{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,17]],"date-time":"2026-07-17T08:05:43Z","timestamp":1784275543656,"version":"3.55.0"},"reference-count":35,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,3,19]],"date-time":"2026-03-19T00:00:00Z","timestamp":1773878400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100004152","name":"Spine Education and Research Institute","doi-asserted-by":"publisher","award":["22 00058"],"award-info":[{"award-number":["22 00058"]}],"id":[{"id":"10.13039\/100004152","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100004152","name":"Spine Education and Research Institute","doi-asserted-by":"publisher","award":["10061955"],"award-info":[{"award-number":["10061955"]}],"id":[{"id":"10.13039\/100004152","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000780","name":"European Commission","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000780","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100007352","name":"Staatssekretariat f\u00fcr Bildung, Forschung und Innovation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100007352","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100018693","name":"HORIZON EUROPE Framework Programme","doi-asserted-by":"publisher","award":["101057746"],"award-info":[{"award-number":["101057746"]}],"id":[{"id":"10.13039\/100018693","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","tipsro.science","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Technical Innovations & Patient Support in Radiation Oncology"],"published-print":{"date-parts":[[2026,6]]},"DOI":"10.1016\/j.tipsro.2026.100393","type":"journal-article","created":{"date-parts":[[2026,3,22]],"date-time":"2026-03-22T23:06:17Z","timestamp":1774220777000},"page":"100393","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Dosimetric comparison of the shoulder region between paired photon and proton plans in breast cancer patients"],"prefix":"10.1016","volume":"38","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3204-2443","authenticated-orcid":false,"given":"Yuqin","family":"Liang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karolien","family":"Verhoeven","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gloria","family":"Vilches-Freixas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sophie C.J.","family":"Bosma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard","family":"Canters","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7912-3171","authenticated-orcid":false,"given":"Femke E.","family":"Froklage","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6869-9733","authenticated-orcid":false,"given":"Ruud","family":"Houben","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John H.","family":"Maduro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jelle","family":"Overbosch","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9866-0776","authenticated-orcid":false,"given":"Joan J.","family":"Penninkhof","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Margriet G.A.","family":"Sattler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1264-4693","authenticated-orcid":false,"given":"Janine M.","family":"Simons","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nanna M.","family":"Sijtsema","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rozemarijn","family":"Vliegenthart","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne P.G.","family":"Crijns","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3096-5642","authenticated-orcid":false,"given":"Sofia","family":"Rivera","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9173-279X","authenticated-orcid":false,"given":"Liesbeth J.","family":"Boersma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"8","key":"10.1016\/j.tipsro.2026.100393_b0005","doi-asserted-by":"crossref","first-page":"1075","DOI":"10.1001\/jamaoncol.2015.5805","article-title":"Postoperative radiotherapy after breast-conserving surgery for early-stage breast cancer a review","volume":"2","author":"Speers","year":"2016","journal-title":"JAMA Oncol"},{"key":"10.1016\/j.tipsro.2026.100393_b0010","doi-asserted-by":"crossref","unstructured":"Early Breast Cancer Trialists' Collaborative G. Radiotherapy to regional nodes in early breast cancer: an individual patient data meta-analysis of 14 324 women in 16 trials. Lancet, 2023. 