administration and modulates brain functional activity in heavy-drinking alcohol-dependent individuals","volume":"23","author":"Farokhnia","year":"2018","journal-title":"Mol. Psychiatry"}],"container-title":["Trends in Neurosciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0166223620302186?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0166223620302186?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,5,13]],"date-time":"2026-05-13T11:21:06Z","timestamp":1778671266000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0166223620302186"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,1]]},"references-count":102,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2021,1]]}},"alternative-id":["S0166223620302186"],"URL":"https:\/\/doi.org\/10.1016\/j.tins.2020.09.010","relation":{},"ISSN":["0166-2236"],"issn-type":[{"value":"0166-2236","type":"print"}],"subject":[],"published":{"date-parts":[[2021,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Interventions and Manipulations of Interoception","name":"articletitle","label":"Article Title"},{"value":"Trends in Neurosciences","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.tins.2020.09.010","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}