402(10416): p. 1991-2003. DOI: 10.1016\/S0140-6736(23)01082-6.","DOI":"10.1016\/S0140-6736(23)01082-6"},{"issue":"1","key":"10.1016\/j.tipsro.2026.100393_b0015","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s10549-008-0246-4","article-title":"Magnitude of late effects of breast cancer treatments on shoulder function: a systematic review","volume":"116","author":"Levangie","year":"2009","journal-title":"Breast Can Res Treat"},{"issue":"1","key":"10.1016\/j.tipsro.2026.100393_b0020","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1016\/j.radonc.2017.10.033","article-title":"Late normal tissue effects in the arm and shoulder following lymphatic radiotherapy: results from the UK START (Standardisation of Breast Radiotherapy) trials","volume":"126","author":"Haviland","year":"2018","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.tipsro.2026.100393_b0025","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1016\/j.radonc.2018.07.006","article-title":"Impact of modern-day axillary treatment on patient reported arm morbidity and physical functioning in breast cancer patients","volume":"131","author":"Gregorowitsch","year":"2019","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.tipsro.2026.100393_b0030","article-title":"Health-related quality of life (HRQoL) after different axillary treatments in women with breast cancer: a 1-year longitudinal cohort study","author":"Vrancken Peeters","year":"2023","journal-title":"Qual Life Res"},{"issue":"11","key":"10.1016\/j.tipsro.2026.100393_b0035","doi-asserted-by":"crossref","first-page":"1051","DOI":"10.1056\/NEJMoa2412063","article-title":"Axillary surgery in breast cancer \u2014 primary results of the INSEMA trial","volume":"392","author":"Reimer","year":"2025","journal-title":"N Engl J Med"},{"key":"10.1016\/j.tipsro.2026.100393_b0040","doi-asserted-by":"crossref","DOI":"10.1097\/JS9.0000000000001278","article-title":"Incidence and risk factors of breast cancer-related lymphedema in Korea: a nationwide retrospective cohort study","author":"Ahn","year":"2024","journal-title":"Int J Surg"},{"key":"10.1016\/j.tipsro.2026.100393_b0045","doi-asserted-by":"crossref","DOI":"10.1016\/j.eclinm.2024.102441","article-title":"Multinational Association of Supportive Care in Cancer (MASCC) clinical practice guidance for the prevention of breast cancer-related arm lymphoedema (BCRAL): international Delphi consensus-based recommendations","volume":"68","author":"Wong","year":"2024","journal-title":"eClinicalMedicine"},{"issue":"1","key":"10.1016\/j.tipsro.2026.100393_b0050","doi-asserted-by":"crossref","DOI":"10.1001\/jamanetworkopen.2024.55383","article-title":"External validation of a 5-factor risk model for breast cancer-related lymphedema","volume":"8","author":"Lin","year":"2025","journal-title":"JAMA Netw Open"},{"issue":"1","key":"10.1016\/j.tipsro.2026.100393_b0055","article-title":"Risk factors of unilateral breast cancer-related lymphedema: an updated systematic review and meta-analysis of 84 cohort studies","volume":"31","author":"Shen","year":"2023","journal-title":"Support Care Cancer"},{"key":"10.1016\/j.tipsro.2026.100393_b0060","doi-asserted-by":"crossref","DOI":"10.1016\/j.breast.2024.103812","article-title":"A systematic review and meta-analysis of risk factors influencing patient-reported arm symptoms post-breast cancer treatment: accounting for radiotherapy impact","volume":"78","author":"Liang","year":"2024","journal-title":"Breast"},{"issue":"3","key":"10.1016\/j.tipsro.2026.100393_b0065","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1016\/j.ijrobp.2019.06.2509","article-title":"Determining the organ at risk for lymphedema after regional nodal irradiation in breast cancer","volume":"105","author":"Gross","year":"2019","journal-title":"Int J Radiat Oncol Biol Phys"},{"issue":"2","key":"10.1016\/j.tipsro.2026.100393_b0070","doi-asserted-by":"crossref","first-page":"452","DOI":"10.1016\/j.ijrobp.2023.04.003","article-title":"The axillary lateral vessel thoracic junction is not an organ-at-risk for breast cancer related lymphedema","volume":"117","author":"Healy","year":"2023","journal-title":"Int J Radiat Oncol Biol Phys"},{"issue":"4","key":"10.1016\/j.tipsro.2026.100393_b0075","doi-asserted-by":"crossref","first-page":"521","DOI":"10.3109\/0284186X.2014.880512","article-title":"Arm and shoulder morbidity following surgery and radiotherapy for breast cancer","volume":"53","author":"Johansen","year":"2014","journal-title":"Acta Oncol"},{"issue":"3","key":"10.1016\/j.tipsro.2026.100393_b0080","doi-asserted-by":"crossref","first-page":"S7","DOI":"10.1016\/j.ijrobp.2022.07.342","article-title":"Axillary-lateral thoracic vessel juncture radiotherapy dose constraints for predicting long-term lymphedema risk in patients with breast cancer","volume":"114","author":"Ko","year":"2022","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.tipsro.2026.100393_b0085","doi-asserted-by":"crossref","DOI":"10.1016\/j.ijrobp.2023.01.056","article-title":"Development and validation of a normal tissue complication probability model for lymphedema after radiotherapy in breast cancer","author":"Park","year":"2023","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.tipsro.2026.100393_b0090","article-title":"Incorporating axillary-lateral thoracic vessel juncture dosimetric variables improves model for predicting lymphedema in patients with breast cancer: a validation analysis","volume":"41","author":"Suk Chang","year":"2023","journal-title":"Clin Translat Radiat Oncol"},{"issue":"3","key":"10.1016\/j.tipsro.2026.100393_b0095","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1016\/j.radonc.2016.12.032","article-title":"Quantifying radiation dose delivered to individual shoulder muscles during breast radiotherapy","volume":"122","author":"Lipps","year":"2017","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.tipsro.2026.100393_b0100","doi-asserted-by":"crossref","first-page":"755","DOI":"10.2340\/1651-226X.2024.40084","article-title":"Intensity-modulated proton radiotherapy spares musculoskeletal structures in regional nodal irradiation for breast cancer: a dosimetric comparison","volume":"63","author":"Burlile","year":"2024","journal-title":"Acta Oncol"},{"key":"10.1016\/j.tipsro.2026.100393_b0105","doi-asserted-by":"crossref","DOI":"10.1016\/S0167-8140(19)31708-6","article-title":"Dosimetric comparison of protons and photons in musculoskeletal sparing during breast irradiation","author":"Prescott","year":"2019","journal-title":"Radiother Oncol"},{"issue":"7","key":"10.1016\/j.tipsro.2026.100393_b0110","article-title":"Protons versus photons for the treatment of chordoma","volume":"7","author":"El Sayed","year":"2021","journal-title":"Cochrane Database Syst Rev"},{"key":"10.1016\/j.tipsro.2026.100393_b0115","doi-asserted-by":"crossref","DOI":"10.1016\/j.radonc.2025.110998","article-title":"Selection of patients for proton therapy to reduce risk of second primary lung and breast cancer","volume":"210","author":"Boersma","year":"2025","journal-title":"Radiother Oncol"},{"issue":"4","key":"10.1016\/j.tipsro.2026.100393_b0120","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1016\/j.clon.2021.12.007","article-title":"Model-based selection for proton therapy in breast cancer: development of the national indication protocol for proton therapy and first clinical experiences","volume":"34","author":"Boersma","year":"2022","journal-title":"Clin Oncol"},{"issue":"1","key":"10.1016\/j.tipsro.2026.100393_b0125","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/j.radonc.2014.11.030","article-title":"ESTRO consensus guideline on target volume delineation for elective radiation therapy of early stage breast cancer","volume":"114","author":"Offersen","year":"2015","journal-title":"Radiother Oncol"},{"issue":"1","key":"10.1016\/j.tipsro.2026.100393_b0130","doi-asserted-by":"crossref","first-page":"23110","DOI":"10.1038\/s41598-023-50538-x","article-title":"Hybrid VMAT-3DCRT as breast cancer treatment improvement tool","volume":"13","author":"Voyant","year":"2024","journal-title":"Sci Rep"},{"key":"10.1016\/j.tipsro.2026.100393_b0135","article-title":"The use of hybrid techniques in whole-breast radiotherapy: a systematic review","volume":"21","author":"Karaca","year":"2022","journal-title":"Technol Can Res Treat"},{"issue":"2","key":"10.1016\/j.tipsro.2026.100393_b0140","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1080\/0284186X.2020.1825800","article-title":"Effect of breathing motion on robustness of proton therapy plans for left-sided breast cancer patients with indication for locoregional irradiation","volume":"60","author":"Klaassen","year":"2021","journal-title":"Acta Oncol"},{"key":"10.1016\/j.tipsro.2026.100393_b0145","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1016\/j.tipsro.2021.06.004","article-title":"Harmonization of breast cancer radiotherapy treatment planning in the Netherlands","volume":"19","author":"Hurkmans","year":"2021","journal-title":"Tech Innovat Patient Support Radiat Oncol"},{"key":"10.1016\/j.tipsro.2026.100393_b0150","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1016\/j.radonc.2019.08.005","article-title":"Practical robustness evaluation in radiotherapy \u2013 a photon and proton-proof alternative to PTV-based plan evaluation","volume":"141","author":"Korevaar","year":"2019","journal-title":"Radiother Oncol"},{"issue":"1","key":"10.1016\/j.tipsro.2026.100393_b0155","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1186\/s13014-022-02043-0","article-title":"Transparency in quality of radiotherapy for breast cancer in the Netherlands: a national registration of radiotherapy-parameters","volume":"17","author":"Maliko","year":"2022","journal-title":"Radiat Oncol"},{"key":"10.1016\/j.tipsro.2026.100393_b0160","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1016\/j.breast.2023.02.006","article-title":"Regional radiotherapy after primary systemic treatment for cN+ breast cancer patients","volume":"68","author":"Boersma","year":"2023","journal-title":"Breast"},{"issue":"9","key":"10.1016\/j.tipsro.2026.100393_b0165","doi-asserted-by":"crossref","first-page":"1201","DOI":"10.1016\/S1470-2045(22)00482-X","article-title":"De-escalation of radiotherapy after primary chemotherapy in cT1-2N1 breast cancer (RAPCHEM; BOOG 2010-03): 5-year follow-up results of a Dutch, prospective, registry study","volume":"23","author":"de Wild","year":"2022","journal-title":"Lancet Oncol"},{"issue":"6","key":"10.1016\/j.tipsro.2026.100393_b0170","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1016\/j.clon.2023.02.015","article-title":"Proton beam therapy in breast cancer patients: the UK PARABLE trial is recruiting","volume":"35","author":"Kirby","year":"2023","journal-title":"Clin Oncol (R Coll Radiol)"},{"issue":"10","key":"10.1016\/j.tipsro.2026.100393_b0175","doi-asserted-by":"crossref","first-page":"e025556","DOI":"10.1136\/bmjopen-2018-025556","article-title":"Pragmatic randomised clinical trial of proton versus photon therapy for patients with non-metastatic breast cancer: the radiotherapy comparative effectiveness (RadComp) consortium trial protocol","volume":"9","author":"Bekelman","year":"2019","journal-title":"BMJ Open"}],"container-title":["Technical Innovations & Patient Support in Radiation Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S240563242600020X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S240563242600020X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,7,17]],"date-time":"2026-07-17T07:22:43Z","timestamp":1784272963000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S240563242600020X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,6]]},"references-count":35,"alternative-id":["S240563242600020X"],"URL":"https:\/\/doi.org\/10.1016\/j.tipsro.2026.100393","relation":{},"ISSN":["2405-6324"],"issn-type":[{"value":"2405-6324","type":"print"}],"subject":[],"published":{"date-parts":[[2026,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Dosimetric comparison of the shoulder region between paired photon and proton plans in breast cancer patients","name":"articletitle","label":"Article Title"},{"value":"Technical Innovations & Patient Support in Radiation Oncology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.tipsro.2026.100393","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Author(s). Published by Elsevier B.V. on behalf of European Society for Radiotherapy & Oncology.","name":"copyright","label":"Copyright"}],"article-number":"100393"}}